SEQ_ID GeneID fold change Gene name Description AhR-related genes Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle NM_024362 29657 6.102 Arntl ARNT-like 1)(Tic) [Source:UniProtKB/Swiss-Prot;Acc:Q9EPW1] PhaseⅠdrug metabolic enzymes NADP-dependent malic enzyme (NADP-ME)(EC 1.1.1.40)(Malic enzyme 1) NM_012600 24552 2.321 Me1 [Source:UniProtKB/Swiss-Prot;Acc:P13697] Cytochrome P450 4A10 (CYPIVA10)(Lauric acid omega-hydroxylase)(EC NM_153307 50549 2.680 Cyp4a1、Cyp4a10 1.14.15.3)(Cytochrome P450-LA-omega 1)(Cytochrome P452) [Source:UniProtKB/Swiss-Prot;Acc:P08516] XM_001080197 308190 2.338 Cyp26c1 Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 [ Rattus XM_001077204 502387 2.366 LOC502387 similar to cytochrome P450 2C66; CYP2C66 [ Rattus norvegicus ] Cytochrome P450 2B15 (EC 1.14.14.1)(CYPIIB15) [Source:UniProtKB/Swiss- XM_001077552 687215 2.048 Cyp2b31 Prot;Acc:Q64583] PhaseⅢdrug metabolic enzymes ATP-binding cassette, sub-family G (WHITE), member 4 [Source:RefSeq XM_001066633 300664 2.187 Abcg4 peptide;Acc:NP_001100286] NM_001015012 308821 2.271 Rab30 RAB30, member RAS oncogene family [Source:RefSeq DNA damage-and/or cell cycle related genes Proto-oncogene serine/threonine-protein kinase pim-1 (EC 2.7.11.1) NM_017034 24649 2.528 Pim1 [Source:UniProtKB/Swiss-Prot;Acc:P26794] Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage- NM_024127 25112 2.503 Gadd45a inducible transcript 1 protein)(DDIT-1) [Source:UniProtKB/Swiss- NM_080782 114851 7.312 Cdkn1a cyclin-dependent kinase inhibitor 1A [Source:RefSeq peptide;Acc:NP_542960] Growth arrest and DNA damage-inducible protein GADD45 gamma NM_001077640 291005 12.757 Gadd45g [Source:UniProtKB/Swiss-Prot;Acc:Q9WTQ7] XM_001064075 362485 2.299 Ccne2 cyclin E2 [Source:RefSeq peptide;Acc:NP_001102126] oxidatiev stress related genes XM_001054329 679752 2.224 LOC679752 similar to Glutaredoxin-1 (Thioltransferase-1) (TTase-1) [ Rattus norvegicus ] XM_001056352 680255 2.180 LOC680255 similar to Glutaredoxin-1 (Thioltransferase-1) (TTase-1) [ Rattus norvegicus ] XM_001081076 688082 4.086 LOC688082 similar to glutaredoxin 1 (thioltransferase) [ Rattus norvegicus ] Others Ephrin type-B receptor 1 Precursor (EC 2.7.10.1)(Tyrosine-protein kinase receptor XM_001059882 24338 2.523 Ephb1 EPH-2)(ELK) [Source:UniProtKB/Swiss-Prot;Acc:P09759] NM_012591 24508 2.416 Irf1 Interferon regulatory factor 1 (IRF-1) [Source:UniProtKB/Swiss-Prot;Acc:P23570] XM_001054999 24641 2.298 Flg filaggrin [ Rattus norvegicus ] NM_012630 24684 4.637 Prlr prolactin receptor [ Rattus norvegicus ] Glial cell line-derived neurotrophic factor Precursor (Astrocyte-derived trophic NM_019139 25453 2.155 Gdnf factor)(ATF) [Source:UniProtKB/Swiss-Prot;Acc:Q07731] Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)(Glutamine-dependent NM_013079 25612 2.082 Asns asparagine synthetase) [Source:UniProtKB/Swiss-Prot;Acc:P49088] NM_013092 25627 2.086 Cma1 chymase 1, mast cell [ Rattus norvegicus ] Glucose-6-phosphatase (G-6-Pase)(G6Pase)(EC 3.1.3.9) NM_013098 25634 2.176 G6pc [Source:UniProtKB/Swiss-Prot;Acc:P43428] Insulin-like growth factor-binding protein 1 Precursor (IGF-binding protein NM_013144 25685 10.786 Igfbp1 1)(IGFBP-1)(IBP-1) [Source:UniProtKB/Swiss-Prot;Acc:P21743] Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M)(EC 2.3.1.21)(Carnitine O-palmitoyltransferase I, muscle isoform)(CPTI-M)(CPT NM_013200 25756 2.029 Cpt1b I)(Carnitine palmitoyltransferase 1B)(Carnitine palmitoyltransferase I-like protein) [Source:UniProtKB/Swiss-Prot;Acc: NM_017115 29148 2.263 Myog Myogenin [Source:UniProtKB/Swiss-Prot;Acc:P20428] Choline kinase alpha (CK)(EC 2.7.1.32)(CHETK-alpha)(Ethanolamine kinase;)(EK)(EC NM_017127 29194 2.057 Chka 2.7.1.82) [Source:UniProtKB/Swiss-Prot;Acc:Q01134] XM_001076309 29376 2.060 Irs2 insulin receptor substrate 2 [Source:RefSeq peptide;Acc:NP_001162104] High mobility group protein B2 (High mobility group protein 2)(HMG-2) XM_573903 29395 2.317 Hmgb2 [Source:UniProtKB/Swiss-Prot;Acc:P52925] Eotaxin Precursor (C-C motif chemokine 11)(Small-inducible cytokine NM_019205 29397 2.766 Ccl11 A11)(Eosinophil chemotactic protein) [Source:UniProtKB/Swiss-Prot;Acc:P97545] Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 NM_017206 29464 2.376 Slc6a6 member 6) [Source:UniProtKB/Swiss-Prot;Acc:P31643] Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage-gated NM_031601 29717 2.263 Cacna1g calcium channel subunit alpha Cav3.1) [Source:UniProtKB/Swiss- Acetylcholinesterase collagenic tail peptide Precursor (AChE Q NM_019274 29755 2.424 Colq subunit)(Acetylcholinesterase-associated collagen) [Source:UniProtKB/Swiss- Prot;Acc:O35167] Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride NM_019345 54300 2.076 Slc12a3 cotransporter)(Na-Cl symporter) [Source:UniProtKB/Swiss-Prot;Acc:P55018] Urea transporter 2 (Urea transporter, kidney)(Solute carrier family 14 member 2) NM_019347 54302 2.328 Slc14a2 [Source:UniProtKB/Swiss-Prot;Acc:Q62668] Prostatic acid phosphatase Precursor (EC 3.1.3.2) [Source:UniProtKB/Swiss- NM_020072 56780 2.377 Acpp Prot;Acc:P20646] Coagulation factor XIII A chain Precursor (Coagulation factor XIIIa)(EC NM_021698 60327 2.336 F13a1 2.3.2.13)(Protein-glutamine gamma-glutamyltransferase A chain)(Transglutaminase A chain) [Source:UniProtKB/Swiss-Prot;Acc:O08619] NM_022586 60337 2.760 Npff neuropeptide FF-amide peptide precursor [ Rattus norvegicus ] NM_022216 60667 2.035 Gpr20 G protein-coupled receptor 20 [ Rattus norvegicus ] Insulin-induced gene 1 protein (INSIG-1)(Insulin-induced growth response protein NM_022392 64194 2.722 Insig1 CL-6)(Immediate-early protein CL-6) [Source:UniProtKB/Swiss-Prot;Acc:Q08755] Prolactin-inducible protein homolog Precursor (Prolactin-induced protein) NM_022708 64673 2.086 Pip [Source:UniProtKB/Swiss-Prot;Acc:O70417] Complexin-1 (Complexin I)(CPX I)(Synaphin-2) [Source:UniProtKB/Swiss- NM_022864 64832 2.013 Cplx1 Prot;Acc:P63041] NM_031699 65129 4.058 Cldn1 Claudin-1 [Source:UniProtKB/Swiss-Prot;Acc:P56745] leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), NM_031713 65146 2.024 Lilrb3 member 3 [Source:RefSeq peptide;Acc:NP_113901] NM_023985 78969 2.114 Trib1 tribbles homolog 1 [Source:RefSeq peptide;Acc:NP_076475] NM_031016 81645 2.866 Chrm2 Muscarinic acetylcholine receptor M2 [Source:UniProtKB/Swiss- Fatty acid desaturase 2 (EC 1.14.19.-)(Delta(6) fatty acid desaturase)(Delta(6) NM_031344 83512 2.191 Fads2 desaturase)(D6D) [Source:UniProtKB/Swiss-Prot;Acc:Q9Z122] Cytokine-inducible SH2-containing protein Fragment (CIS)(CIS-1)(Suppressor of XM_001074104 83681 3.877 Cish cytokine signaling)(SOCS) [Source:UniProtKB/Swiss-Prot;Acc:O70512] NM_032074 84021 2.029 Irs3 insulin receptor substrate 3 [Source:RefSeq peptide;Acc:NP_114463] XM_001062733 84380 2.039 Dhh desert hedgehog [Source:RefSeq peptide;Acc:NP_445819] XM_001055504 84407 2.312 Cdh11 cadherin 11 [Source:RefSeq peptide;Acc:NP_445844] Sodium/potassium/calcium exchanger 2 Precursor (Na(+)/K(+)/Ca(2+)-exchange NM_031743 84550 2.231 Slc24a2 protein 2)(Retinal cone Na-Ca+K exchanger) [Source:UniProtKB/Swiss- Prot;Acc:O54701] Peroxisomal membrane protein 11A (Peroxin-11A)(Peroxisomal biogenesis factor 11A)(Protein PEX11 homolog alpha)(PEX11-alpha)(RnPEX11p)(28 kDa peroxisomal NM_053487 85249 2.040 Pex11a integral membrane protein)(PMP28)(Peroxisomal membrane protein 26)(Pmp26p)(Peroxisomal coatomer /.../ NM_053549 89811 2.184 Vegfb vascular endothelial growth factor B [Source:RefSeq peptide;Acc:NP_446001] NM_053551 89813 4.762 Pdk4 pyruvate dehydrogenase kinase, isozyme 4 Ephrin-A1 Precursor (EPH-related receptor tyrosine kinase ligand 1)(LERK- NM_053599 94268 2.213 Efna1 1)(Immediate early response protein B61) [Contains Ephrin-A1, secreted form] [Source:UniProtKB/Swiss-Prot;Acc:P97553] Nuclear protein 1 (Protein p8)(Candidate of metastasis 1) NM_053611 113900 3.571 Nupr1 [Source:UniProtKB/Swiss-Prot;Acc:O54842] P2X purinoceptor 5 (P2X5)(ATP receptor)(Purinergic receptor) NM_080780 113995 2.239 P2rx5 [Source:UniProtKB/Swiss-Prot;Acc:P51578] doublesex and mab-3 related transcription factor 1 [Source:RefSeq NM_053706 114498 2.053 Dmrt1 peptide;Acc:NP_446158] Nuclear factor interleukin-3-regulated protein (E4 promoter-binding protein 4) NM_053727 114519 3.104 Nfil3 [Source:UniProtKB/Swiss-Prot;Acc:Q6IMZ0] Alpha-1B-glycoprotein Precursor (Alpha-1-B glycoprotein)(Liver regeneration- NM_022258 140656 2.134 A1bg related protein 1)(C44) [Source:UniProtKB/Swiss-Prot;Acc:Q9EPH1] Tumor necrosis factor receptor superfamily member 1B Precursor (Tumor necrosis factor receptor 2)(TNF-R2)(Tumor necrosis factor receptor type II)(TNF- NM_130426 156767 2.171 Tnfrsf1b RII)(TNFR-II)(p75)(p80 TNF-alpha receptor)(CD120b antigen) [Source:UniProtKB/Swiss-Prot;Acc:Q80WY6] NM_130752 170580 3.388 Fgf21 fibroblast growth factor 21 [Source:RefSeq peptide;Acc:NP_570108] Fibroblast growth factor 12 (FGF-12)(Fibroblast growth factor homologous factor NM_130814 170630 2.048 Fgf12 1)(FHF-1) [Source:UniProtKB/Swiss-Prot;Acc:P61150] Olfactory receptor 51E2 (Olfactory receptor 59)(G-protein coupled receptor RA1c) NM_173293 170816 2.200 Olr59 [Source:UniProtKB/Swiss-Prot;Acc:O88628] Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium NM_133610 171146 3.301 Kcnh5 channel subunit Kv10.2)(Ether-a-go-go potassium channel 2)(rEAG2) [Source:UniProtKB/Swiss-Prot;Acc:Q9EPI9] NM_134418 171459 2.269 Gp2 glycoprotein 2 (zymogen granule membrane) [ Rattus norvegicus ] NM_001007605 192239 2.443