Dose Rounding July 2016

Dose Rounding July 2016

Thames Valley Cancer Network Drug IV Concentration Rounding Rounding Rounding mg (mg/ml) (ml) (mg) entered on Aria if different Aflibercept 25 25 Banded - national Aldeslukin 1.1 0.1 0.11 0.1 Alemtuzumab 30 0.1 3 Amifostine 50 0 Amsacrine 5 1 5 Banded Arsenic trioxide 1 0 Banded - national Aspariginase 0 500 Azacitidine 25 0.2 5 Bendamustine 2.5 2.5 5 Banded - national Bevacizumab 25 1 25 Banded Bleomycin 5000iunits/ml 0.2 1000 Bleomycin IM 10000iunits/ml 1 10000 Bortezomib IV 1 0.1 0.1 Banded - national Bortezomib SC 2.5 Banded - national Brentuximab vedotin 5 5 5 Banded Busulphan 6 6 Banded - national Cabazitaxel 10 10 5 Banded - national Carboplatin 10 1 10 Banded - national Carfilzomib 2 1 2 Carmustine 3.3 3 9.9 10 Cetuximab 5 1 5 Banded Cisplatin 1 1 1 Banded - national Cladribine (Leustat) IV 1 0.2 0.2 Cladribine (Litak) subcut 2 0.1 0.2 Clofarabine 1 1 1 Banded - national Cyclophosphamide 20 1 20 Banded - national Cytarabine (200mg) 20 1 20 Banded - national Cytarabine (1g, 2g) 100 1 100 Banded - national Cytarabine IT 20 0.5 10 Cytarabine liposomal IT (Depocyte) 10 1 10 Dacarbazine 10 1 10 Banded - national Dactinomycin 1 0.1 0.1 Daratumumab 20 1 20 Daunorubicin 5 1 5 Banded - national Daunorubicin liposomal 2 1 2 Banded - national Docetaxel 20 1 20 Banded - national Doxorubicin 2 1 2 Banded - national Doxorubicin liposomal pegylated (Caelyx) 2 1 2 Banded - national Durvalumab 50 0.1 5 Epirubicin 2 1 2 Banded - national Eribulin 0.44 0.5 0.22 Banded Etoposide 20 0.5 10 Banded - national Etoposide liquid oral 20 1 20 Etoposide phosphate 10 1 10 Banded - national Fludarabine 25 0.2 5 Fluorouracil 25 1 25 Banded - national 11/08/2016 1 of 2 Thames Valley Cancer Network Drug IV Concentration Rounding Rounding Rounding mg (mg/ml) (ml) (mg) entered on Aria if different Fluorouracil 50 1 50 Banded - national Fluorouracil subconjunctival 25 0.2 5 Ganciclovir 50 1 50 Gemcitabine 100 1 200 Banded - national Gemtuzumab 1 0.5 0.5 Idarubicin 1 1 1 Banded - national Ifosfamide 80 1 80 Banded Mesna 100 1 100 Banded Ipilimumab 5 5 Banded Irinotecan 20 0.5 20 Banded - national Leucovorin 3 1 3 Melphalan 5 1 5 Banded - national Methotrexate 2.5 1 2.5 Banded - national Methotrexate 25 0.1 2.5 Banded - national Methotrexate 100 1 100 Banded - national Methotrexate IT 5 0.1 0.5 Mifamurtide 0.08 0.08 0.16 Mitomycin C 1 1 1 Banded - national Mitomycin C bladder 1 1 1 Mitomycin C ocular 0.4 0.5 0.2 Mitoxantrone 2 0.5 1 Banded - national Nelarabine 50 50 Banded Nivolumab 10 Banded Obinutuzumab 25 1 25 Ofatumumab 20 1 20 Oxaliplatin 5 1 5 Banded - national Paclitaxel 6 1 6 Banded - national Paclitaxel albumin bound 5 20 Banded - national Panitumumab 20 0.5 10 Banded Pembrolizumab Banded Pemetrexed 25 1 25 Banded - national Raltitrexed 0.5 1 0.5 Rituximab 10 1 100 Banded - national Romidepsin 5 Banded - national Siltuximab 20 0.5 10 Streptozocin 100 0.1 100 Banded - national Thiotepa 10 Banded - national Topotecan 1 0.1 0.1 Banded - national Trabectedin 0.05 1 0.05 Trastuzumab 21 1 21 Banded Trastuzumab emtandine 20 Banded Treosulfan 50 1 50 Banded Vinblastine 1 0.5 0.5 Banded - national Vincristine 1 0.1 0.1 Banded - national Vindesine 1 0.5 0.5 Banded - national Vinflunine 25 1 25 Banded - national Vinorelbine 10 0.5 5 Banded - national 11/08/2016 2 of 2.

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