9 January 2019 Drugs used in Diabetes (A10) Insulins and Analogues (A10A) 1. Insulin (human): a. Biphasic insulin b. Biphasic Isophane Human Insulin c. Human Regular Solution for Injection Insulin (I.M./S.C./I.V.); Solution d. Insulin human + 100 I.U./mL for Injection (S.C./I.V.); Isophane Insulin Solution for Injection Human (S.C.); Suspension for e. Neutral Insulin Human Injection (S.C.) + Isophane Insulin Human f. Recombinant Human Insulin 2. Insulin aspart a. Insulin aspart b. Biphasic Insulin Aspart c. Biphasic Insulin 100 Units/mL Solution for Injection (S.C.) Aspart 30 d. Biphasic Insulin Aspart 50 3. Insulin degludec 100 Units/mL Solution for Injection (S.C.) 4. Insulin degludec and Insulin 100 Units/mL (70% Insulin aspart Degludec/30% Insulin Solution for Injection (S.C.) Aspart) 5. Insulin degludec and 100 Units/3.6 mg per mL Solution for Injection (S.C.) Liraglutide 6. Insulin detemir 100 Units/mL Solution for Injection (S.C.) 7. Insulin glargine 100 Units/mL Solution for Injection (S.C.) 300 Units/mL 8. Insulin glargine and 3.64 mg (equivalent to 100 Lixisenatide Units of Insulin glargine/ 33 mcg per mL Solution) Solution for Injection (S.C.) 3.64 mg (equivalent to 100 Units of Insulin glargine/ 50 mcg per mL Solution) 9. Insulin glulisine 3.49 mg / mL (equivalent Solution for Injection (S.C.) to 100 units / mL) Solution for Injection (Subcutaneous/Continuous S.C. Pump Infusion/Intravenous) 10. Insulin lispro Solution for Injection a. rDNA origin (I.V./S.C./I.M.) b. 50% Insulin Lispro and 50% Insulin- Lispro-Protamine 100 Units/mL (3.5 mg/mL) Sulfate Suspension for Injection c. 25% Insulin Lispro (S.C.) and 75% Insulin- Lispro-Protamine Sulfate Blood Glucose Lowering Drugs, excluding Insulins (A10B) A. Biguanides (A10BA) 1. Metformin Tablet Film-Coated Tablet 500 mg Extended-Release Tablet Sustained-Release Capsule Oral Solution 750 mg Extended-Release Tablet Tablet Film-Coated Tablet 850 mg Extended-Release Tablet Oral Solution Tablet Film-Coated Tablet 1000 mg Extended-Release Tablet Sustained-Release Capsule Oral Solution B. Sulfonylureas (A10BB) 1. Glibenclamide 5 mg Tablet 2. Glipizide Tablet 2.5 mg Extended-Release Tablet Tablet 5 mg Extended-Release Tablet Controlled-Release Tablet Extended-Release Tablet 10 mg Controlled-Release Tablet 3. Gliclazide Modified-Release Tablet 30 mg Prolonged-Release Tablet 60 mg Modified-Release Tablet Tablet 80 mg Modified-Release Tablet 4. Glimepiride 1 mg 2 mg Tablet; Film-Coated Tablet 3 mg 4 mg C. Combinations of oral blood glucose lowering drugs (A10BD) 1. Metformin and Sulfonylureas a. Metformin and 500 mg + 5 mg Tablet Glipizide b. Metformin and 500 mg + 80 mg Film-Coated Tablet Gliclazide 850 mg + 80 mg c. Metformin and 500 mg + 1 mg Tablet Glimepiride Tablet Film-Coated Tablet 500 mg + 2 mg Sustained-Release Capsule Extended-Release Tablet Prolonged-Release Tablet 1 g + 2 mg Tablet d. Metformin and 250 mg + 1.25 mg Glibenclamide 500 mg + 2.5 mg Film-Coated Tablet 500 mg + 5 mg 500 mg + 5mg Tablet 1 g + 5 mg 2. Metformin and Pioglitazone 500 mg + 15 mg Film-Coated Tablet 850 mg +15 mg 3. Glimepiride and Pioglitazone 15 mg/2 mg Tablet 30 mg/2 mg 4. Metformin and Sitagliptin Tablet 50 mg + 500 mg Film-Coated Tablet 50 mg + 850 mg Tablet 50 mg + 1000 mg Tablet 50 mg + 1 g Film-Coated Tablet 100 mg + 1 g Extended-Release Tablet 5. Metformin and Vildagliptin 50 mg + 500 mg 50 mg + 850 mg Film-Coated Tablet 50 mg + 1000 mg 6. Pioglitazone and Alogliptin 12.5 mg/15 mg 12.5 mg/30 mg Film-Coated Tablet 25 mg/15 mg 25 mg/30 mg 7. Metformin and Saxagliptin 2.5 mg/1 g Film-Coated Tablet 5 mg/500 mg 5 mg/1 g 8. Metformin and Linagliptin 2.5 mg + 500 mg 2.5 mg + 850 mg Film-Coated Tablet 2.5 mg + 1000 mg 9. Metformin and Dapagliflozin 5 mg/500 mg 5 mg/1000 mg Tablet 10 mg/500 mg 10 mg/1000 mg 10. Linagliptin and 10 mg/5 mg Film-Coated Tablet Empagliflozin 25 mg/5 mg 11. Metformin and 5 mg/500 mg Empagliflozin 5 mg/850 mg 5 mg/1 g Film-Coated Tablet 12.5 mg/500 mg 12.5 mg/850 mg 12.5 mg/1 g 12. Pioglitazone, Metformin and 15 mg/500 mg/1 mg Film-Coated Tablet Glimepiride** 15 mg/500 mg/2 mg 13. Saxagliptin and 5 mg/10 mg Film-Coated Tablet Dapagliflozin D. Alpha glucosidase inhibitors (A10BF) Tablet 50 mg 1. Acarbose Film-Coated Tablet 100 mg Tablet Tablet 200 mcg Orally Disintegrating Tablet 2. Voglibose Tablet 300 mcg Dispersible Tablet E. Thiazolidinediones (A10BG) Tablet 15 mg Film-Coated Tablet 1. Pioglitazone 30 mg Tablet 45 mg Tablet F. Dipeptidyl peptidase 4 (DPP-4) inhibitors (A10BH) 1. Sitagliptin 25 mg 50 mg Film-Coated Tablet 100 mg 2. Vildagliptin 50 mg Tablet 2.5 mg 3. Saxagliptin Film-Coated Tablet 5 mg 4. Linagliptin 5 mg Tablet 5. Gemigliptin 50 mg Film-Coated Tablet 6. Sitagliptin and Simvastatin 100 mg + 10 mg Film-Coated Tablet 100 mg + 20 mg 100 mg + 40 mg G. Glucagon-like peptide-1 (GLP-1) analogues (A10BJ) Powder for Suspension for 2 mg Injection (S.C.) 250 mcg/mL (5 mcg/dose) 1. Exenatide Solution for Injection (S.C.) 250 mcg/mL (10 mcg/dose) 2. Liraglutide 6 mg/mL Solution for Injection (S.C.) 10 mcg + 0.2 mL (0.15 mg/3 mL) 3. Lixisenatide Solution for Injection (S.C.) 20 mcg + 0.2 mL H. Sodium-glucose co-transporter 2 (SGLT2) inhibitors (A10BK) 5 mg 1. Dapagliflozin Tablet 10 mg 100 mg 2. Canagliflozin Film-Coated Tablet 300 mg 10 mg 3. Empagliflozin Film-Coated Tablet 25 mg I. Other blood glucose lowering drugs, excluding insulins 500 mcg 1. Repaglinide 1 mg Tablet 2 mg 2. Nateglinide 120 mg Film-Coated Tablet .
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