S720 14th International Congress of Endocrinology Sat. March 27 Scientific Program Plenary Lectures Room 1 PL1 8:25 - 9:10 Chairperson: Kenji Kangawa National Cardiovascular Center Research Institute, Osaka, Japan Bowels control brain - gut hormones and obesity Stephen R. Bloom Imperial College London, UK PL2 16:10 - 16:55 Chairperson: Hajime Nawata Fukuoka Prefectural University, Fukuoka, Japan Insulin signaling molecules and pathogenesis of type 2 diabetes mellitus Masato Kasuga Research Institute, International Medical Center of Japan PL3 16:55 - 17:40 Chairperson: Toshio Matsumoto Department of Medicine and Bioregulatory Sciences, University of Tokushima Graduate School of Medical Sciences, Japan Parathyroid hormone’s actions on bone Henry M. Kronenberg Massachusetts General Hospital, USA Meet-the-Professor 11:10-12:00 MTP1 Management of diabetes and cardiovascular protection Room 2 Chairpersons: Rury R. Holman Diabetes Trials Unit, The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK Peter Gaede Steno Diabetes Center, Denmark MTP1-1 Management of diabetic nephropathy Ryuichi Kikkawa Shiga University of Medical Science, Otsu, Japan MTP1-2 Management of diabetes and cardiovascular protection Rury R. Holman Diabetes Trials Unit, The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK MTP2 Primary aldosteronism Room 3 Chairpersons: Franco Mantero Department of Medical and Surgical Sciences, University of Padua, Italy Ching-Chung Chang The Endocrine Society of the Republic of China, Taiwan MTP2-1 Current issues on the diagnosis and treatment of primary aldosteronism Sadayoshi Ito Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine, Tohoku University School of Medicine, Sendai, Japan MTP2-2 Primary aldosteronism Franco Mantero Endocrinology Unit, Department of Medical and Surgical Sciences, University of Padua, Italy MTP3 * GH and IGF-1 deficiency Room 4 Chairpersons: Ron G. Rosenfeld Department of Pediatrics, Oregon Health & Science University, USA Kazuo Chihara Hyogo Prefectural Kakogawa Medical Center, Japan MTP3-1 Novel syndrome of growth hormone deficiency: adult combined GH, PRL and TSH deficiency associated with circulating anti-PIT-1 antibody Yutaka Takahashi Department of Internal Medicine, Division of Diabetes, Metabolism and Endocrinology, Kobe University Graduate School of Medicine, Kobe, Japan MTP3-2 Diagnosis and management of IGF deficiency Ron G. Rosenfeld Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, USA MTP4 * Estrogen action and disease Room 5 Chairpersons: Evan R. Simpson Prince Henry’s Institute of Medical Research, Australia Hideo Honjo Aiseikai Yamashina Hospital, Kyoto, Japan MTP4-1 Genetic Mutations of CYP19A1 in humans Makio Shozu Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Japan MTP4-2 The link between the LKB1/AMPK pathway and aromatase in the breast provides a link between obesity and breast cancer Evan R. Simpson Prince Henry’s Institute of Medical Research, Australia Scientific Program Sat. March 27 S721 MTP5 * Obesity and hypothalamo-pituitary axis Room 6 Chairpersons: Felipe F. Casanueva Department of Medicine, University of Santiago de Compostela, Santiago de Compostela University Hospital Complex, Spain Shigeru Matsukura Chiyoda Hospital, Miyazaki, Japan MTP5-1 Obesity and central regulation of appetite Masamitsu Nakazato Department of Internal Medicine, Division of Neurology, Respirology, Endocrinology and Metabolism, University of Miyazaki, Miyazaki, Japan MTP5-2 Obesity and hypothalamo-pituitary axis Felipe F. Casanueva Department of Medicine, University of Santiago de Compostela, Santiago de Compostela University Hospital Complex, Spain MTP6 Graves’ disease Room 7 Chairpersons: Valeria Guimaraes Physician-Clinical Practitioner, ENNE, Brazil Toru Mori Higashiyamatakeda Hospital, Kyoto, Japan MTP6-1 Antithyroid drug therapy of Graves’ disease: Methimazole or propylthiouracil and how much of the dosage? Hirotoshi Nakamura Department of Internal Medicine II, Hamamatsu University School of Medicine, Hamamatsu, Japan MTP6-2 TBD Terry F. Davies Mount Sinai School of Medicine, USA MTP7 Andropause Room 8 Chairpersons: Ilpo T. Huhtaniemi Department of Surgery and Cancer, Division of Cancer, Reproductive Biology, Clinical Obstetrics and Gynaecology, Imperial College London, London, UK Gianni Forti Endocrine Unit, Department of Physiopathology, University of Florence, Italy MTP7-1 Effects of testosterone replacement therapy for late-onset hypogonadism patients mainly suffering from psychological symptoms Tadashi Matsuda Department of Urology and Andrology, Kansai Medical University, Hirakata, Japan MTP7-2 Andropause - Fact or fiction? Ilpo T. Huhtaniemi Department of Surgery and Cancer, Division of Cancer, Reproductive Biology, Clinical Obstetrics and Gynaecology, Imperial College London, London, UK MTP8 Cardiac natriuretic peptides Room 9 Chairpersons: M. Gary Nicholls Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand Yoshihiko Saito First Department of Internal Medicine, Nara Medical University, Japan MTP8-1 Positioning of rapid BNP assay in the emergency room and intensive care unit Michihiro Yoshimura The Jikei University School of Medicine, Tokyo, Japan MTP8-2 Cardiac natriuretic peptides: Looking to the future M. Gary Nicholls Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand MTP9 * FGF family and disease Room 10 Chairpersons: Kenneth E. White Indiana University School of Medicine, USA Yasuo Imanishi Osaka City University Graduate School of Medicine, Osaka, Japan MTP9-1 Evolution and functional diversity of the Fgf gene family Nobuyuki Itoh Kyoto University Graduate School of Pharmaceutical Sciences, Kyoto, Japan Sat. March 27 MTP9-2 Fibroblast growth factor-23 (FGF23) Kenneth E. White Indiana University School of Medicine, USA MTP10 Diabetes insipidus Room 15 Chairpersons: Soren Rittig Pediatric Research Center, Department of Pediatrics, Aarhus University Hospital, Denmark San-e Ishikawa Department of Medicine, Jichi Medical University Saitama Medical Center, Saitama, Japan MTP10-1 Subclinical diabetes insipidus Yasumasa Iwasaki Health Care Center, Kochi University, Kochi, Japan MTP10-2 Diabetes insipidus - Translational aspects Soren Rittig Pediatric Research Center Skejby, Department of Pediatrics, Aarhus University Hospital, Denmark * Basic/TR S722 14th International Congress of Endocrinology Symposia 9:20-11:00 SY1-1 Molecular basis for insulin resistance and diabetes Room 2 Chairpersons: Morris F. White Howard Hughes Medical Institute, Division of Endocrinology, Children’s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA Wataru Ogawa Kobe University Graduate School of Medicine, Japan SY 1-1-1 * Mechanism of insulin resistance and the rational path to a cure Morris F. White Howard Hughes Medical Institute, Division of Endocrinology, Children’s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA SY 1-1-2 Regulation of insulin action and secretion by SOCS proteins and microRNAs Emmanuel Van Obberghen Department of Biochemistry and Molecular Biology, and INSERM Unit 907, Faculty of Medicine, University of Nice Sophia Antipolis; SY 1-1-3 Transcriptional regulation of hepatic energy metabolism Wataru Ogawa Kobe University Graduate School of Medicine, Japan SY 1-1-4 Role of liver transcription ChREBP in the the development of hepatic steatosis in mouse and human liver Catherine Postic Departement of Endocrinology, Metabolism and Cancer, Cochin Institute, Inserm U1016, France SY1-3 Regulation of pancreatic beta cell mass Room 5 Chairpersons: Rohit N. Kulkarni Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA Yasuo Terauchi Department of Endocrinology and Metabolism, Yokohama City University, Yokohama, Japan SY 1-3-1 * Growth factor signaling in the regulation of ER stress and pancreatic beta cell mass Rohit N. Kulkarni Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA SY 1-3-2 Regulation of pancreatic beta cell mass Harry Heimberg Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium SY 1-3-3 Role of glucokinase on pancreatic beta-cell mass and impact of glucokinase activator on the regulation of beta-cell mass Yasuo Terauchi Department of Endocrinology and Metabolism, Yokohama City University, Yokohama, Japan SY 1-3-4 Role of autophagy in the regulation of pancreatic β-cell mass and function Hye S. Jung Seoul National University Hospital, Republic of Korea SY1-7 Diabetic complications Room 10 Chairpersons: George L. King Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA Masakazu Haneda Department of Medicine, Asahikawa Medical College, Asahikawa, Japan SY 1-7-1 * Diabetic complications- Mechanisms beyond oxidative stress George L. King Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA SY 1-7-2 Canceled SY 1-7-3 Pathogenic role of mitochondrial reactive oxygen species in diabetes and its complications Takeshi Nishikawa Department of Metabolic Medicine, Kumamoto University, Kumamoto, Japan SY 1-7-4 Pathogenesis of diabetic nephropathy: Role of hypoxia-inducible factor-1α (HIF-1α) Masakazu Haneda Department of Medicine, Asahikawa Medical College, Asahikawa, Japan SY3-4 Peptide networks in energy metabolism Room 6 Chairpersons: Yukari Date Frontier Science Research Center, University of Miyazaki, Japan Kevin L. Grove Division of Neuroscience, Oregon