Medication Review Blood and Blood Formation Products Pharmacy Technician Training Systems © Passassured, LLC PassAssured's Pharmacy Technician Training Systems Medication Review, Bloos and Blood Formation Products PassAssured's Pharmacy Technician Training Program Medication Review Blood and Blood Formation Products Click Here to Print Topic Help File , .pdf Click Here for Glossary Index! (Internet Access is Required for this Feature) Definitions Therapeutic Classes Pass Assured, LLC, Pharmacy Technician Training Systems Copyright © Pass Assured, LLC, Web Site - http://www.passassured.com -o- p2 ________________________________________________________________ © PassAssured, LLC - Serving the Pharmacy Technician Commuinty www.passassured.com PassAssured's Pharmacy Technician Training Systems PassAssured's Pharmacy Technician Training Program Medication Review Blood and Blood Formation Products Click Here to Print Topic Help File , .pdf Click Here for Glossary Index! (Internet Access is Required for this Feature) Definitions Blood A mixture of water, cells, proteins, and dissolved salts. Blood serves as the transportation system for hormones, nutrients, and waste products within the body. Iron Deficiency Anemia Anemia due to a decrease in circulating red blood cells and resulting in decreased delivery of oxygen to body tissues. Treated with iron salts (ferrous sulfate) Megaloblastic anemia Anemia due to increased circulation of immature abnormal red blood cells resulting in decreased delivery of oxygen to body tissues. Treated with specific vitamins and minerals depending on which ones are needed (vitamin B-12, folic acid). Therapeutic Classes Anticoagulants Use Deep vein thrombosis (DVT) Pulmonary emboli Atrial fibrillation with embolism Prophylaxis of systemic emboli after myocardial infarction p3 ________________________________________________________________ © PassAssured, LLC - Serving the Pharmacy Technician Commuinty www.passassured.com PassAssured's Pharmacy Technician Training Systems Mechanism of Action Stop or slow the normal blood clotting processes Patient Information Instruct patient not to take aspirin or any new medications (including non- prescription medications) without his/her provider's knowledge. Side Effects Excess bleeding Examples: Warfarin (Coumadin) - Legend Drug Heparin Enoxaparin (Lovenox) - Legend Drug Danapariod (Orgaran) - Legend Drug Dalteparin (Fragmin) - Legend Drug Anisindione (Miradon) - Legend Drug Dicumarol (Dicumarol) - Legend Drug Tinzaparin (Innohep) - Legend Drug Desirudin (Iprivask) - Legend Drug) Lepirudin (Refludan) - Legend Drug Argatroban - Legend Drug Bivalirudin (Angiomax) - Legend Drug Fondaparinux (Arixtra) - Legend Drug Hemostatics Uses Treatment of excessive bleeding (e.g., surgical bleeding, hemophilia, vitamin K deficiency) Mechanism of Action Affects the blood clotting process Examples: Gelatin (Gelfoam) - Legend Drug Thrombin (Thrombinar) - Legend Drug p4 ________________________________________________________________ © PassAssured, LLC - Serving the Pharmacy Technician Commuinty www.passassured.com PassAssured's Pharmacy Technician Training Systems Aminocaproic acid (Amicar) - Legend Drug Phytonadione (Mephyton) Vitamin K - Legend Drug Factor VII (Monoclate) - Legend Drug Aprotinin (Trasylol) - Legend Drug Tranexamic acid (Cyklokapron) - Legend Drug Antithrombotics Use To decrease platelet aggregation (stickiness) and to decrease unwanted clot formation (e.g., heart attack prevention) Examples: Aspirin (Anacin, Ascriptin, Bayer, Bufferin, Ecotrin) - OTC Drugs Dipyridamole (Persantine) - Legend Drug Clopidogrel (Plavix) - Legend Drug Ticlopidine (Ticlid) - Legend Drug Thrombolytics Use To dissolve existing blood clots To decrease the muscle damage associated with heart attacks To treat pulmonary emboli Side Effect: Excessive bleeding Examples: TPA (Alteplase) - Legend Drug Streptokinase (Streptase) - Legend Drug APSAC (Eminase) - Legend Drug TPA (Activase) - Legend Drug Reteplase (Retevase) - Legend Drug Urokinase (Abbokinase) - Legend Drug p5 ________________________________________________________________ © PassAssured, LLC - Serving the Pharmacy Technician Commuinty www.passassured.com PassAssured's Pharmacy Technician Training Systems Hemorrheologic Agents Use Intermittent claudication - severe cramping in legs Mechanism of Action Decrease blood viscosity and help to increase blood flow to areas of need Side Effects Nausea/vomiting Dizziness Example: Pentoxifylline (Trental) - Legend Drug Antianemics Use To treat anemia caused by iron or vitamin deficiencies (e.g., megaloblastic anemia) Patient Information Take with meals to avoid stomach upset Side Effects Diarrhea or constipation Nausea/vomiting Examples: Iron Sulfate (Slow-Fe) - OTC Drug Ferrous Gluconate (iron supplement) - OTC Drug Folic Acid - OTC Drug Thiamine (Vitamin B6) - OTC Drug Cyanocobalamin (Vitamin B-12) - tablets OTC Drug/ injection Legend Drug Colony Stimulating Factor p6 ________________________________________________________________ © PassAssured, LLC - Serving the Pharmacy Technician Commuinty www.passassured.com PassAssured's Pharmacy Technician Training Systems Filgrastim (Neupogen) - Legend Drug given to cancer patients for bone marrow transplants must be refrigerated. Pass Assured, LLC, Pharmacy Technician Training Systems Copyright © Pass Assured, LLC, Web Site - http://www.passassured.com -o- p7 ________________________________________________________________ © PassAssured, LLC - Serving the Pharmacy Technician Commuinty www.passassured.com.