Supplementary material Ann Rheum Dis Bone Marrow-Derived CD34+ cells from 'Sle.Female Patients vs Healthy.Female Donors' (|FC|1.5, FDR<0.05) Gene name logFC logCPM LR PValue FDR COL1A1 -7.783555039 6.807948902 105.2890103 1.0556E-24 1.88393E-20 COL1A2 -6.171009777 6.297502952 51.59612708 6.81759E-13 6.08368E-09 LINC00926 -3.425625643 4.621795357 45.20797906 1.77182E-11 1.05405E-07 SLC1A7 -5.739061727 -1.873836966 37.23229183 1.04863E-09 4.67872E-06 GNLY -4.550123694 4.959247236 32.27531241 1.33803E-08 4.07216E-05 COL6A2 -2.661472883 3.98262692 31.71192942 1.7882E-08 4.07216E-05 MYBL1 -3.098929193 3.266745415 31.67503801 1.8225E-08 4.07216E-05 PF4V1 -4.829460868 3.456100153 31.55971105 1.93401E-08 4.07216E-05 CHAD -3.682939822 1.489866302 31.44326474 2.05354E-08 4.07216E-05 SEMA5A -5.237303552 0.029311815 31.14853681 2.39019E-08 4.26578E-05 BANK1 -2.525501239 5.664650031 30.61471378 3.14698E-08 5.10583E-05 EML6 -2.790461194 3.052626974 30.00141922 4.3173E-08 6.42091E-05 BMP3 -5.70889881 0.40719158 29.09759906 6.88222E-08 9.44823E-05 ZNF683 -4.551465428 0.922803558 28.15067825 1.12228E-07 0.000143067 FCER2 -2.985682471 2.351723102 25.62743279 4.1411E-07 0.000492708 PRSS23 -2.932491066 1.977294958 24.79076972 6.39027E-07 0.000706438 B3GAT1 -4.108384954 0.288279346 24.69118999 6.72911E-07 0.000706438 CHRNA2 -4.109971692 1.756332608 24.37074336 7.94664E-07 0.00078791 RAMP3 -4.778158161 2.49449499 24.22766171 8.55941E-07 0.000803999 CDHR3 -4.804214053 -0.586993167 24.0953193 9.16829E-07 0.000818132 CDH15 -4.209004979 -1.158267325 23.29288277 1.39114E-06 0.001119477 NFATC4 -2.973596063 1.26784954 23.27360628 1.40515E-06 0.001119477 PLCH2 -3.362229474 2.049290953 23.11783731 1.52371E-06 0.001119477 PRKCG -3.719676026 -1.125375997 23.08003487 1.55396E-06 0.001119477 IL12RB2 2.739935292 4.295646421 22.99615574 1.62326E-06 0.001119477 RASAL1 -4.62295634 0.642948189 22.98714266 1.63088E-06 0.001119477 MYO3A -4.874113595 -2.146246618 22.86522286 1.73768E-06 0.001131571 FUNDC2P2 -6.630545848 -2.664838955 22.76547388 1.83024E-06 0.001131571 ROR1 -4.039715176 -1.333058825 22.71673608 1.87726E-06 0.001131571 IKZF3 -3.481444988 4.118303532 22.69145306 1.90212E-06 0.001131571 TNFRSF13C -2.952505037 2.153230869 22.5242357 2.07509E-06 0.001168075 PROX1 -5.801496893 -2.283905094 22.50646062 2.09438E-06 0.001168075 DUSP8 -3.36950857 1.503366136 22.36059577 2.25963E-06 0.001222048 HGF 2.317265393 5.119296562 22.08687095 2.60586E-06 0.001367846 TBX21 -3.691187502 2.166670279 21.96696708 2.77384E-06 0.001414419 PEG10 -3.937784075 1.130357219 21.86990061 2.91775E-06 0.001446474 PRF1 -3.424784051 4.152519847 21.71834046 3.15758E-06 0.001510349 TSPYL2 -1.735509454 5.957734409 21.57338095 3.40546E-06 0.001510349 MIR378I -2.955264611 -0.138057755 21.5524929 3.44275E-06 0.001510349 NMUR1 -3.101724947 1.014206031 21.53962563 3.46593E-06 0.001510349 ZNF365 -4.394702806 -0.555464426 21.53751983 3.46973E-06 0.001510349 LOC339862 8.073309703 0.649792475 21.40526808 3.71748E-06 0.001579665 FGFBP2 -3.793215027 2.648232161 21.30832658 3.91029E-06 0.001622954 COL19A1 -4.74237519 0.991960166 21.23412428 4.06463E-06 0.00164867 MS4A1 -3.781701734 5.581634025 20.98978397 4.61739E-06 0.001818844 CTTN -3.059739138 6.651853017 20.93538199 4.75039E-06 0.001818844 FCRL3 -4.169144684 2.853695546 20.91950701 4.78992E-06 0.001818844 Grigoriou M, et al. Ann Rheum Dis 2019;0:1–12. doi: 10.1136/annrheumdis-2019-215782 Supplementary material Ann Rheum Dis MDM1 -1.674103801 6.265350757 20.8660647 4.92544E-06 0.00183134 ITPKB -1.689843315 6.260344445 20.67315048 5.44745E-06 0.001984096 C15orf52 -2.190978921 5.005076224 20.53014272 5.86996E-06 0.002095222 COL13A1 -5.329088942 -1.367454143 20.42330735 6.20692E-06 0.002150255 NBPF15 -2.558491003 2.362329638 20.40545363 6.2651E-06 0.002150255 PDZD4 -3.677589754 2.415113811 20.29553304 6.63553E-06 0.002221201 LOC100129973 -3.19508909 0.890799482 20.2711236 6.72073E-06 0.002221201 GZMH -4.015328586 2.802823968 20.1965574 6.98786E-06 0.002267496 LINC00494 -3.647518409 0.64539626 19.84213503 8.41081E-06 0.002641004 NCR3 -2.971892414 0.660488406 19.83667313 8.43487E-06 0.002641004 ALOX12 -2.466070116 5.339478818 19.7799544 8.68892E-06 0.00267364 NDNL2 -1.747363144 4.740729846 19.66956224 9.2056E-06 0.002784617 PYHIN1 -3.548590346 2.015229741 19.50472243 1.00351E-05 0.002885862 OR7A5 -4.26670234 -0.443120272 19.45454282 1.03023E-05 0.002885862 SLC27A6 7.289125602 0.049362794 19.42979556 1.04366E-05 0.002885862 PLCG1 -1.975154646 5.223519532 19.42664322 1.04538E-05 0.002885862 IRF4 -2.801993164 5.215352451 19.40412663 1.05778E-05 0.002885862 LAT -2.412226767 6.174090248 19.3960497 1.06227E-05 0.002885862 ANKRD30B -5.23764821 -2.269791091 19.36705492 1.07852E-05 0.002885862 MYBPC2 -2.889735425 -0.701421766 19.35844496 1.08339E-05 0.002885862 LINC01588 -3.096390366 1.218301238 19.24976308 1.14685E-05 0.003009965 FAM102A -2.093306829 4.680902337 19.19506986 1.18018E-05 0.003052363 RGS9 -3.461757785 0.968301019 19.16772413 1.19721E-05 0.003052363 ZNF831 -3.49312615 2.50454107 19.08729741 1.24873E-05 0.003114213 CD247 -3.522006994 3.596359401 19.07566937 1.25636E-05 0.003114213 LINC00377 -4.515787672 -2.417949807 18.97458061 1.32472E-05 0.003238658 ARL4C -2.263248559 6.196650409 18.69409693 1.53457E-05 0.003666238 BLK -3.359709559 3.534024458 18.68649909 1.5407E-05 0.003666238 SPTBN5 -2.744671969 1.983148496 18.62046839 1.59499E-05 0.003745495 PCOLCE -2.748249833 2.424609309 18.57233375 1.63577E-05 0.003791385 MECOM 2.931335783 4.185467839 18.4887316 1.70912E-05 0.003910594 CCDC92 -1.763423706 4.789172255 18.45780616 1.73708E-05 0.003924258 MIR4697HG -3.105109133 1.814192656 18.37808236 1.8113E-05 0.004010714 SMTN -1.999033916 4.974989388 18.36864019 1.82029E-05 0.004010714 SIDT1 -1.839722123 4.113630665 18.28965345 1.89735E-05 0.004043046 NEXN -2.659630769 4.855653804 18.28626251 1.90073E-05 0.004043046 ASAP2 -2.057859281 5.507765908 18.28405835 1.90293E-05 0.004043046 KLHL31 7.176711797 -0.275373704 18.17548249 2.01456E-05 0.004221914 KLHL14 -3.465069201 1.679043891 18.15259601 2.03891E-05 0.004221914 VEGFC -3.12165981 2.368978247 18.12119066 2.07282E-05 0.004221914 LINC01515 5.136633906 0.46567113 18.11301054 2.08174E-05 0.004221914 ATP13A4 -3.191307043 2.81401811 18.03116018 2.17319E-05 0.004357848 RASA3 -1.735085246 6.716744243 17.99975892 2.20933E-05 0.0043811 TGFBR3 -2.849075818 3.573523848 17.95627945 2.26037E-05 0.004433067 CLIC3 -2.78383072 0.705058453 17.92413065 2.29888E-05 0.004459574 MIAT -2.670916648 5.641785905 17.78617883 2.47172E-05 0.004743315 SPOCK2 -3.174474269 5.597972132 17.6617751 2.63877E-05 0.005010005 LOC101929125 -4.107240653 -0.705001296 17.6346692 2.67664E-05 0.005023754 SNCA -1.647117615 6.084915133 17.60130513 2.72401E-05 0.005023754 CHI3L2 -2.872277114 0.832877595 17.56119001 2.78209E-05 0.005023754 KIAA1407 -1.75374272 3.567051094 17.52441678 2.83642E-05 0.005023754 Grigoriou M, et al. Ann Rheum Dis 2019;0:1–12. doi: 10.1136/annrheumdis-2019-215782 Supplementary material Ann Rheum Dis DNM3 -2.564681489 5.55200133 17.51982592 2.84327E-05 0.005023754 ALS2CL -2.125990855 3.375677547 17.51677609 2.84784E-05 0.005023754 C1orf95 -2.854280961 2.707968035 17.50567903 2.86451E-05 0.005023754 SLC35D3 -3.260366451 3.001945043 17.50124278 2.8712E-05 0.005023754 ADAMTS17 -3.140720227 0.181698234 17.47151729 2.91644E-05 0.005053378 FCRLA -2.690625782 2.856370354 17.36106075 3.09094E-05 0.005288892 NETO1 -4.823124443 -1.282012996 17.34061328 3.12438E-05 0.005288892 IL21R -3.066975475 1.824282859 17.3303652 3.14127E-05 0.005288892 S1PR5 -3.726083572 2.271746216 17.30800081 3.17846E-05 0.005301489 DAAM1 -2.022641248 6.530945031 17.22538356 3.31971E-05 0.005485821 DNAAF3 -3.156557524 2.107632268 17.19756526 3.36868E-05 0.00551567 APBB2 -2.186274075 2.677012184 17.16194121 3.43245E-05 0.005568991 FYN -1.709948973 6.084316456 17.12204004 3.50532E-05 0.005578338 VSIG2 -2.725861634 3.061089488 17.11625737 3.516E-05 0.005578338 EYA1 -3.757763414 -0.39976954 17.10764833 3.53198E-05 0.005578338 RORA -3.061343245 4.34597913 17.04528917 3.64988E-05 0.005713984 SERPINE1 -3.200236954 5.269219266 16.98864727 3.7604E-05 0.005730792 PRRT2 -2.736551412 0.878302448 16.97530919 3.78691E-05 0.005730792 XYLT2 -1.856016685 5.135154352 16.97489536 3.78774E-05 0.005730792 BCL9L -2.001573929 5.105764248 16.97423172 3.78906E-05 0.005730792 RHD -3.209765063 3.005200395 16.95236647 3.83295E-05 0.00574846 INHBA-AS1 -3.472547539 1.116304598 16.90933735 3.92082E-05 0.005816822 GNAZ -2.963628425 5.218404855 16.89828569 3.94372E-05 0.005816822 MARK1 -3.69814587 -1.397414216 16.83843251 4.07006E-05 0.005929487 BIRC3 -1.845710156 5.728491879 16.83076005 4.08655E-05 0.005929487 GP9 -2.957026874 5.778547467 16.79317033 4.16831E-05 0.005999334 CD6 -3.261089291 4.267213679 16.73281278 4.30303E-05 0.006100223 TC2N -2.141758697 5.502263772 16.72636142 4.31769E-05 0.006100223 CPE -3.926497019 0.09691135 16.70161307 4.37438E-05 0.006100223 PARP15 -1.89305251 5.300731916 16.7012896 4.37512E-05 0.006100223 PRKCA -2.030823907 4.622774157 16.61700251 4.57391E-05 0.006245472 CDCP1 2.84457411 3.489482648 16.61585704 4.57668E-05 0.006245472 EXOC3L4 -2.776349754 3.145685503 16.6102646 4.59019E-05 0.006245472 CAMK2D -2.143379717 3.394324612 16.59558133 4.62587E-05 0.006245472 ADAM12 -2.867938447 -0.005684569 16.58397173 4.65427E-05 0.006245472 CBLN3 -2.822449949 0.992896065 16.55676495 4.72152E-05 0.006288437 GNB5 -2.030220931 5.509333141 16.45555316 4.98041E-05 0.006584099 MYO3B -3.430052643 -1.324071464 16.34252158 5.28644E-05 0.00693728 OSBPL10 -2.663354409 1.780451879 16.27020899