Known Bioactives Library: Biomol ICCBL - 2012

Known Bioactives Library: Biomol ICCBL - 2012

Known Bioactives Library: Biomol ICCBL - 2012 ICCB-L ICCB-L Vendor Vendor ID Compound Name Compound description Plate Well 3402 A03 Enzo Life Sciences SL-115 C16 Ceramide Bioactive lipids: Activates PKC zeta 3402 A04 Enzo Life Sciences L-120 C-PAF Bioactive lipids: PAF receptor agonist 3402 A05 Enzo Life Sciences SL-145 C8 Ceramine Bioactive lipids: Ceramide analog. Apoptosis inducer 3402 A06 Enzo Life Sciences PG-047 D12-Prostaglandin J2 Bioactive lipids: Bioactive prostaglandin 3402 A07 Enzo Life Sciences FA-021 (R)-(+)-Methandamide CNS receptor ligands: Cannabinoid CB1 receptor agonist 3402 A08 Enzo Life Sciences FA-009 Dihomo-gamma-linolenic acid Bioactive lipids: Polyunsaturated fatty acid 3402 A09 Enzo Life Sciences DM-200 1α,25-Dihydroxyvitamin D3 Nuclear receptor ligands: Vitamin D receptor agonist 3402 A10 Enzo Life Sciences SL-125 Dihydrosphingosine Bioactive lipids: Apoptosis inducer 3402 A11 Enzo Life Sciences DG-100 1,2-Didecanoyl-glycerol (10:0) Bioactive lipids: Activates PKC 3402 A12 Enzo Life Sciences GR-207 Diidolylmethane Nuclear receptor ligands: AHR agonist 3402 A13 Enzo Life Sciences DG-112 1,2-Dioctanoyl-SN-glycerol Bioactive lipids: Activates PKC 3402 A14 Enzo Life Sciences SL-205 DL-Dihydrosphingosine Lipid biosynthesis: Sphingosine kinase inhibitor 3402 A15 Enzo Life Sciences DG-115 1,2-Dioleoyl-glycerol (18:1) Bioactive lipids: Activates PKC 3402 A16 Enzo Life Sciences SL-210 DL-PDMP Lipid biosynthesis: Glucosylceramide synthase inhibitor 3402 A17 Enzo Life Sciences EE-11 (±)11(12)-Epoxyeicosatrienoic acid Bioactive lipids: Bioactive arachidonic acid metabolite 3402 A18 Enzo Life Sciences SL-215 DL-PPMP Lipid biosynthesis: Glucosylceramide synthase inhibitor 3402 A19 Enzo Life Sciences H-112 12(R)-HETE Bioactive lipids: Bioactive arachidonic acid metabolite 3402 A20 Enzo Life Sciences FA-002 Docosahexaenoic acid(22:6 n-3) Bioactive lipids: Polyunsaturated fatty acid 3402 A21 Enzo Life Sciences H-012 12(S)-HETE Bioactive lipids: Bioactive arachidonic acid metabolite 3402 A22 Enzo Life Sciences FA-012 Docosapentaenoic acid Bioactive lipids: Polyunsaturated fatty acid 3402 B03 Enzo Life Sciences AC-104 Bepridil·HCl Ion channel ligands: Calcium channels 3402 B04 Enzo Life Sciences GR-313 Lycorine Inhibitors: inhibits TNFalpha production 3402 B05 Enzo Life Sciences CA-415 Cyclopiazonic acid Ion channel ligands: Intracellular calcium 3402 B06 Enzo Life Sciences GR-316 10-hydroxycamptothecin Inhibitors: topoisomerase 1 inhibitor 3402 B07 Enzo Life Sciences AC-100 Dantrolene Ion channel ligands: Intracellular calcium 3402 B08 Enzo Life Sciences GR-308 Beta-lapachone Inhibitors: topoisomerase 1 inhibitor 3402 B09 Enzo Life Sciences KC-115 Diazoxide Ion channel ligands: Potassium channels 3402 B10 Enzo Life Sciences T-113 Parthenolide Inhibitors: IkappaB kinase inhibitor 3402 B11 Enzo Life Sciences CA-204 Dichlorobenzamil·HCl Ion channel ligands: Calcium channels 3402 B12 Enzo Life Sciences PI-102 MG-132 Protease inhibitors: Proteasome inhibitor 3402 B13 Enzo Life Sciences CA-205 Diltiazem·HCl Ion channel ligands: Calcium channels 3402 B14 Enzo Life Sciences EI-352 QNZ Inhibitors: NFkappaB inhibitor 3402 B15 Enzo Life Sciences KC-158 E-4031 Ion channel ligands: Potassium channels 3402 B16 Enzo Life Sciences GR-211 bezafibrate Nuclear receptor ligands: PPAR alpha agonist 3402 B17 Enzo Life Sciences CM-102 Fipronil Ion channel ligands: Misc. channels 3402 B18 Enzo Life Sciences IM-100 Cycloheximide-N-ethylethanoate Inhibitors: FKBP12 inhibitor 3402 B19 Enzo Life Sciences AC-130 Flecainide acetate Ion channel ligands: Sodium channels 3402 B20 Enzo Life Sciences A-165 Ascomycin (FK-520) Inhibitors: binds to FKBP inhibits calcineurin 3402 B21 Enzo Life Sciences AC-123 Flufenamic acid Ion channel ligands: Potassium channels 3402 B22 Enzo Life Sciences FR-100 U-74389G Inhibitors: superoxide/free-radical inhibitor 3402 C03 Enzo Life Sciences HP-012 12(S)-HPETE Bioactive lipids: Fatty acid hydroperoxide 3402 C04 Enzo Life Sciences FA-010 Docosatrienoic acid (22:3 n-3) Bioactive lipids: Polyunsaturated fatty acid 3402 C05 Enzo Life Sciences G-234 12-Methoxydodecanoic acid Bioactive lipids: Myristic acid analog 3402 C06 Enzo Life Sciences FA-024 Eicosa-5,8-dienoic acid (20:2 n-12) Bioactive lipids: Polyunsaturated fatty acid 3402 C07 Enzo Life Sciences HO-013 13(S)-HODE Bioactive lipids: Bioactive linoleic acid metabolite 3402 C08 Enzo Life Sciences FA-007 Eicosadienoic acid (20:2 n-6) Bioactive lipids: Polyunsaturated fatty acid 3402 C09 Enzo Life Sciences HP-013 13(S)-HPODE Bioactive lipids: Fatty acid hydroperoxide 3402 C10 Enzo Life Sciences FA-001 Eicosapentaenoic acid (20:5 n-3) Bioactive lipids: Polyunsaturated fatty acid 3402 C11 Enzo Life Sciences PG-048 13,14-Dihydro-PGE1 Bioactive lipids: Bioactive prostaglandin 3402 C12 Enzo Life Sciences FA-008 Eicosatrienoic acid (20:3 n-3) Bioactive lipids: Polyunsaturated fatty acid 3402 C13 Enzo Life Sciences GR-102 13-cis retinoic acid Nuclear receptor ligands: Retinoid receptor ligand 3402 C14 Enzo Life Sciences L-110 Enantio-PAF C16 Bioactive lipids: Negative control for PAF 13-Keto-octadeca-9Z,11E-dienoic 3402 C15 Enzo Life Sciences KO-013 Bioactive lipids: Bioactive linoleic acid metabolite acid 3402 C16 Enzo Life Sciences G-222 Farnesylthioacetic acid Bioactive lipids: Carboxymethylation inhibitor (±)14,15-Epoxyeicosa-5Z,8Z,11Z- 3402 C17 Enzo Life Sciences EE-14 Bioactive lipids: Bioactive arachidonic acid metabolite trienoic acid 3402 C18 Enzo Life Sciences RA-105 Fluprostenol Bioactive lipids: Prostaglandin FP receptor agonist 3402 C19 Enzo Life Sciences H-015 15(S)-HETE Bioactive lipids: Bioactive arachidonic acid metabolite 3402 C20 Enzo Life Sciences FA-006 Gamma-linolenic acid (18:3 n-6) Bioactive lipids: Polyunsaturated fatty acid 3402 C21 Enzo Life Sciences HP-015 15(S)-HPETE Bioactive lipids: Fatty acid hydroperoxide 3402 C22 Enzo Life Sciences LE-009 Leukotoxin A (9,10-EODE) Bioactive lipids: Bioactive linoleic acid metabolite 3402 D03 Enzo Life Sciences CA-225 Flunarizine·2HCl Ion channel ligands: Calcium channels 3402 D04 Enzo Life Sciences EI-207 Ebselen Inhibitors: glutathione peroxidase mimetic 3402 D05 Enzo Life Sciences AC-116 Fluspirilene Ion channel ligands: Potassium channels 3402 D06 Enzo Life Sciences CN-266 TRIM Inhibitors: bNOS/iNOS inhibitor 3402 D07 Enzo Life Sciences CA-245 FPL-64176 Ion channel ligands: Calcium channels 3402 D08 Enzo Life Sciences PD-195 Zardaverine Inhibitors: phosphodiesterase (PDE1/2) inhibitor 3402 D09 Enzo Life Sciences CA-422 6-Gingerol Ion channel ligands: Intracellular calcium 3402 D10 Enzo Life Sciences PD-190 Zaprinast Inhibitors: phosphodiesterase (PDE1) inhibitor 3402 D11 Enzo Life Sciences AC-120 Glipizide Ion channel ligands: Potassium channels 3402 D12 Enzo Life Sciences PD-185 Vinpocetine Inhibitors: phosphodiesterase (PDE1) inhibitor 3402 D13 Enzo Life Sciences KC-120 Glyburide Ion channel ligands: Potassium channels 3402 D14 Enzo Life Sciences PD-180 Trequinsin Inhibitors: phosphodiesterase (PDE3) inhibitor 3402 D15 Enzo Life Sciences NA-135 Grayanotoxin III Ion channel ligands: Sodium channels 3402 D16 Enzo Life Sciences PD-179 Siguazodan Inhibitors: phosphodiesterase (PDE3) inhibitor 3402 D17 Enzo Life Sciences CM-101 R(+)-IAA-94 Ion channel ligands: Misc. channels 3402 D18 Enzo Life Sciences PD-175 Rolipram Inhibitors: phosphodiesterase (PDE4 ) inhibitor 3402 D19 Enzo Life Sciences CA-207 L-cis-Diltiazem·HCl Ion channel ligands: Calcium channels Biomol ICCBL - 2012 Page 1 of 6 Created 9/2015 ICCB-L ICCB-L Vendor Vendor ID Compound Name Compound description Plate Well 3402 D20 Enzo Life Sciences EI-117 Ro 20-1724 Inhibitors: phosphodiesterase (PDE4 ) inhibitor 3402 D21 Enzo Life Sciences AC-128 Lidocaine·HCl·H2O Ion channel ligands: Sodium channels 3402 D22 Enzo Life Sciences PD-155 MY-5445 Inhibitors: phosphodiesterase (PDE5) inhibitor 3402 E03 Enzo Life Sciences PG-050 15-deoxy-Prostaglandin J2 Bioactive lipids: Bioactive prostaglandin 3402 E04 Enzo Life Sciences LE-012 Leukotoxin B (12,13-EODE) Bioactive lipids: Bioactive linoleic acid metabolite 3402 E05 Enzo Life Sciences K-015 15-Ketoicosatetraenoic acid Bioactive lipids: Bioactive arachidonic acid metabolite 3402 E06 Enzo Life Sciences LB-004 Leukotriene B4 Bioactive lipids: Leukotriene B4 receptor agonist 3402 E07 Enzo Life Sciences PG-021 16,16-Dimethyl-prostaglandin E2 Bioactive lipids: Prostaglandin EP receptor agonist 3402 E08 Enzo Life Sciences LC-004 Leukotriene C4 Bioactive lipids: CysLT receptor agonist 3402 E09 Enzo Life Sciences EI-103 17-Octadecynoic acid Lipid biosynthesis: Inhibits fatty acid omega oxidation 3402 E10 Enzo Life Sciences LD-004 Leukotriene D4 Bioactive lipids: CysLT receptor agonist 3402 E11 Enzo Life Sciences PG-042 17-Phenyl-trinor-prostaglandin E2 Bioactive lipids: Prostaglandin EP1 receptor agonist 3402 E12 Enzo Life Sciences LE-004 Leukotriene E4 Bioactive lipids: CysLT1 receptor agonist 3402 E13 Enzo Life Sciences L-134 1-Acyl-PAF Bioactive lipids: PAF agonist 3402 E14 Enzo Life Sciences FA-023 Linoleamide Endocannabinoids: Bioactive linoleic acid metabolite 1-Hexadecyl-2-arachidonoyl- 3402 E15 Enzo Life Sciences DG-140 Bioactive lipids: DAG analog glycerol 3402 E16 Enzo Life Sciences FA-014 Linoleic acid Bioactive lipids: Polyunsaturated fatty acid 3402 E17 Enzo Life Sciences L-106 1-Hexadecyl-2-methylglycero-3 PC Bioactive lipids: PAF receptor agonist 3402 E18 Enzo Life Sciences FA-005 Linolenic acid (18:3 n-3) Bioactive lipids: Polyunsaturated fatty acid 3402 E19 Enzo Life Sciences EI-150 1-Hexadecyl-2-O-acetyl-glycerol

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