MISSISSIPPI LEGISLATURE REGULAR SESSION 2021 By: Senator(s) Jordan, Jackson (11th), To: Drug Policy Thomas SENATE BILL NO. 2278 1 AN ACT TO AMEND SECTION 41-29-113, MISSISSIPPI CODE OF 1972, 2 TO INCLUDE ISOTONITAZENE, FLUALPRAZOLAM, FLUBROMAZEPAM, 3 FLUBROMAZOLAM AND CLONAZOLAM TO SCHEDULE I BECAUSE THESE DRUGS 4 HAVE NO LEGITIMATE MEDICAL USE AND HAVE HIGH POTENCY WITH GREAT 5 POTENTIAL TO CAUSE HARM; TO AMEND SECTION 41-29-115, MISSISSIPPI 6 CODE OF 1972, TO REVISE THE CHEMICAL NAME OF THIAFENTANIL; TO 7 AMEND SECTION 41-29-119, MISSISSIPPI CODE OF 1972, TO INCLUDE 8 BREXANOLONE AND SOLRIAMFETOL AS SCHEDULE IV CONTROLLED SUBSTANCES 9 BECAUSE THE FEDERAL DRUG ADMINISTRATION RECENTLY APPROVED THESE 10 DRUGS FOR MEDICAL USE; AND FOR RELATED PURPOSES. 11 BE IT ENACTED BY THE LEGISLATURE OF THE STATE OF MISSISSIPPI: 12 SECTION 1. Section 41-29-113, Mississippi Code of 1972, is 13 amended as follows: 14 41-29-113. 15 SCHEDULE I 16 (a) Schedule I consists of the drugs and other substances, 17 by whatever official name, common or usual name, chemical name, or 18 brand name designated, that is listed in this section. 19 (b) Opiates. Unless specifically excepted or unless listed 20 in another schedule, any of the following opiates, including their 21 isomers, esters, ethers, salts and salts of isomers, esters and S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ G1/2 21/SS26/R204.1 PAGE 1 (ens\tb) 22 ethers, whenever the existence of these isomers, esters, ethers 23 and salts is possible within the specific chemical designation: 24 (1) Acetyl-alpha-methylfentanyl; 25 (2) Acetyl Fentanyl 26 N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide; 27 (3) AH-7921 (3,4-dichloro-N-[(1-dimethylamino) 28 cyclohexylmethyl]benzamide); 29 (4) Acetylmethadol; 30 (5) Allylprodine; 31 (6) Alphacetylmethadol, except levo-alphacetylmethadol 32 (levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM); 33 (7) Alphameprodine; 34 (8) Alphamethadol; 35 (9) Alpha-methylfentanyl; 36 (10) Alpha-methylthiofentanyl; 37 (11) Benzethidine; 38 (12) Betacetylmethadol; 39 (13) Beta-hydroxyfentanyl; 40 (14) Beta-hydroxy-3-methylfentanyl; 41 (15) Betameprodine; 42 (16) Betamethadol; 43 (17) Betaprodine; 44 (18) Butyrl fentanyl 45 (N-(1-phenethylpiperidin-4-yl)-N-phenylbutyramide); 46 (19) Clonitazene; S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 2 (ens\tb) 47 (20) Dextromoramide; 48 (21) Diampromide; 49 (22) Diethylthiambutene; 50 (23) Difenoxin; 51 (24) Dimenoxadol; 52 (25) Dimepheptanol; 53 (26) Dimethylthiambutene; 54 (27) Dioxaphetyl butyrate; 55 (28) Dipipanone; 56 (29) Ethylmethylthiambutene; 57 (30) Etonitazene; 58 (31) Etoxeridine; 59 (32) Fentanyl-related substances, meaning any substance 60 not otherwise listed under another schedule and for which no 61 exemption or approval is in effect under Section 505 of the 62 Federal Food, Drug, and Cosmetic Act [21 USC 355] that is 63 structurally related to fentanyl by one or more of the following 64 modifications: 65 (A) Replacement of the phenyl portion of the 66 phenethyl group by any monocycle, whether or not further 67 substituted in or on the monocycle; 68 (B) Substitution in or on the phenethyl group with 69 alkyl, alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino or nitro 70 groups; S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 3 (ens\tb) 71 (C) Substitution in or on the piperidine ring with 72 alkyl, alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, 73 amino or nitro groups; 74 (D) Replacement of the aniline ring with any 75 aromatic monocycle whether or not further substituted in or on the 76 aromatic monocycle; and/or 77 (E) Replacement of the N-propionyl group by 78 another acyl group. 79 Fentanyl-related substances include, but are not limited to, 80 cyclopropyl fentanyl, 81 (N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopropanecarboxamide); 82 Furanyl-Fentanyl, 83 (N-(1-phenethylpiperidin-4-yl)-N-phenylfuran-2-carboxamide); 84 valeryl fentanyl, 85 (N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide); 86 para-fluorobutyryl fentanyl, 87 (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)butyramide); 88 para-methoxybutyryl fentanyl, 89 (N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl)butyramide); 90 para-chloroisobutyryl fentanyl, 91 (N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide); 92 isobutyryl fentanyl, 93 (N-(1-phenethylpiperidin-4-yl)-N-phenylisobutyramide); S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 4 (ens\tb) 94 cyclopentyl fentanyl, 95 (N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopentanecarboxamide); 96 and 97 ocfentanil, 98 (N-(2-fluorophenyl)-2-methoxy-N-(1-phenethylpiperidin-4-yl)acetami 99 de); 100 (33) Furethidine; 101 (34) Hydroxypethidine; 102 (35) Isotonitazene (N,N-diethyl-2-(2-(4 103 isopropoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan-1-amine); 104 ( * * *36) Ketobemidone (including the optical and 105 geometric isomers); 106 ( * * *37) Levomoramide; 107 ( * * *38) Levophenacylmorphan; 108 ( * * *39) 3-methylfentanyl; 109 ( * * *40) 3-methylthiofentanyl; 110 ( * * *41) Morpheridine; 111 ( * * *42) MPPP 112 (1-methyl-4-phenyl-4-propionoxypiperidine); 113 ( * * *43) 114 N-[1-[2-hydroxy-2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylprop 115 ionamide, its isomers, esters, ethers, salts and salts of isomers, 116 esters and ethers (other names: beta-hydroxythiofentanyl); 117 ( * * *44) Noracymethadol; 118 ( * * *45) Norlevorphanol; S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 5 (ens\tb) 119 ( * * *46) Normethadone; 120 ( * * *47) Norpipanone; 121 ( * * *48) Para-fluorofentanyl; 122 ( * * *49) PEPAP 123 (1-(-2-phenethyl)-4-phenyl-4-acetoxypiperidine); 124 ( * * *50) Phenadoxone; 125 ( * * *51) Phenampromide; 126 ( * * *52) Phenomorphan; 127 ( * * *53) Phenoperidine; 128 ( * * *54) Piritramide; 129 ( * * *55) Proheptazine; 130 ( * * *56) Properidine; 131 ( * * *57) Propiram; 132 ( * * *58) Racemoramide; 133 ( * * *59) Thiofentanyl; 134 ( * * *60) Tilidine; 135 ( * * *61) Trimeperidine; 136 ( * * *62) U-47700, 137 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide. 138 (c) Opium derivatives. Unless specifically excepted or 139 unless listed in another schedule, any of the following opium 140 derivatives, their salts, isomers and salts of isomers, whenever 141 the existence of these salts, isomers and salts of isomers is 142 possible within the specific chemical designation: 143 (1) Acetorphine; S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 6 (ens\tb) 144 (2) Acetyldihydrocodeine; 145 (3) Benzylmorphine; 146 (4) Codeine methylbromide; 147 (5) Codeine-N-Oxide; 148 (6) Cyprenorphine; 149 (7) Desomorphine; 150 (8) Dihydromorphine; 151 (9) Drotebanol; 152 (10) Etorphine (except hydrochloride salt); 153 (11) Heroin; 154 (12) Hydromorphinol; 155 (13) Methyldesorphine; 156 (14) Methyldihydromorphine; 157 (15) Monoacetylmorphine; 158 (16) Morphine methylbromide; 159 (17) Morphine methylsulfonate; 160 (18) Morphine-N-Oxide; 161 (19) Myrophine; 162 (20) Nicocodeine; 163 (21) Nicomorphine; 164 (22) Normorphine; 165 (23) Pholcodine; 166 (24) Thebacon. 167 (d) Hallucinogenic substances. Unless specifically excepted 168 or unless listed in another schedule, any material, compound, S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 7 (ens\tb) 169 mixture or preparation which contains any quantity of the 170 following substances, their salts, isomers (whether optical, 171 positional, or geometric) and salts of isomers, whenever the 172 existence of these salts, isomers and salts of isomers is possible 173 within the specific chemical designation: 174 (1) Alpha-ethyltryptamine; 175 (2) 4-bromo-2,5-dimethoxy-amphetamine; 176 (3) 4-bromo-2,5-dimethoxyphenethylamine; 177 (4) 2,5-dimethoxyamphetamine; 178 (5) 2,5-dimethoxy-4-ethylamphetamine (DOET); 179 (6) 2,5-dimethoxy-4-(n)-propylthiophenethylamine 180 (2C-T-7); 181 (7) 4-methoxyamphetamine; 182 (8) 5-methoxy-3,4-methylenedioxy-amphetamine; 183 (9) 4-methyl-2,5-dimethoxy-amphetamine; 184 (10) 3,4-methylenedioxy amphetamine; 185 (11) 3,4-methylenedioxymethamphetamine (MDMA); 186 (12) 3,4-methylenedioxy-N-ethylamphetamine (also known 187 as N-ethyl-alpha-methyl-3,4(methylenedioxy)phenethylamine, N-ethyl 188 MDA, MDE, MDEA); 189 (13) N-hydroxy-3,4-methylenedioxyamphetamine (also 190 known as N-hydroxy MDA, N-OHMDA, and 191 N-hydroxy-alpha-methyl-3,4(methylenedioxy)phenethylamine); 192 (14) 3,4,5-trimethoxy amphetamine; 193 (15) 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT); S. B. No. 2278 *SS26/R204.1* ~ OFFICIAL ~ 21/SS26/R204.1 PAGE 8 (ens\tb) 194 (16) Alpha-methyltryptamine (also known as AMT); 195 (17) Bufotenine; 196 (18) Diethyltryptamine; 197 (19) Dimethyltryptamine; 198 (20) 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT); 199 (21) Ibogaine; 200 (22) Lysergic acid diethylamide (LSD); 201 (23) (A) Marijuana (Hemp as defined and regulated 202 under Sections 69-25-201 through 69-25-221 and Cannabidiol 203 contained in a legend drug product approved by the Federal Food 204 and Drug Administration or obtained under Section 41-29-136 are 205 exempt under Schedule I); 206 (B) Hashish; 207 (24) Mescaline; 208 (25) Parahexyl; 209 (26) Peyote; 210 (27) N-ethyl-3-piperidyl benzilate; 211 (28) N-methyl-3-piperidyl benzilate; 212 (29) Psilocybin; 213 (30) Psilocyn; 214 (31) Tetrahydrocannabinols, meaning 215 tetrahydrocannabinols contained in a plant of the genus Cannabis 216 (cannabis plant), as well as the synthetic equivalents of the 217 substances contained in the cannabis plant, or in the resinous 218 extractives of such plant, and/or synthetic