Table S1. Putative miR-322 target transcripts which is highly expressed in MGCs ________________________________________________________________________________ 0610037L13Rik, 1700037H04Rik, 2310061I04Rik, 2810006K23Rik, Abcc5, Abhd16a, Acbd3, Acox1, Acsbg1, Acsl4, Actr1a, Actr2, Adck5, Adh5, Adrbk1, Aff4, Agk, Ahcyl1, Akap11, Akap7, Akirin1, Alg3, Amfr, Ammecr1, Amotl2, Ankfy1, Ankhd1, Ankrd52, Ap2a1, Ap2b1, Ap3b1, Ap3d1, App, Arcn1, Arf3, Arfgap2, Arhgap12, Arhgap5, Arhgdia, Arhgef11, Arih1, Arl2, Arl3, Arl8b, Armcx6, Asap1, Asnsd1, Atf6, Atg13, Atg4b, Atp13a3, Atp5g1, Atp6v1a, Atxn2, Atxn7l3, Atxn7l3b, AW549877, B4galt1, B4galt7, Bace1, Bag5, Baiap2, Baz2a, BC037034, Bcl2l1, Bcl2l2, Bfar, Bmpr1a, Bptf, Brd2, Brd4, Brpf3, Btbd3, Btg2, Cab39, Cacna2d1, Calm1, Capns1, Caprin1, Capza2, Carm1, Caskin1, Cbfa2t3, Cbx5, Cbx6, Cc2d1b, Ccdc127, Ccdc6, Ccnd2, Ccnt2, Ccnyl1, Cd164, Cd2ap, Cdc25a, Cdc27, Cdc37l1, Cdc42se2, Cdca4, Cdipt, Cdk5rap3, Cdk8, Cdk9, Cdv3, Celf1, Cfl2, Chchd3, Chd6, Chmp1a, Chmp7, Chordc1, Chpf, Chpt1, Chst8, Chtf8, Cisd2, Clasrp, Clcn3, Clstn1, Cmpk1, Cnih2, Cnot1, Cnot2, Col4a3bp, Cope, Cops2, Cops7a, Cops7b, Copz1, Coq6, Cpd, Crebzf, Crim1, Crk, Crkl, Csde1, Cse1l, Ctnnb1, Cul4a, Cul4b, Cxx1a, Cxx1b, Cxx1c, D15Ertd621e, D2hgdh, Dcaf7, Dcbld2, Dcp1a, Dctn5, Ddost, Ddr1, Ddx39, Ddx3x, Ddx6, Dedd, Dhdds, Dhx16, Diap1, Dido1, Dlst, Dmtf1, Dnaja2, Dnajb14, Dnajb2, Dnajc1, Dnajc16, Dnajc25, Dph3, Dpm1, Dpp9, Dpy19l4, Dsel, Dtl, Dvl1, Dync1li2, Dynll2, Dynlt3, Dyrk1a, Dyrk1b, Ebna1bp2, Edc4, Eftud2, Egln2, Eif1a, Eif2b2, Eif2s1, Eif3a, Eif4b, Eif4e, Eif4g1, Eif4g2, Eif5b, Elmo2, Elovl5, Enah, Enc1, Entpd4, Erlin2, Erp29, Etnk1, Etv6, Evi5, Extl3, Faf2, Fam120a, Fam122a, Fam126a, Fam133b, Fam134a, Fam160b2, Fam171a1, Fam178a, Fam53c, Fam60a, Fasn, Fastk, Fbxo21, Fermt2, Fkbp1a, Fkbp5, Fkrp, Flna, Fndc3b, Fnta, Fosl2, Furin, Gabbr1, Gak, Galnt1, Galnt7, Gatad2a, Gbf1, Gclm, Gga2, Gga3, Gigyf1, Git1, Glud1, Gna12, Gna13, Gnai3, Gns, Gpaa1, Gpatch8, Gpn1, Gsk3b, Gtpbp2, H6pd, Haus5, Hdgf, Hdhd2, Hectd1, Herc3, Hiatl1, Higd1a, Hipk3, Hira, Hmmr, Hnrnpa1, Hnrnpa2b1, Hsd17b7, Hspg2, Hsph1, Iars, Idh3a, Igf1, Igf1r, Igf2r, Ihh, Ing4, Ino80b, Insr, Ints3, Ip6k1, Ipo4, Isoc1, Itgav, Itgb1, Itpr1, Jmy, Kank1, Kbtbd2, Kbtbd4, Kcmf1, Kif1b, Kif1c, Kif23, Kif5b, Klc1, Klc4, Kpna1, Kpna3, Kpna4, Lamc1, Larp1, Lats1, Lats2, Leng8, Limk2, Lims1, Lnpep, Lrch4, Lrig1, Lrp5, Lrp6, Lrrc58, Lrrfip2, Lsg1, Lsm14b, Ly6e, Lypla2, Lyrm5, Macf1, Man2a1, Man2a2, Map1lc3b, Map2k1, Map2k3, Map3k3, Map3k4, Mapk1ip1l, Mapk3, Mapk9, Mapkap1, Mapkapk3, Mapre1, March6, Mark2, Med1, Med24, Med28, Mesdc2, Metap1, Mfn2, Mfsd1, Mfsd10, Mfsd4, Mink1, Mknk1, Mllt10, Mllt6, Mlxip, Mms19, Mob4, Morc2a, Mov10, Mpp1, Mrap, Mras, Mrps25, Msl1, Mtap, Mtch2, Mtmr2, Mtmr3, Mtmr4, Mtpn, Mxd4, Myadm, Myo1c, N4bp1, N6amt1, Naa15, Nbr1, Ncaph, Ndor1, Nf2, Nfat5, Nfatc3, Nfe2l1, Nfrkb, Nipsnap1, Nop56, Nras, Nrbp1, Nrn1, Nucks1, Nudt4, Numb, Nup50, Nusap1, Ocrl, Ogt, Otud4, Otud6b, Pacsin2, Pafah1b1, Pafah1b2, Paip2b, Pam, Pan3, Pappa, Patl1, Patz1, Pbxip1, Pcid2, Pcm1, Pcmt1, Pdap1, Pdcd4, Pdcd6ip, Pdia6, Peli2, Pex13, Pex5, Pfas, Pfkl, Pgm2, Phf13, Phf21a, Pi4kb, Pias2, Pik3r1, Pisd, Pitpna, Pkd1, Pkdcc, Plagl1, Plekha1, Plrg1, Plxna1, Plxnc1, Pmpcb, Pnpla6, Pom121, Ppap2b, Ppif, Ppig, Ppih, Ppm1a, Ppme1, Ppp1r11, Ppp2r1a, Ppp2r5c, Ppp6c, Ppt1, Prkrir, Prr11, Prrc2c, Pskh1, Psme3, Ptpn11, Ptprd, Pum2, Purb, Pvrl1, Qars, Qk, R3hdm2, Rab10, Rab14, Rab22a, Rab4b, Rab5b, Rabac1, Rabep1, Rad23b, Rad51, Raf1, Ralgapb, Ranbp3, Rap2c, Rapgef1, Rasgef1b, Rassf2, Rbbp6, Rbfox2, Rbm12, Rbm39, Rbm6, Rbms1, Rcor3, Repin1, Rere, Rfc1, Rfwd2, Rgp1, Rhobtb3, Ric8, Rimklb, Rnf10, Rnf123, Rnf41, Rnf8, Rock2, Rpl22, Rpl6, Rprd1b, Rps6ka3, Rptor, Rrnad1, Rtf1, Rtn3, Rtn4, Rybp, Samd10, Samd8, Sbf1, Scoc, Sdf2, Sec16a, Sec61a1, Sec62, Secisbp2l, Seh1l, Sel1l3, Sept2, Sept6, Serbp1, Serinc3, Sesn1, Setd3, Setd5, Sgcb, Sgk1, Shoc2, Sidt2, Sil1, Ski, Slc12a6, Slc20a2, Slc25a22, Slc25a37, Slc2a1, Slc35c2, Slc39a10, Slc45a4, Smad3, Smad5, Smarca1, Smarcd2, Smc5, Smek2, Smg7, Sms, Smyd5, Snx27, Son, Spag7, Spns1, Spred1, Spsb4, Sptlc1, Spty2d1, Srp14, Srpk1, Srpr, Srprb, Srsf11, Ssr1, Stim1, Stradb, Stxbp6, Sumo3, Suz12, Syde1, Syne2, Sypl, Tacc1, Tarbp2, Tars2, Tbc1d10b, Tbk1, Tbp, Tcta, Tesk1, Tet3, Tgoln1, Tk2, Tlk1, Tm7sf2, Tmem109, Tmem135, Tmem183a, Tmem184b, Tmem201, Tmem206, Tmem33, Tmem39b, Tmem55a, Tmem55b, Tmem87a, Tmem87b, Tmtc4, Tnfaip1, Tnpo1, Tnpo3, Tollip, Top2b, Tpt1, Tram1, Trim35, Trim39, Trip10, Trp53inp2, Tspyl2, Ttc14, Tuba1a, Tubgcp3, Txnl4a, Ubap1, Ube2g2, Ube2j1, Ube2q1, Ube2v1, Ube4b, Ubfd1, Ubl5, Ubn2, Ubr3, Ubr4, Uggt1, Unc119b, Usp12, Usp14, Usp19, Usp25, Usp7, Usp9x, Vamp8, Vapb, Vat1, Vbp1, Vegfa, Vps37c, Vti1b, Wasl, Wbp11, Wdr82, Whsc1, Wibg, Wipi2, Wnt4, Wsb1, Wsb2, Xpr1, Ythdc1, Ywhah, Ywhaq, Zc3h11a, Zdhhc18, Zdhhc21, Zer1, Zfand3, Zfp326, Zfp362, Zfp523, Zfp687, Zmym2, Zmynd11, Znrf2, Zyx ________________________________________________________________________________ 1 Table S2. Biological processes (GO terms) significantly associated with the putative miR-322 targets expressed in MGCs TermID Term Q Symbols GO:0044267 cellular protein metabolic process 1.24E-19 Adh5,Adrbk1,Amfr,App,Arih1,Atg4b,Atxn7l3,B4galt1,B4galt7,Baz2a,Bfar,Bmpr1a,Brd4,Brpf3,Bt g2,Cab39,Carm1,Cd2ap,Cdc25a,Cdc27,Cdc37l1,Cdk5rap3,Cdk8,Cdk9,Chordc1,Cops7a,Cops 7b,Cul4a,Cul4b,D2hgdh,Ddost,Ddr1,Ddx3x,Dnaja2,Dnajb2,Dnajc1,Dpm1,Dpy19l4,Dtl,Dyrk1a,D yrk1b,Egln2,Eif2b2,Eif2s1,Eif3a,Eif4e,Eif4g2,Eif5b,Enc1,Erlin2,Erp29,Faf2,Fastk,Fkbp1a,Fkbp5 ,Fkrp,Fnta,Furin,Galnt1,Galnt7,Gpaa1,Gsk3b,Gtpbp2,Hectd1,Herc3,Hipk3,Hsph1,Iars,Igf1,Igf1r ,Ing4,Insr,Itgav,Kcmf1,Larp1,Lats1,Lats2,Limk2,Man2a1,Map2k1,Map2k3,Map3k3,Map3k4,Ma pk3,Mapk9,Mapkapk3,March6,Mark2,Med1,Med24,Mesdc2,Mink1,Mknk1,Mrps25,Msl1,Mtmr2, Mtmr3,N6amt1,Naa15,Ocrl,Ogt,Otud4,Pam,Pcmt1,Pdcd6ip,Pdia6,Pias2,Pik3r1,Pkd1,Pkdcc,Pp ap2b,Ppif,Ppig,Ppih,Ppm1a,Ppme1,Ppp2r1a,Ppp2r5c,Ppp6c,Ppt1,Pskh1,Ptpn11,Raf1,Rassf2, Rbbp6,Rfwd2,Rnf10,Rnf41,Rnf8,Rock2,Rprd1b,Rps6ka3,Rtf1,Rybp,Sec16a,Setd3,Sgk1,Slc35c 2,Smad5,Smek2,Srpk1,Stradb,Sumo3,Suz12,Tbk1,Tesk1,Tet3,Tlk1,Tmem55a,Tmem55b,Tnfai p1,Trp53inp2,Ubap1,Ube2g2,Ube2j1,Ube2q1,Ube2v1,Ube4b,Ubl5,Ubr3,Ubr4,Usp12,Usp14,Us p19,Usp25,Usp7,Usp9x,Wdr82,Whsc1,Wipi2,Zdhhc18,Zdhhc21,Zer1,Znrf2 GO:0044260 cellular macromolecule metabolic process 6.15E-18 Adh5,Adrbk1,Ahcyl1,Amfr,App,Arih1,Atg4b,Atxn7l3,B4galt1,B4galt7,Baz2a,Bfar,Bmpr1a,Bptf,Br d4,Brpf3,Btg2,Cab39,Carm1,Cd2ap,Cdc25a,Cdc27,Cdc37l1,Cdk5rap3,Cdk8,Cdk9,Celf1,Chord c1,Chpf,Chst8,Cnot1,Cnot2,Cops7a,Cops7b,Crebzf,Csde1,Cul4a,Cul4b,D2hgdh,Dcp1a,Ddost, Ddr1,Ddx39,Ddx3x,Ddx6,Dhx16,Dnaja2,Dnajb2,Dnajc1,Dpm1,Dpy19l4,Dsel,Dtl,Dvl1,Dyrk1a,Dy rk1b,Ebna1bp2,Egln2,Eif2b2,Eif2s1,Eif3a,Eif4e,Eif4g2,Eif5b,Enc1,Erlin2,Erp29,Etv6,Faf2,Fastk ,Fkbp1a,Fkbp5,Fkrp,Flna,Fnta,Fosl2,Furin,Galnt1,Galnt7,Gatad2a,Gpaa1,Gsk3b,Gtpbp2,Hectd 1,Herc3,Hipk3,Hnrnpa1,Hnrnpa2b1,Hsph1,Iars,Igf1,Igf1r,Ihh,Ing4,Insr,Ints3,Itgav,Kcmf1,Larp1, Lats1,Lats2,Limk2,Man2a1,Map2k1,Map2k3,Map3k3,Map3k4,Mapk3,Mapk9,Mapkapk3,March 6,Mark2,Med1,Med24,Mesdc2,Mink1,Mknk1,Mms19,Mov10,Mrps25,Msl1,Mtmr2,Mtmr3,N6amt 1,Naa15,Nfat5,Nfatc3,Nfe2l1,Nop56,Nucks1,Ocrl,Ogt,Otud4,Pam,Pan3,Patl1,Patz1,Pcmt1,Pdc d6ip,Pdia6,Pgm2,Pias2,Pik3r1,Pkd1,Pkdcc,Plagl1,Plrg1,Ppap2b,Ppif,Ppig,Ppih,Ppm1a,Ppme1, Ppp2r1a,Ppp2r5c,Ppp6c,Ppt1,Pskh1,Ptpn11,Qk,Rad23b,Rad51,Raf1,Rassf2,Rbbp6,Rbm39,Re re,Rfwd2,Rnf10,Rnf41,Rnf8,Rock2,Rprd1b,Rps6ka3,Rtf1,Rybp,Sec16a,Setd3,Sgk1,Slc35c2,S mad3,Smad5,Smarca1,Smc5,Smek2,Son,Srpk1,Stradb,Sumo3,Suz12,Tarbp2,Tbk1,Tbp,Tesk1 ,Tet3,Tk2,Tlk1,Tmem55a,Tmem55b,Tnfaip1,Top2b,Trp53inp2,Txnl4a,Ubap1,Ube2g2,Ube2j1,U be2q1,Ube2v1,Ube4b,Ubl5,Ubr3,Ubr4,Usp12,Usp14,Usp19,Usp25,Usp7,Usp9x,Wbp11,Wdr82, Whsc1,Wibg,Wipi2,Ythdc1,Zdhhc18,Zdhhc21,Zer1,Zfp326,Znrf2 Table S2_2 2 GO:0006464 cellular protein modification process 3.26E-17 Adh5,Adrbk1,Amfr,App,Arih1,Atg4b,Atxn7l3,B4galt1,B4galt7,Baz2a,Bfar,Bmpr1a,Brd4,Brpf3,Bt g2,Cab39,Carm1,Cdc25a,Cdc27,Cdk5rap3,Cdk8,Cdk9,Cops7a,Cops7b,Cul4a,Cul4b,Ddost,Ddr 1,Dpm1,Dpy19l4,Dtl,Dyrk1a,Dyrk1b,Egln2,Eif2s1,Enc1,Fastk,Fkbp1a,Fkbp5,Fkrp,Fnta,Galnt1, Galnt7,Gpaa1,Gsk3b,Hectd1,Herc3,Hipk3,Igf1,Igf1r,Ing4,Insr,Itgav,Kcmf1,Lats1,Lats2,Limk2,M an2a1,Map2k1,Map2k3,Map3k3,Map3k4,Mapk3,Mapk9,Mapkapk3,March6,Mark2,Med1,Med2 4,Mink1,Mknk1,Msl1,Mtmr2,Mtmr3,N6amt1,Naa15,Ocrl,Ogt,Otud4,Pam,Pcmt1,Pias2,Pik3r1,Pk d1,Pkdcc,Ppap2b,Ppif,Ppig,Ppih,Ppm1a,Ppme1,Ppp2r1a,Ppp6c,Ppt1,Pskh1,Ptpn11,Raf1,Rass f2,Rbbp6,Rfwd2,Rnf10,Rnf41,Rnf8,Rock2,Rprd1b,Rps6ka3,Rtf1,Rybp,Sec16a,Setd3,Sgk1,Slc 35c2,Smad5,Smek2,Srpk1,Stradb,Sumo3,Suz12,Tbk1,Tesk1,Tet3,Tlk1,Tmem55a,Tmem55b,T nfaip1,Ube2g2,Ube2j1,Ube2q1,Ube2v1,Ube4b,Ubl5,Ubr3,Ubr4,Usp12,Usp14,Usp19,Usp25,Us p7,Usp9x,Wdr82,Whsc1,Wipi2,Zdhhc18,Zdhhc21,Zer1,Znrf2 GO:0036211 protein modification process 3.26E-17 Adh5,Adrbk1,Amfr,App,Arih1,Atg4b,Atxn7l3,B4galt1,B4galt7,Baz2a,Bfar,Bmpr1a,Brd4,Brpf3,Bt g2,Cab39,Carm1,Cdc25a,Cdc27,Cdk5rap3,Cdk8,Cdk9,Cops7a,Cops7b,Cul4a,Cul4b,Ddost,Ddr 1,Dpm1,Dpy19l4,Dtl,Dyrk1a,Dyrk1b,Egln2,Eif2s1,Enc1,Fastk,Fkbp1a,Fkbp5,Fkrp,Fnta,Galnt1, Galnt7,Gpaa1,Gsk3b,Hectd1,Herc3,Hipk3,Igf1,Igf1r,Ing4,Insr,Itgav,Kcmf1,Lats1,Lats2,Limk2,M an2a1,Map2k1,Map2k3,Map3k3,Map3k4,Mapk3,Mapk9,Mapkapk3,March6,Mark2,Med1,Med2 4,Mink1,Mknk1,Msl1,Mtmr2,Mtmr3,N6amt1,Naa15,Ocrl,Ogt,Otud4,Pam,Pcmt1,Pias2,Pik3r1,Pk d1,Pkdcc,Ppap2b,Ppif,Ppig,Ppih,Ppm1a,Ppme1,Ppp2r1a,Ppp6c,Ppt1,Pskh1,Ptpn11,Raf1,Rass f2,Rbbp6,Rfwd2,Rnf10,Rnf41,Rnf8,Rock2,Rprd1b,Rps6ka3,Rtf1,Rybp,Sec16a,Setd3,Sgk1,Slc 35c2,Smad5,Smek2,Srpk1,Stradb,Sumo3,Suz12,Tbk1,Tesk1,Tet3,Tlk1,Tmem55a,Tmem55b,T nfaip1,Ube2g2,Ube2j1,Ube2q1,Ube2v1,Ube4b,Ubl5,Ubr3,Ubr4,Usp12,Usp14,Usp19,Usp25,Us