GENITOURINARY TRACT INFECTIONS Please supplement and learn theory on the basis of the lecture, Mim’s book and supplementary materials before class!!! INTRODUCTION GENITOURINARY TRACT INFECTIONS NORMAL FLORA URETHRA Anterior of urethra Urethra Sparse: ………………………………………………………. ………………………………………………………. …………………………………………………..…. ………………………………………………………. …………………………………………………..…. ……………………………………………………………………………… ………………………………………………………. ……………………………………………………………………………….. Internal organs such as testis, ovary etc. Male urethra is relatively are sterile in healthy individuals sterile than female urethra NORMAL FLORA of VAGINA Normal flora of vagina depends upon …………………………………………………………………………………..….. VAGINA After puberty and before menopause Before puberty and after menopause ……………………………………………………………………………………………………….. …………………………………………………………………………………………………………… ………………………………………………………………………………………………………… …………………………………………………………………………………………………………… ………………………………………………………………………………………………………… …………………………………………………………………………………………………………… ………………………………………………………………………………………………………… …………………………………………………………………………………………………………… ……………………………………………………………………………………………………….. …………………………………………………………………………………………………………… ………………………………………………………………………………………………………… …………………………………………………………………………………………………………… ………………………………………………………………………………………………………… ……………………………………………………………………………………………………………. …………………………………………………………………………………………………………. ……………………………………………………………………………………………………………. 1 GENITOURINARY TRACT INFECTIONS ACUTE MANIFESTATION OF STD ……………………………………………………………. ……………………………………………………………. ………………………………………………………… ………………………………………………………. ………………………………………………………… ………………………………………………………….. ………………………………………………………… ………………………………………………………… ………………………………………………………… ……………………………………………………….. …………………………………………………………. ………………………………………………………………………… …………………………………………………………………………… ………………………………………………………………………… …………………………………………………………………………… ………………………………………………………………………… …………………………………………………………………………… ………………………………………………………………………… …………………………………………………………………………… ………………………………………………………………………… …………………………………………………………………………… ………………………………………………………………………… …………………………………………………………………………… ………………………………………………………………………… …………………………………………………………………………… ……………………………………………………………………… ……………………………………………………………………….. STUDENT NOTES -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- 2 GENITOURINARY TRACT INFECTIONS Vaginosis vs vaginitis VAGINOSIS may lead to VAGINITIS ……………………………………………………………. …………………………………………………………… Etiology But similar symptoms: Etiology ………………………………………………………… …………………………………………………………… …………………………………………………………… ………………………………………………………… …………………………………………………………… …………………………………………………………… ………………………………………………………… ………………………………………………………….. …………………………………………………………… ………………………………………………………… ………………………………………………………… ………………………………………………………… ………………………………………………………… ………………………………………………………… ………………………………………………………… ……………………………………………………….. STUDENT NOTES -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------ -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- -------------------------------------------------------------------------------------------------------------------------- 3 GENITOURINARY TRACT INFECTIONS Figure. Cytology indicating inflammation (multiple PMN cells visible) GENITOURINARY TRACT INFECTIONS DISEASE ETIOLOGY Bacteria Syphilis Gonorrhea Lymphogranuloma venereum (LGV) Granuloma inguinale (donovanosis) Chancroid Viruses Genital herpes Anogenital warts, anogenital cancer Fungi Candidiasis Parasites Trichomoniasis Other diseases caused by many different microorganisms Vaginosis Cervicitis Nongonococcal urethritis NGU Balantitis Epididymitis Proctitis, proctolitis 4 GENITOURINARY TRACT INFECTIONS DIAGNOSIS SYPHILIS Microscopy a) Dark-field microscopy – observation of alive treponames in inflammatory exudate taken