PRODUCT DATA SHEET Bioworld Technology,Inc. ZNF408 polyclonal antibody Catalog: BS71268 Host: Rabbit Reactivity: Human,Mouse,Rat BackGround: by affinity-chromatography using epitope-specific im- Zinc-finger proteins contain DNA-binding domains and munogen and the purity is > 95% (by SDS-PAGE). have a wide variety of functions, most of which encom- Applications: pass some form of transcriptional activation or repression. WB 1:500 - 1:2000 The majority of zinc-finger proteins contain a Krüp- IHC 1:50 - 1:200 pel-type DNA binding domain and a KRAB domain, Storage&Stability: which is thought to interact with KAP1, thereby recruit- Store at 4°C short term. Aliquot and store at -20°C long ing histone modifying proteins. As a member of the term. Avoid freeze-thaw cycles. Krüppel C2H2-type zinc-finger protein family, ZNF396 Specificity: (zinc finger protein 396), also known as PRDM17 (PR ZNF408 polyclonal antibody detects endogenous levels domain zinc finger protein 17), is a 720 amino acid nu- of ZNF408 protein. clear protein that contains 10 C2H2-type zinc fingers. The DATA: gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syn- drome, Jacobsen syndrome, Niemann-Pick disease, he- reditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chro- mosome 11. Product: Western blot analysis of extracts of various cells, using ZNF408 anti- Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, body. 50% glycerol, pH7.2 Note: Molecular Weight: For research use only, not for use in diagnostic procedure. ~ 78 kDa Swiss-Prot: Q9H9D4 Purification&Purity: The antibody was affinity-purified from rabbit antiserum Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add： 1660 South Highway 100, Suite 500 St. Louis Park, Add： No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151 .