12th Biennial Meeting Society for Research on Biological Rhythms Program and Abstracts SRBR May 22–26, 2010 Sandestin Golf and Beach Resort Destin, Florida SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS I Executive Committee David Hazlerigg Pat DeCoursey University of Aberdeen University of South Carolina Joseph Takahashi, President University of Texas Southwestern Elizabeth Klerman Jeffrey Hall Medical Center Harvard Medical School Brandeis University Michael Hastings, President-Elect Achim Kramer Woody Hastings MRC Laboratory of Molecular Charité University, Berlin Harvard University Biology Takashi Yoshimura Elizabeth B. Klerman Paul Hardin, Treasurer Nagoya University Brigham and Women’s Hospital, Texas A&M University Harvard Medical School Facilities Chair Rebecca Prosser, Secretary Michael Menaker University of Tennessee Shelley A. Tischkau University of Virginia Southern Illinois University, School Martin Zatz, Editor, Members-at-Large of Medicine Journal of Biological Rhythms Horacio de la Iglesia Committee on Animal Committee on Communications University of Washington Regulations Erik Herzog Frank AJL Scheer, Chair Laura Smale, Chair Washington University Brigham and Women’s Hospital, Michigan State University Harvard Medical School Alena Sumova Eric Bittman Institute of Physiology, Academy of Janis Anderson University of Massachusetts Sciences of the Czech Republic Brigham and Women’s Hospital, Lance Kriegsfeld Harvard Medical School Ex-Officio Members University of California–Berkeley Ralph Mistlberger Martha Gillette, President Lawrence Morin Simon Fraser University University of Illinois at Urbana- Stony Brook Medical Center Shelley A. Tischkau Champaign Southern Illinois University, School Lawrence Morin, Comptroller Bylaws and Incorporation of Medicine Stony Brook Medical Center Committee Committee on Trainee Rae Silver, Comptroller Michael N. Nitabach, Chair Columbia University Yale University Professional Development Day Nicolas Cermakian, Chair Martin Zatz, Editor William J. Schwartz McGill University Journal of Biological Rhythms University of Massachusetts Medical School Paul Bartell Program Committee Martha Gillette Pennsylvania State University Ignacio Provencio, Program Chair University of Illinois at Urbana- Marian Comas University of Virginia Champaign Roswell Park Cancer Institute Ravi Allada David Weaver Stephanie Crowley Northwestern University University of Massachusetts Rush University Medical Center Medical School Deborah Bell-Pedersen Erin Fortier Texas A&M University Martin Zatz, Editor McGill University Journal of Biological Rhythms Fernanda Ceriani Michael Hastings Leloir Institute Foundation, Committee on ChronoHistory MRC Laboratory of Molecular Buenos Aires Biology Anna Wirz-Justice, Chair Carla Green Psychiatric University Clinic–Basel Theresa Lee University of Texas Southwestern University of Michigan Medical Center Jo Arendt University of Surrey Luciano Marpegan Stacey Harmer Washington University University of California–Davis Eric Bittman University of Massachusetts– Ozgur Tataroglu Mary Harrington Amherst University of Heidelberg Smith College Serge Daan Thomas Wallach University of Groningen Charité–Universitätsmedizin, Berlin II SRBR 2010 PROGRAM AND ABSTRACTS Committee on Trainee Research Sato Honma John Hogenesch Awards Hokkaido University School of University of Pennsylvania School Medicine of Medicine Nicolas Cermakian, Chair McGill University William J. Schwartz Helena Illnerova University of Massachusetts Czech Academy of Sciences Michael Antle Medical School University of Calgary Carl Hirschie Johnson Vanderbilt University Simon Archer Editorial Board University of Surrey Serge Daan David Kennaway University of Groningen University of Adelaide Medical Paul Bartell School Penn State University Bruce Goldman University of Connecticut Charalambos P. Kyriacou Stephanie Crowley University of Leicester Rush University Medical Center Terry Page Vanderbilt University Jennifer Loros Patrick Emery Dartmouth Medical School University of Massachusetts Ueli Schibler Medical School University of Geneva Ralph E. Mistlberger Simon Fraser University Kai-Florian Storch Michael Terman McGill University Columbia University Lawrence Morin Stony Brook Medical Center Jeffrey Gimble Advisory Board Pennington Biomedical Research Hitoshi Okamura Center Timothy J. Bartness Kyoto University Georgia State University Namni Goel Till Roenneberg University of Pennsylvania School Domien G.M. Beersma Ludwig Maximilians University University of Groningen of Medicine Rae Silver Stacey Harmer Eric Bittman Columbia University University of Massachusetts– University of California–Davis Laura Smale Amherst Elizabeth Klerman Michigan State University Vincent M. Cassone Brigham and Women’s Hospital, Joseph S. Takahashi University of Kentucky Harvard Medical School University of Texas Southwestern Yi Liu Horacio O. de la Iglesia Medical Center University of Washington University of Texas Southwestern Russell N. Van Gelder Medical Center Marie Dumont University of Washington University of Montréal Rob Lucas David R. Weaver University of Manchester Charmane Eastman University of Massachusetts Valerie Mongrain Rush Medical Center Medical School Hôpital du Sacré-Coeur de Montréal Isaac Edery David K. Welsh Ezio Rosato Rutgers University University of California–San Diego University of Leicester Russell Foster Conference Arrangements Shin Yamazaki University of Oxford Vanderbilt University Jaga Giebultowicz Oregon State University Journal of Biological Rhythms Martha Gillette Office of Continuing Education Martin Zatz, Editor University of Illinois at Urbana- 901 West University Avenue, Champaign Suite 101 Associate Editors Michael Gorman Urbana, IL 61801 Josephine Arendt University of California–San Diego Phone: 217-333-2880 University of Surrey E-mail: [email protected] Carla Green Paul Hardin University of Texas Southwestern Texas A&M University Medical Center Michael Hastings Erik Herzog MRC Laboratory of Molecular Washington University Biology SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS III SRBR Thanks Our Sponsors IV SRBR 2010 PROGRAM AND ABSTRACTS Table of Contents General Information. 3 Headquarters SRBR Information Desk and Message Center Messages Hotel Check-In Posters The Village of Baytowne Wharf Special Events Meeting at a Glance. 5 Trainee Professional Development Day. 7 Program Overview. 11 Poster Titles. 23 Slide Session Abstracts. 36 Poster Abstracts. 76 Index of Authors. .223 Index of Keywords. .234 Participants. .238 Notes. 251 Maps. 259 SOCIETY FOR RESEARCH ON BIOLOGICAL RHYTHMS 1 President’s Welcome The Society for Research on Biological Rhythms was founded in 1986 and 2010 marks the 24th anniversary of SRBR—a special date in circadian numerology! For this year, we look forward to another vibrant meeting continuing our tradition of leading-edge science, camaraderie, and a beautiful venue. We are the beneficiaries of months of planning and work by many people. Program Chair Ignacio Provencio and his committee have put together an outstanding set of scientific sessions, diverse in form and content. Nicolas Cermakian and his committee have organized the SRBR Trainee Professional Development Day and overseen trainee awards for research accomplishment. Frank Scheer and his committee have continued to revitalize the SRBR Web site. Just as important, Michael Nitabach and his committee on SRBR Bylaws and Incorporation have completed the task of revising the Bylaws and have paved the way for the re-incorporation of SRBR. Paul Hardin and Rebecca Prosser have taken on the task of the re-incorporation of SRBR, which is now complete. With the adoption of the revised SRBR Bylaws, the Society begins a new era as a mature entity poised for future growth in the field. We owe a great debt to the efforts of our past presidents, William Schwartz and Martha Gillette, for laying the foundation for the re-incorporation and stabilization of SRBR. Finally, I thank all the members of the Executive Committee who have worked so diligently over the last two years on behalf of the Society. The SRBR Biennial Meeting is an opportunity for convening the Board of Directors, our standing committees on Animal Issues, chaired by Laura Smale; on ChronoHistory, chaired by Anna Wirz-Justice; and on Communications, chaired by Frank Scheer; as well as the Editorial Board of the Journal of Biological Rhythms, chaired by Martin Zatz. Results of the election of the new SRBR board, coordinated by Martha Gillette, chair of the Nominations Committee, will be announced at the Business Meeting on Wednesday. Special thanks are due Michelle Chappell and Michelle Marquart at Conferences & Institutes of the University of Illinois, for their skill in organizing this event and coordinating with Sandestin. We are deeply grateful to our corporate and government sponsors for their generous support.Their names are listed at the front of this program. I extend my thanks to all of you, presenters and participants, for sharing your ideas, energy, opinions, and wisdom to make the meeting such a success. Best wishes for a great meeting! Joseph S. Takahashi, President, SRBR, 2008–2010 2 SRBR 2010 PROGRAM AND ABSTRACTS General Information Headquarters is at the Baytowne Conference Center, which is conveniently located within walking distance of all hotel rooms. SRBR Information Desk and Message Center is in the Foyer of the Baytowne Conference Center main level. The desk hours are as follows: Friday 5/21 2:00–6:00 PM Saturday 5/22 2:00–8:00 PM Sunday 5/23 7:00–11:00