May 11, 2020 JONATHAN V. SWEEDLER UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Department of Chemistry Beckman Institute 600 S. Mathews Ave. 405 N. Mathews Ave. Urbana, IL 61801 Urbana, IL 61801 (217) 244-7359 (217) 244-4398 [email protected] http://www.scs.illinois.edu/chem/faculty/Jonathan_Sweedler.html APPOINTMENTS UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Center for Advanced Study Professor of Chemistry August 2013–present Director of the School of Chemical Sciences August 2012–present James R. Eiszner Family Endowed Chair in Chemistry August 2008–present Director, Carver Biotechnology Center September 2002–August 2012 William H. and Janet G. Lycan Professor of Chemistry November 2001–August 2008 Professor of Chemistry August 1999–October 2001 Associate Professor of Chemistry July 1996–July 1999 Assistant Professor of Chemistry July 1991–July 1996 Research emphasis is both analytical chemistry and the study of cell-cell signaling. The major areas of analytical technology development involve small volume peptidomics and metabolomics. Such measurements involve enhancements to capillary electrophoresis separation methods, laser-based detection methods, MALDI sampling techniques, nanoliter volume NMR and micro/nanofluidic sampling. The second group theme relates to cell-cell signaling. This includes neuroscience (the discovery of novel neurochemical pathways, new signaling molecules, their distribution, and function in a range of animal models) as well as quorum sensing and other aspects of cell-cell signaling in microbial communities. University of Illinois Affiliations: Department of Molecular & Integrative Physiology; Department of Bioengineering; Neuroscience Program; the Carle Illinois College of Medicine (CICOM); the Beckman Institute for Advanced Science and Technology (Intelligent Systems theme and the Neurotechnology for Memory and Cognition working group); the Carl R. Woese Institute for Genomic Biology (the Microbiome Metabolic Engineering theme); the Micro and Nanotechnology Laboratory; and the Roy J. Carver Biotechnology Center. Jonathan V. Sweedler Page 2 PROFESSIONAL EXPERIENCE UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN DIRECTOR, SCHOOL OF CHEMICAL SCIENCES (SCS) August 2012–present The School of Chemical Sciences consists of the Departments of Chemistry and Chemical and Biomolecular Engineering, and has a long tradition of excellence as one of the largest and highest ranked chemical research enterprises in the world. It has a combined annual budget in excess of 25 million dollars and has more than 200 employees. Duties of the Director include direct supervision and administration of the Departments of Chemistry and Chemical and Biomolecular Chemistry, reporting to the Dean of Liberal Arts and Sciences, and oversight of the school's space, safety, human resources, and its cluster of facilities. See http://www.scs.illinois.edu/. DIRECTOR, ROY J. CARVER BIOTECHNOLOGY CENTER (CBC) August 2002–August 2012 The CBC provides measurement services to the UIUC and outside communities in genomics, proteomics, metabolomics and a variety of other areas. Consisting of about 40 full-time staff, the CBC supports the research efforts of more than 280 research groups on the UIUC campus annually. Significant effort involved quadrupling the annual external funding; at the end of my tenure as director, the CBCs operating budget was >$10M/year, of which 56% derived from service revenue, 24% from campus subsidy, and 20% from off-campus sponsored funding. In 2011/2, $2M of new equipment was secured. As director, major duties also included strategic positioning of the center, the creation of new facilities, raising external funding, and a range of additional administrative duties. See: http://www.igb.illinois.edu/biotech/. DIRECTOR, UIUC NEUROPROTEOMICS & NEUROMETABOLOMICS CENTER ON CELL-CELL SIGNALING August 2004–present The UIUC Neuroproteomics & Neurometabolomics Center on Cell-Cell Signaling, a NIDA-funded P30 Center, both provides new proteomics and bioinformatics measurement capabilities to the UIUC and regional neuroscience community, and advances the performance of state-of-the-art proteomics technologies to new levels. The Center employs 10+ individuals working with multiple national and international research groups, and is involved in research, training and outreach activities. See: http://neuroproteomics.scs.illinois.edu NON-UNIVERSITY EDITOR-IN-CHIEF, ANALYTICAL CHEMISTRY American Chemical Society, Washington, D.C. December 2011–present Serving as the seventh Editor-in-Chief of Analytical Chemistry in its >90-year history; Analytical Chemistry, the highest impact and most cited journal in its field, has twenty associate editors, received ~6000 articles (published ~1800), and has a 6.3 impact factor in 2018. Responsibilities include an initial triage of manuscripts, assigning manuscripts to associate editors, writing editorials, making policy decisions, reviewing articles and promoting the journal. The editorials have been downloaded more than 200,000 times. EIC appointment renewed in 2016 for a second five-year term. EDITOR-IN-CHIEF, JOURNAL OF PROTEOME RESEARCH American Chemical Society, Washington, D.C. October 2015–March 2016 Served as the second and interim editor of the Journal of Proteome Research (JPR) during the search for the next full time editor. JPR had seven associate editors and received about 1000 articles in 2015. Jonathan V. Sweedler Page 3 SCIENTIFIC ADVISORY BOARDS Newomics Inc., Emeryville, CA December 2014–present Advanced Analytical Technologies, Ames, IA July 2007–May 2018 Evaluate new technologies and other developments related to these companies’ core analytical businesses. CO-FOUNDER, BOARD OF DIRECTORS AND VICE-PRESIDENT Magnetic Resonance Microsensors, Savoy, IL December 1994–2005 Company founded to commercialize a series of NMR microprobes designed for high-resolution nanoliter volume NMR with increased mass sensitivity. Co-wrote SBIR and STTR proposals funded to aid in the development of a series of static and on-line NMR probes. Company purchased in 2000 by Protasis Corporation, and offered a line of both flow and capillary LC-NMR probes. EDUCATION PHYSIOLOGY/MARINE SCIENCE EXPERIENCE University of Puerto Rico Summer 2001 Taught a section of the NSF-sponsored short course on tropical neuroethology. University of Illinois at Urbana-Champaign Spring 1999 Received a semester release time to learn additional invertebrate neurophysiology with Prof. Rhanor Gillette (Department of Molecular & Integrative Physiology) as advisor through the University’s “Second Discipline” program. Hopkins Marine Station, Stanford University Winter/Spring 1998 Worked with Prof. William Gilly to identify and study neuropeptides in cephalopods, as well as isolate and characterize several novel marine toxins and study their effects on ion channels. Audited two physiology/biophysics courses. Friday Harbor Marine Laboratory, University of Washington Summer 1997 Studied the functional and biochemical roles of several families of peptide hormones using opisthobranch mollusks as model systems. POSTDOCTORAL FELLOWSHIPS Stanford University February 1989–June 1991 Dr. Richard N. Zare, Dr. Richard H. Scheller, Advisors Postdoctoral Research: Increased the sensitivity of capillary zone electrophoresis (CZE) by improving optical detection methods. Engaged in fundamental studies of resolution and efficiency. Used CZE to assay the contents of bag cell neurons from Aplysia californica. Audited neurobiology and neurophysiology courses. Work resulted in three publications and 10 presentations. PH.D. ANALYTICAL CHEMISTRY University of Arizona August 1983–January 1989 Dr. M. Bonner Denton, Dissertation Director GPA 3.9/4.0 Dissertation Title: Development of New Holographic Interferometers and Array Detectors for Improved Spectrochemical Analysis. Jonathan V. Sweedler Page 4 Dissertation Research: Fundamental comparisons of signal-to-noise performance of solid state array detectors. Characterization of new array detectors for optical spectroscopy. Development of novel spectrographs including a two dimensional holographic spectrometer. Work resulted in 13 publications and 10 presentations. B.S. CHEMISTRY WITH HONORS University of California at Davis September 1979–June 1983 Undergraduate Research: Studied the imidazole-iron bond in iron porphyrin systems using high field (360 and 500 MHz) NMR spectroscopy. RESEARCH SCIENTIST Lawrence Livermore National Laboratory, CA June 1980–September 1982 Studied numerous methods to improve FT-IR analysis under the direct supervision of Dr. Tomas Hirschfeld, including an LC-IR interface. Work resulted in five presentations at national and international chemistry meetings. PROFESSIONAL MEMBERSHIPS American Association for the Advancement of Science (AAAS), Fellow American Chemical Society (ACS), Fellow American Society for Biochemistry and Molecular Biology (ASBMB) American Society for Pharmacology and Experimental Therapeutics (ASPET) Royal Society of Chemistry (RSC), Fellow Sigma Xi (Science Research Honor Society) Society for Neuroscience (SfN) Alpha Chi Sigma AWARDS AND FELLOWSHIPS University of Illinois: #1 on 2019 Top 100 Power List of Analytical Chemists, The Analytical Scientist 2019 CASSS Award for Outstanding Achievements in Separation Science 2019 Torbern Bergman Medal from the Swedish Chemical Society 2018 Visionary Award, American Diabetes Association 2018 A Top Ten Leader in Measurement Science, The Analytical Scientist 2017 ANACHEM Award, Federation of Analytical and Spectroscopy