INDEX Volume 172, March-April 1970 Acetazolamide, influence on anion secretion into adrenergic, in rabbit aortic strips, interactions cerebrospinal fluid, 197 between potentiating agents of, 320 Acetylcholine(s) retention in rat heart, effect of bretylium on, 282 effect on adrenal catecholamine secretion, 69 syrnpathomimetic, mephentermine and, evalua- halogeno-, cholinergic activities of, 351 tion of vasodilation produced by, 297 nicotine and, comparison of effects on cycle Amino acids, y-aminobutyric acid and, actions on length and action potentials of guinea-pig mammalian autonomic ganglia, 384 atria, 255 ‘y-Aminobutyric acid, related amino acids and, Acetylsalicylic acid, combination with other actions on mammalian autonomic ganglia, 384 drugs, effects on inflammation induced by 7-Amino g-hydroxybutyric acid, effects on main- carrageenan, 423 malian autonoinic ganglia, 384 Acidosis, effects on chronotropic responses, nor- 3-Amino-1-propanesulfonic acid, effects on mam- epinephrine storage and release in isolated malian autonomic ganglia, 384 guinea-pig atria, 289 Amitriptyline, inhibition of metabolism of gua- Adipose tissue, of cattle, sheep, goats and swine, nethidine and related agents by hepatic mi- concentrations of thiopental in, 128 crosomes by, 108 Adrenalectomy, influence on nicotine-induced in- Amphetamine hibition of contractile activity in stomach effect on heart force in dogs, 297 and duodenum of dog, 377 retention in rat heart after bretylium, 282 Adrenal glands d-Amphetamine, potentiation of jumping activity effects of splanchnic nerve stimulation and induced by sodium 5-(1 ,3-dimethylbutyl)-5- cholinergic agents on secretion of catechola- ethyl barbiturate, 170 mines by, 69 Anesthesia release of catecholamines in response to nico- produced by thiopental in cattle, sheep, goats tine, 377 and swine, 128 Adrenergic amines, in rabbit aortic strips, inter- spinal, influence on nicotine-induced inhibition actions between potentiating agents of, 320 of contractile activity in stomach and duo- Adrenergic blockade denum of dog, 377 alpha and beta, and inotropic response to phen- Anesthetics ylephrine, 274 local, effects of pH gradients on action of pro- beta, of chronotropic effects of nicotine and caine and lidocaine in intact and desheathed norepinephrine in guinea-pig atria, 255 sciatic nerves, 1 effect of phentolamine on responses of normal, local, effects of pH gradients on uptake and dis- denervated and decentralized cat nictitating tribution of C’4-procaine and lidocaine in membrane to methoxamine and norepineph- intact and desheathed sciatic nerve trunks, 18 rine, 91 Anoxia, effect on release of norepinephrine from Adrenergic blocking drugs, beta, reduction of spleen, 342 jumping activity induced by sodium 5-(1,3- Antihistaminee, lack of influence on mephenter- dimethylbutyl)-5-ethyl barbiturate, 170 mine-induced vasodilation in dogs, 297 Adrenergic nerves, release of norepinephrine from Antimalarial drugs, chloroquine diphosphate and isolated rat iris by field stimulation, 332 RP-12278, neuromuscular blocking properties Adrenergic neurons, blockade by guanethidine of, 44 and related agents and antagonism by drugs, Aortic smooth muscle, comparison of retentions of 100 methoxamine and norepinephrine in, 91 AHR-0602, inhibition of contractile activity in Aortic strips stomach and duodenum of dog, 377 rabbit, antagonism of phentolamine against -Alanine, effects on mammalian autonomic gan. glia, 384 exogenously administered and endogenously Alpha adrenergic blockade, lack of effect on mo- released norepinephrine in, 310 tropic action of phenylephrine on rabbit atria, rabbit, interactions between potentiating agents 274 of adrenergic amines in, 320 Amine(s) Artery, pulmonary, main, isolated, rabbit, release 427 428 DmEx of H2-norepinephrine in relation to muscle tive inhibition by norepinephrine, guanethi- contraction in, 62 dine, debrisoquin, bretylium, tyramine, me- Askari, A. and Rae, S. N. : Drugs affecting sodium taraminob and desipramine, 100 transport in human erythrocyte ghosts, 211 Bevan, J. A., see Su, C., 62 Aspirin, combination with other drugs, effects on Bianchi, C. P. inflammation induced by carrageenan, 423 see Strobel, G. E., 1, 18 Atria see Suarez-Kurtz, G., 33 guinea-pig and cat, rate and contractile force, Bigger, J. T., Jr. and Mandel, W. J. : Effect of effect of gallamine on, 266 lidocaine on conduction in canine Purkinje guinea-pig, electrically driven, biphasic effect fibers and at the ventricular muscle-Purkinje of nicotine on action potential repolarization fiber junction, 239 in, 255 Bis [(chloro-7’ ‘-quinolyl-4”)amino-2’-propylj-1 , 4- guinea-pig, isolated, effects of acidosis on chro- piperazine (RP-12278), antimalarial agent, notropic responses, norepinephrine storage neuromuscular blocking properties of, 44 and release in, 289 Bladder, toad, effect of bendroflumethiazide on rabbit, blockade of inotropic action of phenyl- sodium transport and metabolism in, 203 ephrine by bretylium or cocaine in, 274 Blockade Atropine adrenergic, effect of phentolamine on responses and responses of denervated cat nictitating of normal, denervated and decentralized cat membrane , 77 nictitating membrane to methoxamine and blockade of effects of acetylcholine and nicotine norepinephrine, 91 in guinea-pig atria, 255 selective, of adrenergic neurons by guanethi- failure to inhibit positive inotropic response to dine and related agents, antagonism by drugs, gallamine, 266 100 lack of influence on mephentermine-induced Blood flow, effects of mephentermine and certain vasodilation in dogs, 297 other sympathomimetic amines on femoral, Autonomic ganglia, mammalian, actions of -y-ami- renal and superior mesenteric arteries in dogs, nobutyric acid and related amino acids on, 384 297 Azzaro, A. J., see Peach, M. J., 289 Boerth, R. C., Ryan, M. J. and Brody, M. J.: Pharmacologic blockade of reflex vasodilata- Barbiturate(s) tion : Effects on postulated neurohumoral in rhesus monkeys, development of tolerance to mechanisms, 52 and physical dependence on, 163 Brain sodium 5-(1 ,3-dimethylbutyl)-5-ethyl, jumping catecholamines synthesized from circulating activity induced by, role of sympathetic H’-tyrosine, daily rhythm in accumulation nervous system, 170 of, 416 Basal metabolism, effect of dioxoisoquinoline-4- dopamine levels in relation to pharmacologic carboxanilides on, 138 actions of L-dopa, 406 Bass, P., see Carlson, G. M., 367, 377 levels, of sodium 5-(1 ,3-dimethylbutyl) -5-ethyl Behavior, punished and unpunished, in pigeon, barbiturate, 170 effects of some benzodiazepines on, 397 of cattle, sheep, goats and swine, concentrations Bendroflumethiazide, effect on sodium transport of thiopental in, 128 and metabolism in toad bladder, 203 Bretylium Benzodiazepines blockade of release of H’-norepinephrine from effects on punished and unpunished behavior arterial strips, 62 in pigeon, 397 cocaine or, blockade of cardiac action of phen- lack of effect in inhibiting jumping activity in- ylephrine by, 274 dueed by sodium 5-(1 ,3-dimethylbutyl)-5- competitive inhibition of uptake of H1-beth- ethyl barbiturate, 170 anidine by heart slices, 100 Beta adrenergic blockade decreased potentiation of norepinephrine re- blockade of inotropic action of phenylephrine on spouses by cocaine after, 320 rabbit atria, 274 effect on amine retention in rat heart, 282 of chronotropic effects of nicotine and norepi- influence on responses of cat nictitating mem- nephrine in guinea-pig atria, 255 brane, 77 Beta adrenergic blocking drugs, reduction of jumping activity induced by sodium 5-(1,3- Broder, L. E., see Maren, T. H., 197 dimethylbutyl).5-ethyl barbiturate, 170 Brodie, B. B., see Koppanyi, T., 170 H.Bethanidine, uptake by heart slices, competi- Brody, M. J., see Boerth, R. C., 52 INDEX 429 Bromoacetylcholine, muscarinic and nicotinic -induced inhibition of contractile activity in activities of, 351 stomach and duodenum of dog, 367 Brown, B. R., Jr. and Crout, J. R. : The sym- potentiation of effects on rabbit aortic strips pathomimetic effect of gallamine on the heart, after inhibition of catechol-O-methyltraus 266 ferase with 4-tropolone acetamide, 320 BW 684-induced vasodilation in dogs, 297 release from spleen, effects of metabolic inhibi- tom on, 342 Calcium release resulting from administration of nico- influence on contracture produced by RP-12278, tine in dog, 377 44 retention in rat heart after bretylium, 282 inhibition of release of norepinephrine from iso- Catechol-Omethyltransfer, inhibition by lated rat iris by field stimulation in absence 4-tropolone acetamide in rabbit aortic strips, of, 332 320 Caidwell, R. W. and Goldberg, L. I. : An evalua- Cavanaugh, J. H., see Mitchell, J. R., 108 tion of the vasodilation produced by mephen- Cells, epithelial, effect of bendroflumethiazide on termine and certain other sympathomimetic sodium transport and metabolism in toad amines, 297 bladder, 203 Carbon dioxide, entry from blood into cerebro- Central nervous system, potentiation and inhibi- spinal fluid before and after inhibition of tion of some central actions of L-dopa by de- carbonic anhydrase, 197 carboxylase inhibitors, 406 Carbonic anhydrase, role in anion secretion into Cerebrospinal fluid cerebrospinal fluid, 197 in cattle, sheep, goats and swine, concentra. Cardiac glycosides tions of thiopental in, 128 effect on interaction of Ca with mitochondria, role of carbonic anhydrase in anion secretion 180 into, 197 six, effects on transmembrane potential and Chang, Y.-H., see Wiseman, E. H., 138 contractile characteristics