Medications Sold in the United States that Can Cause Confirmed Positive Drug Test Results Medication Nonprescription Prescription Medications Medications (components or their metabolites) Amphetamines I–methamphetamine I–amphetamine and l-methamphetamine -amphetamine (Vicks Inhaler and Selegiline (Eldepryl and Ensam patch) is metabolized -methamphetamine generic equivalents) to l-methamphetamine and l-amphetamine l-amphetamine and d-amphetamine Adderall (approximately 3:1 mixture of d- to to l- amphetamine) d-amphetamine Dexedrine Paremyd ophthalmic (hydroxyampohetamine) is metabolized to d-amphetamine Procentra Vyvanase (lisdexamfetamine dimesylate) is metabolized to d-amphetamine d-amphetamine and d-methamphetamine Didrex (benzphetamine) is metabolized to d- methamphetamine and d-amphetamine Desoxyn contains d-methamphetamine. It is metabolized to d-amphetamine MDMA, MDA, MDEA None None Barbiturates -Butabarbital None Butisol -Butalbital None Ascomp with codeine Esgic and Esgic-Plus Fioricet Fiorinal Phrenilin Zebutal -Pentobarbital None Nembutal -Phenobarbital None Bellergal-S Donnatal Hysophen Mysoline (Primidone) is metabolized to phenobarbital Medication Nonprescription Prescription Medications Medications Benzodiazepines -Alprazolam None Niravan Xanax -Chlordiazepoxide None Librax Librium Limbitrol -Clonazepam None Klonopin -Clorazepate None Tranxene -Diazepam None Diastat Valium -Estazolam None available as generic -Temazepam None Restoril Cocaine None Cocaine hydrochloride, solution or viscous, used as a vasoconstrictive anesthetic, e.g., in otolaryngology, ophthalmology, and dentistry. TAC (tetracaine, adrenaline, and cocaine mixture). Used in some emergency rooms as a topical anesthetic, e.g., before suturing. Brompton’s Cocktail (contains an opiate - usually morphine – and cocaine and/or a phenothiazine); used in past years, rarely now, for pain control of the terminally ill. Marijuana None [Note: AK, CO, Dronabinol WA recently added.] Marinol Marijuana More than 20 states and the District of Columbia allow use of marijuana for certain medical conditions under a physician’s direction. These laws do not supersede DOT’s position that marijuana is not an acceptable medical explanation for a positive result. Methaqualone None None Medication Nonprescription Prescription Medications Medications Opioids: -Buprenorphine None Burprenex Butrans Suboxone Zubsolv -Codeine Several states allow Cheratussin with codeine over-the-counter Synalgos sales of codeine- Many drugs are sold in combination with codeine as containing cough stated in their names, e.g., Promethazine with medicines codeine, Tylenol with codeine etc. -Fentanyl None Abstral Actiq Duragesic Fentora Lazanda Onsolis Subsys Hydrocodone None Co-Gesic Hycet Hydromet Lorcet Lortab Norco Reprexain Rezira TussiCaps Tussigon Tussionex Vicodin Vicoprofen Zutripro Zydone -Hydromorphone None Dilaudid Exalgo Hydromorphone can also be produced by large amounts of morphine through a minor metabolic pathway -Meperidine None Demerol Medication Nonprescription Prescription Medications Medications Methadone None Dolophine Methadose -Morphine Donnagel-PG Apokyn Infantol Pink Astramorph Kaodene with Avinza paregoric Brompton’s Cocktail (see “Cocaine” above) Quiagel PG DepoDur Duramorph Embeda Infumorph Kadian MS Contin -Oxycodone None Endocet Endodan Oxecta Oxycontin Percocet Percodan Roxicet Roxicodone Roxilox Tylox -Oxymorphone None Opana -Propoxyphene None Propoxyphene-containing medications were removed from the U.S. market in November 2010 Robert B. Swotinsky. The Medical Review Officer’s Manual, 5th Edition, 2015, Exhibit 11-3, pp 151-152. With permission from MROCC. .