New Projects at EMBL Approved in 2004 Protein Crystallography PX-03-366 Structure determination of laccase from Panus Mangani Siena Tigrinus PX-03-404 Tetracycline repressor with tetracycline analogs Hinrichs Greifswald PX-03-405 GsiB from Bsu Hinrichs Greifswald PX-03-406 mtDBP DNA binding protein Sixma Amsterdam PX-03-407 Mariner Transposase Walkinshaw Edinburgh PX-03-408 Structure analysis of the complex of BMP-2 and Mueller Würzburg the inhibitory protein Chordin PX-03-409 Human Complement Factor H Domains 18-20 Goldman Helsinki PX-03-410 SeMet MltA mutant complex Dijkstra Groningen PX-03-411 Argonaute protein from Pyroccocus Furiosus Barford London PX-03-412 Collagen triple helix mimics Berisio Napoli PX-03-413 Structure of a polysaccharide deacetylase from Kokkinidis Heraklion Bacillus cereus PX-03-414 Phosphoribosyl isomerase (PriA) Fulop Coventry PX-03-415 Structure determination of a small GTPase Rudolph Göttingen PX-03-416 Crystal structure of a microbial beta-Xylosidase Schomburg Köln PX-03-417 Substrate recognition by lytic transglycosylase Dijkstra Groningen MltA PX-03-418 Structure and mechanism of HNL from flax Kratky Graz (Linum usitatissimum) PX-03-419 Synthetic peptides which form a leucine zipper Höhne Berlin PX-03-420 Structural analysis of NRPS Te-domains Essen Marburg PX-03-421 ATCases from extremophiles in complex with Beeumen Ghent effectors and inhibitors PX-03-422 Putative GST transferase from Shewanella Beeumen Ghent Oneidensis PX-03-423 Structural studies of glutathione amide reductase Beeumen Ghent in complex with substrates and inhibitors PX-03-424 Structure-function relationships of xylanases Beeumen Ghent from extremophiles at ultrahigh resolution PX-03-425 The crystal structure of the exchange factor EF- Berisio Napoli 1beta isolated from Sulfolobus solfataricus PX-04-001 Alpha-L-fucosidase from Sulfolobus sulfataricus Bolognesi Genova PX-04-002 GDP-D-mannose dehydratase from Paramecium Bolognesi Genova bursaria chlorella virus - 1 (PBCV-1) PX-04-003 Acylphosphatases from mesophiles and Bolognesi Genova extremophiles PX-04-004 Slow structural changes of Pterocarpus Wyns Brussels angolensis lectin upon demetallization: a time- resolved study PX-04-005 Structural and functional consequences of Wyns Brussels remetallization of metal-free Ptreocarpus angolensis lectin PX-04-006 Plasmid addiction and programmed bacterial cell Wyns Brussels death PX-04-007 Bacterial fimbrial adhesins Wyns Brussels PX-04-008 Carbohydrate recognition by plant lectins Wyns Brussels PX-04-009 Microbial nucleoside hydrolases Wyns Brussels PX-04-010 VHH antibody fragments from camels Wyns Brussels PX-04-011 Structural studies of bacterial type II secretion Wyns Brussels systems PX-04-012 Crystal Structure of Aminopeptidase FrvX from Baumann Bern P. horikoshii PX-04-013 Argonaute protein from Pyroccocus Furiosus Barford London PX-04-014 Structure determination of a transient complex of Leys Leicester redox partners: human ETF:MCAD PX-04-015 Structure determination of a transient complex of Leys Leicester redox partners: [TMADH-ETF] PX-04-016 Atomic structure of aromatic amine Leys Leicester dehydrogenase: a time-resolved study PX-04-017 Dimethylglycine oxidase: investigating Leys Leicester channelling and the disease non-ketotic hyperglycinemia PX-04-018 Mechanism of aminomethyltransferase: structure Leys Leicester of the E.coli T-protein:H-protein complex PX-04-019 Structure determination of the SHP:DHC Leys Leicester complex: a novel bacterial respiratory system PX-04-020 Atomic resolution studies of a mycobacterial Leys Leicester P450 PX-04-021 Structure of a thermophilic DNA-lyase Leys Leicester PX-04-022 Structure of the human DMGDH-ETF complex Leys Leicester PX-04-023 Structure determination of a DNA-binding Leys Leicester protein involved in regulating halorespiration PX-04-024 Structure determination of a novel thermophilic Leys Leicester proline dehydrogenase PX-04-025 Crystal structure of RdmE Schneider Stockholm PX-04-026 Structure of DHPY Schneider Stockholm PX-04-027 Structure of OCDC Schneider Stockholm PX-04-028 Phosphoserine aminotransferase from Papageorgiou Turku alkaliphilic sources PX-04-029 Dpr Papageorgiou Turku PX-04-030 PHB Depolymerase (PhaZ7) Papageorgiou Turku PX-04-031 Asparaginase Papageorgiou Turku PX-04-032 Structural studies of protein translocation Kuehlbrandt Frankfurt am Main PX-04-033 Crystallisation of the Noradrenaline transporter Kuehlbrandt Frankfurt am from M. jannasschii Main PX-04-034 X-ray crystallographic studies of tranlation Song Singapore termination factor RF3 from E. coli PX-04-035 X-ray crystallographic studies of RNA helicase Song Singapore protein hUpf1p PX-04-036 Structural studies on human mitochondrial Wierenga Oulu enoyl-CoA isomerase PX-04-037 Structural studies on peptide binding domain of Wierenga Oulu human collagen prolyl 4-hydroxylase PX-04-038 16-mer from hammerhead rybozyme Rypniewski Poznan PX-04-039 Taxol structure Rypniewski Poznan PX-04-040 Crystallographic studies of cytokinin-specific Jaskolski Poznan binding proteins (CSBP) PX-04-041 Crystallographic studies of LlPR10 proteins, Jaskolski Poznan second sublass PX-04-042 Structure-function studies of wild type and Wierenga Oulu mutant bacterial and human thiolases PX-04-043 Structural studies on MFE-1 Wierenga Oulu PX-04-044 SAD-phasing of a highly twinned GTPase Rudolph Göttingen crystal using strontium PX-04-045 CPDA2 Blankenfeldt Dortmund PX-04-046 Structural studies of RNA helicases Rudolph Göttingen PX-04-047 Test data collection for different protein crystals Betzel Hamburg (in term of a student course) PX-04-048 Structure of ML 1 and 3 and complexes with Betzel Hamburg target molecules PX-04-049 Laccase from Melanocarpus albomyces Rouvinen Joensuu PX-04-050 Xylanase IV from Trichoderma reesei Rouvinen Joensuu PX-04-051 ENA Fab-fragments Rouvinen Joensuu PX-04-052 Glucose/Xylose isomerase Rouvinen Joensuu PX-04-053 Hydrophobin Rouvinen Joensuu PX-04-054 M1 Fab-fragment Rouvinen Joensuu PX-04-055 Structural studies of Dcps, a scavenger Song Singapore decapping enzyme im mRNA turnover PX-04-056 DHFR from thermophilic bacteria and structural Betzel Hamburg influence towards thermostability PX-04-057 Glutathione S-transferases from helminths Betzel Hamburg PX-04-058 High resolution structural analysis of PLA2s and Betzel Hamburg inhibitor complexes PX-04-059 Oxidized form of human peroxiredoxin 5 Declercq Louvain-la-Neuve PX-04-060 Structure of human peroxiredoxin 4 Declercq Louvain-la-Neuve PX-04-061 Structure of human peroxiredoxin 3 Declercq Louvain-la-Neuve PX-04-062 Structure of human thioredoxin 2 Declercq Louvain-la-Neuve PX-04-063 Structural studies of fatty acyl CoA thioesterases Wierenga Oulu PX-04-064 Structural studies of Alpha-methylacyl-CoA Wierenga Oulu racemase PX-04-065 Microgravity grown crystals Declercq Louvain-la-Neuve PX-04-066 Complexes of apoferritin Declercq Louvain-la-Neuve PX-04-067 Selected mutants of beta-lactamase Declercq Louvain-la-Neuve PX-04-068 Structure of S-layer proteins Declercq Louvain-la-Neuve PX-04-069 C-terminal Binding Protein 3/Brefeldin A ADP Bolognesi Genova Ribosylated Substrate CtBP3/BARS) PX-04-070 SH3BGRL3, glutaredoxin-like protein Bolognesi Genova PX-04-071 The structure of a cell wall invertase from Rabijns Leuven Arabidopsis thaliana PX-04-072 Structure of Triticum aestivum xylanase inhibitor Rabijns Leuven II (TAXI II) PX-04-073 Structure of TAXI-I endoxylanase complex Rabijns Leuven soaked with different arabinoxylans PX-04-074 Rab-Geranylgeranyl transferase:Rab Escort Blankenfeldt Dortmund Protein:Rab7 complex PX-04-075 A new class of pectate lyases in complex with its Rabijns Leuven ligand PX-04-076 Rab-Geranylgeranyl transferase:Rab Escort Blankenfeldt Dortmund Protein inhibitor complex PX-04-077 Rab-Geranylgeranyl transferase:Rab Escort Blankenfeldt Dortmund Protein inhibitor complex PX-04-078 Structure of inactivated fructan-exohydrolase IIa Rabijns Leuven in complex with ligands PX-04-079 Structure of an endoxylanase which is no longer Rabijns Leuven inhibited by proteinaceous endoxylanase inhibitors PX-04-080 Rap1:Rap1GAP complex Blankenfeldt Dortmund PX-04-081 StyR: styrene-catabolism regulator in Bolognesi Genova Pseudomonas fluorescens PX-04-082 Structure of "truncated" hemoglobin HbO from Bolognesi Genova M. leprae PX-04-083 Studies of mutants of "truncated" hemoglobins Bolognesi Genova PX-04-084 Rho associated kinase Blankenfeldt Dortmund PX-04-085 Study of cytoglobin cavities with proper ligand Bolognesi Genova PX-04-086 Structure of drosophila melanogaster hemoglobin Bolognesi Genova PX-04-087 Methyltransferase aviRb Schulz Freiburg PX-04-088 Protein phosphatase 5 Barford London PX-04-089 Glycosyltransferases from Streptomyces Schulz Freiburg PX-04-090 Phenylalanine ammonia-lyase (PAL) Schulz Freiburg PX-04-091 Atomic resolution crystallography of TIM- Wierenga Oulu transition state complexes PX-04-092 Protein engineering: towards a new substrate Wierenga Oulu specificity of a monomeric variant of TIM PX-04-093 Adaptor proteins (continuation of PX-03-317, Gajhede Copenhagen 390, 391, and 403) PX-04-094 Cell adhesion molecules (continuation of PX-03- Gajhede Copenhagen 335 and 336) PX-04-095 Ionotropic glutamate receptors (continuation of Gajhede Copenhagen PX-03-330 and 334) PX-04-096 Enzymes and enzyme-ligand complexes Gajhede Copenhagen (continuation of PX-03-328, 331, and 389) PX-04-097 ToxB Schulz Freiburg PX-04-098 Structural investigation of the Betaine carrier Kuehlbrandt Frankfurt am BetP from C. bacterium glutamicum