Winter/Spring 2020 Forewords from the Head Dear DoCS: Faculty & Staff Updates This has been a remarkable Awards/Congratulations year, but with the changes Grants in how meetings are run, Books, Papers and has given me the Accomplishments opportunity to see how In the News Departmental meetings Postdoc, Graduate Student work at the cabinet, group & Resident News and individual level. Who Am I Hopefully, that will make the Other News and Updates transition easier. At this point, it seems as if we are going to have to get used to the new zoom-dominated environment for a long time to come. I want to thank the faculty, staff, house officers, and graduate students for all of their efforts to keep teaching and clinical commitments going. I realize this has been an immense effort, and I am grateful for everyone’s team spirit. Hopefully, we can all learn new teaching techniques that will become a part of how we approach students in the future. I have realized more than ever what a remarkable department DoCS is, and I am proud to have been selected to lead us forward. I want to particularly thank Lizette for all of her guidance over the transition. Fortunately for all of us, she will remain at NC State, and will continue on as co-Assistant Department Head (with Greg Lewbart) within the MSM group. I am in the process of moving into the Department office, so if you are in the CVM, please feel free to drop by for an impromptu socially-distanced meeting! Best wishes to everyone as new challenges approach in the upcoming Fall semester --Anthony _ _ _ _ _ _ _ _ _ _ Faculty & Staff Updates New Employees Dr. Mariea Ross-Estrada started on December 19, 2019 as an Assistant Clinical Professor of Small Animal General Practice. 1 Dr. Diane Deresienski started on December 30, 2019 as an Associate Clinical Professor of Small Animal General Practice. Dr. Alix Berglund moved into a Research Scholar position on January 1, 2020. Dr. Nicholas de Castro started on January 10, 2020 as a Research Associate in Dr. Duncan Lascelles Lab. Dr. Yu Ueda started on February 3, 2020 as an Assistant Clinical Professor of Emergency and Critical Care. Dr. LaTisha Knight started on March 2, 2020 as an Assistant Clinical Professor of Ophthalmology. Dr. Katarzyna Dembek started on March 31 2020 as an Assistant Professor of Equine Internal Medicine. Dr. Allison Kendall started on June 1, 2020 as an Assistant Clinical Professor of Small Animal Internal Medicine. Departing Faculty and Staff Beth Lubeck – December 7, 2019 Dr. Freya Mowat – December 31, 2019 Dr. Caitlin O’Shea – January 16, 2020 Faculty Recruitment Updates Dr. Jose Len has been hired as an Assistant Professor of Theriogenology. He will start in 2020. Dr. Sarah Ozawa will start on August 31, 2020 as an Assistant Clinical Professor of Avian-Exotic Medicine. Dr. Annie Oh will start on August 31, 2020 as an Assistant Clinical Professor of Ophthalmology. We are in the process of recruiting for a faculty position in Dentistry and Oral Surgery, and hope to re-open searches for faculty positions in Dermatology, Cardiology, and Equine Orthopedics. The latter searches were closed earlier this year due to Covid-19 restrictions. _ _ _ _ _ _ _ _ _ Awards/Congratulations was promoted to Research (December 2019 – May 2020) Dr. Ricardo Maggi Professor effective July 1, 2020. Dr. Anthony Blikslager received the AVMA Dr. Steve Marks received the Huffman Clinical Research Award, American Veterinary th Medical Association in Schaumburg, IL. May Leadership Award at the 36 Annual CVM 2020. Awards Ceremony. Dr. Laura Nelson received the Class of 2021 Dr. Dianne Dunning was promoted to Clinical th Professor effective July 1, 2020. CVM Faculty Award at the 36 Annual CVM Awards Ceremony. Dr. Lizette Hardie received the AAVC Faculty Award. Dr. Thierry Olivry was awarded the European College of Veterinary Dermatology (ECVD) Dr. Karyn Harrell received the Class of 2020 Lifetime Career Award. This award is given CVM Faculty Award at the 36th Annual CVM every four years to a senior ECVD diplomate Awards Ceremony. who has made major scholarly, scientific, educational or political contributions to Dr. Kate Meurs has been named Senior veterinary dermatology in Europe and the Associate Dean and Director for Research and World. Graduate Studies. The new addition to her title - “Senior” - is in recognition of her nearly 10 Dr. Barbara Qurollo was promoted to years of service to the college, and the Associate Research Professor effective July 1, extensive additional responsibilities she has 2020. taken on in the past few years. 2 Dr. Lauren Schnabel was awarded the NCSU pain in Sled Dogs, and determine its use as a 2020 Zoetis Award for Veterinary Research prognostic marker. $4,000. Excellence at the 36th Annual CVM Awards Ceremony. Gruen ME (PI), Lascelles BDX (Co-I). Do dog breeds differ in pain sensitivity? Separating fact Dr. Amy Snyder was promoted to Associate from perception. We will test the assumption Clinical Professor effective July 1, 2020. that dog breeds differ in sensitivity. We will achieve this primarily through QST applied to Dr. Sarah Townsend became a diplomate of various breeds, and concurrently gather ‘omic the American College of Veterinary Surgeons- and microbiome data to help understand Small Animal. differences we find. We will also test this _ _ _ _ _ _ _ _ _ _ assumption through an analysis of clinical data on pain scores and analgesic use across Grants Received different breeds. $104,147. (December 2019 – May 2020) Lascelles BDX (PI). A pilot multi-center, Chiu KW, Duffy DJ (PI), Chang YC, Fisher masked, randomized clinical field study to MB. Description of novel locking tenorrhaphy evaluate the effectiveness and safety of patterns for canine flexor tendon repair. resiniferatoxin (rtx) compared to a sham Investigator Grant for research for $12,000 injection for the control of pain associated with awarded at Veterinary Orthopedic Society osteoarthritis. This is pilot work to assess our conference in Sun Valley, Idaho, February capability in performing a larger clinical trial. 2020. Duffy: Mentor, Lead Investigator, $16,751. Corresponding author. Lascelles BDX (PI). Prevalence of Harms C. Temporary threshold shifts in hearing osteoarthritis in young dogs and response to in aquatic turtles. Prime: US Navy-ONR; Direct: treatment. We will determine the prevalence of Woods Hole Oceanographic Institution. 2020- the disease of osteoarthritis in dogs less than 4 21. $12,677. years old, and also determine the prevalence of pain associated with this. $508,230. Harrison TM (Co-I). NIH supplement. Characterization of elephant tumor evolution. Mishra SK, Olivry T - Co-PI. Investigations on 2019; $20,014. the role of the indoor environmental stressor house dust mite in atopic dermatitis. NCSU Harrison TM (Co-PI). TriCEM, A cross species Center for Human Health and the Environment, analysis of the mutational landscape of cancer. Raleigh, North Carolina. 2020-2021; $25,000. 2020; $7,000. Schnabel LV - PI, Messenger K – Co-I. Lascelles BDX (PI). A wearable sensor study Grayson-Jockey Club Research Foundation, to measure response of a therapeutic food in Inc. “Enhancing the efficacy of MSCs for tendon overweight adult dogs with osteoarthritis. healing.” 2020-2022; $100,686. We will assess the benefit of a therapeutic food in terms of minimizing the signs of osteoarthritis Schnabel LV - PI, Gilbertie J – CO-I. NIH pain in dogs, and concurrently develop (NIAID) STTR with Direct Sponsor Synoxa algorithms for the detection of osteoarthritis Sciences, Inc (Pierce). “Development of natural pain using high-frequency longitudinal product inspired adjuvants to treat tolerant accelerometry data acquisition. $315,094. infections.” 2020-2022; $235,266. _ _ _ _ _ _ _ _ _ _ Lascelles BDX (PI). Investigating artemin: a potential diagnostic marker for osteoarthritis Abstracts, Books, Papers associated joint pain in sled dogs. We will evaluate the role of artemin in osteoarthritis Published and Accomplishments 3 (December 2019 – May 2020) 10.1016/j.domaniend.2020.106470. Epub 2020 Mar 6. PMID: 32408050 Krüger L, Pridgen TA, Taylor ER, Garman ES, Blikslager AT. Lubiprostone protects Duffy DJ, (PI) Curcillo CP, Chang YJ, Gaffney esophageal mucosal from acid injury in porcine L, Fisher MB, Moore GE. Biomechanical esophagus. Am J Physiol Gastrointest Liver evaluation of an autologous flexor digitorum Physol 2020;3218:G613-G623. lateralis graft to augment the surgical repair of gastrocnemius tendon laceration in a canine ex Plundrich NJ, Smith AR, Borst LB, Snider DB, vivo model [published online ahead of print, Kaeser T, Dellon ES, Blikslager AT, Odle J, 2020 Jun 14]. Vet Surg. Lila MA, Laster SM. Oesophageal eosinophilia 2020;10.1111/vsu.13453. accompanies food allergy to hen egg white doi:10.1111/vsu.13453. protein in young pigs. Clin Exp Allergy. 2020;50:95-104. Duffy DJ, (PI) Moore GE. Influence of Blikslager AT, Mair TS. Trends in the oversewing the transverse staple line during management of horses referred for evaluation functional end-to-end stapled intestinal of colic: 2004-2017. Equine Vet Educ, Epub anastomoses in dogs [published online ahead ahead of print, 2020. of print, 2020 Jun 5]. Vet Surg. 2020;10.1111/vsu.13451. Jin Y, Blikslager AT. The regulation of doi:10.1111/vsu.13451. intestinal mucosal barrier by myosin light chain kinase/rho kinases. Int J Mol Sci. Duffy DJ, (PI) Chang YJ, Balko JA, Moore GE. 2020;21:E3550. Effect of presurgical storage conditions on leakage pressures of enterotomy sites closed Slifer ZM, Blikslager AT. The integral role of with unidirectional barbed suture material in tight junction proteins in the repair of injured fresh, chilled, and frozen-thawed cadaveric intestinal epithelium. Int J Mol Sci canine jejunal specimens.