M070825 SLITRK6 Antibody Order 021-34695924 [email protected] Support 400-6123-828 50ul [email protected] 100 uL Web www.abmart.cn Description: SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit. Uniprot: Q9H5Y7 Alternative Names： 4832410J21Rik; neuronal transmembrane protein Slitrk6; RP11-272M24.2; SLIT and NTRK- like family, member 6; SLIT and NTRK-like protein 6; slit and trk like gene 6; 4832410J21Rik; DFNMYP; SLITRK6; Sltk6; Specificity: SLITRK6 Antibody detects endogenous levels of total SLITRK6. Reactivity: Human, Mouse, Rat, Monkey Source: Mouse Mol.Wt.: 95kDa(Calculated); Storage Condition: Store at -20 °C. Stable for 12 months from date of receipt. 1 For in vitro research use only and not intended for use in humans or animals. Application: WB 1:1000-1:2000; IHC/IF 1:100-1:1000; FC 1:100-1:200 Immunohistochemical analysis of SLITRK6 staining in human human lung carcinoma formalin fixed paraffin embedded tissue section, using SLITRK6 antibody. 2 For in vitro research use only and not intended for use in humans or animals. .