NYU The Magazine of new York UniversiPhTY school of MedicineYsiciafall 2010N volume 62 • No. 1 k i d s S i x S torie S o f t h e S p ecial care they needed— and received. pluS t he caSe of the one-Sided clock highlightS of recent reSearch talking about infertility with david keefe 47172 Cover_Fall V1.indd 2 10/29/10 2:14 PM Help Us Make Dreams Come True Ev Ery aspiring physician drEams of thE day somEonE will makE a gift onlinE call him or hEr “doctor” for thE first timE. But getting there Please visit www.nyu.edu/alumni. takes a lot more than hard work and dedication—it takes resources. By contributing to the NYU School of Medicine Alumni Campaign, you help To discuss special ensure that our next generation of physicians will have access to the best giving opportunities, teaching and research, along with a competitive financial assistance package. call Anthony J. Grieco, MD, Associate Dean for Alumni Relations, When you make a gift, you help us guarantee that all of our students will at 212.263.5390. have the means to complete our rigorous education. One day, you may even have the privilege of addressing them yourself as “Doctor.” Thank you for your generosity. 47172 pIFC FrontPg Ad V1.indd 1 10/29/10 2:27 PM The MagaziNe of New York UNiversiTY school of MediciNe fall 2010 VOluME 62 nO. NYUS PhY iciaN 1 New York University “ oUr greateSt Martin lipton, esq. Chairman, treaSUre iS oUr Board of Trustees childreN.” John sexton President r obert i. groSSmaN, md, deaN aNd ceo robert Berne Exective Vice President for Health NYU Langone• Medical Center c over StorieS kenneth g. langone Chairman, Board of Trustees S ix kidS aNd the SPecial care theY Needed robert i. grossman, Md Dean and Chief Executive Officer 08 chaNge of heart Sometimes babies are born deborah loeb Bohren with arteries that arise from the Vice President, wrong places. Communications and Public Affairs 12 In Pediatric SUrgerY, • leSS iS more Minimally NYU PhYsiCiaN invasive surgery, once reserved for s teven B. abramson, Md adults, is now for children, too. anthony J. grieco, Md (’63) it’ S aboUt more thaN Editors, Science d ePartmeNtS 16 and Medicine how YoU look Repairing cleft lip and palate. frank w. lopez 02 From the Dean Managing Editor Children’s Stories 18 life oN a bUbble Marjorie shaffer How Many Kids Get Sick from That? Growing up with HIV. Senior Editor 03 s upport 20 back iN the game royce flippin Q&A with Gary Cohn, new chair of HJD Advisory Board Coming back from a brain Contributing Editor hemorrhage. rob hewitt 04 News from Medicine Art Director Tracking Early-Onset Alzheimer’s 22 StaYiNg healthY New Clues to Elusive HIV Vaccine School-based clinics sherry zucker make a difference. Print Production MicroRNA Found that Regulates Cholesterol Coordinator Tanning Salon Rays Linked to Melanoma ed atkinson 24 Faculty Conversation Talking about infertility with Copy Editor David Keefe, new chair of obstetrics and gynecology On C THE OVEr•: 26 Medical Mystery: PHOTOgrAPH By The Case of the One-Sided Clock Sasha Nialla NYUThe Magazine of new York UniversiTYPhYsiciaN school of Medicine fall 2010 28 a lumni Profile volume 62 • No. 1 k i d s Six StorieS of the Special care they needed— Steven Smith (’74) serves a small community in rural Florida and received. 30 Faculty News Glenn Saxe Named Chair of Child and Adolescent Psychiatry pluS the caSe of the one-Sided clock highlightS of recent reSearch talking about Moses Chao is President-elect of Society of Neuroscience infertility with david keefe Martin Blaser Awarded NIH Grant for Innovative Research Urothelial Biology Team Receives $8.2 Million NIH Award ToU o r readers Stem Cell Grant to Expand RNAi Core Facility Beginning with this issue, NYU Physician is available 32 Obituaries for iPad users. Download Aaron Rausen, Jean-Claude Bystryn it free from the App Store. photographs top and bottom left and bottom right: elizabeth weinberg; others: sasha nialla NYU PhYsiciaN fall 2010 1 47172 p1 TOC V2.indd 1 10/29/10 2:18 PM Message from the Dean & CEO Children’s h ow Many Kids Stories Get sick from That? NYU LaNgoNe MediCaL CeNter has enjoyed 10,730 Estimated number of new cases of a long association with pediatrics ever since cancer diagnosed in 2009 in children a children’s clinic at Bellevue Hospital was ages 0-14 years. established in 1874 by dr. abraham Jacobi, who Source: national Cancer institute served on the NYU School of Medicine faculty and is considered the father of american 30,000 pediatrics. the clinic was the first of its kind in Number of children and adults in the U.S. with cystic fibrosis, more than half of the United States. Most of this issue of whom are under the age of 18. NYU Physician is dedicated to stories about Source: Cystic Fibrosis Foundation children, who hold a special place in our community. although each story is unique, the 45,000 unusual courage and determination of these Number of children under age of 15 in children—and their parents—is a recurrent theme, serving as an the U.S. who annually develop epilepsy. inspiration to all of us. SourceS: Epilepsy Foundation these stories also demonstrate the dedication and compassion of our physicians, surgeons, rehabilitation therapists, nurses, and other 17% Proportion of children between ages of healthcare providers to ensure that these special patients receive the 12 and 19 who are obese. best care. there is truly an outstanding range of specialty services Source: Centers for Disease Control and for children at NYU Langone Medical Center, from the neonatal Prevention intensive care unit where the sickest newborns receive care, to the surgical suites where complex congenital heart defects are repaired, 12.8% to the Stephen d. Hassenfeld Children’s Center for Cancer and Blood Percentage of infants born prematurely in U.S. each year. disorders where children with acute lymphoblastic leukemia and Source: March of Dimes other cancers Nreceive the most advanced treatments. our Hospital for Joint diseases (see article on facing page), one of o ne in 125 the leading specialty hospitals in the nation, provides world-class Rate of children born with congenital pediatric specialty care through its Center for Children. the center heart defects each year. Source: Hoffman JiE and Kaplan s. J Am Coll treats a wide range of musculoskeletal problems in children, ranging Cardiol 29 (2002): 1890-1900. from trauma and fracture, to sports-related injuries in children and adolescents, to neuromuscular disorders and cerebral palsy. o ne in 303 our greatest treasure is our children. i am proud to report that Rate of children born each year with with the support of our philanthropic community, including KidS cerebral palsy. of NYU, we are now laying the groundwork for a new state-of-the- Source: Centers for Disease Control and art children’s hospital and we are continuing to hire new faculty Prevention in pediatric subspecialty fields. the future of children’s healthcare appears brighter than ever, and NYU Langone will certainly be part 7,805 Number of pediatric discharges under of that story. • 18 years old from NYU Langone Medical Center in FY2009. Source: nYU Langone Medical Center 46,957 Dea N & ceo rObErt i. grOssMan, MD Number of pediatric outpatient visits at NYU Langone Medical Center in FY2009. Source: nYU Langone Medical Center • NYU PhYsiciaN 2 fall 2010 47172 p2-3 AroundCamp V2.indd 2 10/29/10 2:18 PM support Q& a With Gary cohn New chair of the advisory Board for NYU hospital for Joint Diseases garY CoHN, who was recently named chair of the advisory board of Hospital for Joint diseases, is president and chief operating officer of goldman Sachs, one of the most prestigious financial institutions in the United States. He and his wife, Lisa Pevaroff Cohn, were founding advisory board members of the NYU Child Study Center and also funded the Pevaroff Cohn Professorship in Child and adolescent Psychiatry at the NYU School of Medicine in 1999. He has also been a member of the NYU Langone Medical Center’s Board of trustees since 2000. the couple reside with their three daughters in Manhattan. Hospital for Joint diseases, founded in 1905, is one of five specialty hospitals in the world devoted to musculoskeletal care. affiliated since 1994 with NYU Langone Medical Center, it was fully merged into the Medical Center in 2006. NYU PHYSICIAN: What drew you to the Hospital causes and cures of rheumatologic for Joint Diseases? and musculoskeletal diseases. We’re GARY COHN: one of the things we pride hoping that effort will further enhance ourselves at goldman Sachs on is having our already outstanding reputation for a great culture—a culture of teamwork, research and education. So HJd is clearly communication, and camaraderie. i felt on the cutting edge. it’s an organization that the HJd culture was very similar. that has a great past but an unbelievable future. NYU PHYSICIAN: What do you hope to accomplish? NYU PHYSICIAN: What makes HJD special to GARY COHN: i want to help the hospital you? become the premier institution for GARY COHN: the people. dr. Joseph musculoskeletal medicine as well as Zuckerman (surgeon-in-chief of the orthopedics. Like the financial services Hospital for Joint diseases and the Walter industry, the Hospital for Joint diseases is a.L. thompson Professor of orthopaedic trying to adapt to a new world and a new Surgery chair of orthopaedics), dr. Steven way of doing things that didn’t exist years abramson (professor and director of ago.