Comparing DNA Test Results Why take a DNA test? Family Legend... My Father’s Side: My Mother’s Side: ● Paternal Grandfather - ● Maternal Grandfather - ○ Born in Puerto Rico ○ Born in Virginia ○ Last name originates from Spain ○ Last name originates from England ○ His father was from Spain (very white, blue ○ Old Virginia family, claims of 1607 eyes) migration ● Paternal Grandmother - ● Maternal Grandmother - ○ Born in Puerto Rico ○ Born in Virginia ○ Last name originates from Spain ○ Last name originates from Germany ○ No knowledge of her family ○ Family been in Virginia for a long time Father’s Genetic My Potential Mother’s Genetic Makeup Genetic Makeup Makeup American 13.1 6.5 0 Ashkenazi Jewish 0.9 0.4 0 Central / South Asian 0.3 0.2 0 East Asian 0.7 0.4 0 European 59.0 79.0 99.0 Sub-Saharan African 15.7 7.8 0 West Asian / North African 3.4 2.1 0.8 Unassigned 6.9 3.6 0.2 Family Tree DNA ● Cost: $91.95 ● Sample Sent: September 22 ● Sample Received: September 29 ● Results Ready: October 19 Family Finder, Chromosome Browser myOrigins Ancient Origins My Potential My Actual Family Genetic Makeup Tree DNA Results American 6.6 5.0 (-1.6) Ashkenazi Jewish 0.5 0 (-0.5) Central / South Asian 0.2 0 (-0.2) East Asian 0.4 0 (-0.4) European 79.0 82 (+3.0) Sub-Saharan African 7.9 9 (+1.1) West Asian / North African 2.1 2 (-0.1) Unassigned 3.6 2 (-1.6) AncestryDNA ● Cost: $99 (each additional test is $89) ● Sample Sent: December 4 ● Sample Received: December 12 ● Results Ready: December 26 DNA Matches Thrulines Family Tree My Potential My Actual Genetic Makeup Ancestry Results American 6.6 7.0 (+1.6) Ashkenazi Jewish 0.5 0 (-0.5) Central / South Asian 0.2 0 (-0.2) East Asian 0.4 0 (-0.4) European 79.0 84.0 (+5.0) Sub-Saharan African 7.9 9.0 (+1.1) West Asian / North African 2.1 0 (-2.1) Unassigned 3.6 0 (-3.6) 23andMe ● Cost: $199 (Ancestry $99 + Health $125) ● Sample Sent: May 22 ● Sample Received: May 24 ● Results Ready: June 2 Skin Color Detached Earlobes DNA Relatives Ancestors My Potential My Actual Genetic Makeup 23andMe Results American 6.6 6.4 (-0.2) Ashkenazi Jewish 0.5 0.1 (-0.4) Central / South Asian 0.2 0.2 East Asian 0.4 0.1 (-0.3) European 79.0 79.1 (+0.1) Sub-Saharan African 7.9 9.9 (+2.0) West Asian / North African 2.1 1.9 (-0.2) Unassigned 3.6 2.3 (-1.3) Father’s Genetic My Potential My Actual Mother’s Genetic Makeup Genetic Makeup 23andMe Results Makeup Ashkenazi Jewish 0.9 0.5 0.1 (-0.4) 0 British & Irish 0.8 15.8 9.1 (-6.7) 28.8 Eastern European 0 0.3 0 (-0.3) 0.5 French & German 1.1 25.0 31.6 (+6.6) 48.9 Italian 0.7 0.2 0 (-0.2) 0.1 Scandinavian 0 1.5 2.2 (+0.7) 3.0 Spanish & Portuguese 43.3 21.7 22.7 (+1.0) 0 Misc. Euro. 13.1 15.4 13.6 (-1.8) 17.6 American 5.0 7.0 6.4 Ashkenazi Jewish 0 0 0.1 Central / South Asian 0 0 0.2 East Asian 0 0 0.1 European 82 84.0 79.1 Sub-Saharan African 9 9.0 9.9 West Asian / North African 2 0 1.9 Unassigned 2 0 2.3 GEDMatch Comparison Compiled Results Privacy 23 & Me Ancestry FamilyTreeDNA ● Barcode ● Barcode ● User ID number ● No one has access to both ● No one has access to both ● Need to give consent for third email + genetic info email + genetic info parties to access info ● Partnerships - can opt out ● Cannot turn off your ● Ambiguous about ownership “Consent to Research” ● Partnerships - need to get your consent first “We believe that you own your data” Retention 23 & Me Ancestry FamilyTreeDNA ● Store your sample ● Store your sample ● Store your sample so you can ● They’ll ask you your ● You can delete your test order more tests later preference results ● Once you give it to them, it’s ● Store for 1-10 years ● Need to call Member Services theirs ● Need to submit request to to have sample destroyed ● It can’t be destroyed or have sample destroyed returned to you Other Services ● Helix/Genographic Project (National Geographic) ~ Geno2.0 ● MyHeritage ● Living DNA (British results) ● HomeDNA ● Ancestry by DNA ● Human Genome Project (NIH) ● GEDmatch So what do you do with this information? Overall Impressions References ● https://www.technologyreview.com/s/610233/2017-was-the-year-consumer-dna-testing-blew-up/ ● https://www.yourdnaguide.com ● http://thednageek.com/who-owns-your-genetic-information/ ● https://www.washingtonpost.com/technology/2018/07/31/ancestry-andme-others-say-they-will-follow- these-rules-when-giving-dna-data-businesses-or-police/?noredirect=on&utm_term=.e138df259408 ● https://fpf.org/wp-content/uploads/2018/07/Privacy-Best-Practices-for-Consumer-Genetic-Testing- Services-FINAL.pdf ● https://www.prnewswire.com/news-releases/family-tree-dna-will-never-sell-your-genetic-data- 300562348.html ● https://www.businessinsider.com/best-dna-test-23andme-ancestry-national-geographic-2017-4 .