Migal- Galilee Research Institute Our goal is to lead outstanding and impactful research while collaborating with industry, academy and research institutes. Was established in 1979 (100% The Biggest researCh institute in the ownership of the Galilee Galilee and the Golan heights (Mega 01 Development). Funded by the Ministry 02 R&D) of SCienCe 41 ResearCh groups, 296 Employees, 7500 sq ft of lab spaCe in Kiryat 03 83 PhD. 04 Shmona and Tel-Hai Industrial park. Affiliated with Tel-Hai College In the process of building a new laboratory building in Tel Hai campus. EconomiC Development Region & ECosystem AcademiC ExCellence Tel-Hai College Introductory Presentation Innovation's True North Examples of research fields among leading Research professors and researchers Faculty of Sciences and Technology Hydrochemistry Environmental Chemistry Prof. Michael Litaor Prof. Giora Rytwo Official affiliation with MIGAL - Applied scientific research, Galilee Research Institute specializing in the fields of Natural compounds Immunology biotechnology, environmental and agriculture sciences Prof. Soliman Khatib Prof. Gidi Gross Molecular Genetics in Human Health Agriculture and Nutrition Sciences Prof. Martin Goldway Prof. Snait Tamir Plant Metabolism Prof. Rachel Amir Academics Faculty of Sciences & Technology B.Sc. M.Sc. Biotechnology Biotechnology- Thesis track Nutrition Science Nutritional- Thesis track Food Science Water Science- Thesis track Animal Science Computer Science Graduate School Computer Science Environmental Science Pre-Med Studies Number of students Number of Employees Statistics 5,000 1,000 Our students Where do our students come from? Where do our students continue on to? Graduates Type of Studies Number of Students Percentage M.Sc. 371 16.3 M.A. 823 36.2 Doctorate 126 5.5 Post Doctorate 1 0.04 Explore Community Creativity International EntrepreneurshipSuccess Leaders Sharing Academia INNOVATION ResearchTel-HaiAcademiCs 2030Excellence Pioneering Opportunities Dream Collaborations Expending Implement Curiosity Quality Knowledge Scientific Structure Supreme Scientific 1 Council 2 Internal Scientific Council Scientific Director 3 4 Department Managers Head of the 5 research group Due to our scope of operation, number of researches, and the composition of the Supreme Scientific Council, per the criteria set forth by the Ministry of Science we are not required to have an academic sponsorship from another intitute . Scientific Council Name Academic Institution Field Prof. Aaron Ciechanover Technion Chemistry Prof. Yitzhak Apeloig Technion Chemistry Prof. Rafael (Rafi) Beyar Technion/Rambam H Medicine Prof. Gadi Schuster Technion Biology Prof. Moshe Shoham Technion Medical Robotics Prof. Ohad Birk Ben Gurion University Genetics Prof. Michal Shapira Ben Gurion University Biology Prof. Hanoch Gutfreund Hebrew University Physics Prof. Yitzhak Hadar Hebrew University Microbiology Prof. Hermona Soreq Hebrew University Biological Chemistry Prof. Oded Shoseyov Hebrew University Biotechnology Prof. Tamar Peretz Hebrew University/Hadassah H Oncology Prof. Tamar Dayan Tel - Aviv University Oncology Scientific Council Name Academic Institution Field Prof. Yoseph Mekori Immunology Tel Hai College Prof. Dan Levanon Biotechnology/Scientific Director MIGAL Prof.Giora Rytwo Chemistry MIGAL/Tel Hai College Prof. Michael Litaor Chemistry MIGAL/Tel Hai College Prof. Gideon Gross Immunology MIGAL/Tel Hai College Prof. Snait Tamir Nutrition MIGAL/Tel Hai College Prof. Rachel Amir Biology MIGAL/Tel Hai College Prof. Gad Degani Endocrinology MIGAL/Tel Hai College Prof. Jacob Pitcovski Immunology MIGAL/Tel Hai College Migal Structure- Research Departments and Services Units Plant SCienCe BioteChnology Nutrition and Soil Water and Natural ProduCts Environment Post Harvest North R&D innovation Center Main research disciplines Title of the Slide Subject Environmental Biotechnology Biochemistry Food Chemistry Computational Smart Agriculture Sciences and Research Bioinformatics Food & Biobase Plant Research Post Harvest Livestock Cannabis research Nutrition Northern R&D – an independent unit within MIGAL “MOP TZAFON” is the agricultural R&D unit in the north. It outlines, coordinates and executes the applicatory agricultural research and development in the northern part of Israel. v Operates in all the Gallil & Golan districts and also in the Jorden valley. v Production of over 6 billion NIS fresh produce year. v Sub topo climatic regions from -200m and up to 1200m above see level. v Vast types of soils, water quality and availability. v Research is performed in 10 different experiment sites. Migal Regional Value Creation platform Excellence Center Community R&D Local Galil Municipalities Develop ment Education קחמ ר ח Education Food Tech חותפו חותפו Industry Industry Startups Accelerator University Research Institute — Scientific Excellence 160 160 160 80 220 80 220 80 220 0 280 0 280 0 280 Scientific Excellence, Business model, Centers of Excellence Regional Development Bioinformatics v During the upcoming decade v 18-22startup companies v Center of excellence for we plan to hire v Collaborations with the vaccine development v 16-20young chief industry and agriculture v The Center for Plant researchers leaders Biodiversity Research, and v 30-40research staff v Computational and potential uses as crops and members Bioinformatics educational medical herbs v 4-6senior scientists for and training programs v Sustainability, Agriculture, limited terms v Implementing the Climate, and the v 20-25doctoral student and computational aspect in all Environment postdoctoral researchers our research fields GALIL CENTER OF EXCELLENCE FOR VACCINE DEVELOPMENT NEXT-GENERATION DIFFERENTIATION FOCUS PROJECTS PARTNERS VACCINES ü Accelerating and de-risking ü The multi-disciplinary ü Develop platform technologies the development of new capabilities, facilities and as building blocks including ü Ministry of Science and vaccines varied expertise of its Structural biology and Technology ü Developing specific oral founding partners. bioinformatics tools. ü MIGAL Galilee Research vaccines as a “Proof of ü The physical proximity of its ü Develop next-generation Institute Concept” main laboratory and clinical diagnostic tools including an ü Rambam Medical Cente ü Improving the ability to facilities “in-silico” system ü Technion – Israel predict and develop highly ü Israel’s “start-up nation” ü Developing a model to enable Institute of Technology active vaccines cultural mentality accurate prediction, to ü Stanford University development of wide-range ü The Israel Veterinary vaccines against fast-changing institute and newly emerging viruses (e.g. influenza, coronavirus etc.). The best framework would be a Center of Excellence to function as an umbrella organization for prioritizing, funding and managing multi-disciplinary projects carried out through collaborations between innovative academic, applied research and medical institutions. Senior Research Scientist positions Organic Chemistry Soil Chemistry Focusing on Natural Compounds Chemistry: isolation Prioritized subjects: nutrient modeling, enviro-friendly and activity of health-promoting and food-related fertilizer/pesticide application, precision agriculture natural compounds, rational synthesis of bioactive methods (e.g., soil proximal survey techniques, molecules, metabolomics. multispectral analysis). Plant Sciences Immunology Focusing on natural compounds for Health-Value Foods With focus on either immunotherapy or vaccinology: (background and experience in botany, biochemistry emerging methods for wide-range vaccines, design of molecular biology, and genetics). effective adjuvants to stimulate innate immunity and active cellular immunotherapy. Plant Genomics Computational/Synthetic Biology Covering areas such as evolution, development, Advanced computational methods to study operating physiology, ecology, and plant interactions with other principles of complex biological systems (from intra/ organisms (background in comparative and functional inter-cellular down to metabolic pathways), design and genomics and expertise in bioinformatics). engineering of small biomolecules. Sphingolipids and bioactive compounds in inflammation and cancer Lab Dr. Dorit Avni Research Group Leader Sphingolipids and bioactive compounds in inflammation and cancer. [email protected] https://www.migal.org.il/en/node/6848 AcademiC Positions 2018-present, Head of sphingolipids and immune modules laboratory, MIGAL 2012-2016, Postdoctoral Fellow at Massey Cancer Center, VCU-MCV, USA. Topics of research 1. Role of sphingolipids in health and disease 2. Natural bioactive compounds as immune regulators # Holistic approach - The use of nutritional and natural compounds as prevention or treatment for human disease and the regulation of the immune system # Identifying unmet disease and providing new platforms and solutions:COVID19, IBD, NAFLD, gastric ulcer, TNBC, liver cancer Our research comprises of both basic and translational programs Our laboratory specializes in in-vitro, ex-vivo and pre-clinical models and we take a transdisciplinary approach in our research using immunologic, genomic, and metabolomic approaches to study our open questions. Vascular signaling Lab Dr. Andrea Szuchman-Sapir Research Group Leader Vascular signaling Lab. [email protected] https://www.migal.org.il/en/Andrea-Szuchman-Sapir Academic Positions Ph.D. 2006, Technion Faculty of Medicine, Haifa, Israel. 2017- Head of the Laboratory of vascular signaling research, Migal-Galilee