Daphnia orthology gene groups with over-abundances compared to insects Notes: Gene_Group documentation is at http://insects.eugenes.org/arthropods/; Gene_Class is a consensus functional annotation of genes in this group; Description is a consensus description of the genes; Groups with limited annotations (hypothetical) were excluded from this list. Daph column is gene count for Daphnia, * mark is for nDaph > Insects with significance p < 0.01 using chi-square test, others are groups with 2+ Daphnia genes for 1- 1 Insect genes. dPI column lists protein percent identity mean, and maximum in the group. iAve, iMax are average, maximum other (insect) gene counts for the group; marks of ^Aphid indicate overabundant group shared with Aphid Gene Group Daph dPI iAve iMax Gene_Class Description ARP1_G1539 2 88 0.9 1 ABC_transporter ATP-binding cassette sub-family F member 1 ^Aphid ARP1_G1456 2 56 1 2 Abhydrolase conserved hypothetical protein ^Aphid ARP1_G360 15* 45/70 1.3 4 Abhydrolase lysosomal acid lipase ^Aphid ARP1_G2060 2 94 1 1 Acetyl coA-transferase 4-Hydroxybutyrate CoA-transferase ARP1_G2713 2 100 0.9 1 acetylcholinesterase membrane anchor CutA homolog conserved hypothetical protein ARP1_G1507 2 69 1 1 acetylgalactosaminidase alpha-galactosidase/alpha-n-acetylgalactosaminidase ^Aphid ARP1_G187 4 25/30 2.8 3 actin binding beta chain spectrin ARP1_G236 20* 52/95 1.6 3 Acyl_transf conserved hypothetical protein ARP1_G1343 4 72/97 1.1 2 acyl-CoA binding peroxisomal 3,2-trans-enoyl-CoA isomerase ARP1_G331 8 81/100 1.8 2 acyl-CoA binding acyl-CoA-binding protein ARP1_G1582 2 36 1.2 2 acyl-CoA dehydrogenase short-chain specific acyl-CoA dehydrogenase ARP1_G1760 3 48/57 1 1 Acyltransferase 1-acylglycerol-3-phosphate acyltransferase ARP1_G1989 3 57/76 1 2 Adenylate cyclase adenylate cyclase ^Aphid ARP1_G2596 2 100 0.9 1 Adenylate cyclase conserved hypothetical protein ^Aphid ARP1_G1070 4 59/69 1.1 2 ADH_short short-chain dehydrogenase ARP1_G1638 5 74/91 1 2 ADH_short dehydrogenase/reductase SDR family member 4 ARP1_G1957 2 62 1.1 2 ADH_short dehydrogenase/reductase SDR family member 7 ARP1_G3060 2 99 1 1 ADH_short short-chain dehydrogenase ^Aphid ARP1_G3360 3 76/85 1.1 2 ADH_short short-chain dehydrogenase ARP1_G5899 2 39 0.9 1 ADH_short GA21392-PA ARP1_G6031 4* 57/63 0.5 4 ADH_short Carbonyl reductase ^Aphid ARP1_G732 3 58/62 1.1 2 ADH_short steroid dehydrogenase ARP1_G9451 5* 49/59 0 1 ADH_short Steroid dehydrogenase ARP1_G3110 2 61 0.8 1 Adiponectin receptor adiponectin receptor protein 2 ARP1_G4686 2 99 1.1 2 alanine-glyoxylate transaminase Alanine-glyoxylate aminotransferase ARP1_G2324 3 96/98 1 1 Alcohol dehydrogenase class 3 alcohol dehydrogenase class 3 ARP1_G4324 2 80 0.9 1 Aldedh aldehyde dehydrogenase 7 family ARP1_G944 4 89/93 1.1 2 Aldedh pyrroline-5-carboxylate dehydrogenase ARP1_G1087 2 98 1.3 2 allatostatin receptor allatostatin C receptor 2 CG13702-PB ARP1_G1055 3 64/69 1.2 2 Alpha_L_fucos plasma alpha-L-fucosidase ARP1_G1408 2 77 1.1 2 amidase amidase ARP1_G5562 2 28 0.9 1 Amidohydro_1 CyPIN guanine aminohydrolase family (cpin-1) ARP1_G1329 2 71 1 1 amino acid and derivative metabolic processaromatic-L-amino-acid decarboxylase ARP1_G947 4 60/80 0.8 1 Amino acid transporter proton-coupled amino acid transporter 1 ARP1_G4427 2 99 1 1 aminolevulinate synthase 5-aminolevulinic acid synthase ARP1_G12942 3* 53/55 0 1 ammonium transporter Ammonium transporter (ISS) ARP1_G3342 2 65 1 1 Ammonium_transp Rh-like protein ARP1_G1292 3 76/78 1 1 AMP-binding long-chain-fatty-acid coa ligase ARP1_G399 12* 59/98 1.4 3 AMP-binding AMP dependent coa ligase ARP1_G793 4 48/60 1.5 3 AMP-binding amp dependent coa ligase ARP1_G538 3 72/78 1.1 2 AMP-binding long-chain-fatty-acid coa ligase ARP1_G3452 3 67/69 0.8 1 Ancient conserved domain ancient conserved domain protein 2 (cyclin m2) ARP1_G2783 2 83 1.1 2 Arfaptin islet cell autoantigen 1 ARP1_G1181 3 44/58 1 1 Arrestin conserved hypothetical protein ^Aphid ARP1_G222 16* 51/96 2.1 5 Astacin zinc metalloproteinase nas-14 ARP1_G8409 4* 72/76 0.3 2 Astacin zinc metalloproteinase dpy-31 ARP1_G804 2 na 1 1 ATP-binding cassette sub-family D memberATP-binding 2 cassette sub-family D member 1 ARP1_G1932 2 96 1 1 ATPase conserved hypothetical protein ^Aphid ARP1_G195 15* 59/89 2.2 4 ATPase abc transporter ARP1_G203 11* 60/83 2 3 ATPase ATP-binding cassette sub-family G member 4 ARP1_G2163 2 89 1.1 2 ATPase ATP-dependent Clp protease ATP-binding subunit clpX ARP1_G890 2 91 1 1 ATPase mitochondrial atp synthase b chain ^Aphid ARP1_G964 3 57/80 1.1 2 acetylhexosaminidase beta-N-acetylglucosaminidase ARP1_G2899 3 87/89 1 1 binding tetratricopeptide repeat protein 1 ARP1_G794 2 82 1 2 binding importin beta-2 ARP1_G2288 2 43 1 1 Biotin_lipoyl dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase ARP1_G870 5 58/72 1.1 2 bombesin receptor subtype-3 bombesin receptor subtype-3 ^Aphid ARP1_G2258 2 99 1.1 2 Brix domain brix domain-containing protein 2 ARP1_G4778 2 99 0.8 1 Calcitonin gene-related peptide-receptor componentcalcitonin proteingene-related peptide-receptor component protein ARP1_G5840 2 85 0.9 1 calcium channel dihydropyridine-sensitive l-type calcium channel ARP1_G1199 2 31 1.2 2 calcium ion binding fibrillin 2 ARP1_G4096 3 58/70 0.9 1 calcium ion binding nadph oxidase ARP1_G4617 2 36 1 1 calcium ion binding fibulin 1 and ARP1_G970 4 72/98 1.3 2 calcium ion binding calcyphosine-like protein ARP1_G889 3 50/78 1.1 2 calcium ion transport Na/Ca exchange protein don gilbert Page 1 3/27/09 Daphnia orthology gene groups with over-abundances compared to insects Gene Group Daph dPI iAve iMax Gene_Class Description ARP1_G640 2 100 0.9 1 cAMP-dependent protein kinase regulator camp-dependent protein kinase type i-beta regulatory subunit ARP1_G152 20* 52/89 2.5 4 Carb_anhydrase Carbonic anhydrase 2 CG6906-PA ARP1_G441 15* 96/100 0.9 2 Carb_anhydrase carbonic anhydrase ARP1_G3593 2 57 1 1 Carb_anhydrase putative cytoplasmic carbonic anhydrase ARP1_G1682 2 35 1.1 2 carbohydrate metabolic process conserved hypothetical protein ARP1_G4691 2 91 1 1 carboxylic acid metabolic process Glutamate decarboxylase-like 1 ARP1_G630 2 na 1.1 2 caspase activation disulfide oxidoreductase ARP1_G1803 2 44 1.2 2 catalytic isochorismatase domain-containing protein 2 ARP1_G3515 2 99 1 1 catalytic conserved hypothetical protein ARP1_G1018 2 45 1.3 2 Cation efflux protein cation efflux protein/ zinc transporter ^Aphid ARP1_G3858 2 98 1 1 CCAAT-box-binding transcription factor conserved hypothetical protein ARP1_G702 2 36 1.1 2 cell cycle arrest Short stop/Kakapo long isoform ARP1_G402 3 43/56 2 2 Chitin synthase Chitin synthase variant 1 ARP1_G1754 4 78/100 1.1 2 Chitin_bind conserved hypothetical protein ARP1_G3063 2 63 1 1 Chitin_bind conserved hypothetical protein ARP1_G647 19* 39/100 0.2 1 Chitin_bind prenylcysteine oxidase 1 ARP1_G831 9* 57/96 0.6 2 Chitin_bind peritrophic membrane chitin binding protein ARP1_G581 4 62/77 1.2 2 Chloride channel chloride channel protein 2 ARP1_G3158 6* 46/71 0.6 2 Chloride channel ca-activated chloride channel protein ARP1_G3355 2 na 1 1 cholesterol transporter putative cholesterol transporter BmStart1 ARP1_G1191 2 46 1 1 Choline_kinase choline/ethanolamine kinase ARP1_G2585 2 98 1 1 Chondroitin synthase chondroitin synthase ARP1_G3822 2 100 1 1 Chromatin accessibility complex protein 1histone-fold protein CHRAC subunit ARP1_G4566 2 80 1 1 Chromatin assembly chromatin assembly factor i P60 subunit ??Aphid/Daph ARP1_G5454 4 58/82 0.7 1 Chromatin assembly conserved hypothetical protein ARP1_G2475 2 61 1 2 Chromodomain heterochromatin protein 1 alpha ^Aphid ARP1_G1301 4 94/99 1 1 Chromosome region maintenance chromosome region maintenance protein 1/exportin ARP1_G5080 2 58 0.8 1 Cl_peroxidase_N presqualene diphosphate phosphatase ^Aphid ARP1_G2893 2 99 1 1 Cleavage and polyadenylation cleavage and polyadenylation specificity factor subunit 3 ??Aphid/Daph ARP1_G888 3 100/100 1 1 Coiled-coil domain conserved hypothetical protein ARP1_G4616 2 96 1 1 coupled to transmembrane m... ATP-binding cassette sub-family B member 10 ARP1_G245 12* 64/99 2.1 4 CRAL_TRIO CRAL/TRIO domain-containing protein ??Aphid/Daph ARP1_G407 4 51/66 1.4 2 CRAL_TRIO CRAL/TRIO domain-containing protein ARP1_G177 27* 48/83 1 2 CRAL_TRIO_N CRAL/TRIO domain-containing protein ARP1_G2956 2 91 1 1 Crossover junction endonuclease EME1 conserved hypothetical protein ARP1_G1749 3 53/68 0.8 1 Crust_neurohorm prepro ion transport-like peptide ARP1_G3715 2 100 1 1 Cuticle SGT1 protein homolog ecdysoneless ARP1_G49 82* 65/100 0.9 1 Cuticle Cuticular protein 146; RR-2 family ??Aphid/Daph ARP1_G88 39* 83/100 2.5 8 Cuticle pupal cuticle protein 78E ARP1_G2401 2 83 1 1 Cyclin g cyclin g ARP1_G769 2 95 1.3 2 Cysteine synthase Squamous cell carcinoma antigen ^Aphid ARP1_G2266 2 79 1 2 cytidine deaminase cytidine deaminase ARP1_G276 2 na 0.9 1 Cyt_P450 Cytochrome P450 18a1 (CYPXVIIIA1) ARP1_G219 13* 52/100 2.4 5 Cyt_P450 cytochrome P450 CYP15A1 ARP1_G5951 10* 63/89 0 0 Cyt_P450 Cytochrome P450 3A14 ARP1_G2399 2 na 1.1 2 Deadenylation factor EDEN-BP deadenylation factor EDEN-BP ARP1_G315 3 47/64 2 2 Dehalogen_hydro phospholipid-transporting atpase 1 ^Aphid ARP1_G7467 5* 87/99 0.3 1 DENN domain-containing protein 2B suppression of tumorigenicity 5 ARP1_G1509 2 44 1 1 DNA topoisomerase DNA topoisomerase 2-binding protein 1 ^Aphid ARP1_G1272 5 75/100 1 1 DNA topoisomerase II DNA topoisomerase/gyrase ARP1_G1127 2 71 1 1 DNA unwinding during replication High mobility group protein DSP1 ARP1_G2361 2 na 0.9 1 DNA_helicase ATP-dependent DNA helicase recQ ??Aphid/Daph ARP1_G5200 2 96 0.9 1 Dynactin 4 protein dynactin 4 protein ARP1_G878 8* 83/99 1 2 Dynein intermediate chain 3 dynein intermediate chain 2 ^Aphid ARP1_G1239 3 66/82 0.9 1 EF_hand_Ca_bd paramyosin ^Aphid ARP1_G4626 2 97 1 1 efhand supercoiling factor ARP1_G1054 3 59/75 1.4 2 electron transport peroxisomal N1-acetyl-spermine/spermidine oxidase ARP1_G2168 2 35 1.1 2 EMP70 transmembrane 9 superfamily protein member 3 ARP1_G347 9* 57/88 1.9 4 Endonuclease deoxyribonuclease I ARP1_G2051 2 37 1.1 2 endopeptidase spermatogenesis associated factor ARP1_G1729 2 na 1 1 epidermal growth factor receptor signalingpole ..