RESIDENT SCHOLARLY WORK Process Improvement 2020-2021 CPIP Curriculum Ongoing Projects: Alexander Gavralidis, Stephanie tin, Matthew Macey, Allisa Alport, Beenish Furquan, Justin Byrne • Unnecessary laboratory draws in patients at a Community Hospital - evaluating whether inpatients at Salem Hospital staying overnight for a social reason undergo unnecessary laboratory draws Daria Ade, Mayuri Rapolu, Usman Mughal, Eva Kubrova, Barbara Lambl, Patrick Lee • Procalcitonin utilization to tailor antibiotic use at Salem Hospital- part of Antibiotic Stewardship program Sneha Lakshman, Arturo Castro, Ashley So, George Kavalam, Hassan Kazmi, Daniela Urma, Patrick Gordan • Development of a standardized ultrasound guided central venus catheter insertion curriculum Nupur Dandawate, Farideh Davoudi , Usama Talib, Patrick Lee • Inpatient Echo utilization – guidelines updates Anneris Estevez, Usmam Mughal, Zach Abbott, Evita Joseph, Caroline Cubbison, Faith Omede, Daniela Urma • Decrease health disparities for Hispanic community at Lynn NSPG by standardizing diabetes education referral patterns and patient education Imama Ahmad, Usama Talib, Muhammad Akash, Pablo Ledesma, Patrick Lee • Inpatient Telemetry Utilization Usman Mughal, Anneris Estevez, Patrick Lee, Barbara Lambl • Health Disparities & Covid-19 Impact on Minorities, sponsored by Dr. Patrick Lee, Chair of Medicine, Dr. Barb Lambl, Infectious Disease 2017-2020 Alexander Gavralidis, Emre Tarhan, Anneris Estevez, Daniela Urma, Austin Turner, Patrick Lee • Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19 – 5/2020 implementing use of Convalescent Plasma to MGB Salem hospital in collaboration with research team. Arturo Castro-Diaz, Dr. Daniela Urma • Improving Hospital Care and Post - acute Care of SARS CoV2 patients 4/2020- 8/2020 Caroline Cubbison, Sohaib Ansari, Adam Matos • Code Status Documentation for admitted patients at Salem Hospital - Project accepted to SHM national meeting to be presented in April 2020 Caroline Cubbison, Coleen Reid, Dr. Elizabeth Stevenson, • The Critical Illness Conversation, Dr. Caroline Cubbison, PGY-2, sponsored by Dr. Coleen Reid, Palliative Care, Dr. Elizabeth Stevenson, Critical Care (Journal of Critical Care Medicine, 2020) Faith Omede, Usama Talib, David Cardona • Best project implementation at COE GH Symposium- Introducing an Adapted Critical Response System to a Romanian tertiary Center. December 2019 Sara Altamimi, PGY-2, sponsored by Dr. Marc Rubin, Surgery, Dr. Barb Lambl • C.Difficile Reduction project, Dr. Sara Altamimi, PGY-2, sponsored by Dr. Marc Rubin, Surgery, Dr. Barb Lambl, Infectious Disease (J. of the American Medical Informatics Assoc, 2018; J. of the Joint Commission, 2019) David Cardona, Usama Talib, Elizabeth Stevenson • Therapeutic hypothermia in Cardiac Arrest, Dr. David Cardona PGY-2, sponsor Dr. Elizabeth Stevenson, Critical Care, 2019 Original Continuing Research 2020-2021 • Stridor retrospective review in patients with COVID: Nupur Dandawate, Sohaib Ansari, Sneha Lakshman, Alexander Gavralidis • Impact on education and wellness in the residency program due to COVID pandemic: Caroline Cubbison, Sneha Lakshman, Imama Ahmad, Nupur Dandawate • Racial and Socioeconomic outcomes in Hispanic population affected by COVID pandemic: Anneris Estevez, Usman Mughal. • Potential Barriers to Clinical Trials of New Therapeutics for Myelodysplastic Syndromes: Alexander Gavralidis • Evaluating relationships between TP53 mutation and the percentage of ring sideroblasts in the bone marrow of patients with MDS. Alexander Gavralidis • Clinicopathological Features of Lung Cancer Patients Treated with Cancer Immunotherapy: Alexander Gavralidis • Co-Founder and Clinical Lead of 'Smart Syringe' through the MGH MESH Incubator - developing a new medical device to automatically detect and document medications from syringes intraoperatively . Ashley So • Cardiovascular Outcomes and Causes of Elevated Troponin in Hospitalized Patients with COVID- 19: Impact on Mortality. Ledesma Pablo • Published Research Alexander Gavralidis, Justin Gainor (November 2020). COVID-19 Infection in a Lung Cancer Patient Population: Incidence, Presentation and Alternative Diagnostic Considerations, Retrospective single-institution evaluation of COVID-19 and its implications in patients with lung cancer , JTO Clinical and Research Reports Alexander Gavralidis, Andrew Brunner (October 2020), Novel Therapies in the Treatment of Adult Acute Lymphoblastic Leukemia, Current Hematologic Malignancy Reports Ruta Shah, Ana Maria Bensaci, Patrick Lee, Usman Mughal, caroline Cubbinson, Sophia Chan, Sohaib Ansari, April Susan, Humaira Jami, Mathew Basciota, Jade Gerbands, Vinit Oomen, Alexander Gavralidis, Alba Coraini, 10/21/2020, NEJM, Efficacy of Tocilizumab in Patients Hospitalized with Covid-19. Multi-center RCT including Salem Hospital, MGH, BWH and NWH. 2 A. Coraini, S. Lakshman; June 2020; Trick or Treat- A case of seronegative listeria meningoencephalitis; Journal of Neurology and Experimental Neuroscience (JNEN) Alexander Gavralidis, Justin Gainor, 10/2020. Immunotherapy in EGFR-Mutant and ALK-Positive Lung Cancer: Implications for Oncogene-Driven Lung Cancer. The Cancer Journal Di Capua, J., Reid, N. J., Som, A., An, T., López, D. B., So, A. J., ... & Walker, G. T. (2020). The Effect of Preoperative Renal Failure on Outcomes Following Infrainguinal Endovascular Interventions for Peripheral Arterial Disease. Journal of Vascular and Interventional Radiology. doi: https://doi.org/10.1016/j.jvir.2020.10.020. Ledesma Pablo, Gelatin Methacryloyl Bioadhesive Improves Survival and Reduces Scar Burden in a Mouse Model of Myocardial Infarction; Journal of the American Heart Association (JAHA); 05/27/2020; https://doi.org/10.1161/JAHA.119.014199 Kim, S., DeMaria Jr, S., Li, J., Lin, H. M., Smith, N., Wax, D.,A.So & Zerillo, J. (2019). Persistent acidosis after reperfusion—A prognostic indicator of increased 30-day and in-hospital postoperative mortality in liver transplant recipients. Clinical transplantation, 33(3), e13473. doi: https://doi.org/10.1111/ctr.13473. Poster and Oral Presentation • Estevez, A., Alpert, A., Lee, P. (October 2020). Ten Days of Chest Pain: A Unique Presentation of COVID-19 at a Community Hospital. Presented at Chest Annual Meeting October 2020. • Ledesma Pablo, November 13-17, 2020 , American Heart Association (AHA) Scientific Sessions Outcomes In Patients Hospitalized With Influenza-related Myocarditis In The United States: A Nationwide Study • Ledesma Pablo, November 13-17, 2020 , American Heart Association (AHA) Scientific Sessions Trends In Cardiac Implantable Electronic Device-related Infective Endocarditis In The United States: A Nationwide Study (2003-2017) • Ledesma Pablo, May 6-9, 2020; Heart Rhythm Scientific Sessions (HRS) San Diego, CA, Post-Approval Safety Outcomes of Percutaneous Left Atrial Appendage Closure with Watchman Device: An Analysis of The FDA MAUDE Database From 2015 To 2019 • So Ashley, 2020: Invited Panelist for the workshop "Providers taking control: patient-centered, provider- driven innovation" as part of the 2020 3D All Levels Trauma Care (ALTC) International Conference hosted by the Kingdom of Saudi Arabia's Academy of Science • Gavralidis Alexander, Daniela Urma (September 2020), Residents drive COVID-19 Convalescent Plasma treatment in a community hospital Research abstract accepted at American College of Physicians, MA • Gavralidis Alexander (September 2020) Intraperitoneal TB – A danger lurking in the dark, Case report accepted at American College of Physicians, MA • Lakshman Sneha L.K.Gomes, J. William (October 2020): American Society of Nephrology, Catch 22: The Vicious Cycle of Malignant Hypertension and Worsening Renal Thrombotic Microangiopathy • S. Lakshman, I. Ahmad, R. Kahn CHEST October 2020 Asymmetric Myoclonus in a Patient with Non-Ketotic Hyperglycemia with baseline End Stage Renal Disease. • S. Lakshman, I. Ahmad, U. Talib. T. Carr; CHEST October 2020; HIT the Heart- A Case of Arterial and Venous Thromboemboli • U. Talib, I. Ahmad, S. Lakshma; CHEST October 2020; Angioedema Secondary to Ticagrelor: A Rare Complication • Ahmad, S. Lakshman, T. Carr; CHEST October 2020; The Autonomic Storm: A complication of Anoxic Brain Injury • S. Lakshman, S.R. Dassum, and M. Basciotta; ATS May 2020; Dissecting a Headache- a Case of Headache Secondary to Multiple Cerebellar Infarcts in the Setting of a Right Vertebral Artery Dissection • S. Lakshman, U. Talib, E. Stevenson; ATS May 2020; Clots, Clots, Clots! A Case Report of Extensive Arterial Thromboembolic Disease in the Setting of Metastatic Adenocarcinoma of the Lung in an Anti-Coagulated Patient • U. Talib , S. Lakshman; ATS May 2020; Viral Illness Precipitating Cardiac Arrest in a Patient with Congenital QT Prolongation • Coraini, S. Lakshman; Neurological Disorder Summit November 2020; Trick or Treat- A case of seronegative listeria meningoencephalitis • U. Talib, S. Lakshman, S. Ansari, Y. Monzavi, P. Gordan ( 2019) Superior Vena Cava- Right Atrial Junction Endocarditis in HIV Positive Patient with Active IV Drug Use. Circulation 2019; 140: A10105 • S. Lakshman, B. Furquan, M. Basciotta: ACP MA Chapter October 2019; Pyramid fever- A case of Fever of unknown etiology; Oral Poster Presentation • S. Lakshman, Y. Monzavi, C. Cubbison, M. Basciotta; CHEST October 2019; TB or not TB? A case of Non- tuberculous Mycobacterial Lung Disease • Cardona Estrada, David A. Shafer, K. Opotowsky, A. (May 2019). Lipid and Blood Pressure Profiles