Good health starts in the gut Your Daily Challenges • Providing real benefits for consumer wellbeing • Ensuring stable and appealing tastes and textures • Enhancing the naturally healthy image of your brand Consumers are discovering that a healthy gut is much more than good digestion. The DuPont Digestive Health Platform delivers targeted solutions for the growing gut health market If there is one thing that health-conscious consumers are a gut-friendly diet looks like, one that can relieve digestive increasingly aware of, it’s that good health and wellbeing discomfort, improve immune health, and support overall often starts in the gut. The rise in food product launches weight management. An increasing amount of studies also with a digestive health claim also reflects the general point to the connection between gut health and cognitive consumer preference for naturally functional foods and health as a future growth area in the market. beverages to meet their nutritional needs. To take advantage of these opportunities, you need the For food manufacturers, the gut health market represents right product development partner. That’s where DuPont a vast opportunity to explore. Euromonitor insights predict Nutrition & Biosciences comes in. Our Digestive Health the global digestive health market will continue to maintain Platform offers the ingredient solutions, application knowhow a 5.7% CAGR in retail value up to 2023 and beyond. and regulatory support you need to capture market share. The biggest potential lies with products that are enriched The key to your success is that consumers can feel with probiotics and fiber and are free from ingredients that a difference. By drawing on our nutritional, scientific, can cause intolerance, such as gluten and lactose. This would regulatory and functional capabilities, that’s a promise your allow products to align with consumers’ perceptions of what brand can keep. Benefits and gains Your business gains Your product benefits Our proven solution • Leverage the healthy image of your • Clinically documented ingredients • Premium probiotics brand • Appealing tastes and textures • Starter cultures • Achieve premium positioning • Free-from lactose/gluten • Prebiotic fibers (polydextrose, • Benefit from extensive technical and opportunities human milk oligosaccharides) regulatory support • Stability throughout shelf life • Functional systems, emulsifiers, • Reduce your time to market enzymes & hydrocolloids Solutions overview for food and beverage applications Digestive health Health benefits obtained via the gut Food food and beverage application Gut health segments Immune health Weight management Bifido B. lactis HN019™, documented for gut comfort Dophilus Protect Adult, L. acidophilus NCFM®, Probiotic fermented Yogurt, B. lactis Bl-04™, documented for well-being & gut dairy Drinking yogurt documented for immune comfort health YO-MIX® PRO series Single probiotic strains “All in One” yogurt cultures with probiotic species Plant-based dairy Probiotic fermented Danisco® VEGE Cultures, including alternatives, plant-based food and Dophilus Fermented juices, beverages and Bifido VEGE Tea etc. Bifido Bars, Protect Adult, Other probiotic food B. lactis HN019™ Beverages, B. lactis Bl-04™ Shape and beverages Cereals Dophilus Protect Earlylife B. lactis B420™ L. acidophilus NCFM® L. Rhamnosus HN001™ CARE4U™ Human Milk Oligosaccharides Food, Litesse® polydextrose Litesse® polydextrose CARE4U™ Human Milk Fibers / prebiotics Beverages, DuPont™ Danisco® Nurica™ FORTEFIBER™ Oligosaccharides Formula FIBRIM® Soy Fiber Soluble Dietary Fiber FORTEFIBER™ Soluble Dietary Fiber DuPont™ Danisco® Bonlacta™ Lactose-free Dairy, Formula GODO YNL-2 Lactase WELLENCE™ GF 321, POWERFlex® GF 4201, PowerBake® GF 101, Functional Systems, Hydrocolloids, Baked Enzymes, Emulsifiers, Soy Proteins, Gluten-free goods Pea nuggets, Litesse® polydextrose, FORTEFIBER™ Soluble Dietary Fiber, XIVIA® Xylitol, Fermentates is a line of clinically mastered probiotic solutions from the leading industry experts at DuPont HOWARU® premium probiotics are offered as single strains or pre-formulated blends, all validated by gold-standard clinical trials. Each robust strain or strain-combination provides an array of benefits sure to meet your manufacturing needs and that of your unique customer. The Human Microbiome Venture The human microbiome comprises all the microbes that live in and on the body. In fact, there are more microbes living in the human as there are cells in the human body. These microbes produce thousands of different metabolites and are responsible for as much as 30% of the metabolites found in human blood. Academic research over the past 10 years or so has demonstrated the significant role the microbiome plays in human health and disease. To spearhead the development of new microbiome science-based solutions, DuPont Nutrition & Biosciences has established the Human Microbiome Venture (HMV). This team will complement and build upon the existing leadership of DuPont in the areas of probiotics and prebiotics, including human milk oligosaccharides (HMOs), to deliver novel intervention options that can modulate the microbiome and exert a beneficial or even a therapeutic effect. The HMV team is also engaging in strategic partnerships with other microbiome leaders in academia and in the healthcare industry to accelerate product development and future commercialization of these products. THE MICROBIOME BY NUMBERS: Tens Of Trillions Of Microbial Cells The Scientific Community A Complex Microbial Has Been Studying Ecosystem The Microbiome For >1000 Species over 20 Years 30% Of The Metabolites Millions Found In Your Blood Are Of Microbial Coming From The Genes Microbiome Producing Over 500,000 Different Metabolites Application support All our solutions for digestive health have been developed and tested in the DuPont application centers. This, together with our extensive global presence and knowledge of food products, processes and regulations, make us a strong partner for your product development needs. DuPont™, the DuPont Oval Logo, and all trademarks and service marks denoted with ™, SM or ® are owned by affiliates of DuPont de Nemours, Inc. unless otherwise noted. © 2019 DuPont. The information contained herein is based on data known to DuPont or its affiliates at the time of preparation of the information and believed by them to be reliable. This is business-to-business information intended for food, beverage and supplement producers, and is not intended for the final consumer of a finished food, beverage or supplement product. The information is provided “as is” and its use is at the recipient’s sole discretion and risk. It is the recipient’s sole responsibility to determine the suitability and legality of its proposed use of DuPont products for its specific purposes. Information and statements herein shall not be construed as licenses to practice, or recommendations to infringe, any patents or other intellectual property rights of DuPont or others. DUPONT HEREBY EXPRESSLY DISCLAIMS (I) ANY AND ALL LIABILITY IN CONNECTION WITH SUCH INFORMATION, INCLUDING, BUT NOT LIMITED TO, ANY LIABILITY RELATING TO THE ACCURACY, COMPLETENESS, OR USEFULNESS OF SUCH INFORMATION, AND (II) ANY AND ALL Nutrition & Biosciences REPRESENTATIONS OR WARRANTIES, EXPRESS OR IMPLIED, WITH RESPECT TO SUCH INFORMATION, OR ANY PART THEREOF, INCLUDING ALL REPRESENTATIONS AND WARRANTIES OF TITLE, NONINFRINGEMENT OF COPYRIGHT OR PATENT RIGHTS OF OTHERS, MERCHANTABILITY, FITNESS OR SUITABILITY FOR ANY PURPOSE, PB 114-1 www.food.dupont.com AND WARRANTIES ARISING BY LAW, STATUTE, USAGE OF TRADE OR COURSE OF DEALING..