LEGEMIDDELSTATISTIKK 2019:2 Reseptregisteret 2014–2018 The Norwegian Prescription Database 2014–2018 Reseptregisteret 2014–2018 The Norwegian Prescription Database 2014–2018 Christian Lie Berg Kristine Olsen Solveig Sakshaug Utgitt av Folkehelseinstituttet / Published by Norwegian Institute of Public Health Område for Helsedata og digitalisering Avdeling for Legemiddelstatistikk Juni 2019 Tittel/Title: Legemiddelstatistikk 2019:2 Reseptregisteret 2014–2018 / The Norwegian Prescription Database 2014–2018 Forfattere/Authors: Christian Berg, redaktør/editor Kristine Olsen Solveig Sakshaug Acknowledgement: Julie D. W. Johansen (English text) Bestilling/Order: Rapporten kan lastes ned som pdf på Folkehelseinstituttets nettsider: www.fhi.no / The report can be downloaded from www.fhi.no Grafisk design omslag: Fete Typer Ombrekking: Houston911 Kontaktinformasjon / Contact information: Folkehelseinstituttet / Norwegian Institute of Public Health Postboks 222 Skøyen N-0213 Oslo Tel: +47 21 07 70 00 ISSN: 1890-9647 ISBN: 978-82-8406-014-9 Sitering/Citation: Berg, C (red), Reseptregisteret 2014–2018 [The Norwegian Prescription Database 2014–2018] Legemiddelstatistikk 2019:2, Oslo, Norge: Folkehelseinstituttet, 2019. Tidligere utgaver / Previous editions: 2008: Reseptregisteret 2004–2007 / The Norwegian Prescription Database 2004–2007 2009: Legemiddelstatistikk 2009:2: Reseptregisteret 2004–2008 / The Norwegian Prescription Database 2004–2008 2010: Legemiddelstatistikk 2010:2: Reseptregisteret 2005–2009. Tema: Vanedannende legemidler / The Norwegian Prescription Database 2005–2009. Topic: Addicitiv drugs 2011: Legemiddelstatistikk 2011:2: Reseptregisteret 2006–2010 / The NorwegianPrescription Database 2006–2010 2012: Legemiddelstatistikk 2012:2: Reseptregisteret 2007–2011. Tema: Legemidler og eldre / The Norwegian Prescription Database 2007–2011. Topic: Drug use in the elderly 2013: Legemiddelstatistikk 2013:2: Reseptregisteret 2008–2012 / The Norwegian Prescription Database 2008–2012 2014: Legemiddelstatistikk 2014:2: Reseptregisteret 2009–2013 / The Norwegian Prescription Database 2009–2013 2015: Legemiddelstatistikk 2015:2: Reseptregisteret 2010–2014. Tema: Antibiotika / The Norwegian Prescription Database 2010–2014. Topic: Antibiotics 2016: Legemiddelstatistikk 2016:2: Reseptregisteret 2011–2015 / The NorwegianPrescription Database 2011–2015 2017: Legemiddelstatistikk 2017:2: Reseptregisteret 2012–2016 / The Norwegian Prescription Database 2012–2016 2018: Legemiddelstatistikk 2018:2: Reseptregisteret 2013–2017. Tema: Legemidler og eldre / The Norwegian Prescription Database 2010–2014. Topic: Drug use in the elderly Innhold Sammendrag ....................................................................................................................................................................... 7 1. Generelt om Reseptregisteret (NorPD) og legemiddelstatistikk ................................................................................... 8 1.1 Reseptregisteret .................................................................................................................................................... 8 1.2 Nordiske reseptregistre ...................................................................................................................................... 11 1.3 Grossistbasert legemiddelstatistikk .................................................................................................................... 12 1.4 Anatomisk Terapeutisk Kjemisk (ATC)-klassifikasjon ............................................................................................ 12 1.5 Definert Døgndose (DDD) .................................................................................................................................... 13 1.6 WHO Collaborating Centre for Drug Statistics Methodology .............................................................................. 14 2. Reseptregisteret (NorPD) 2014–2018 .......................................................................................................................... 15 2.1 Utvalgte nøkkeltall fra Reseptregisteret .............................................................................................................. 15 2.2 Reseptkategorier og refusjon av utgifter til legemidler ....................................................................................... 19 2.3 Beskrivelse av hovedtabellene ............................................................................................................................ 20 2.4 ATC main groups .................................................................................................................................................. 24 2.5 ATC group A – Alimentary tract and metabolism................................................................................................. 25 2.6 ATC group B – Blood and bloodforming organs ................................................................................................... 36 2.7 ATC group C – Cardiovascular system .................................................................................................................. 39 2.8 ATC group D – Dermatologicals ........................................................................................................................... 47 2.9 ATC group G – Genito urinary system and sex hormones .................................................................................... 53 2.10 ATC group H – Systemic hormonal preparations, excl. sex hormones and insulins ............................................. 58 2.11 ATC group J – Antiinfectives for systemic use ...................................................................................................... 61 2.12 ATC group L – Antineoplastic and immunomodulating agents ............................................................................ 68 2.13 ATC group M – Musculo-skeletal system ............................................................................................................. 71 2.14 ATC group N – Nervous system ........................................................................................................................... 74 2.15 ATC group P – Antiparasitic products, insecticides and repellents ...................................................................... 84 2.16 ATC group R – Respiratory system ....................................................................................................................... 86 2.17 ATC group S – Sensory organs ............................................................................................................................. 91 2.18 ATC-group V – Various ......................................................................................................................................... 95 Noen forkortelser og definisjoner .................................................................................................................................... 97 Folkemengde i Norge 2014–2018 (per 1. juli) .................................................................................................................. 98 Folkemengde etter alder i 2018 (per 1. juli) ..................................................................................................................... 98 Liste over vitenskapelige publikasjoner basert på data fra Reseptregisteret per 21.02.2019 ...................................... 99 Legemiddelstatistikk 2019:2 • Folkehelseinstituttet 5 Contents Summary ............................................................................................................................................................................. 7 1. General information about the Norwegian Prescription Database (NorPD) and drug statistics ................................. 8 1.1 About the NorPD ................................................................................................................................................... 8 1.2 Prescription statistics in the other Nordic countries ........................................................................................... 11 1.3 The Norwegian Drug Wholesales Statistics ........................................................................................................ 12 1.4 The Anatomical Therapeutic Chemical (ATC) classification system ..................................................................... 12 1.5 The Defined Daily Dose (DDD) ............................................................................................................................. 13 1.6 WHO Collaborating Centre for Drug Statistics Methodology .............................................................................. 14 2. The Norwegian PrescriptionDatabase (NorPD) 2014–2018 ........................................................................................ 15 2.1 Selected key figures from the NorPD................................................................................................................... 15 2.2 Prescription categories and reimbursement of medicinal expenses .................................................................. 19 2.3 Description of the main tables ............................................................................................................................ 20 2.4 ATC main groups .................................................................................................................................................