Estonian Statistics on Medicines 2017 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A ALIMENTARY TRACT AND METABOLISM 169,5987 A01 STOMATOLOGICAL PREPARATIONS 0,0723 A01A STOMATOLOGICAL PREPARATIONS 0,0723 A01AA Caries prophylactic agents A01AA01 Sodium fluoride (dental) 51 g A01AB Antiinfectives and antiseptics for local oral treatment 0,0723 A01AB09 Miconazole (O) 6958,4 g 0,2 g 0,0723 A01AB12 Hexetidine (O) 1802400 ml A01AB81 Neomycin+ Benzocaine (dental) 30900 pieces A01AB82 Demeclocycline+ Triamcinolone (dental) 460 g A01AD Other agents for local oral treatment A01AD80 Lidocaine+ Cetylpyridinium chloride (gingival) 210860 g A01AD81 Lidocaine+ Cetrimide (O) 34685 g A01AD82 Choline salicylate (O) 780560 pieces A01AD83 Lidocaine+ Chamomille extract (O) 371950 g A01AD90 Lidocaine+ Paraformaldehyde (dental) 528 g A02 DRUGS FOR ACID RELATED DISORDERS 48,6099 A02A ANTACIDS 1,0401 Combinations and complexes of aluminium, calcium and A02AD 1,0401 magnesium compounds A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 768200 pieces 10 pieces 0,1597 A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 3461134 ml 50 ml 0,1439 A02AD83 Calcium carbonate+ Magnesium carbonate (O) 3543408 pieces 10 pieces 0,7366 DRUGS FOR PEPTIC ULCER AND GASTRO- A02B 47,5697 OESOPHAGEAL REFLUX DISEASE (GORD) A02BA H2-receptor antagonists 2,1028 A02BA02 Ranitidine (O) 300308,25 g 0,3 g 2,0808 A02BA02 Ranitidine (P) 3175,75 g 0,3 g 0,022 A02BC Proton pump inhibitors 45,4595 A02BC01 Omeprazole (O) 257962,34 g 0,02 g 26,8113 A02BC02 Pantoprazole (O) 196205,1 g 0,04 g 10,1963 A02BC02 Pantoprazole (P) 461,2 g 0,04 g 0,024 A02BC03 Lansoprazole (O) 10,5 g 0,03 g 0,0007 A02BC05 Esomeprazole (O) 118787,76 g 0,03 g 8,2308 A02BC05 Esomeprazole (P) 2834,8 g 0,03 g 0,1964 A02BD Combinations for eradication of Helicobacter pylori <0,0001 A02BD08 Bismuth subcitrate+ Tetracycline+ Metronidazole (O) 120 pieces 12 pieces <0,0001 Other drugs for peptic ulcer and gastro-oesophageal reflux A02BX 0,0073 disease (GORD) A02BX02 Sucralfate (O) 13850 g 4 g 0,0072 A02BX05 Bismuth subcitrate (O) 33,6 g 0,48 g 0,0001 A02BX80 Vonoprazan (O) 3 g DRUGS FOR FUNCTIONAL GASTROINTESTINAL A03 7,9427 DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL A03A 7,0126 DISORDERS A03AA Synthetic anticholinergics, esters with tertiary amino group 0,9891 A03AA04 Mebeverine (O) 142746 g 0,3 g 0,9891 A03AB Synthetic anticholinergics, quaternary ammonium compounds <0,0001 A03AB02 Glycopyrronium (P) 0,006 g 3 mg <0,0001 A03AD Papaverine and derivatives 4,4561 A03AD01 Papaverine hydrochloride (P) 66,2 g 0,1 g 0,0014 A03AD02 Drotaverine (O) 210001,28 g 0,1 g 4,3653 A03AD02 Drotaverine (P) 4303 g 0,1 g 0,0894 A03AX Other drugs for functional gastrointestinal disorders 1,5674 A03AX13 Simeticone (O) 377005,5437 g 0,5 g 1,5674 A03B BELLADONNA AND DERIVATIVES, PLAIN 0,0905 1/42 Estonian Statistics on Medicines 2017 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A03BA Belladonna alkaloids, tertiary amines 0,0782 A03BA01 Atropine (O, P) 17,34 g 0,0015 g 0,024 A03BA01 Atropine (P) 39,08 g 0,0015 g 0,0542 Belladonna alkaloids, semisynthetic, quaternary ammonium A03BB 0,0123 compounds A03BB01 Hyoscine butylbromide (O) 51,8 g 0,06 g 0,0018 A03BB01 Hyoscine butylbromide (P) 297,9 g 0,06 g 0,0103 A03BB01 Hyoscine butylbromide (R) 6,24 g 0,06 g 0,0002 A03F PROPULSIVES 0,8396 A03FA Propulsives 0,8396 A03FA01 Metoclopramide (O) 9698 g 0,03 g 0,672 A03FA01 Metoclopramide (P) 1874,9 g 0,03 g 0,1299 A03FA03 Domperidone (O) 544,14 g 0,03 g 0,0377 A04 ANTIEMETICS AND ANTINAUSEANTS 0,1243 A04A ANTIEMETICS AND ANTINAUSEANTS 0,1243 A04AA Serotonin (5-HT3) antagonists 0,1107 A04AA01 Ondansetron (P) 34,76 g 0,016 g 0,0045 A04AA02 Granisetron (O) 59,76 g 0,002 g 0,0621 A04AA02 Granisetron (P) 63,61 g 0,003 g 0,0441 A04AD Other antiemetics 0,0136 A04AD01 Scopolamine (TD) 10 pieces 1 pieces <0,0001 A04AD12 Aprepitant (O) 332,025 g 0,095 g 0,0073 A04AD81 Fosaprepitant (P) 288,45 g 0,095 g 0,0063 A05 BILE AND LIVER THERAPY 2,2636 A05A BILE THERAPY 0,4938 A05AA Bile acid preparations 0,4938 A05AA02 Ursodeoxycholic acid (O) 178150 g 0,75 g 0,4938 A05B LIVER THERAPY, LIPOTROPICS 1,7698 A05BA Liver therapy 1,7698 A05BA03 Silymarin (O) 2644490 pieces A05BA80 Essential phospholipids (O) 2554230 pieces 3 pieces 1,7698 A05BA80 Essential phospholipids (P) 1945 pieces A06 DRUGS FOR CONSTIPATION 15,5975 A06A DRUGS FOR CONSTIPATION 15,5975 A06AB Contact laxatives 7,4335 A06AB02 Bisacodyl (O) 14969,2 g 0,01 g 3,1116 A06AB02 Bisacodyl (R) 999 g 0,01 g 0,2077 A06AB06 Senna glycosides (O) 8440 pieces 1 pieces 0,0175 A06AB08 Sodium picosulfate (O) 9852,8073 g 0,005 g 4,0962 A06AB80 Sodium picosulfate+ Magnesium oxide+ Citric acid (O) 460 pieces 2 pieces 0,0005 A06AC Bulk-forming laxatives <0,0001 A06AC01 Hemicellulose of Ispaghula (O) 0,585 g 7 g <0,0001 A06AD Osmotically acting laxatives 7,3069 A06AD11 Lactulose (O) 22314644,9 g 6,7 g 6,9232 A06AD15 Macrogol (O) 1846000 g 10 g 0,3837 Macrogol+ Sodium citrate+ Citric acid+ Sodium chloride+ A06AD80 14400 ml Potassium chloride (O) Sodium sulphate, anhydrous+ Potassium chloride+ Sodium A06AD81 58596 pieces chloride+ Macrogol+ Sodium hydrogen carbonate (O) Macrogol+ Sodium sulphate, anhydrous+ Sodium chloride+ A06AD83 280 pieces Potassium chloride+ Ascorbic acid+ Sodium ascorbate (O) Sodium sulphate, anhydrous+ magnesium sulfate A06AD85 796224 ml heptahydrate+ Potassium sulphate (O) A06AG Enemas 0,8499 A06AG11 Laurilsulfate, incl. combinations+ Sorbitol+ Sodium citrate (R) 408872 pieces 1 pieces 0,8499 A06AH Peripheral opioid receptor antagonists 0,0071 2/42 Estonian Statistics on Medicines 2017 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A06AH03 Naloxegol (O) 85,5 g 25 mg 0,0071 ANTIDIARRHEALS, INTESTINAL A07 4,0713 ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS A07A INTESTINAL ANTIINFECTIVES 0,0003 A07AA Antibiotics 0,0003 A07AA02 Nystatin (O) 20000000 U 1500000 U <0,0001 A07AA06 Paromomycin (O) 42 g A07AA11 Rifaximin (O) 55,2 g 0,6 g 0,0002 A07AA12 Fidaxomicin (O) 8 g 0,4 g <0,0001 A07B INTESTINAL ADSORBENTS 0,4412 A07BC Other intestinal adsorbents 0,4412 A07BC05 Diosmectidum (O) 1910070 g 9 g 0,4412 A07C ELECTROLYTES WITH CARBOHYDRATES A07CA Oral rehydration salt formulations Sodium chloride+ Potassium chloride+ Sodium citrate+ A07CA80 68200 pieces Glucose (O) A07D ANTIPROPULSIVES 0,9968 A07DA Antipropulsives 0,9968 A07DA03 Loperamide (O) 4795,472 g 0,01 g 0,9968 A07DA06 Eluxadoline (O) 16,8 g A07E INTESTINAL ANTIINFLAMMATORY AGENTS 2,0161 A07EA Corticosteroids acting locally 0,0023 A07EA06 Budesonide (O) 9,99 g 0,009 g 0,0023 A07EA06 Budesonide (R) 0,9352 g A07EC Aminosalicylic acid and similar agents 2,0137 A07EC01 Sulfasalazine (O) 796650 g 2 g 0,828 A07EC02 Mesalazine (O) 788185 g 1,5 g 1,0923 A07EC02 Mesalazine (R) 67458 g 1,5 g 0,0935 A07F ANTIDIARRHEAL MICROORGANISMS 0,617 A07FA Antidiarrheal microorganisms 0,617 A07FA02 Saccharomyces boulardii (O) 296797,5 g 1 g 0,617 A07X OTHER ANTIDIARRHEALS A07XA Other antidiarrheals A07XA04 Racecadotril (O) 3311 g A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0522 A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS 0,0522 A08AA Centrally acting antiobesity products 0,0363 A08AA62 Bupropione+ Naltrexone (O) 69776 pieces 4 pieces 0,0363 A08AB Peripherally acting antiobesity products 0,016 A08AB01 Orlistat (O) 2766,96 g 0,36 g 0,016 A09 DIGESTIVES, INCL. ENZYMES 1,4828 A09A DIGESTIVES, INCL. ENZYMES 1,4828 A09AA Enzyme preparations 1,4827 A09AA02 Lipase+ Amylase+ Protease (O) 2853211 pieces 4 pieces 1,4827 A09AC Enzyme and acid preparations, combinations 0,0001 A09AC80 Pepsin+ Betaine (O) 150 pieces 3 pieces 0,0001 A10 DRUGS USED IN DIABETES 62,3756 A10A INSULINS AND ANALOGUES 16,3017 A10AB Insulins and analogues for injection, fast-acting 6,1563 A10AB01 Insulin (human) (P) 874500 U 40 U 0,0454 A10AB04 Insulin lispro (P) 25911000 U 40 U 1,3465 A10AB05 Insulin aspart (P) 77940000 U 40 U 4,0503 A10AB06 Insulin glulisine (P) 13738500 U 40 U 0,714 A10AC Insulins and analogues for injection, intermediate-acting 0,1188 A10AC01 Insulin (human) (P) 2286000 U 40 U 0,1188 Insulins and analogues for injection, intermediate- or long- A10AD 1,2917 acting combined with fast-acting 3/42 Estonian Statistics on Medicines 2017 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A10AD04 Insulin lispro (P) 8655000 U 40 U 0,4498 A10AD05 Insulin aspart (P) 16201500 U 40 U 0,842 A10AE Insulins and analogues for injection, long-acting 8,7349 A10AE04 Insulin glargine (P) 102192750 U 40 U 5,3107 A10AE05 Insulin detemir (P) 65892000 U 40 U 3,4242 A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS 46,0739 A10BA Biguanides 20,0821 A10BA02 Metformin (O) 19321782 g 2 g 20,0821 A10BB Sulfonylureas 14,4784 A10BB07 Glipizide (O) 1154,55 g 0,01 g 0,24 A10BB09 Gliclazide (O) 232998,6 g 0,06 g 8,0722 A10BB12 Glimepiride (O) 5932,68 g 0,002 g 6,1661 A10BD Combinations of oral blood glucose lowering drugs 5,0782 A10BD07 Metformin+ Sitagliptin (O) 2025856 pieces 2 pieces 2,1056 A10BD08 Metformin+ Vildagliptin (O) 949140 pieces 2 pieces 0,9865 A10BD10 Metformin+ Saxagliptin (O) 321240 pieces 2 pieces 0,3339 A10BD11 Metformin+ Linagliptin (O) 769740 pieces 2 pieces 0,8 A10BD15 Metformin+ Dapagliflozin (O) 255024 pieces 2 pieces 0,2651 A10BD19 Linagliptin+ Empagliflozin (O) 17910 pieces 1 pieces 0,0372 A10BD20 Metformin+ Empagliflozin (O) 495780 pieces 2 pieces 0,5153 A10BD21 Saxagliptin+ Dapagliflozin (O)