Visual effect of the combined correction of spherical and longitudinal chromatic aberrations Pablo Artal 1,* , Silvestre Manzanera 1, Patricia Piers 2 and Henk Weeber 2 1Laboratorio de Optica, Centro de Investigación en Optica y Nanofísica (CiOyN), Universidad de Murcia, Campus de Espinardo, 30071 Murcia, Spain 2AMO Groningen, Groningen, The Netherlands *[email protected] Abstract: An instrument permitting visual testing in white light following the correction of spherical aberration (SA) and longitudinal chromatic aberration (LCA) was used to explore the visual effect of the combined correction of SA and LCA in future new intraocular lenses (IOLs). The LCA of the eye was corrected using a diffractive element and SA was controlled by an adaptive optics instrument. A visual channel in the system allows for the measurement of visual acuity (VA) and contrast sensitivity (CS) at 6 c/deg in three subjects, for the four different conditions resulting from the combination of the presence or absence of LCA and SA. In the cases where SA is present, the average SA value found in pseudophakic patients is induced. Improvements in VA were found when SA alone or combined with LCA were corrected. For CS, only the combined correction of SA and LCA provided a significant improvement over the uncorrected case. The visual improvement provided by the correction of SA was higher than that from correcting LCA, while the combined correction of LCA and SA provided the best visual performance. 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