Genetics of Sesame Street Name __________________ Period __________________ Introduction Much is known about the genetics of Sesamus muppetis. Karyotyping reveals that Sesame Street characters have six chromosomes: two homologous pairs and one pair of sex chromosomes. Chromosome pair #1 is the largest and has a centrally placed centromere. Chromosome pair #2 is much shorter with the centromere at one end. Sex is determined by X and Y chromosomes, just as it is in the related species, Homo Sapiens. Through the process of gene mapping, geneticists have found the specific locations of the genes for eye shape, nose color, lip color, body color, and hair type. By observing the offspring of many crosses, geneticists also have determined the types of inheritance that several of these genes exhibit. Objective In this lab you will determine the genotypes of six Sesame Street characters, and choose two individuals to cross and produce a male & female child. The ability to do monohybrid crosses and predict probability will be essential. This project will be worked on primarily in class. Requirements 1. Completion of “Phenotype & Genotype Table” 5 pts. a. For each Sesame Street character, describe each of the traits on the table on Page 3. b. Use the Genetics of Sesame Street Characters Table (Page 3) to determine the possible genotypes for each of the Sesame Street characters based on each character’s phenotypes. We will use this information to fill in both genotype and phenotype on our table. 2. Completion of “Muppet Mate’s Characteristics” 5 pts. 3. Completion of “Punnett Squares & Probabilities” 10 pts. Use the six Punnett Squares to show the possible outcomes for male and female characters in your project. The probabilities, expressed as ratios or percents, must be listed for each possible trait. 4. Completion of “Muppet Babies’ Characteristics and Sketch” 10 pts. 5. Family Portrait 20 pts. Create a family portrait of your male, female, and both offspring. The portrait should match the genetic description of your characters. Total = 50 points Genetics of Sesame Street Characters Characteristic Phenotype Genotype Type of Inheritance Eye Shape Exo (pops EE, Ee Dominant out) ee Recessive Endo (flat) Nose Color Pink PP or Pp Complete Dominance Orange pp Lip Style Matching Fur MM or Mm Complete Dominance Color Grover-Style mm (red bottom lip) Body Color Red RR Multiple Alleles: Magenta RB R, B, & O. Pink RO Incomplete Blue BB Dominance Teal BO Orange OO Hair Type Hairy XH Dominant Bald Xh Recessive (sex- linked) Phenotypes & Genotypes Table Eye Nose Lip Body Hair Shape Color Color Color Type Grover Elmo Telly Rosita Abby Zoe Muppet Mates’ Characteristics Using a female and a male Muppet from the list please record the characteristics for each category. You will “breed” these mates together to create two “Muppet Babies” of your own (a male and a female). Characteri Phenotype Male’s Female stics (Circle) Genotypes Genotypes Name Grover Elmo Name__________ Name___________ Telly Abby Cadabby Zoe Rosita Eye Shape Exo (pops out) Endo (flat) Nose Color Pink Orange Lip Style Matching Fur Grover- style Body Color Red Magenta Pink Blue Teal Orange Hair Type Hairy (X-linked) Bald Choose a heterozygous genotype whenever possible! Punnett Squares for “Muppet Babies” Please fill out the following Punnett Squares in order to determine the possible traits of your Muppet Babies. Male gametes on the side, female gametes on the top. Then, using the space below each Punnett Square, tell the probability for each phenotype (dominant and recessive). Eye Shape Body Color Nose Color ___________ ____________ __________ Lip Style Hair Type Gender _____________ _____________ ___________ “Muppet Babies” Characteristics Using your Meiosis Map and your combination of gametes, list the characteristics of each of your babies. Remember, the characteristics of each baby MUST have been possible when using the Punnett Squares. Boy Girl Name Eye Shape Body Color Nose Color Lip Style Hair Type Please make a sketch of each Muppet Baby below. This will serve as a rough draft for your family portrait. Boy Girl Family Portrait (Mom, Dad, and babies; in color) .