July 23-27, 2018 Asia-Pacific NEURO-ONCOLOGY FAIRMONT ORCHID HOTEL CME CONFERENCE WAIMEA, HAWAII Join us for our inaugural 5-day comprehensive educational conference on neuro-oncology. Presenters from around the world will share their expertise on this ever evolving multi-disciplinary field. Register by June 4, 2018 to receive $100 off your registration fee! COURSE DIRECTOR Tracy Batchelor, M.D. Massachusetts General Hospital Cancer Center COURSE CO-DIRECTORS Nino Chiocca, M.D., Ph.D. Nancy Tarbell, M.D. Brigham and Women’s Hospital Harvard Medical School Jay Loeffler, M.D. Patrick Wen, M.D. Massachusetts General Hospital Dana-Farber Cancer Institute www.hms-apno.com General Information Overview Neuro-oncology is a rapidly evolving multi-disciplinary field, which involves the medical, surgical and radiation management of adult and pediatric patients with primary and metastatic brain and spinal cord tumors. In addition, modern molecular neuropathology and neuroradiology concepts are essential for accurate diagnosis and classification. This five-day CME course is designed to provide an international audience with a comprehensive review of the diagnosis and management of adult and pediatric patients with primary and metastatic brain and spinal cord tumors and neurologic complications of cancer. Target Audience This course is targeted to health care specialists involved in the care of adult and pediatric neuro-oncology patients (oncologists, radiation oncologists, neurosurgeons, neurologists, neuroradiologists, and Conference Site neuropathologists). FAIRMONT ORCHID HOTEL WAIMEA, HAWAII Learning Objectives Upon completion of this activity, participants will be able to: • Evaluate, diagnose and treat adult and pediatric patients with primary and metastatic central nervous system tumors Register Online • Appreciate the role of biomarkers in the diagnosis and treatment of brain and spinal cord tumors www.hms-apno.com • Recognize and address neurological complications associated with cancer and new cancer therapies • Discuss the role of palliative and supportive care in neuro-oncology Cancellation Policy Registration Fees Refunds, less an administrative fee of $75, will be issued for all cancellations Physician (MD/DO) $675.00 received at least two weeks prior to the Allied Health Professional/ Other $550.00 start of the course. No refund will be Industry $875.00 issued should cancellation occur less than two weeks prior. “No shows” are subject Early Registration Discount: Register by June 4, 2018 and to the full course fee. receive $100 off your registration fee. The participant registration fee includes all sessions, continental breakfasts, Welcome Reception on Monday, and Inquiries continuing education credit. Accompanying Guest - 12 and Over $100.00 BY PHONE: Accompanying guests may join conference participants during continental 1-617-384-8600 breakfasts and breaks (as part of the main conference) from Monday Monday - Friday, 9 am to 5 pm (ET) through Friday and the Welcome Reception on Monday. Registration by credit card (VISA, MasterCard or American Express) or check can BY EMAIL: be made through Harvard Medical School’s secure online registration system. [email protected] Registration by check (draft on a United States bank), please make payable to Harvard Medical School. Learners who choose to pay by check will be prompted to download an online form to send in with a payment. Telephone or fax registration is not accepted. Registration with cash payment is not permitted. Upon receipt of your paid registration, you will receive an email confirmation. Be sure to include an email address that you check frequently. Your email address is used for critical information including registration confirmation, evaluation and certificate. 2 www.hms-apno.com Accreditation The Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The Harvard Medical School designates this live activity for a maximum of 27.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. The Royal College of Physicians and Surgeons of Canada recognizes conferences and workshops held outside of Canada that are developed by a university, academy, hospital, specialty society or college as accredited group learning activities. Through an agreement between the American Medical Association and the European Union of Medical Specialists, physicians may convert AMA PRA Category 1 Credits™ to an equivalent number of European CME Credits® (ECMECs®). Information on the process of converting AMA PRA Category 1 Credits™ to ECMECs® can be found at: www.eaccme.eu. Disclosure Policy Harvard Medical School (HMS) adheres to all ACCME Accreditation Criteria and Policies. It is HMS’s policy that those who have influenced the content of a CME activity (e.g. planners, faculty, authors, reviewers and others) disclose all relevant financial relationships with commercial entities so that HMS may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations. Disclaimer CME activities accredited by Harvard Medical School are offered solely for educational purposes and do not constitute any form of certification of competency. Practitioners should always consult additional sources of information and exercise their best professional judgment before making clinical decisions of any kind. 3 Schedule July 22, 2018 Sunday 3:00-5:00 pm Registration Open July 23, 2018 Monday: Gliomas 7:00 am Registration/Breakfast 7:20 am Welcome 7:30 am Brain Tumor Biology 101: Genomics (Priscilla Brastianos, M.D.) 7:45 am Brain Tumor Epidemiology (Kyle Walsh, Ph.D.) 8:15 am Revised WHO Classification for Gliomas (Andreas von Diemling, M.D.) 8:45 am Advances in the Imaging of Gliomas (Leland Hu, M.D.) 9:15 am Surgical Advances in Glioma Management (Nino Chiocca, M.D., Ph.D.) 9:45 am Break 10:00 am Radiation Advances in the Treatment of Glioblastoma (Erik Sulman, M.D., Ph.D.) Chemotherapy for Newly Diagnosed Glioblastoma — Does MGMT Methylation 10:30 am Status Matter? (Wolfgang Wick, M.D.) 10:45 am Treatment of Recurrent Glioblastoma (Susan Chang, M.D.) 11:15 am Management of Glioblastoma in Elderly Patients (Sith Sathornsumetee, M.D.) Contemporary Issues in Neuro-Oncology: Role of Tumor Treatment Fields 11:45 am (Michael Weller, M.D.) 12:00 pm Adjourn 4 www.hms-apno.com July 24, 2018 Tuesday: Gliomas 7:00 am Breakfast 7:25 am Welcome 7:30 am Brain Tumor Biology 101: Metabolomics (Daniel Cahill, M.D., Ph.D.) 7:45 am Experimental Therapies for Glioblastoma — Surgical (Bob Carter, M.D., Ph.D.) 8:15 am Experimental Therapies for Glioblastoma — Medical (Frank Winkler, M.D.) 8:45 am Anaplastic Gliomas (Patrick Wen, M.D.) 9:15 am Low-Grade Gliomas (Andrew Chi, M.D., Ph.D.) 9:45 am Break 10:00 am Targeted Therapy for Gliomas (Isabel Arrillaga-Romany, M.D., Ph.D.) 10:30 am Immunotherapy for Gliomas (Michael Platten, M.D.) 11:00 am Spinal Cord Gliomas (Ganesh Shankar, M.D., Ph.D.) 11:30 am Ependymomas (Rakesh Jalali, M.D.) Contemporary Issues in Neuro-Oncology: PCV versus Temozolomide 11:45 am (Wolfgang Wick, M.D.) 12:00 pm Adjourn 1:30 – 4:30 pm Symposium 1: International Tumor Board — Glioma July 25, 2018 Wednesday: Non-Glial Tumors and Supportive Neuro-Oncology 7:00 am Breakfast 7:25 am Welcome 7:30 am Brain Tumor Biology 101: Tumor Tubules (Frank Winkler, M.D.) 7:45 am Pituitary Tumors (Jay Loeffler, M.D.) 8:15 am Meningiomas (Priscilla Brastianos, M.D.) 5 Schedule July 25, 2018 8:45 am Craniopharyngiomas (Bob Carter, M.D., Ph.D.) 9:00 am Primary CNS Lymphoma (Tracy Batchelor, M.D.) 9:30 am Break 9:45 am CNS Histiocytoses (Lakshmi Nayak, M.D.) 10:15 am Neurocognitive Issues in Brain Tumor Patients (Michael Parsons, Ph.D.) 10:45 am Supportive Care for Brain Tumor Patients (Sith Sathornsumetee, M.D.) 11:15 am Palliative Care for Brain Tumor Patients (Deborah Forst, M.D.) Contemporary Issues in Neuro-Oncology: Bevacizumab for Non-Glial Tumors 11:45 am (Scott Plotkin, M.D.) 12:00 pm Adjourn July 26, 2018 Thursday: Nervous System Metastases and Neurological Complications of Cancer 7:00 am Breakfast 7:25 am Welcome 7:30 am Brain Tumor Biology 101: Immunology (Michael Platten, M.D.) 7:45 am CNS Metastases — Biology (Priscilla Brastianos, M.D.) 8:15 am Brain Metastases — Surgery and Radiation (Ian Dunn, M.D.; Jay Loeffler, M.D.) 8:45 am Brain Metastases — Medical and Experimental Therapies (Riccardo Soffietti, M.D.) 9:15 am Leptomeningeal Metastases (Adrienne Boire, M.D., Ph.D.) 9:45 am Break 10:00 am Metastatic Epidural Spinal Cord Compression (Shota Tanaka, M.D.) 10:30 am Metastases to Plexus and Peripheral Nerve (Eric Wong, M.D.) 10:45 am Paraneoplastic Neurological Syndromes (Jorg Dietrich, M.D., Ph.D.) continued 6 www.hms-apno.com July 26, 2018 11:15 am Neurological Complications of New Cancer Therapies (Eudocia Q. Lee, M.D., M.P.H.) Contemporary Issues in Neuro-Oncology: WBRT for Brain Metastases 11:45 am (Jay Loeffler, M.D.) 12:00 pm Adjourn 1:30 - 4:30 pm Symposium 2: International Tumor Board — Non-Glial Tumors July 27, 2018 Friday: Pediatric Nervous System Tumors and Tumor Susceptibility Syndromes 7:00 am Breakfast