This Diagram Was Automatically Generated by SRI International Pathway Tools Version 19.0, Authors S. Paley and P.D. Karp

This Diagram Was Automatically Generated by SRI International Pathway Tools Version 19.0, Authors S. Paley and P.D. Karp

Srs056259Cyc: SRS056259 Cellular Overview COFACTORS, PROSTHETIC GROUPS, ELECTRON CARRIERS BIOSYNTHESIS PENTOSE PHOSPHATE PATHWAYS FATTY ACIDS AND LIPIDS BIOSYNTHESIS 5,6- a β-D-glucan AMINO ACIDS DEGRADATION (S)-1- cytidine S-(2- a dextran dihydrothymine with a C3- dTTP trans- RESPIRATION tryptophan pyrroline-5- (S)-malate an oleoyl- a chlorophyll pheophytin b hydroxyacyl) adenosylcobalamin biosynthesis valine phenylalanine substituted dienelactone methanofuran biosynthesis respiration (anaerobic) degradation IX leucine proline isoleucine 4-hydroxyproline tyrosine carboxylate [acp] glucose glutathione I (early cobalt insertion) adenosylcobalamin biosynthesis biotin methylerythritol pantothenate and adenosylcobalamin pyridine nucleotide cycling (plants) superpathway of mycolate biosynthesis pentose phosphate glutamate degradation II degradation III uridine kinase: putative Nucleoside triphosphate ubiquinol-9 phosphate pathway superpathway chlorophyllide a ubiquinol-8 ubiquinol-7 ubiquinol-10 4-amino-2-methyl-5- 1,4-dihydroxy- thiamin coenzyme B/ pathway (partial) degradation I degradation degradation I degradation I degradation III dextranase O_49561_0 dihydropyrimidine pyrophosphohydrolase II (late cobalt incorporation) biosynthesis I superpathway coenzyme A biosynthesis I ubiquinol-6 salvage from cobinamide II superpathway of fatty degradation V (via STEROIDS DEGRADATION malate/L-lactate laminarinase: Chlorophyllase: Chlorophyllase: hydroxyacylglutathione carboxymethylenebutenolidase- biosynthesis of menaquinol- biosynthesis I biosynthesis biosynthesis biosynthesis phosphomethylpyrimidine 2-naphthoate diphosphate coenzyme M acyl-CoA precursor: carB protein: [+ 84 isozymes] dehydrogenase MazG: O_84600_1 8 biosynthesis I of ubiquinol-8 biosynthesis from regeneration acids biosynthesis (E. coli) 2-phospho- hydroxyglutarate) arginine O_55678_0 dehydrogenase: O_41258_0 O_71214_0 O_71214_0 hydrolase: O_14552_9 related protein: O_59031_0 (eukaryotic) (aerobic, light- dihydroxyacetone biosynthesis (eukaryotic) 4-hydroxybenzoate (eukaryotic) (eukaryotic) biosynthesis (yeast) biosynthesis I biosynthesis hydrolysis sitosterol O_65020_0 precursor: [+ 8 isozymes] uroporphyrinogen-III D-glyceraldehyde phosphoenol β-D-ribosylnicotinate acetyl-CoA D-glycerate D-ribulose trp trans-4- degradation O_19805_0 [+ 32 isozymes] pyruvate dependent) pyruvate phosphate (prokaryotic) 3-methyl-2- (eukaryotic) 5-phospho- II (Bacillus) a 2,3,4- leu ile IV (arginine val phe tyr degradation to CMP O_39892_0 a holo- uroporphyrinogen-III all-trans- 3-phosphate all-trans- all-trans- cobinamide 5-phosphate pro hydroxy- Biosynthetic (2S,5S)-5- a malonyl-[acp] chorismate oxobutanoate dihydromethanophenazine saturated androstenedione cholesterol a dextran [acyl-carrier oleate a β-D glucan a β-D glucan dTMP nonaprenyl (2E,6E)- chorismate all-trans- 4-hydroxybenzoate α-D-ribose 1- chorismate 4-amino-2-methyl-5- acetyl-CoA glt L-proline decarboxylase/ carboxymethyl a chlorophyllide phytol pheophorbide b phytol 2-maleylacetate 4-hydroxybenzoate uroporphyrinogen-III heptaprenyl 4-hydroxybenzoate decaprenyl Enolase (EC Aromatic amino acid degradation to fragment thymine a 2-hydroxy uroporphyrinogen-III diphosphate farnesyl 4-hydroxybenzoate hexaprenyl diphosphate diphosphate diphosphate diphosphomethylpyrimidine Biotin fatty agmatine aminotransferase proline oxaloacetate protein] glutathione 1-deoxy-D- 3-methyl-2-oxobutanoate acyl CoA 4.2.1.11): ribulose- deiminase androstenedione carboxylate C-methyltransferase: uroporphyrinogen-III C- diphosphate diphosphate Cob(I)alamin carboxyl branched-chain amino branched-chain branched-chain alpha (EC sitosterol O_63780_0 methyltransferase: O_63780_0 xylulose 5- isochorismate hydroxymethyltransferase chorismate- putative isochorismate synthase O_37300_0 phosphate Proline pathway) II (cholesterol chorismate adenosyltransferase carrier protein Biotin Palmitoyl- acid aminotransferase/ amino acid amino acid Aspartate/ 2.6.1.57) @ [+ 28 isozymes] 4-hydroxybenzoate phosphate synthase entC: Uroporphyrinogen superpathway of (EC 2.1.2.11): O_16569_4 -pyruvate 4-hydroxybenzoate 4-hydroxybenzoate amidophosphoribosyltransferase: entC: O_30595_9 Thiamin-phosphate carboxyl [+ 47 isozymes] 3-epimerase: NAD-specific dehydrogenase arg dehydrogenase) [+ 28 isozymes] polyprenyltransferase methanofuran octaprenyl- 4-hydroxybenzoate polyprenyltransferase polyprenyltransferase PduO (EC 2.5.1.17) F420H2- acetyl-CoA CoA lysine 4-amino-4- lysine aminotransferase/ aminotransferase/ tyrosine/aromatic Aspartate 2.6.1.1) synthase O_30595_9 decarboxylase (URO- demethylmenaquinol- [+ 23 isozymes] lyase: O_14552_20 [+ 12 isozymes] : O_17433_2 Nicotinate pyrophosphorylase heterodisulfide carboxylase: carrier protein O_30079_5 fermentation glutamate degradation II (EC 1.5.99.8) 3-beta a 6-(N-acetyl-D- superpathay (EC 2.5.1.39) biosynththesis diphosphate polyprenyltransferase (EC 2.5.1.39) (EC 2.5.1.39) dehydrogenase, docosahexanoate hydrolase N-formylkynurenine arginine, ornithine and proline interconversion deoxychorismate 4-amino-4- pyrroline- 4-amino-4- aminotransferase: : O_78604_0 cholesterol 5,6- [chondroitin]- cytidine (EC 2.2.1.7) [+ 12 isozymes] D): O_25697_1 8 biosynthesis O_8460_1 [+ 94 isozymes] [+ 45 isozymes] phosphoribosyltransferase (EC 2.5.1.3): O_793_4 reductase, iron- O_26835_3 acetyl-CoA [+ 44 isozymes] to acetate dehydrogenase (Proline deoxychorismate α-L- uridine an oxidized UTP a long- glucosaminyl)- of heme : O_45860_0 intermediate MF1 synthase: chorismate- asp (EC 2.5.1.39) : O_45860_0 : O_45860_0 beta subunit: biosynthesis II precursor phosphoenol (EC 1.4.1.2) lyase: O_26741_2 oxidase) / Delta- deoxychorismate hydroxy- O_79796_0 4-hydroxyphenylpyruvate[+ 65 isozymes] hydroxysteroid a ribonucleotide (S)-malate dihydrouracil a DsrEFH 4-O-sulfo-N- electron- propanoyl- 2’,3’-cyclic α-D-glucose precorrin-1 precorrin-1 a malonyl-[acp] : O_74958_0 [+ 9 isozymes] (EC 2.4.2.11): O_22672_0 [+ 51 isozymes] sulfur binding carboxylase: and butyrate lyase: O_26741_2 rhamnose linear glucan biosynthesis 4-hydroxybenzoate O_636_1 -pyruvate all-trans- : O_45860_0 4-hydroxybenzoate 4-hydroxybenzoate O_36272_0 [+ 97 isozymes] (EC 3.1.2.2) pyruvate [+ 53 isozymes] lyase: O_26741_2 carboxylate Biosynthetic arginine [+ 65 isozymes] dehydrogenase/ a perthiol acetylgalactosamine monophosphate 1-phosphatidyl- methyl ester [+ 88 isozymes] 2-dehydropantoate [+ 55 isozymes] O_26835_3 D-erythrose NADP-specific 1-pyrroline-5- complex transfer CoA from glutamate chorismate [+ 39 isozymes] lyase: octaprenyl 4-hydroxybenzoate isochorismate subunit, putative: : O_81723_0 D-xylulose [+ 53 isozymes] [+ 53 isozymes] isomerase: 3-beta uridine kinase: putative Nucleoside triphosphate 1D-myo-inositol polyprenyltransferase isochorismate 4-hydroxybenzoate polyprenyltransferase polyprenyltransferase 5-phospho-β- nicotinate β-nicotinate D-ribonucleotide putative F420H2- O_70597_0 [+ 97 isozymes] 5-phosphate 4-phosphate Kynurenine 1.4.1.4): lys carboxylate decarboxylase (EC 2-oxo-3- flavoprotein 2’,3’-cyclic nucleotide O_8460_1 diphosphate polyprenyltransferase adenosylcobinamide [+ 6 isozymes] 4.1.1.19): O_71470_0 O_20538_0 hydroxysteroid L-rhamnose O_49561_0 dihydropyrimidine Chondroitinase pyrophosphohydrolase 4-alpha- uroporphyrinogen-III (EC 2.5.1.39) 1-deoxy-D- coproporphyrinogen III Aspartate 1- (EC 2.5.1.39) (EC 2.5.1.39) D-ribosylamine dehydrogenase: [+ 37 isozymes] α-linolenate Transketolase, C- Transketolase, C- formamidase, lys O_73598_0 arg 4-methyl-2- 1.5.1.12): phenylpropanoate rNA ligase: malate/L-lactate 3’-phosphodiesterase n-acetylglucosaminylphosphatidylinositol uroporphyrinogen-III C- : O_30957_1 (EC 2.5.1.39) : O_30957_1 : O_30957_1 thiamin phosphate O_47857_0 malonyl-CoA pyruvate 3-methyl-2- 3-oxo- dehydrogenase/ mutarotase: [+ 84 isozymes] dehydrogenase (chondroitin lyase) MazG: O_84600_1 glucanotransferase [ C-methyltransferase: 3-oxoacyl- synthase, glt xylulose 5- all-trans- ketopantoate decarboxylase terminal section terminal section bacterial [+ 5 isozymes] oxopentanoate O_31386_0 (S)-3-methyl-2- [+ 52 isozymes] O_4902_3 O_30596_72 dehydrogenase: precursor: : O_12202_0 (EC 3.1.4.37) deacetylase: O_72858_1 methyltransferase: O_63780_0 methanofuran isochorismate : O_30957_1 2-succinyl-6-hydroxy- a 2,3,4- kinase: oxobutanoate 24-ethyl- isomerase: [+ 8 isozymes] (CBM20): O_8649_1 O_63780_0 KASIII (EC 2.3.1.180) phosphate 2-succinyl-6- octaprenyl reductase (EC 4.1.1.11) malonyl-CoA O_37925_0 (EC 2.2.1.1) (EC 2.2.1.1) (EC 3.5.1.9) [+ 5 isozymes] oxopentanoate O_19805_0 a reduced : O_40350_0 [+ 26 isozymes] synthase entC: 4-hydroxybenzoate UbiA 2,4-cyclohexadiene- adenosylcobinamide long-chain saturated Lysine cholest- O_20538_0 UMP O_39892_0 [DsrEFH [+ 63 isozymes] 6-(α-D- [+ 26 isozymes] : O_80260_0 hydroxy-2,4- Radical SAM family biosynththesis diphosphate PanE/ApbA: : O_5915_1 probable nicotinate- coenzyme A [+ 68 isozymes] : O_26568_0 : O_26568_0 : O_77701_1 [chondroitin]- electron- nonaprenyl-4- intermediate MF2 O_30595_9 prenyltransferase 3-heptaprenyl-4- 3-decaprenyl-4- 1-carboxylate amidohydrolase: Thiamine- Malonyl CoA- fatty acid-- fatty acid Lysine 2,3- Arginine ketoglutarate L-4- (4-hydroxyphenyl) 5-ene β-L- a thiol complex] acryloyl-CoA UMP glucosaminyl)- [+ 60 isozymes] cyclohexadiene- protein HutW, similar to O_26461_0 3-hexaprenyl-4- hydroxybenzoate hydroxybenzoate synthase: O_87900_4 nucleotide adenylyltransferase: [+ 106 isozymes] [+ 106 isozymes] 2-oxoglutarate (S)-1- agmatine a ribonucleotide N-acetyl- transfer cytidine 2’- acetate

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