Anti-eIF3G monoclonal antibody (DCABH-15282) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description The elF3G (eIF3-p44) is a subunit of eukaryotic translation initiation factor4(eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to280kd. elF3-p44 is constitutively expressed in many tissues, including spleen thymus, prostate, colon, ovary, etc. Immunogen A synthetic peptide of human EIF3G is used for rabbit immunization. Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A Conjugate Unconjugated Applications Western Blot (Transfected lysate); ELISA Size 1 ea Buffer In 1x PBS, pH 7.4 Preservative None Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. GENE INFORMATION Gene Name EIF3G eukaryotic translation initiation factor 3, subunit G [ Homo sapiens ] Official Symbol EIF3G Synonyms EIF3G; eukaryotic translation initiation factor 3, subunit G; EIF3S4, eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; eukaryotic translation initiation factor 3 subunit G; eIF3 delta; eIF3 p44; eIF3g; eIF3 p42; eIF-3-delta; eIF-3 RNA-binding subunit; eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3 subunit p42; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); EIF3S4; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved EIF3-P42; eIF3-p44; eIF3-delta; Entrez Gene ID 8666 Protein Refseq NP_003746 UniProt ID O75821 Chromosome Location 19p13.2 Pathway Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism- specific biosystem; Eukaryotic Translation Initiation, organism-specific bi Function RNA binding; nucleotide binding; protein binding; contributes_to translation initiation factor activity; contributes_to translation initiation factor activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.