Final Program Sponsored by the SIAM Activity Group on the Life Sciences. The SIAM Activity Group on the Life Sciences was established to foster the application of mathematics to the life sciences and research in mathematics that leads to new methods and techniques useful in the life sciences. The life sciences have become quantitative as new technologies facilitate collection and analysis of vast amounts of data ranging from complete genomic sequences of organisms to satellite imagery of forest landscapes on continental scales. Computers enable the study of complex models of biological processes. The activity group brings together researchers who seek to develop and apply mathematical and computational methods in all areas of the life sciences. It provides a forum that cuts across disciplines to catalyze mathematical research relevant to the life sciences and rapid diffusion of advances in mathematical and computational methods. The activity group organizes the biennial SIAM Conference on the Life Sciences as well as minisymposia at SIAM meetings and conferences. Every two years, the activity group also awards the SIAG/LS Early Career Prize to an outstanding early career researcher in the field of mathematics applied to the life sciences. Members of the SIAG/LS receive a complimentary subscription to the all-electronic, multimedia SIAM Journal on Applied Dynamical Systems. The activity group maintains a member directory and an electronic mailing list. 3600 Market Street, 6th Floor Philadelphia, PA 19104-2688 USA Telephone: +1-215-382-9800 Fax: +1-215-386-7999 Conference E-mail: [email protected] Conference Web: www.siam.org/meetings/ Membership and Customer Service: (800) 447-7426 (USA & Canada) or +1-215-382-9800 (worldwide) www.siam.org/meetings/ls18 SIAM Events Mobile App Scan the QR code with any QR reader and download the TripBuilder EventMobile™ app to your iPhone, iPad, iTouch or Android mobile device. You can also visit www.tripbuildermedia.com/apps/siamevents 2 SIAM Conference on the Life Sciences Table of Contents SIAM Registration Desk mathematics and computational sciences The SIAM registration desk is located community through their membership rd benefits. Corporate membership is more Program-at-a-Glance… in the Denmark Commons on the 3 than just a bundle of tangible products ..............................See separate handout Floor. Registration is open during the and services; it is an expression of General Information .............................2 following hours: support for SIAM and its programs. Get-togethers ........................................4 Sunday, August 5 SIAM is pleased to acknowledge its Minitutorial and Prize Ceremony .........5 5:00 PM - 8:00 PM corporate members and sponsors. In Invited Plenary Presentations ...............6 recognition of their support, non- Program Schedule ..............................10 Monday, August 6 member attendees who are employed by Poster Session ....................................34 7:00 AM - 3:00 PM the following organizations are entitled Speaker and Organizer Index .............56 to the SIAM member registration rate. Conference Budget ...Inside Back Cover Tuesday, August 7 Hotel Meeting Room Map ..Back Cover 7:45 AM - 3:00 PM Corporate/Institutional Members Organizing Committee Wednesday, August 8 The Aerospace Corporation 7:45 AM - 3:00 PM Co-Chairs Air Force Office of Scientific Research Alla Borisyuk Thursday, August 9 Amazon University of Utah, USA 7:45 AM - 3:00 PM Aramco Services Company Samuel Isaacson Boston University, USA Argonne National Laboratory Hotel Address Bechtel Marine Propulsion Laboratory Radisson Blu Minneapolis Organizing Committee 35 South 7th Street The Boeing Company Victoria Booth Minneapolis, Minnesota, USA CEA/DAM University of Michigan, USA Department of National Defence (DND/ Tom Chou Hotel Telephone Number CSEC) University of California Los Angeles, USA To reach an attendee or leave a message, DSTO- Defence Science and Peter Kim call +1-612-339-4900. If the attendee Technology Organisation University of Sydney, Australia is a hotel guest, the hotel operator can Exxon Mobil Doron Levy connect you with the attendee’s room. Hewlett-Packard University of Maryland, USA Huawei FRC French R&D Center Mark Lewis Hotel Check-in and Check- University of Alberta, Canada IBM Corporation out Times Laura Miller Check-in time is 3:00 PM. IDA Center for Communications University of North Carolina at Chapel Hill, Research, La Jolla Check-out time is 12:00 PM. USA IDA Center for Communications Jeffrey Sachs Research, Princeton Merck Research Laboratories, USA Child Care The Radisson Blu Minneapolis IFP Energies nouvelles Chuan Xue recommends Urban Sitters (https://www. Institute for Defense Analyses, Center Ohio State University, USA urbansitter.com/college-babysitters/ for Computing Sciences Shan Zhao university-of-minnesota) for attendees Lawrence Berkeley National Laboratory University of Alabama, USA interested in child care services. Attendees are responsible for making Lawrence Livermore National Labs their own child care arrangements. Conference Themes Lockheed Martin Los Alamos National Laboratory Biofluids and Biomechanics Biology of Disease Corporate Members Max-Planck-Institute for Dynamics of Cell and Systems Biology and Affiliates Complex Technical Systems Ecology and Evolution SIAM corporate members provide Mentor Graphics Molecular Bioscience and Biophysics their employees with knowledge about, National Institute of Standards and Neuroscience and Behavior access to, and contacts in the applied Technology (NIST) Physiology and Medicine SIAM Conference on the Life Sciences 3 National Security Agency (DIRNSA) Non-Member and $70 for a Non-Member wireless internet access in their guest Naval PostGrad Mini Speaker/Organizer) towards a rooms of the hotel. All conference SIAM membership. Contact SIAM attendees will have complimentary Oak Ridge National Laboratory, Customer Service for details or join at the wireless Internet access in the meeting managed by UT-Battelle for the Department of Energy conference registration desk. space of the hotel. If you are a SIAM member, it only costs $15 Sandia National Laboratories SIAM will also provide a limited number to join the SIAM Activity Group on the Life Schlumberger-Doll Research Sciences (SIAG/LS). As a SIAG/LS member, of email stations. United States Department of Energy you are eligible for an additional $15 discount U.S. Army Corps of Engineers, Engineer on this conference, so if you paid the SIAM Registration Fee Includes Research and Development Center member rate to attend the conference, you • Admission to all technical sessions might be eligible for a free SIAG/LS member- US Naval Research Labs ship. Check at the registration desk. • Business Meeting (open to SIAG/LS members) Free Student Memberships are available List current June 2018. • Coffee breaks daily to students who attend an institution that • Room set-ups and audio/visual is an Academic Member of SIAM, are equipment Funding Agency members of Student Chapters of SIAM, • Welcome Reception SIAM and the conference organizing or are nominated by a Regular Member • Poster Session committee wish to extend their thanks of SIAM. and appreciation to the U.S. National Join onsite at the registration desk, go to Science Foundation for its support of this www.siam.org/joinsiam to join online or Job Postings conference. download an application form, or contact Please check with the SIAM registration SIAM Customer Service: desk regarding the availability of job Telephone: +1-215-382-9800 postings or visit http://jobs.siam.org. (worldwide); or 800-447-7426 (U.S. and Canada only) Poster Participant Information Fax: +1-215-386-7999 The poster session is scheduled on E-mail: [email protected] Tuesday, August 7 from 7:00 PM to Postal mail: Society for Industrial and 9:00 PM. Poster presenters must set-up Applied Mathematics, 3600 Market their poster material on the 4’ x 8’ poster Join SIAM and save! boards in the Fjords 3 & 4 Rooms on the Street, 6th floor, Philadelphia, PA 19104- nd 2688 USA 2 floor between the hours of 3:00 PM Leading the applied on Monday, August 6 and 7:00 PM on mathematics community . Tuesday, August 7. All materials must SIAM members save up to $140 on full Standard Audio-Visual be posted by the official start time of the registration for the SIAM Conference Set-Up in Meeting Rooms session. Posters will remain on display on the Life Sciences (LS18)! Join SIAM does not provide computers for through Thursday, August 9. Posters your peers in supporting the premier any speaker. When giving an electronic must be removed by 10:00 AM on professional society for applied presentation, speakers must provide their Thursday, August 9. mathematicians and computational own computers. SIAM is not responsible scientists. SIAM members receive for the safety and security of speakers’ SIAM Books and Journals subscriptions to SIAM Review, SIAM computers. News and SIAM Unwrapped, and enjoy Please stop by the books booth to browse substantial discounts on SIAM books, A data (LCD) projector and screen will our newest titles, as well as textbooks, journal subscriptions, and conference be provided in all technical session classics and all-time bestsellers (all at registrations. meeting rooms. The data projectors discounted prices during the conference). support both VGA and HDMI We also have complimentary copies of If you are not a SIAM member and paid connections. Presenters requiring an the Non-Member or Non-Member SIAM journals. The books booth will alternate connection must provide their be staffed from 9:00 AM through 4:30 Mini Speaker/Organizer rate to attend the own adaptor. conference, you can apply the difference PM on Monday through Wednesday, between what you paid and what a Internet Access and 9:00 AM to 3:00 PM on Thursday. member would have paid ($140 for a If a SIAM books representative is Attendees booked within the SIAM room block will receive complimentary 4 SIAM Conference on the Life Sciences temporarily away from the booth, University of Michigan, Ann Arbor to connect with each other prior to, completed order forms and payment Great Fantasia in G Minor BWV 542 during and after conferences.