62ND ASMS CONFERENCE ON MASS SPECTROMETRY AND ALLIED TOPICS June 15 - 19, 2014 • Baltimore, maryland Welcome to the 62nd ASMS Conference on Mass Spectrometry and Allied Topics. Conference program activities and exhibit booths are in the Baltimore Convention Center. Corporate Member hospitality suites are located in the Hilton Hotel. SPONSORS ASMS gratefully acknowledges the support TABLE OF CONTENTS of these companies. GENERAL INFORMATION ....................................... 2 HOTELS AND TRANSPORTATION ........................... 5 ASMS BOARD OF DIRECTORS ............................ 6 INTEREST GROUPS AND COMMITTEES .................. 7 AWARDS.............................................................. 8 Mobile App and WiFi CONVENTION CENTER FLOOR PLANS ................ 10 POSTER / EXHIBIT HALL FLOOR PLAN ...............11 CORPORATE HOSPITALITY SUITES ..................... 12 Closing Event ASMS CORPORATE MEMBERS ......................... 13 PROGRAM ACKNOWLEDGEMENTS ....................... 17 CONFERENCE SPONSORS PROGRAM OVERVIEW ........................................ 18 WORKSHOPS ..................................................... 23 Titles in the following sections are provided by authors. The complete abstracts are available online: www.asms.org The PDF document of proceedings submissions for orals and posters may be viewed online one day after presentation at the conference. SUNDAY ............................................................ 28 MONDAY ORAL SESSIONS ................................. 28 TUESDAY ORAL SESSIONS ................................. 34 ONTRIBUTORS C WEDNESDAY ORAL SESSIONS ............................ 41 Fluid Management Systems THURSDAY ORAL SESSIONS .............................. 47 IDEX Health & Science MONDAY POSTERS ............................................ 54 New Objective, Inc TUESDAY POSTERS Prosolia, Inc ............................................ 88 Silicon Kinetics WEDNESDAY POSTERS ..................................... 122 Tandem Labs THURSDAY POSTERS ....................................... 156 Thermo Scientific INDEX OF AUTHORS ........................................ 190 Zef Scientific 62ND ASMS CONFERENCE ON MASS SPECTROMETRY PAGE 1 GENERAL INFORMATION REGISTRATION is open 10:00 am - 8:00 pm on Sunday and PLENARY SESSIONS 7:30 am - 5:00 pm on Monday through Thursday. MONDAY, 4:45 - 5:30 PM SundAy tutoriAl SeSSion, 5:00 - 6:30 pM AWARD LECTURE Exhibit Hall AB, level 1 Exhibit Hall AB, level 1 Award for a Distinguished 5:00 - 5:45 pm Contribution in Mass Spectrometry Mass Spectrometry in the Pharmaceutical Industry: Everything Richard M. Caprioli You Ever Wanted to Know but Were Vanderbilt University Afraid to Ask Lucinda Cohen Merck Research Laboratories TUESDAY, 4:45 - 5:30 PM AWARD LECTURE 5:45 - 6:30 pm Exhibit Hall AB, level 1 Imaging Mass Spectrometry Ron M.A. Heeren Biemann Medal FOM-AMOLF Lingjun Li University of Wisconsin-Madison 6:45 - 7:45 PM, SUNDAY SundAy ConferenCe opening, 6:45 - 7:45 pM 6:45 - 7:45 PM, SUNDAY Exhibit Hall AB, level 1 level THURSDAY, 4:45 - 5:30 PM Welcome, Jenny Brodbelt, PLENARY LECTURE University of Texas, Austin Exhibit Hall AB, level 1 CONFERENCE OPENING ASMS Vice President for Programs Exhibit Hall A, Exhibit level How the Genome Folds Erez Lieberman Aiden Baylor College of Medicine and Rice University The James Webb Space Telescope: From First Light to the Search for Earth 2.0 Jason Kalirai DON’T MISS Telescope Science Institute • ASMS Meeting, WedneSdAy, 4:45 - 5:30 pM Ballroom I, level 4 Enjoy a beverage while you applaud awards, hear about new initiatives, and more! • CloSing event, thurSdAy, 6:30 - 9:00 pM SundAy WelCoMe reCeption, 7:45 - 9:00 pM National Aquarium Exhibit Hall C-G. Conference name badge is required. Let’s celebrate! Enjoy all the aquarium has to offer including an Imax film and a dolphin event. Complete your tour with Exhibit Hall BC, Exhibit level music provided by a talented group of your colleagues. Ticket is required, $30. PAGE 2 62ND ASMS CONFERENCE ON MASS SPECTROMETRY GENERAL INFORMATION ORAL SESSIONS are 8:30 - 10:30 am and 2:30 - 4:30 pm on WORKSHOPS are 5:45 - 7:00 pm on Monday, Tuesday, and Monday through Thursday. Wednesday. Light refreshments are provided in the pre-function Session A (MOA, TOA, WOA, ThOA) .....Exhibit Hall AB, level 1 area on level 3. Session B (MOB, TOB, WOB, ThOB) .... Room 307-308, level 3 Session C (MOC, TOC, WOC, ThOC) ... Room 309-310, level 3 dinner BreAk, 7:00 - 8:00 pM is time for a breath of fresh air Session D (MOD, TOD, WOD, ThOD) ... Room 314-317, level 3 before the opening of hospitality suites at 8:00 pm. Session E (MOE, TOE, WOE, ThOE) ............ Ballroom I, level 4 Session F (MOF, TOF, WOF, ThOF) ............. Ballroom II, level 4 SPECIAL PROGRAM FOR UNDERGRADUATE STUDENTS Session G (MOG, TOG, WOG, ThOG) ........ Ballroom III, level 4 • Poster competition, 7:45 - 9:00 pm, Sunday, Poster/Exhibit Hall Session H (MOH, TOH, WOH, ThOH) ......... Ballroom IV, level 4 • Breakfast Tutorial “Make the Most of ASMS: What to See, Hear and Do! 7:00 - 8:15 am, Monday, Room 319 ORAL PRESENTATIONS are projected from ASMS computers (beverages and pastries provided) running Microsoft Office 2010. Speakers are required to use the • Meet the Experts at lunch tables reserved for undergraduate ASMS computers for their presentations. students, 12:00 - 1:00 pm, Monday, Poster/Exhibit Hall SPEAKERS must load presentations at least one day prior to their FREE WIFI ACCESS is provided in the Poster/Exhibit Hall. talks. The speaker room is 330 (behind conference registration Computers are provided at stations throughout the convention center. area) and is open with a technician according to this schedule: Sunday: 10:00 am - 8:00 pm CONFERENCE PROCEEDINGS will be published online. Visit www. Monday through Wednesday: 7:30 am - 5:00 pm asms.org after July 21 to view or download the Proceedings. Submission to the Proceedings does not constitute publication POSTERS AND EXHIBIT BOOTHS are in Exhibit Hall C-G. The Hall and does not jeopardize the rights of authors to publish contents is open: of their submissions. Speaker web casting slides will be Sunday Reception ....................7:45 pm - 9:00 pm printed to PDF and used for speakers who fail to submit. Monday - Wednesday ..............7:30 am - 8:00 pm Thursday .................................7:30 am – 3:00 pm WEB CASTING includes tutorial lectures, plenary lectures, and oral sessions. Web casting will be available to conference POSTER SET-UP is 7:30 am on the day scheduled and removal attendees for three months after the conference. ASMS does is 7:30 – 8:00 pm on the same day. Posters should not be not retain rights to material included in web castings. To access removed early. Thursday posters must be removed by 3:30 pm. the presentations, go to www.asms.org, select “web casting” on Refer to the poster numbers in this final program for board the annual conference page, and enter your last name and the assignments. Presenters should supply pushpins or Velcro to User ID printed on your conference name badge. mount their posters. CORPORATE HOSPITALITY SUITES may be open 8:00 - 11 pm, POSTER SESSIONS are 10:30 am – 2:30 pm, Monday through Monday through Wednesday. Suites are located in the Hilton Thursday. Special “themed refreshments” will be offered Hotel. 1:30 - 2:30 pm daily. CAREER CENTER is located in the Poster/Exhibit Hall. The Career POSTER AUTHORS must be present at posters on scheduled Center is open to all conference attendees. Applicants and days at these times. employers must enter resumes and employment opportunities 10:30 am - 1:00 pm ...........Odd-numbered posters online. There are computers in the center for searching the 12:00 - 2:30 pm ............... Even-numbered posters database of candidates and positions. Interview booths must be Presenters who must leave a poster unattended should post a reserved one day in advance. return time. Presenters should wear “Poster Presenter” badges Sunday ............................................7:45 - 9:00 pm which are available at the poster supply counter. Monday – Wednesday...............7:30 am - 5:00 pm Thursday ...................................7:30 am - 2:30 pm Posters should not be removed before 7:30 pm on Monday, Tuesday and Wednesday. Thursday posters should be removed GUEST REGISTRATION ($10) includes designated name badge at 2:30 pm. and entrance to the Sunday evening reception. The badge does not gain entrance to oral sessions or the Poster/Exhibit Hall. LUNCH CONCESSIONS in the Poster/Exhibit Hall offer a variety of options to dine and network while taking a break from posters. CONCIERGE DESK in the conference registration area offers Concessions are open 11:00 am - 2:00 pm, Monday through information on transportation, attractions and restaurants. Thursday. EXHIBITORS must staff exhibit booths as follows: Sunday Reception ....................7:45 pm - 9:00 pm Monday - Thursday ................10:30 am - 2:30 pm 62ND ASMS CONFERENCE ON MASS SPECTROMETRY PAGE 3 GENERALGENERAL INFORMATION INFORMATION CORPORATE BREAKFAST SEMINARS are hosted by some MEDIA EVENTS Corporate Members. Breakfast seminars are located in the Corporate media sessions are scheduled on Monday and convention center and start at 6:45 am on scheduled day. Tuesday for members of the press and financial institutions. Please reserve a seat at company exhibit booths. MONDAY Company Monday Hilton Hotel Location Convention Center Company Bruker Daltonics 8:00-9:00 am Key Ballroom 6 Location AB SCIEX Room