MONDAY SCIENTIFIC SESSION LISTING:261–437 Washington, DC Nov. 11–15 Complete Session Listing Monday AM LECTURE Walter E. Washington Convention Center SYMPOSIUM Walter E. Washington Convention Center 261. Neural Circuits Controlling the Selection and 263. ● Assembly and Maintenance of the Peripheral Nerve Persistence of Sensory Information — CME Node of Ranvier in Development, Health, and Disease — CME Mon. 8:30 AM - 9:40 AM — Hall D Speaker: T. MOORE, Stanford Univ. and Howard Hughes Mon. 8:30 AM - 11:00 AM — 146A Med. Inst. Chair: H. J. WILLISON The processing and retention of sensory input is influenced Co-Chair: P. J. BROPHY by a number of endogenous factors, such as arousal, Nodes of Ranvier are the sites of saltatory conduction, motivation, and cognitive control. These factors appear to a fundamental adaption of myelinated axons. Our constrain the sensory information guiding adaptive behavior. understanding of the molecular organization of the nodal AM Mon. This lecture will discuss recent evidence on the neural region has rapidly advanced. Many components have been circuits involved in the modulation, filtering, and persistence identified, as have the interactions among the axonal and of sensory information and their relation to basic cognitive glial molecules, accounting for the specialized features of functions such as attention and working memory. The lecture nodal, paranodal, and juxtaparanodal domains. Human will include evidence from a range of model systems and autoimmune neuropathies are diseases that target glial approaches, as well as a discussion on the relevance to and axonal nodal proteins and glycolipids, leading to mental disorders. nodal disruption and conduction block. The symposium will comprise a broad overview of this area, including descriptions of the latest research findings from presenters’ SYMPOSIUM Walter E. Washington Convention Center laboratories. 262. Impact of Zika Virus Infection in the Nervous System 8:30 263.01 Introduction. and Its Underlying Mechanisms — CME 8:35 263.02 Role of myelinating glia in the organization of the nodes of Ranvier. E. PELES. Weizmann Inst. of Sci. Mon. 8:30 AM - 11:00 AM — Ballroom A 9:10 263.03 Juxtaparanodal function at the nodal complex in Chair: G. MING health and disease. C. FAIVRE-SARRAILH. CNRS UMR Co-Chair: N. SESTAN 7286, Aix Marseille Univ. The World Health Organization declared a public health emergency of international concern on Feb. 1, 2016, due to 9:45 263.04 Assembly of PNS nodal complexes. P. J. BROPHY. a potential link between Zika virus and microcephaly and/ Univ. of Edinburgh. or other neurological diseases. This symposium will discuss 10:20 263.05 ● Glycolipids at PNS nodes in Guillain-Barre recent advances in our understanding of how Zika virus syndrome. H. J. WILLISON. Univ. of Glasgow. impacts nervous system development and the underlying mechanisms using different model systems, including 10:55 263.06 Closing Remarks. human fetal tissue, human pluripotent stem cell-derived organoids and neurospheres, and animal models. MINISYMPOSIUM Walter E. Washington Convention Center 8:30 262.01 Introduction. 8:35 262.02 Brain organoids for modelling human brain 264. Neuroscience of Maternal Psychopathology — CME development and Zika infection. G. MING. Univ. of Mon. 8:30 AM - 11:00 AM — Ballroom B Pennsylvania. Chair: J. PAWLUSKI 9:10 Mechanisms of Zika induced neuronal death in the 262.03 Co-Chair: J. S. LONSTEIN developing and mature brain. J. GLEESON. UCSD. Motherhood involves striking structural and chemical 9:45 262.04 Zika virus impairs molecular fingerprinting in neural neuroplasticity, which is associated with increased stem cells. P. P. GARCEZ. Federal Univ. of Rio de Janeiro. susceptibility to anxiety and depression. These disorders 10:20 262.05 Mechanisms underlying Zika virus-related have unique profiles of neural activation when experienced neurodevelopmental defects. N. SESTAN. Yale Univ. Sch. of postpartum, and because the underlying systems overlap Med. with those for caregiving, mother-infant interactions can be disrupted. Therefore, there is intricate interplay among 10:55 262.06 Closing Remarks. maternal mental health, the mother-infant relationship, and neurobiological mechanisms mediating them. 8:30 264.01 Introduction. 8:35 264.02 Pregnancy and maternal attachment are associated with long-lasting changes in human brain structure. E. HOEKZEMA. Leiden Univ. 8:55 264.03 Motherhood, stress and SSRIs: Effects on hippocampal plasticity during pregnancy and the postpartum period. J. PAWLUSKI. Univ. of Rennes 1. • Indicated a real or perceived conflict of interest, see page 145 for details. Indicates a high school or undergraduate student presenter. Neuroscience 2017 | Monday AM | 1 * Indicates abstract’s submitting author 9:15 264.04 Motherhood and reproductive state influence MINISYMPOSIUM Walter E. Washington Convention Center central serotonin systems involved in postpartum mental illness. J. S. LONSTEIN. Michigan State Univ. 266. Open-Source Hardware for Neuroscience Research — CME 9:35 264.05 The neural correlates of responsiveness to infant pictures: A comparison of depressed and nondepressed Mon. 8:30 AM - 11:00 AM — 145B mothers and non-mothers. A. DUDIN. McMaster Univ. Chair: A. KRAVITZ 9:55 264.06 Gestational stress effects on the postpartum Neuroscientists often invent new devices to further their reward system: Implications for mood and mothering. B. experiments. In recent years, neuroscientists have published LEUNER. Ohio State Univ. several open-source inventions that rival commercial solutions. In this minisymposium, attendes will learn 10:15 264.07 Maternal neglect and anxiety involve CRF from the creators of six open-source projects, including receptors in the bed nucleus of the stria terminalis. O. a head-mounted mini-microscope, a high-channel count BOSCH. Univ. of Regensburg. electrophysiology system, multiple operant behavioral 10:35 264.08 Closing Remarks. systems, and novel experiment control software, all of which are freely available to be built, used, and modified. 8:30 266.01 Introduction. MINISYMPOSIUM Walter E. Washington Convention Center 8:35 266.02 New generation open source miniaturized 265. Beyond Place Cells: Recent Surprises From microscopes for imaging during behavior. P. GOLSHANI. Hippocampal Neurophysiology — CME UCLA. Mon. 8:30 AM - 11:00 AM — Ballroom C 8:55 266.03 Feeding Experimentation Device (FED): An open- source system for measuring food intake in rodents. K. P. Chair: M. R. MEHTA NGUYEN. Carnegie Mellon. Hippocampal neurons show spatially selective responses, 9:15 266.04 An open source device for operant licking in rats. termed place cells. The minisymposium will highlight recent H. CHEN. Univ. Tennessee Hlth. Sci. Ctr. advances that elucidate the mechanisms governing place cells and demonstrate hippocampal responses beyond 9:35 266.05 Open ephys: An open source system for allocentric spatial selectivity or place cells. These insights electrophysiology. J. VOIGTS. MIT. are obtained using diverse species — mice, rats, bats, and 9:55 266.06 An open platform for real-time control of trial-based primates — and range of behavioral, physiological, and behavioral tasks. J. SANDERS. Sanworks LLC. computational techniques. The results provide significant new insights about hippocampal function. 10:15 266.07 Bonsai: A visual programming language for the rapid prototyping of neuroscience experiments. G. LOPES. 8:30 265.01 Introduction. Sainsbury Wellcome Ctr. 8:35 265.02 Temporal lobe activity in nonhuman primates: 10:35 266.08 Closing Remarks. Locomotion versus restraint. C. A. BARNES. Univ. of Arizona. 8:55 265.03 Spatial representation of self and others in the MINISYMPOSIUM Walter E. Washington Convention Center hippocampus of bats. N. ULANOVSKY. Weizmann Inst. of Sci. 267. Modulation of Spinal Motor Networks: New Perspectives in the Control of Movement — CME 9:15 265.04 Object-vector cells and position coding in the medial entorhinal cortex. E. MOSER. Kavli Inst. Systems Mon. 8:30 AM - 11:00 AM — 151B Neurosci. Chair: P. J. WHELAN 9:35 265.05 From virtual reality to reality: How neurons make memorable maps. M. R. MEHTA. Univ. of California at Los Over the past decade technological advances have provided Angeles (UCLA). tools to identify and activate circuits within the brain and spinal cord. This has led to conceptual advances in our 9:55 265.06 Circuit mechanisms of CA1 place fields. J. C. understanding of network connectivity and intracellular MAGEE. Howard Hughes Med. Inst. properties that contribute to rhythmogenesis. This minisymposium will explore these findings, including in 10:15 265.07 Mapping of a non-spatial dimension by the topics ranging from the descending control of locomotion to hippocampal-entorhinal circuit. D. ARONOV. Columbia Univ. an understanding of changes in pacemaker cells following 10:35 265.08 Closing Remarks. spinal cord injury. 8:30 267.01 Introduction. 8:35 267.02 Activity-dependent regulation of spinal motor networks by sodium-potassium pumps. G. MILES. Univ. of St. Andrews. 8:55 267.03 Contribution of DSCAM in the normal development of motor circuits. F. BRETZNER. Univ. Laval. 9:15 267.04 Contribution of non-linear firing behaviors in locomotor function and dysfunction. F. BROCARD. Inst. de Neurosciences de la Timone. 9:35 267.05 Light on a sensory interface linking cerebrospinal fluid to motor circuits in vertebrates. C. WYART.Inst. Cerveau Et Moelle Epiniere. 2 | Society for Neuroscience • Indicated a real or perceived conflict of interest, see page