1. Indicate the mechanism of broncholytic action of Ipratropii D. Glaucinum. bromidum: E. Falimint. A. Myotropic influence. B. Blockade of M-cholinoceptors. 9. Indicate the drug oppressing a peripheral link of cough C. Stimulation of -receptors. reflex: D. Inhibition of phosphodiasterase. A. Atropini sulfas. E. Activation of adenilatcyclase. B. Codeini phosphas. C. Ethylmorphini hydrochloridum. 2. Indicate the mechanism of bronchodilator – Salbutamolum D. Bromhexinum. action: E. Libexinum. A. Stimulation of 2-receptors. B. Stimulation of -receptors. 10. The mechanism of expectorant action of Thermopsis herb infusion is: C. Inhibition of 2-receptors. D. Inhibition of phosphodiasterase. A. Irritates bronchial glands during excretion that leads to E. Blockade of adenosine receptors. stimulation of their secretion. B. Directly stimulates peristalsis of bronchial smooth 3. Indicate the stimulant of respiration with sedative effect and muscles. anti-inflammatory properties: C. It destroys proteins of sputum. A. Bemegridum. D. It stimulates bronchial secretion reflexively irritating B. Aethimizolum. the stomach receptors. C. Coffeinum-natrii benzoas. E. It inhibits the cough center. D. Cordiaminum. E. Lobelini hydrochloridum. 11. Indicate an expectorant agent possessing the reflex type of action: 4. Indicate the antitussive agent with central non-narcotic type A. Bromhexinum. of action: B. Infusum herbae Thermopsidis. A. Codeini phosphas. C. Acetylcysteinum. B. Aethylmorphini hydrochloridum. D. Trypsinum. C. Libexinum. E. Kalii iodidum. D. Oxeladini citras. E. Bromhexinum. 12. Mark the group of drugs used for elimination of bronchial asthma attacks. 5. Indicate the antitussive agent of peripheral action: A. M-cholinomimetics. A. Codeini phosphas. B. N-cholinomimetics. B. Aethylmorphini hydrochloridum. C. Sympatholytics. C. Libexinum. D. Beta-adrenoblockers. D. Glaucini hydrochloridum. E. Beta-adrenomimetics. E. Bromhexinum. 13. Indicate the mechanism of broncholytic effect of 6. A child was born with asphyxia. What agent is it necessary adrenaline: to introduce for stimulation of breath? A. Blockade of -2-adrenoreceptors. A. Lidocainum. B. Stimulation of -1-adrenoreceptors. B. Lobelini hydrochloridum. C. Stimulation -2-adrenoreceptors. C. Prazosinum. D. Stimulation of -1 and -2-adrenoreceptors. D. Atropini sulfas. E. Blockade of N-cholinoreceptors. E. Proserinum. 14. Activation of what receptor formations should be produced 7. To specify an analeptic which possesses sedative activity at the patient with bronchial asthma to eliminate bronchospasm? and can be used as desensibilizing agent in bronchial A. -adrenoreceptors asthma: B. -adrenoreceptors and -adrenoreceptors A. Carbogenum. C. M-cholinoreceptors B. Camphora. D. N-cholinoreceptors C. Cordiaminum. E. -adrenoreceptors D. Aethimizolum. E. Dimedrolum. 15. What from the listed below effects of diuretics explains their effectiveness in the case of pulmonary edema? 8. Indicate antitussive agent possessing properties of opioid A. Reduce the blood pressure in the systemic circulation. analgesics: B. Reduce the excitability of respiratory center. A. Codeini phosphas. C. Increase osmotic pressure of the blood. B. Libexinum. D. Cause the blood redistribution in the organism. C. Tussuprex. E. Improve systemic hemodynamix. 1 16. Indicate the diuretic agent which should be used to treat A. Propranololum. pulmonary edema: B. Anaesthesinum. A. Spironolactonum. C. Verapamilum. B. Hydrochlorthiazidum (dichlothiazidum). D. Pananginum. C. Triamterenum. E. Lidocainum. D. Furosemidum. E. Acetazolamidum (diacarbum). 23. A patient complains of edemas, rapid pulse, short breath, cyanosis of mucous tunics. The diagnosis is chronic cardiac 17. Benzohexonium was introduced to a patient with insufficiency. What is it necessary to prescribe to the pulmonary edema caused by systemic arterial hypertension. patient? Indicate the mechanism of action of this agent? A. Mesatonum. A. Activation of -adrenoreceptors of vessels. B. Papaverini hydrochloridum. B. Blockade of dopamine receptors in the CNS. C. Digoxinum. C. Stimulation of M-cholinoreceptors. D. Cordiaminum. D. Activation of adrenoreceptors of vasomotor center. E. Nitroglycerinum. E. Blockade of N-cholinoreceptors of vegetative ganglions. 24. A patient with signs of acute cardiac insufficiency is delivered to a hospital. Which drug is it necessary to 18. A patient with bronchial asthma attack has a concomitant prescribe urgently? disease – angina pectoris. What bronchodilator is to be A. Corglyconum. prescribed in this case? B. Aethimizolum. A. Salbutamolum. C. Dithylinum. B. Adrenalini hydrochloridum. D. Piridostigmini bromidum. C. Isadrinum. E. Digitoxinum. D. Aminophyllinum. E. Atropini sulfas. 25. A patient with myocardial infarction and cardiac insufficiency has ventricular arrhythmia. What 19. A 42-year-old patient has bronchial asthma. To relieve antiarrhythmic drug is a medicine of choice in this case? the attacks of bronchospasm a doctor has prescribed A. Novocainamidum. salbutamol. What is its medical effect? B. Chinidini sulfas. A. Stimulation of 1-adrenoreceptors C. Nifedipinum. B. Stimulation of 2-adrenoreceptors D. Lidocainum. E. Aimalinum. C. Stimulation of 2-adrenoreceptors D. Blockade of 1-adrenoreceptors 26. Acute cardiovascular insufficiency is accompanied by E. Blockade of 1-adrenoreceptors edema of lungs. What medicine of cardiac glycoside group 20. Indicate the drug which is used as prophylactic agent of should be prescribed to the patient? bronchial asthma attacks: A. Acetazolamidum (Diacarbum). A. Adrenalini hydrochloridum. B. Spironolactonum. B. Euphyllinum. C. Dichlothiazidum. C. Cromolinum-sodium. D. Corglyconum. D. Aethimizolum. E. Triamterenum. E. Bromhexinum. 27. A patient with cardiogenic shock, hypotension, asthma, 21. A patient with chronic cardiovascular insufficiency during and edemas was prescribed a nonglycosidic cardiotonic. digitalization demonstrated the following symptoms: Which drug was injected to the patient? headache, fatigue, nausea, color vision impairment A. Coffeinum-natrii benzoas. (surrounding objects are perceived in green color). On B. Dobutaminum. ECG the sinus bradycardia and signs of impairment of C. Cordiaminum. atrioventricular conductivity were detected. What can be D. Aethimizolum. prescribed to relieve the symptoms of intoxication. E. Bemegridum. A. Dipiroximum. B. Naloxonum. C. Bemegridum. D. Unithiolum. E. Atropini sulfas. 22. Ventricular arrhythmia followed myocardial infarction of a patient. Cardiac rhythm was normalized by the introduction of antiarrhythmic drug with local anesthesia effect. What drug was prescribed. 2 28. A 68-year-old patient with cardiac insufficiency, who had B. Blockade of -adrenoreceptors of the myocardium. been taking Digitalis medicines for a long time, had C. Blockade of - and -adrenoreceptors of the symptoms of intoxication, which were quickly eliminated myocardium. by the application of the donator of the sulphhydric groups D. Blockade of calcium channels of the cardiomyocyte of unithiol. What is the mechanism of the therapeutic effect membranes. of this drug? E. Blockade of M-cholinoreceptors of the myocardium. A. Inhibition of potassium release from cardiac hystiocytes. B. Reduction of accumulation of ionized calcium. 34.Specify the cardiac glycoside which possesses the fastest C. Reactivation of Na/K-ATP-ase of cardiac hystiocytes onset of the action: membranes. A. Strophanthinum. D. Slowing-down of sodium coming into cardiac B. Celanidum (lanatosidum). hystiocytes. C. Digitoxinum. E. Increase of energy supply to the myocardium. D. Digoxinum. E. Adonisidum. 29. A cardiotonic drug was prescribed to a 50-year-old patient with chronic cardiac insufficiency and tachyarrhythmia. 35.What effect of cardiac glycosides is of greatest Which of these medicines was prescribed to the patient. importance? A. Dobutaminum. A. Increase of diuresis and elimination of edemas. B. Dophaminum. B. Increase of myocardium excitability. C. Digoxinum. C. Decrease of myocardium automatism. D. Amiodaronum. D. Decrease of myocardium conductivity. E. Mildronatum. E. Increase of myocardium contractility. 30. A patient with complaints of frequent pulse, dyspnea, 36.Indicate the mechanism of cardiotonic action of cardiac cyanosis of mucous tunics was hospitalized to a glycosides: cardiological department. Examination revealed edemas A. Excitation of -adrenoreceptors of myocardium. on the lower extremities, ascites. Chronic cardiac B. Activation of calcium channels of cardiomyocyte insufficiency was diagnosed. Which of the drugs should membranes. be prescribed to the patient? C. Inhibition of Na/K-ATP-ase of cardiac hystocytes A. Digitoxinum. membranes. B. Cordiaminum. D. Oppression of phosphodiesterase of cardiomyocytes. C. Adrenalini hydrochloridum. E. Activation of potassium channels of cardiomyocytes. D. Corglyconum. E. Drotaverini hydrochloridum. 37.Indicate the group of drugs which is the most expedient for treatment of paroxysmal atrial tachycardia: 31. A patient with pulmonary edema caused by acute left A. M-cholinoblockers. ventricular insufficiency patient was treated with cardiac B. Cardiac glycosides. glycoside. In 10-15 min, his condition improved and C. Na-channels blockers. maximal effect was in 1-1,5 hours, after that the action D. -adrenomimetics. gradually decreased. What drug has been injected? E. -adrenoblockers. A. Strophanthinum. B. Digoxinum. 38.Indicate the group of drugs, overdosage of which is C. Celanidum. accompanied by following signs: anorexia, nausea, vomiting,