Bio T2, Unit 5: Cell Growth and Reproduction (Mitosis & Meiosis) ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Biology: Term 2, Unit 5 ​ ​ ​ ​ ​ ​ ​ ​ Topic: Cell Growth and Reproduction (Mitosis & Meiosis) ​ ​​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Duration: Traditional (50 minute periods): 13 - 17 days (adjust to student needs using professional discretion) ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Block (90 minute periods): 6 - 8 days (adjust to student needs using professional discretion) ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Eligible Content ​ ​ This is what the State of Pennsylvania wants your students to know and be able to do by the end of the unit. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 1. Cell Cycle--BIO.B.1.1.1 Describe the events that occur during the cell cycle: interphase, nuclear division (i.e., mitosis or ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ meiosis), cytokinesis. ​ ​ 2. Mitosis and Meiosis--BIO.B.1.1.2 Compare the processes and outcomes of mitotic and meiotic nuclear divisions. ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 3. DNA Replication--BIO.B.1.2.1 Describe how the process of DNA replication results in the transmission and/or ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ conservation of genetic information. ​ ​ ​ ​ ​ ​ 4. Genes, Alleles, and Chromosomes--BIO.B.1.2.2 Explain the functional relationships between DNA, genes, alleles, and ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ chromosomes and their roles in inheritance. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Performance Objectives ​ ​ These are examples, created by SDP teachers, of how you may translate the eligible content into learning goals for your ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ classroom. 1. SWBAT use models IOT illustrate the role of the cell cycle, cellular division (mitosis), and differentiation in producing ​ ​​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ and maintaining complex organisms. ​ ​ ​ ​ ​ ​ 2. SWBAT compare mitotic and meiotic nuclear divisions IOT differentiate between their processes and outcomes. ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 3. SWBAT describe the process of DNA replication IOT explain the conservation of genetic information. ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 4. SWBAT explain the functional relationships between DNA, genes, alleles, and chromosomes IOT articulate their roles ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ in inheritance. ​ ​ Key Terms and Definitions ​ ​ ​ ​ ​ ​ All key terms and definitions come from the document Keystone Exams: Biology Assessment Anchors and Eligible Content with ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Sample Questions and Glossary, PDE 2011. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 1. Cell Cycle: The series of events that take place in a cell leading to its division and duplication. The main phases of the ​ ​ ​ ​​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ cell cycle are interphase, nuclear division, and cytokinesis. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 2. Chromosomes: A single piece of coiled DNA and associated proteins found in linear forms in the nucleus of ​ ​​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ eukaryotic cells and circular forms in the cytoplasm of prokaryotic cells; contains genes that encode traits. Each species ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ has a characteristic number of chromosomes. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 3. Crossing-over: An exchange of genetic material between homologous chromosomes during anaphase I of meiosis; ​ ​​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ contributes to the genetic variability in gametes and ultimately in offspring. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 4. Cytokinesis: The final phase of a cell cycle resulting in the division of the cytoplasm ​ ​​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 5. Deoxyribonucleic Acid (DNA): A biological macromolecule that encodes the genetic information for living organisms ​ ​ ​ ​ ​ ​​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ and is capable of self replication and the synthesis of ribonucleic acid (RNA). ​ ​ ​ ​ ​ ​ ​ ​ - ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 6. DNA Replication: the process in which DNA makes a duplicate copy of itself. ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 7. Gamete: a specialized cell (egg or sperm) used in sexual reproduction containing half the normal number of ​ ​​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ chromosomes of a somatic cell. ​ ​ ​ ​ ​ ​ ​ ​ 8. Gene recombination: A natural process in which a nucleic acid molecule (usually DNA but can be RNA) is broken and ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ then joined to a different molecule; a result of crossing over. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ - 9. Interphase: The longest lasting phase of the cell cycle in which a cell performs the majority of its functions, such as ​ ​​ ​ ​ ​ - ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ preparing for nuclear division and cytokinesis. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ Bio T2, Unit 5: Cell Growth and Reproduction (Mitosis & Meiosis) ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 10. Meiosis: A two phase nuclear division that results in the eventual production of gametes with half the normal number ​ ​​ ​ ​ ​ - ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ of chromosomes. ​ ​ 11. Mitosis: A nuclear division resulting in the production of two somatic cells having the same genetic complement as ​ ​​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ the original cell ​ ​ ​ ​ 12. Semiconservative replication: The process in which the DNA molecule uncoils and separates into two strands. Each ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ original strand becomes a template on which a new strand is constructed, resulting in two DNA molecules identical to ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ the original DNA molecule. ​ ​ ​ ​ ​ ​ Starting Points ​ ​ An overview of how the content and skills of this unit connect to students' prior knowledge. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 1. Cell Cycle--BIO.B.1.1.1 ​ ​​ ​ ​ ​ Students should already know (from Unit 1) that systems of specialized cells within organisms help them perform the essential ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ functions of life. In this unit, students will learn that cellular division and differentiation produce and maintain a complex ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ organism composed of systems of tissues and organs that work together to meet the needs of the whole organism. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 2. Mitosis and Meiosis--BIO.B.1.1.2 ​ ​​ ​ ​ ​ ​ ​ This unit covers both mitosis and meiosis. Students should already know that organisms reproduce, either sexually or ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ asexually, and transfer their genetic information to their offspring. In this unit, they will learn how the replication of DNA before ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ cell division ensures the production of two genetically identical daughter cells and how meiosis leads to the genetic ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ recombination necessary for sexual reproduction. ​ ​ ​ ​ ​ ​ ​ ​ 3. DNA Replication--BIO.B.1.2.1 ​ ​​ ​ ​ ​ Students may have learned about the role of DNA in Unit 1, and the structure of the DNA molecule (or nucleotides in general) ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ in Unit 2,. In this unit students will learn how the structure of DNA allows for it to be easily and accurately replicated. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 4. Genes, Alleles, and Chromosomes--BIO.B.1.2.2 ​ ​​ ​ ​ ​ ​ ​ ​ ​ Students should already know that genes are located on chromosomes, but the physical and functional relationships between ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ genes, alleles, DNA, and chromosomes is something most students need to review frequently. By the end of the unit, students ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ should know that each chromosome consists of a single very long DNA molecule, each gene on the chromosome is a particular ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ segment of that DNA, and alleles are different variations of a gene. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 1. 1 Instructional Resources ​ ​ Learning activities and resources targeted to the eligible content of this unit. ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ 1. SWBAT use models IOT illustrate the role of the cell cycle, cellular division (mitosis), and differentiation in producing ​ ​​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ and maintaining complex organisms. ​ ​ ​ ​ ​ ​ a. Cell Cycle, Mitosis and Meiosis from CK-12. (Video, practice questions) ​ ​ ​ ​ ​ ​ ​ ​ ​ ​​ ​ ​ ​ ​ ​ ​ ​ ​ b. Cell Cycle tutorial from Cells Alive. Animation, powerpoint, Cancer Cell Cam, worksheets, quiz. ​ ​