Index acanthosis nigricans 4 (table) benign migratory glossitis (erythema benign type 5 (table) migrans; geographic tongue) 2 acne rosacea 40--3 blastomycosis 7 (table) sclerokeratitis 41 blepharitis 35--40 treatment 42-3 anergic 43 acrodermatitis enteropathica (Danbolt- classification 35 (table) Closs syndrome) 5 (table) rosacea 40--3 acromegaly 55 treatment 42-3 actinic granuloma of O'Brien 75 seborrhoeic 36 Addison's disease 4 (table) staphylococcal 36 agammaglobulinaemia, sex-linked 24 treatment 39--40 (table) Bloch-Sulzberger syndrome allergic eye disease 43-9 (il1lcontinentia pigmenti) 5 (table), hypertrophic papillae 54 (table) (cobblestones) 45-6 Bloom syndrome 4 alopecia, granulomatous 72 bull om. dermatoses 49-53 5-amino-laevulinate synthase 87 bullou~. disease of childhood, amyloidosis 4 (table) chronic 50 anaemia 7 (table) bullous pemphigoid 15 angioedema of lips 25 (table) angioid streaks 55-6 calcinosis cutis 75 angular cheilitis (angular cheilosis; candidosis, chronic mucocutaneous angular stomatitis; perleche) 26- candidosis endocrinopathy 8 syndrome 24 (table) ataxia telangiectasia 24 (table) cataract 54 atopic dermatitis 54 (table) steroid 56 atypical facial necrobiosis of Dowling chalazion (meibomian cyst) 37,38 and Wilson-Jones 75, 76-7 (fig.), 40 chalazoderma 72 Chediak-Higashi syndrome 25 (table) Beh~et's syndrome 4 (table), 7 cheilitis glandularis 25 (table) (table), 21-3 cheilitis granulomatosa 25 (table), 29 109 INDEX chickenpox 4 (table) Ehlers-Danlos syndrome chloroquine 58-9 (fibrodysplasia hyperelastica) 5 chondroectocermal dysplasia (Ellis-van (table), 55 Creveld syndrome) 5 (table) Ellis-van Creveld syndrome coeliac disease 7 (table) (chondroectodermal dysplasia) 5 congenital dyskeratosis (Schiifer's (table) syndrome) 54 (table) epidermolysis bullosa 5 (table), 7 congenital ichthyosiform (table) erythroderma 54 (table) erythema migrans (benign migrator)' congenital skin atrophy (Siemen's glossitis; geographic tongue) 2 syndrome) 54 (table) erythema multiforme 7 (table), 13-15, conjunctivitis 23 (table), 72 allergic, acute/chronic 44 erythema multi forme-like lesions 72 vernal 44-5 erythema nodosum 62-3, 64 (fig.) bulbar 46 erythroplasia 9 limbal 46-7 eyelids, contact sensitivity 53--4 palpebral 46-7 treatment 47-8 contact sensitivity 53--4 Fabry syndrome 5 (table) Cowden syndrome (multiple hamartoma Felty's syndrome 7 (table) and neoplasia syndrome) 5 (table) fibrodysplasia hyperelastica (Ehlers- Coxsackie viruses 7 (table) Danlos syndrome) 5 (table), 55 Crohn's disease focal dermal hypoplasia (Goltz cutaneous 77 syndrome) 5 (table) lips 25 (table) Fordyce spots (ectopic sebaceous oral 7 (table), 29-31 glands) 2 cytotoxic agents 7 (table) Danbolt--Closs syndrome Gardner's syndrome 5 (table) (acrodermatitis enteropathica) 5 geographic tongue (erythema migrans; (table) benign migratory glossitis) 2 Darier-Roussy sarcoids (subcutaneous gingivitis sarcoidosis) 68,69 (fig.) acute ulcerative 7 (table) Darier-White disease 5 (table) desquamative 9 (fig.) deficiency states 7 ( table) Goltz syndrome (focal dermal dermatitis herpetiformis 7 (table), 16, hypoplasia) 5 (table) 23 (table) Gorlin-Goltt syndrome (multiple basal desquamative gingivitis 9 (fig.) cell naevi syndrome) 5 Di George syndrome 24 (table) graft-versus-host disease 24 (table) Dowling-Wilson Jones syndrome 75, granuloma annulare 75, 77 (fig.) 76-7 granulomatosis 25 (table), 29 dyskeratosis congenita (Zinsser­ granulomatous disease, chronic 25 Engmann--Cole syndrome) 5 (table) (table) Gronblad-Strandberg syndrome (pseudoxanthoma e1asticum) 6 ectodermal dysplasia 5 (table), 54 (table), 55 (table) Gunther's disease (congenital ectopic sebaceous glands (Fordyce erythropoietic porphyria) 86 spots) 2 (table), 88 (table), 89 (table), 96-7 110 INDEX harderoporphyria 90 (table) lead poisoning 55 haem leukoedema 2 biosynthesis 84 (fig.), 87 leukopenia 7 (table) precursor overproduction 84 (fig.), leukaemia 7 (table) 87 Jichen planus 6-11,23 (table) hairy tongue 2 aetiology 9-10 hand, foot and mouth disease 4 (table) clinical appearance 8-9 hereditary angioedema 24 (table) diagnosis 10-11 hereditary benign intraepithelial management 11 dyskeratosis 5 (table) prognosis 9 hereditary coproporphyria 86 (table), linear 19A disease 88 (table), 100 ocular lesions 50, 52 homozygous 90 oral lesions 7 (table), 16,23 (table) inheritance 89 (table) lip hereditary haemorrhagic diseases involving 23-31 telangiectasia 5 (table) swellings 25 (table) herpes labialis, recurrent 28-9 tumours 25 (table) herpesviruses 7 (table) lipoid proteinosis (hyalinosis cutis et histoplasmosis 7 (table) mucosae; Urbach-Wiethe human immune deficiency virus 7 syndrome) 5 (table) (table), 24 (table) Lofgren's syndrome 63 hyalinosis cutis et mucosae (lipoid lupus erythematosis 4 (table), 7 (table). proteinosis; Urbach-Wiethe 19-21,23 (table) syndrome) 5 (table) lupus pernio 62, 69-70 hydroxychloroquine 58 lupus vulgaris 65, 66 (fig.) hyper-IgE syndrome (Job's syndrome) 25 hypertrichosis McCune-Albright syndrome 4 (table) gingival hyperplasia associated Maffucci syndrome 6 (table) porphyrial 92 measles 4 (table) meibomian cyst (chalazion) 37,38 immunodeficiency, common (fig.),40 variable 24 (table) meibomian gland disease 36-9 incontinentia pigmenti (Bloch­ meibomian keratoconjunctivitis 37-8, Sulzberger syndrome) 5 (table), 40 54 (table) meibomian seborrhoea 39 infantile poikiloderma (Rothmund's meibomitis 37-9 syndrome) 54 treatment 39-40 Jadassohn-Lewandowski syndrome Melkersson-Rosenthal syndrome 25 (pachyonychia congenital 5 (table), 29, 77 (table) mepacrine 59 Job's syndrome (hyper-IgE 8-metboxypsoralen 57 syndrome 25 (table) Mibelli's disease (porokeratosis) 6 (table) Kawasaki's disease (mucocutaneous Miescher's granulomatous cheilitis 77, lymph node syndroine) 4 (table) 78 kerato-conjunctivitis, adult atopic 48- mouth 9 disease relationships 3--6 K viem-Siltzbach test 70-1 normal/benign variants 2 111 INDEX mucocutaneous lymph node syndrome porphobilinogen synthase (Kawasaki's disease) 4 (table) deficiency 85, 86 (table), 88 (table) mucous membrane pemphigoid 11-13 porphyria 83-107 multiple basal cell naevi syndrome acute hepatic 86 (table), 88, 99-100 (Gorlin-Goltz syndrome) 5 management 107 (table) acute intermittent 85, 86 (table), 88 multiple hamartoma and neoplasia (table) syndrome (Cowden syndrome) 5 inheritance 89 (table) (table) autosomal dominant homozygous mycobacterial infection 7 (table) forms 90 (table) myeloperoxidase deficiency 25 (table) biochemical genetics 89-90 classification 85 necrobiosis lipoidica 75 congenital (Gunther's disease) 4 neurofibromatosis 6 (table) (table), 86 (table), 89 (table), 96-7 neutropenia diagnosis 101-4 chronic benign 25 (table) latent porphyria 104-5 cyclic 24 (table) hepatoerythropoietic 90 (table) hereditary coproporphyria 86 (table) histopathology 94 oral mucosa I hypertrichosis 92 oral ulceration 7 (table) inherited 89 (table) management 105-7 pachyonychia congenita (Jadassohn­ metabolic abnormalities 86-8 Lewandowski syndrome) 5 porphobilinogen (PBG)-synthase (table) deficiency 85 Paget's disease 55 prevalence 85-6 papillomavirus infections 4 (table) prevention of light-induced skin Papillon-Lefevre syndrome 6 (table) damage 105 pemphigoid types 86 (table) bullous 23 (table) variegate 86 (table), 88 (table), 100 mucous membrane 23 (table), 50,52 homozygous 90 ocular lesions 50-3 inheritance 89 (table) oral ulceration 7 (table) porphyria cutanea tarda 86,87,88 pemphigus foliaceus 50 (table), 93 (fig.), 97-9 pemphigus vulgaris inheritance 89 (table) conjunctivitis 49-50 treatment 106-7 oral lesions 7 (table), 17-19,23 porphyria cutanea tarda-type skin (table) lesions perleche (angular cheilitis) 26-8 adults 102-4 Peutz-Jeghers syndrome 6 (table) children 104 phenytoin 7 (table) porphyrins photo-onycholysis 91 mechanism of skin damage 95-6 pityriasis rosea 4 (table) photosensitization 87 pityriasis rubra pilaris 6 (table) clinical features 90-4 poliosis 56 protoporphyria (erythropoietic polyarteritis nodosa 4 (table), 23 protoporphyria; erythrohepatic (table) protoporphyria) 86 (table), 89, 91 porokeratosis (Mibelli's disease) 6 100-1 (table) homozygous 90 112 INDEX inheritance 89 (table) reactive lesions 62-3 liver disease 106 scar 68 prurigo 72 subcutaneous (Darier-Roussy nodular 72 sarcoids) 68,69 (fig.) pseudoxanthoma elasticum (Gronblad­ thrombophlebitis 72, 73 (fig.) Strandberg syndrome) 6 (table), vasculitis 72 55 vulval 75 psoralen/UVA (PUV A) therapy 57-8 Schafer's syndrome (congenital psoriasiform lesions 78 dyskeratosis) 54 (table) psoriasis 23 (table) scleroderma 4 (table) scleropoikiloderma (Werner's Reiter's syndrome 4 (table), 7 (table) syndrome) 54 (table) retinal disorders 54-6 selective IgA deficiency 24 (table) angioid streaks 55--6 severe combined immunodeficiency 24 rheumatoid nodules 77 (table) Rothmund's syndrome (infantile sicca syndrome 72 poikiloderma) 54 (table) sickle cell anaemia 55 Siemen's syndrome (congenital skin atrophy) 54 (table) sarcoidosis 61-2 Sjogren-Larsson syndrome 6 (table) actinic 75 staphylococcal hypersensitivity aestival 75 syndrome 40 alopecia 72 steroids 56 angiolupoid nodules 68 Sturge---Weber syndrome 6 (table) associated diseases 78--9 syphilis 7 (table) autoimmune disease? 78-9 conjunctival 72 dactylitis 74 teeth 1 elephantine 73 thiomersal 53 eruptive 74-5 tongue erythema multiforme see erythema fissured (scrotal) 2 multi forme geographic (erythema migrans; benign migratory glossitis) 2 formes sphace/iques 73 fulminant 72 hairy 2 granulomatous lesions 63-71 tuberose sclerosis 6 (table) hypopigmented 72-3, 74 (fig.) Trantas' spots 46 ichthyosis 72 tylosis 6 (table) K viem-Siltzbach test 70--1 lips 25 (table) ulcerative colitis 7 (table) micropapular 67,68 (fig.) Urbach-Wiethe syndrome (lipoid mucosal 72 proteinosis; hyalinosis cutis et nail 74 mucosae) 5 (table) 'naked granulomas' 65 uroporphyrin 96 nodules 67 oral lesions 4 (table) palmoplantar 74 Werner's syndrome papules 67 (scleropoikiloderma) 54 (table) perianal 75 white sponge naevus 6 (table) plaques 69--70 Wickham's striae 8 113 INDEX Wiskott-Aldrich syndrome 24 (table) Zinsser-Engmann-Cole syndrome (dyskeratosis congenita) 5 (table) xanthomatosis 6 (table) zoster 4 (table) xeroderma pigmentosum 6 (table) 114 .