Supplementary Table 7 A. niger CBS 513.88 gene expression Gene name day3 day3 day3_Detection day5 day5_ day5_Detection Descriptions Signal Detection p-value Signal Detection p-value An01e00180 3.9 A 0.216384 15.7 P 0.04219 trnaKctt An01e00230 42.2 P 0.02493 51.1 P 0.001437 trnaDgtc An01e01100 10 A 0.07897 24.1 P 0.001851 5S ribosomal RNA An01e01100 58.8 P 0.001109 61.1 P 0.001437 trnaPagg An01e01570 14.2 A 0.406973 6.8 A 0.437665 trnaItat An01e01910 4.4 A 0.759912 3.8 A 0.5 trnaAtgc An01e02450 56.6 P 0.017085 65.3 P 0.017085 trnaDgtc An01e02580 38 A 0.085938 61.5 P 0.009766 trnaMcat An01e02710 44.7 P 0.011455 35.7 P 0.02987 transposon Vader - Aspergillus niger An01e03830 14.9 A 0.173261 16.7 A 0.240088 trnaEttc An01e03890 8.8 A 0.376842 17 A 0.265142 trnaEttc An01e04290 4.8 A 0.173261 1.3 A 0.406973 trnaMcat An01e04780 127.9 P 0.001437 84.9 P 0.001109 trnaVcac An01e05430 184.6 P 0.00302 98.6 P 0.001851 trnaVaac An01e05550 3.9 A 0.70854 0.5 A 0.805907 trnaTagt An01e06590 3 A 0.652557 0.6 A 0.95781 trnaFgaa An01e06680 131.4 P 0.001109 86.6 P 0.001109 trnaVcac An01e07610 90.6 P 0.04974 68.1 P 0.02987 trnaLaag An01e07880 62 P 0.000977 55.4 P 0.000977 trnaEctc An01e08320 25.9 A 0.173261 22 A 0.265142 trnaSgct An01e08330 22.9 A 0.194093 15.8 A 0.318935 trnaSgct An01e08340 17.8 A 0.194093 7.4 A 0.623158 trnaSgct An01e08350 19.1 A 0.318935 7.8 A 0.437665 trnaSgct An01e08940 36.6 P 0.014028 30.9 P 0.017085 trnaHgtg An01e09990 9.1 A 0.437665 11.7 A 0.562335 trnaSaga An01e10260 18.4 P 0.04219 18.4 A 0.173261 trnaAtgc An01e11040 115.3 P 0.001109 81.9 P 0.001109 trnaQctg An01e11050 30 A 0.27417 21.8 A 0.19458 trnaQttg An01e11060 39.6 P 0.002371 27.4 P 0.004816 trnaQctg An01e11230 104 P 0.003825 121 P 0.001109 transposon Vader - Aspergillus niger An01e11460 6.9 A 0.531264 3.4 A 0.468736 trnaCgca An01e11490 31.9 M 0.058332 39.1 P 0.02987 trnaSaga An01e11980 99.3 P 0.011455 50.7 P 0.035595 trnaYgta An01e12140 141.4 P 0.001109 117.5 P 0.001109 trnaGgcc An01e12510 36.3 A 0.136048 20.2 A 0.07897 trnaScga An01e12650 41.5 P 0.009301 47.7 P 0.007511 trnaVcac An01e12870 88.2 P 0.004816 70.7 P 0.014028 trnaLaag An01e12900 78 P 0.017085 67.9 P 0.02493 trnaLaag An01e12930 14.4 A 0.29146 13.1 A 0.376842 trnaSaga An01e13800 66.3 P 0.000977 63.3 P 0.000977 trnaEctc An01e15090 5 A 0.468736 2.2 A 0.562335 probable transposon Tndm3 - Aspergillus niger An01g00010 2 A 0.863952 8.1 A 0.652557 hypothetical protein [truncated ORF] An01g00020 23.3 A 0.318935 29.8 A 0.406973 weak similarity to nucleotide binding protein phnN - Escherichia coli An01g00030 394.2 P 0.002371 381.5 P 0.002371 strong similarity to HGH1 - Saccharomyces cerevisiae An01g00040 192.6 P 0.014028 285.4 P 0.006032 strong similarity to alpha subunit of transcription initiation factor TFIIF TFG1 - Saccharomyces cerevisiae [truncated ORF] An01g00050 57.3 M 0.058332 168.7 P 0.004816 similarity to fatty-acyl-CoA synthase beta chain FAS1 - Saccharomyces cerevisiae [truncated orf] An01g00060 776.2 P 0.001109 791.8 P 0.001109 strong similarity to fatty acid synthase, subunit alpha FAS2 - Schizosaccharomyces pombe An01g00070 73.9 P 0.020695 73.5 P 0.006032 strong similarity to N2,N2-dimethylguanosine tRNA methyltransferase trm1 - Schizosaccharomyces pombe An01g00080 98.7 P 0.001437 84.8 P 0.001437 weak similarity to probable membrane protein YOR228c - Saccharomyces cerevisiae An01g00090 35.3 A 0.437665 45.3 A 0.376842 weak similarity to hypothetical protein F21E10.7 - Arabidopsis thaliana An01g00100 950.1 P 0.001109 1046.6 P 0.001109 strong similarity to pyruvate dehydrogenase beta chain precursor PDB1 - Saccharomyces cerevisiae An01g00110 251.5 P 0.011455 272.5 P 0.007511 strong similarity to hypothetical protein SPAC1039.02 - Schizosaccharomyces pombe An01g00120 268.7 P 0.001109 295.1 P 0.001109 similarity to mitochondrial respiratory function protein MRF1 - Saccharomyces cerevisiae An01g00130 83.8 P 0.002371 81.3 P 0.001437 strong similarity to glutamyl-tRNA (Gln) amidotransferase chain A gatA - Bacillus subtilis An01g00140 22.4 A 0.173261 16 A 0.104713 weak similarity to trithorax protein ash2 - Drosophila melanogaster An01g00150 258.9 P 0.001109 288.2 P 0.001437 strong similarity to nuclear protein ENP1 - Saccharomyces cerevisiae An01g00160 1373.5 P 0.001109 1319.3 P 0.001437 similarity to regulator of unfolded protein response (UPR) Hac1p - Saccharomyces cerevisiae An01g00170 223.1 P 0.011455 208.9 P 0.014028 similarity to FTI1 protein - Saccharomyces cerevisiae An01g00190 3.5 A 0.931951 7.8 A 0.941668 similarity to PRIB protein - Lentinus edodes An01g00200 129 P 0.002371 108.7 P 0.002371 strong similarity to succinyl-CoA:3-ketoacid-CoA transferase SCOT - Homo sapiens An01g00210 40.7 A 0.136048 46.6 A 0.136048 hypothetical protein An01g00220 36.8 A 0.29146 62 A 0.136048 strong similarity to hypothetical membrane protein YJR124c - Saccharomyces cerevisiae [truncated] An01g00240 13.6 A 0.759912 22.6 A 0.531264 strong similarity to cytochrome P450 protein 4F5 - rattus norvegicus An01g00250 2.5 A 0.964405 3.2 A 0.95781 strong similarity to nitrate reductase NR2 - Arabidopsis thaliana An01g00260 1.4 A 0.783616 1.5 A 0.805907 strong similarity to hypothetical transcription activator SPAC139.03 - Schizosaccharomyces pombe An01g00270 32.4 A 0.240088 30.2 A 0.194093 similarity to fluconazole resistance protein FLU1 - Candida albicans [putative frameshift] An01g00280 123.6 P 0.003825 226.4 P 0.001437 strong similarity to hypothetical protein PAC823.14 - Schizosaccharomyces pombe An01g00290 102.4 P 0.017085 38.7 A 0.153911 similarity to the hypothetical protein encoded by An17g00430 - Aspergillus niger An01g00310 1.1 A 0.783616 2.5 A 0.805907 strong similarity to the hypothetical protein encoded by An02g10090 - Aspergillus niger An01g00320 11.5 A 0.406973 10.1 A 0.468736 similarity to the hypothetical protein encoded by An08g08380 - Aspergillus niger An01g00330 8 A 0.376842 24.3 A 0.136048 alpha-l-arabinofuranosidase a precursor abfA - Aspergillus niger An01g00340 384.5 P 0.001437 354.3 P 0.001109 strong similarity to hypothetical protein SPCC320.08 - Schizosaccharomyces pombe An01g00360 4.3 A 0.92103 3 A 0.95781 hypothetical protein An01g00370 60.9 A 0.216384 193.2 P 0.011455 strong similarity to aspergillopepsin apnS - Aspergillus phoenicis An01g00380 15.6 A 0.29146 11 A 0.29146 similarity to monocarboxylate transporter MCT3 - Homo sapiens An01g00390 116 P 0.04219 107.6 A 0.068049 hypothetical protein An01g00400 69.6 P 0.04974 67.5 P 0.04219 strong similarity to hypothetical protein SPBC12C2.09c - Schizosaccharomyces pombe An01g00420 36.9 A 0.29146 33.8 A 0.136048 strong similarity to the hypothetical protein encoded by An01g01580 - Aspergillus niger An01g00430 133 P 0.011455 50.6 P 0.04219 similarity to heterokaryon incompatibility protein het-6 - Neurospora crassa An01g00450 5.1 A 0.652557 3.7 A 0.562335 similarity to 3-hydroxyisobutyrate dehydrogenase mmsB - Pseudomonas aeruginosa An01g00460 102.8 P 0.001109 179.3 P 0.001109 hypothetical protein An01g00470 4.9 A 0.468736 19.4 A 0.194093 strong similarity to hypothetical protein jhp0584 - Helicobacter pylori An01g00480 72.5 P 0.001437 24.7 P 0.006032 strong similarity to the hypothetical protein encoded by An08g06260 - Aspergillus niger An01g00490 4.8 A 0.681065 24.7 A 0.562335 strong similarity to isoamyl alcohol oxidase mreA - Aspergillus oryzae An01g00500 21.5 A 0.07897 11 A 0.347443 hypothetical protein An01g00510 29.4 P 0.035595 19.2 A 0.068049 strong similarity to cytochrome P450 cyp52A3-a - Candida maltosa An01g00520 30.2 A 0.091169 28.3 A 0.119658 hypothetical protein An01g00520 19 A 0.376842 15 A 0.437665 hypothetical protein An01g00530 86.7 P 0.017085 325.5 P 0.001437 proteinase aspergillopepsin II - Aspergillus niger An01g00540 6.1 A 0.734858 3 A 0.908831 hypothetical protein An01g00550 1.5 A 0.95026 1.1 A 0.95026 strong similarity to allergen rAsp f 4 - Aspergillus fumigatus An01g00560 407.5 P 0.001851 363.3 P 0.002371 strong similarity to microsomal signal peptidase SPC21 - Canis familaris An01g00570 3.2 A 0.895287 2.1 A 0.95026 hypothetical protein An01g00600 16 A 0.531264 3.6 A 0.681065 similarity to hypothetical protein YLR011w - Saccharomyces cerevisiae An01g00610 36.3 A 0.265142 40.7 A 0.119658 weak similarity to hypothetical protein yukJ - Bacillus subtilis An01g00620 51.3 A 0.153911 40.1 A 0.173261 strong similarity to p-cumic aldehyde dehydrogenase cymc - Pseudomonas putida An01g00630 31.9 P 0.04219 28.2 A 0.07897 strong similarity to benzyl alcohol dehydrogenase areB - Acinetobacter species An01g00640 33.7 P 0.011455 21.3 P 0.02493 weak similarity to ankyrin B - Homo sapiens An01g00650 10.5 A 0.29146 2 A 0.216384 hypothetical protein An01g00660 8.1 A 0.783616 7 A 0.70854 similarity to the hypothetical protein encoded by An04g06870 - Aspergillus niger An01g00670 4.1 A 0.70854 9 A 0.562335 hypothetical protein An01g00680 87.8 P 0.020695 87.3 P 0.017085 strong similarity to cytochrome P450 monooxygenase avnA - Aspergillus parasiticus An01g00690 8.6 A 0.681065 7.1 A 0.593027 weak similarity to YDR213w - Saccharomyces cerevisiae An01g00700 29.3 A 0.068049 19.9 A 0.153911 strong similarity to protein RTM1 - Saccharomyces cerevisiae An01g00710 25.5 A 0.406973 34.1 A 0.376842 strong similarity to aromatic amino acid decarboxylase ddc - Sorangium cellulosum An01g00720 34.5 A 0.173261 27.4 A 0.29146 strong similarity to multi drug transporter bmr3 - Bacillus subtilis An01g00730 21.4 A 0.265142 15.7 A 0.265142 hypothetical protein [truncated ORF] An01g00740 48.6 A 0.07897 68.5 P 0.04219 hypothetical protein [truncated orf] An01g00750 944.8