Supplementary Table S5. Protein expression changes in the functionally annotated categories within cluster from Figure 13A. Human ATPase activity regulation equivalent Accession Zq FDR No. Ac. No. No. Protein 120 1 4 7 120 1 4 7 peptides - I3LJX7 PIG Uncharacterized protein TOR1AIP2 0.01 0.00 0.78 1.03 1 - Q06AA3 PIG Regucalcin 0.03 0.00 0.15 1.00 1 - P09493-6 HUMAN Isoform 6 of Tropomyosin alpha-1 chain 0.13 0.23 0.35 0.97 1 - Q29307 PIG ATPase inhibitor, mitochondrial 0.76 1.01 1.01 0.76 6 - F1S9B6 PIG Uncharacterized protein (Fragment) OXA1L 1.00 0.97 0.74 1.00 1 - P60660 HUMAN Myosin light polypeptide 6 0.07 0.91 1.00 0.64 4 P12829 F1RRT2 PIG Uncharacterized protein (Fragment) MYL4 0.40 1.00 1.01 1.01 3 - A5X497 PIG Cardiac troponin I 1.00 0.97 0.96 1.02 22 P45379 I3LS66 PIG Uncharacterized protein TNNT2 0.94 0.91 1.00 1.02 24 - Q8MKF2 PIG Beta-tropomyosin (Fragment) 1.01 0.88 1.01 1.02 1 - P14632 PIG Lactotransferrin 1.00 0.97 1.00 1.01 2 - P09493-2 HUMAN Isoform 2 of Tropomyosin alpha-1 chain 0.93 0.95 1.00 1.03 1 - Q5JTV8 HUMAN Torsin-1A-interacting protein 1 1.00 0.98 1.01 1.00 1 - P09493-5 HUMAN Isoform 5 of Tropomyosin alpha-1 chain 0.17 0.93 0.95 0.74 1 O95433 F1SE06 PIG Uncharacterized protein LOC100626607 1.00 1.00 1.00 1.02 4 Q01449 F1SSF9 PIG Uncharacterized protein MYL7 0.30 1.00 0.99 0.73 3 - J3KN66 HUMAN Torsin-1A-interacting protein 1 1.00 0.99 0.99 1.02 1 - F1S698 PIG Uncharacterized protein TOR1AIP1 1.00 1.00 0.96 1.00 2 - O95433 HUMAN Activator of 90 kDa heat shock protein ATPase homolog 1 1.00 1.00 1.01 1.00 1 - Q8TCG4 HUMAN TPMsk1 (Fragment) 0.12 0.73 0.93 0.00 1 - Q719I0 HUMAN Activator of 90 kDa heat shock protein ATPase homolog 2 1.01 1.00 0.98 1.02 1 - Q92736 HUMAN Ryanodine receptor 2 1.00 0.98 1.01 1.02 5 Q9UBS4 F1SFJ8 PIG Uncharacterized protein DNAJB11 1.00 1.00 0.96 1.00 1 - P26678 HUMAN Cardiac phospholamban 1.00 1.00 1.00 1.02 1 - F1SNW4 PIG MYL3 0.01 0.87 0.93 0.00 13 - P07951 HUMAN Tropomyosin beta chain 0.10 0.70 0.90 0.00 2 - P42639 PIG Tropomyosin alpha-1 chain 0.01 0.50 0.99 0.00 35 - Q01449 HUMAN Myosin regulatory light chain 2, atrial isoform 1.00 1.00 0.99 0.45 1 - A1X899 PIG Beta-tropomyosin 0.05 0.94 0.88 0.00 11 - P05027 PIG Sodium/potassium-transporting ATPase subunit beta-1 0.84 0.96 0.92 1.01 7 Q92736 F1RHM3 PIG Uncharacterized protein (Fragment) RYR2 1.01 0.91 0.88 1.02 72 - P63317 PIG Troponin C, slow skeletal and cardiac muscles 0.35 1.00 0.74 0.00 9 - A1XQT6 PIG MLC1f 0.42 0.70 0.15 0.00 5 - F2Z5B6 PIG Tropomyosin alpha-1 chain 0.27 0.95 0.48 0.00 5 - A5X5T5 PIG Cardiac troponin I 0.01 0.00 0.00 0.00 2 Human Thin filament equivalent Accession Zq FDR No. Ac. No. No. Protein 120 1 4 7 120 1 4 7 peptides P09493-6 HUMAN Isoform 6 of Tropomyosin alpha-1 chain 0.13 0.23 0.35 0.97 1 Q9N250 PIG Titin (Fragment) 0.69 0.61 0.23 0.67 6 P42639 PIG Tropomyosin alpha-1 chain 0.01 0.50 0.99 0.00 35 K7EQW8 HUMAN Tropomyosin alpha-4 chain (Fragment) 0.05 0.70 1.00 0.07 1 Q9N251 PIG Titin (Fragment) 1.01 0.95 0.10 1.02 7 A1XQV4 PIG Tropomyosin alpha-3 chain 0.05 0.36 0.94 0.00 3 Q29117 PIG Titin (Fragment) 1.00 0.97 0.30 0.27 21 P07951 HUMAN Tropomyosin beta chain 0.10 0.70 0.90 0.00 2 Q8TCG4 HUMAN TPMsk1 (Fragment) 0.12 0.73 0.93 0.00 1 A1X899 PIG Beta-tropomyosin 0.05 0.94 0.88 0.00 11 P67936 HUMAN Tropomyosin alpha-4 chain 0.77 0.91 1.00 1.01 1 P09493-5 HUMAN Isoform 5 of Tropomyosin alpha-1 chain 0.17 0.93 0.95 0.74 1 P45379 I3LS66 PIG Uncharacterized protein TNNT2 0.94 0.91 1.00 1.02 24 Q75ZZ6 PIG Troponin T, slow skeletal muscle 1.01 0.96 0.96 1.03 2 Q8WZ42-6 HUMAN Isoform 6 of Titin 1.00 0.99 0.88 0.96 1 B3VFA9 PIG Troponin I skeletal slow-twitch protein 0.46 0.97 1.00 1.03 3 P09493-2 HUMAN Isoform 2 of Tropomyosin alpha-1 chain 0.93 0.95 1.00 1.03 1 Q8WZ42 HUMAN Titin 1.01 1.00 0.70 0.69 758 A5X497 PIG Cardiac troponin I 1.00 0.97 0.96 1.02 22 P02587 PIG Troponin C, skeletal muscle 0.72 1.00 1.00 0.85 1 F2Z5B6 PIG Tropomyosin alpha-1 chain 0.27 0.95 0.48 0.00 5 Q4JH15 PIG Troponin I 0.98 0.98 1.00 1.03 1 Q6P5Q4 F1SLY4 PIG Uncharacterized protein LMOD2 1.00 0.60 1.00 1.01 11 P63317 PIG Troponin C, slow skeletal and cardiac muscles 0.35 1.00 0.74 0.00 9 Q8MKF2 PIG Beta-tropomyosin (Fragment) 1.01 0.88 1.01 1.02 1 P79309 PIG Tropomyosin TM30-pl (Fragment) 0.99 0.99 0.96 0.75 1 Q8WZ42 I3L8Q0 PIG Uncharacterized protein 1.00 1.00 0.97 0.90 111 Q8MKF3 PIG Beta-tropomyosin (Fragment) 0.53 1.00 0.64 0.00 4 Q9N0Y9 PIG Ubiquitous tropomodulin U-Tmod 1.00 1.00 0.98 1.00 1 G0W2Z1 PIG Troponin T type 2 (Cardiac) (Fragment) 1.00 1.00 1.00 1.03 3 G8IFA6 PIG Mitochondrial NADH dehydrogenase Fe-S protein 4 1.00 1.00 1.00 1.03 1 P28289 I3LJ88 PIG Uncharacterized protein TMOD1 1.01 1.00 0.92 0.91 18 O97771 PIG Titin (Fragment) 0.57 0.53 1.00 0.35 12 P68137 PIG Actin, alpha skeletal muscle 0.73 0.65 0.99 1.03 38 P29536 HUMAN Leiomodin-1 0.70 0.68 0.84 0.84 1 A5X5T5 PIG Cardiac troponin I 0.01 0.00 0.00 0.00 2 Human Thin filament components (troponin-tropomyosin complex) equivalent Accession Zq FDR No. Ac. No. No. Protein 120 1 4 7 120 1 4 7 peptides P42639 PIG Tropomyosin alpha-1 chain 0.01 0.50 0.99 0.00 35 K7EQW8 HUMAN Tropomyosin alpha-4 chain (Fragment) 0.05 0.70 1.00 0.07 1 P45379 I3LS66 PIG Uncharacterized protein TNNT2 0.94 0.91 1.00 1.02 24 A5X497 PIG Cardiac troponin I 1.00 0.97 0.96 1.02 22 P28289 I3LJ88 PIG Uncharacterized protein TMOD1 1.01 1.00 0.92 0.91 18 Q8TCG4 HUMAN TPMsk1 (Fragment) 0.12 0.73 0.93 0.00 1 P09493-6 HUMAN Isoform 6 of Tropomyosin alpha-1 chain 0.13 0.23 0.35 0.97 1 P09493-5 HUMAN Isoform 5 of Tropomyosin alpha-1 chain 0.17 0.93 0.95 0.74 1 A1X899 PIG Beta-tropomyosin 0.05 0.94 0.88 0.00 11 P63317 PIG Troponin C, slow skeletal and cardiac muscles 0.35 1.00 0.74 0.00 9 F2Z5B6 PIG Tropomyosin alpha-1 chain 0.27 0.95 0.48 0.00 5 Q8MKF3 PIG Beta-tropomyosin (Fragment) 0.53 1.00 0.64 0.00 4 P02587 PIG Troponin C, skeletal muscle 0.72 1.00 1.00 0.85 1 P67936 HUMAN Tropomyosin alpha-4 chain 0.77 0.91 1.00 1.01 1 P09493-2 HUMAN Isoform 2 of Tropomyosin alpha-1 chain 0.93 0.95 1.00 1.03 1 A1XQV4 PIG Tropomyosin alpha-3 chain 0.05 0.36 0.94 0.00 3 Q4JH15 PIG Troponin I 0.98 0.98 1.00 1.03 1 P79309 PIG Tropomyosin TM30-pl (Fragment) 0.99 0.99 0.96 0.75 1 B3VFA9 PIG Troponin I skeletal slow-twitch protein 0.46 0.97 1.00 1.03 3 Q9N0Y9 PIG Ubiquitous tropomodulin U-Tmod 1.00 1.00 0.98 1.00 1 G0W2Z1 PIG Troponin T type 2 (Cardiac) (Fragment) 1.00 1.00 1.00 1.03 3 Q8MKF2 PIG Beta-tropomyosin (Fragment) 1.01 0.88 1.01 1.02 1 P07951 HUMAN Tropomyosin beta chain 0.10 0.70 0.90 0.00 2 Q75ZZ6 PIG Troponin T, slow skeletal muscle 1.01 0.96 0.96 1.03 2 Human Mitochondrial ribosome equivalent Accession Zq FDR No. Ac. No. No. Protein 120 1 4 7 120 1 4 7 peptides Q8N983-4 F1S8U4 PIG Uncharacterized protein MRPL43 0.00 0.01 1.00 1.02 2 I3LSY1 I3LSY1 PIG Uncharacterized protein MRPL12 0.80 0.31 0.32 0.88 1 - P52815 HUMAN 39S ribosomal protein L12, mitochondrial 0.04 0.87 0.71 1.01 1 - P82933 HUMAN 28S ribosomal protein S9, mitochondrial 1.00 0.99 0.03 0.94 1 - P82914 HUMAN 28S ribosomal protein S15, mitochondrial 0.21 0.97 0.99 1.03 2 Q9Y3B7 F1RU54 PIG Uncharacterized protein MRPL11 0.68 0.60 1.01 1.02 3 P82673 F1SG95 PIG Uncharacterized protein MRPS35 1.00 0.70 1.00 0.99 1 - F1S9B7 PIG Uncharacterized protein MRPL52 1.00 1.00 0.92 1.02 1 Q96EL2 F1ST79 PIG Uncharacterized protein MRPS24 1.00 0.92 1.00 1.03 1 - F1SL55 PIG Uncharacterized protein MRPS22 1.00 1.00 1.00 1.01 1 - Q767K8 PIG 28S ribosomal protein S18b, mitochondrial 0.70 1.00 0.99 0.68 1 - F1RK59 PIG Uncharacterized protein MRPL40 0.75 0.95 1.00 0.97 3 - F1S8A5 PIG Uncharacterized protein MRPS26 1.01 0.96 1.01 1.02 2 - F1SRT1 PIG Uncharacterized protein MRPS11 1.00 1.00 0.96 1.00 1 P82909 I3LQ99 PIG Uncharacterized protein MRPS36 1.00 0.91 0.96 1.01 5 - F1RWJ0 PIG Uncharacterized protein MRPL10 0.99 1.00 1.00 1.03 1 - F1S8G3 PIG Uncharacterized protein MRPS33 0.90 0.86 0.83 1.02 1 Human Fibrillar collagen equivalent Accession Zq FDR No.