MARCH 2019 AJNR VOLUME 40 • PP 387–582 MARCH 2019 THE JOURNAL OF DIAGNOSTIC AND VOLUME 40 INTERVENTIONAL NEURORADIOLOGY NUMBER 3 WWW.AJNR.ORG Whole-brain microscopy discrimination of subcortical anatomy Imaging of patients with suspected large-vessel occlusion at primary stroke centers Endovascular treatment of unruptured MCA bifurcation aneurysms regardless of aneurysm morphology Official Journal ASNR • ASFNR • ASHNR • ASPNR • ASSR AMERICAN JOURNAL OF NEURORADIOLOGY MARCH 2019 Publication Preview at www.ajnr.org features articles released in advance of print. AJNRVOLUME 40 Visit www.ajnrblog.org to comment on AJNR content and chat with colleagues NUMBER 3 and AJNR’s News Digest at http://ajnrdigest.org to read the stories behind the WWW.AJNR.ORG latest research in neuroimaging. 387 PERSPECTIVES B. Thomas REVIEW ARTICLE 388 Understanding Subdural Collections in Pediatric Abusive Head Trauma PEDIATRICS D. Wittschieber, et al. PRACTICE PERSPECTIVES 396 Imaging of Patients with Suspected Large-Vessel Occlusion at Primary Stroke Centers: Available Modalities and a Suggested Approach M.A. Almekhlafi, et al. GENERAL CONTENTS 401 3T MRI Whole-Brain Microscopy Discrimination of Subcortical ADULT BRAIN Anatomy, Part 1: Brain Stem M.J. Hoch, et al. 408 Dynamic Contrast-Enhanced MRI Reveals Unique Blood-Brain Barrier ADULT BRAIN Permeability Characteristics in the Hippocampus in the Normal Brain FUNCTIONAL J. Ivanidze, et al. 412 Disorder in Pixel-Level Edge Directions on T1WI Is Associated with the ADULT BRAIN Degree of Radiation Necrosis in Primary and Metastatic Brain Tumors: FUNCTIONAL Preliminary Findings P. Prasanna, et al. 418 Accurate Patient-Specific Machine Learning Models of Glioblastoma ADULT BRAIN Invasion Using Transfer Learning L.S. Hu, et al. FUNCTIONAL 426 Neuroimaging-Based Classification Algorithm for Predicting 1p/19q- ADULT BRAIN Codeletion Status in IDH-Mutant Lower Grade Gliomas P.P. Batchala, et al. 433 Preoperative MR Imaging to Differentiate Chordoid Meningiomas from ADULT BRAIN Other Meningioma Histologic Subtypes J.D. Baal, et al. 440 Improved Detection of Subtle Mesial Temporal Sclerosis: Validation of ADULT BRAIN a Commercially Available Software for Automated Segmentation of Hippocampal Volume J.M. Mettenburg, et al. 446 A Serial 10-Year Follow-Up Study of Atrophied Brain Lesion Volume and ADULT BRAIN Disability Progression in Patients with Relapsing-Remitting MS R. Zivadinov, et al. AJNR (Am J Neuroradiol ISSN 0195–6108) is a journal published monthly, owned and published by the American Society of Neuroradiology (ASNR), 800 Enterprise Drive, Suite 205, Oak Brook, IL 60523. Annual dues for the ASNR include $170.00 for journal subscription. The journal is printed by Cadmus Journal Services, 5457 Twin Knolls Road, Suite 200, Columbia, MD 21045; Periodicals postage paid at Oak Brook, IL and additional mailing offices. Printed in the U.S.A. POSTMASTER: Please send address changes to American Journal of Neuroradiology, P.O. Box 3000, Denville, NJ 07834, U.S.A. Subscription rates: nonmember $410 ($480 foreign) print and online, $320 online only; institutions $470 ($540 foreign) print and basic online, $935 ($1000 foreign) print and extended online, $380 online only (basic), extended online $825; single copies are $35 each ($40 foreign). Indexed by PubMed/Medline, BIOSIS Previews, Current Contents (Clinical Medicine and Life Sciences), EMBASE, Google Scholar, HighWire Press, Q-Sensei, RefSeek, Science Citation Index, SCI Expanded, Meta/CZI and ReadCube. Copyright © American Society of Neuroradiology. 453 Aqueductal CSF Stroke Volume Is Increased in Patients with Idiopathic ADULT BRAIN Normal Pressure Hydrocephalus and Decreases after Shunt Surgery J. Shanks, et al. 460 Quantitative Susceptibility Mapping to Assess Cerebral Vascular ADULT BRAIN Compliance C. Birkl, et al. 464 Acute and Evolving MRI of High-Altitude Cerebral Edema: Microbleeds, ADULT BRAIN Edema, and Pathophysiology P.H. Hackett, et al. 470 Alterations in Blood-Brain Barrier Permeability in Patients with ADULT BRAIN Systemic Lupus Erythematosus J.M. Chi, et al. 478 Longitudinal White Matter Changes following Carbon Monoxide ADULT BRAIN Poisoning: A 9-Month Follow-Up Voxelwise Diffusional Kurtosis Imaging FUNCTIONAL Study M.-C. Chou, et al. 483 Focal Hypoperfusion in Acute Ischemic Stroke Perfusion CT: Clinical ADULT BRAIN and Radiologic Predictors and Accuracy for Infarct Prediction O. Bill, et al. 490 Complementary Roles of Dynamic Contrast-Enhanced MR Imaging and ADULT BRAIN Postcontrast Vessel Wall Imaging in Detecting High-Risk Intracranial INTERVENTIONAL Aneurysms H. Qi, et al. 497 Flow-Diversion Treatment of Unruptured Saccular Anterior INTERVENTIONAL Communicating Artery Aneurysms: A Systematic Review and Meta-Analysis F. Cagnazzo, et al. 503 Endovascular Treatment of Unruptured MCA Bifurcation Aneurysms INTERVENTIONAL Regardless of Aneurysm Morphology: Short- and Long-Term Follow-Up F. Hagen, et al. 510 Local Hemodynamic Conditions Associated with Focal Changes in the INTERVENTIONAL Intracranial Aneurysm Wall J.R. Cebral, et al. 517 Aneurysm Characteristics, Study Population, and Endovascular INTERVENTIONAL Techniques for the Treatment of Intracranial Aneurysms in a Large, Prospective, Multicenter Cohort: Results of the Analysis of Recanalization after Endovascular Treatment of Intracranial Aneurysm Study M. Gawlitza, et al. 524 Comparison of Pipeline Embolization Device Sizing Based on INTERVENTIONAL Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study J.M. Ospel, et al. 531 Commentary Pipeline Sizing Based on Computer Simulation T. Becske 533 Predictors and Clinical Impact of Delayed Stent Thrombosis after INTERVENTIONAL Thrombectomy for Acute Stroke with Tandem Lesions R. Pop, et al. 540 Validating the Automatic Independent Component Analysis of DSA INTERVENTIONAL J.-S. Hong, et al. 543 CT Texture Analysis of Cervical Lymph Nodes on Contrast-Enhanced HEAD & NECK [18F] FDG-PET/CT Images to Differentiate Nodal Metastases from Reactive Lymphadenopathy in HIV-Positive Patients with Head and Neck Squamous Cell Carcinoma H. Kuno, et al. 551 Etiology-Specific Mineralization Patterns in Patients with Labyrinthitis HEAD & NECK Ossificans K. Buch, et al. 558 Diagnostic Utility of Optic Nerve Measurements with MRI in Patients HEAD & NECK with Optic Nerve Atrophy B. Zhao, et al. 562 Infant Midnasal Stenosis: Reliability of Nasal Metrics M.E. Graham, et al. PEDIATRICS HEAD & NECK 568 Evaluation of the Implementation of the Response Assessment in PEDIATRICS Neuro-Oncology Criteria in the HERBY Trial of Pediatric Patients with Newly Diagnosed High-Grade Gliomas D. Rodriguez, et al. 576 Underdevelopment of the Human Hippocampus in Callosal Agenesis: PEDIATRICS An In Vivo Fetal MRI Study V. Knezovic´, et al. 582 35 YEARS AGO IN AJNR ONLINE FEATURES MEMORIAL E12 Robert H. Ackerman, MD, MPH M.H. Lev, et al. LETTERS E14 Engorged Medullary Veins in Neurosarcoidosis: A Reflection of Underlying Phlebitis? G. Bathla, et al. E16 Reply C. Zamora, et al. E17 High-Resolution Vessel Wall MR Imaging as an Alternative to Brain Biopsy D.G. Correˆa, et al. BOOK REVIEWS R.M. Quencer, Section Editor Please visit www.ajnrblog.org to read and comment on Book Reviews. Demonstration of the dentatorubrothalamic tract within the superior cerebellar peduncle and rostral brain stem. Top left, Axial caudal midbrain image angled 10° anterosuperior to posteroinferior relative to the ACPC plane demonstrates the tract traveling the midbrain to reach the decussation. Top right, Coronal oblique image that is perpendicular to the long axis of the hippocampus at the level of the ventral superior cerebellar decussation shows a component of the dentatorubrothalamic tract arising from the cerebellar dentate nucleus, ascending via the superior cerebellar peduncle to the decussation, and then enveloping the contralateral red nucleus. Bottom, Parasagittal image shows the relatively long anteroposterior dimension of this tract, which becomes Indicates Editor’s Indicates Fellows’ Indicates open access to non- Indicates article with less compact and Choices selection Journal Club selection subscribers at www.ajnr.org supplemental on-line table distinct as it ascends Indicates article with Indicates article with Evidence-Based Evidence-Based toward the thalamus. supplemental on-line photo supplemental on-line video Medicine Level 1 Medicine Level 2 ® Aneurysm Therapy LVIS Solutions Intraluminal Support Device The first and only stent with Premarket Approval (PMA) for use in stent-assisted coil embolization Stent Deployment. Refined. Braided Coil Assist Stents with High Neck Coverage, Excellent Visibility and Improved Conformability* Low-profile Visualized Intraluminal Support INDICATIONS FOR USE: The LVIS® and LVIS® Jr. devices are indicated for use with neurovascular embolization coils in patients ≥ 18 years of age for the treatment of wide-neck (neck width ≥ 4 mm or dome to neck ratio < 2) saccular intracranial aneurysms arising from a parent vessel with a diameter ≥ 2.0 mm and ≤ 4.5 mm. Rx Only: Federal (USA) law restricts this device to sale by or on the order of a physician. The HydroCoil® Embolic System (HES) and MicroPlex® Coil System (MCS) are intended for the endovascular embolization of intracranial aneurysms and other neurovascular abnormalities such as arteriovenous malformations and arteriovenous fistulae. The HES and MCS are also intended for vascular occlusion of blood vessels within the neurovascular system to permanently obstruct blood flow