British Society for Parasitology Trypanosomiasis and Leishmaniasis Symposium Advances in Basic and Applied Research Granada, Spain, 8th- 11th March 2020 0 Venue Information Address: Hotel Abades Nevada Palace, Calle Sultana, 3, Granada GR 18008 Tel: +34 902 22 25 70 Taxi: There are 60 designated taxi ranks in Granada. They all have a square blue sign with a T. Taxis can be hailed on the street too. They have a green light on their roof when they are available. You can book a taxi online using one of theses applications: pidetaxi Granada application https://www.granadataxi.com/pidetaxi-app or 1Taxi! application https://radiotaxigenil.com/taxi-online/ There are two taxi companies in Granada: Tele Radio Taxi Granada on 958 28 00 00 and Radio Taxi Genil on 958 13 23 23. You can call them to book a taxi in advance or immediately, if they are available near you 1 British Society for Parasitology Trypanosomiasis and Leishmaniasis Symposium GRANADA 2020, SPAIN Sunday, 8 to Wednesday, 11 March 2020 Advances in Basic and Applied Research Dear Colleagues, Nowadays many scientific meetings have grown very large and perhaps include too many broad fields and are rather impersonal and hard to navigate. The focused symposium in Granada and kindly provided by the British Society for Parasitology is centred on a small group of neglected diseases caused by related protozoa parasites and offers the perfect venue to meet together and with a suitable number of scientists to make the most of our time together. Furthermore, we chose a hotel as the symposium venue to increase considerably the potential for meeting, exchanging ideas and collaborating. We hope the cultural backdrop of the city of Granada will enrich the scientific framework and the exchange and knowledge of the conference attendees in the late afternoon, after poster parties and at the Gala dinner in a restaurant located on the Alhambra hillside, overlooking the Albaicin old city centre. The eight sessions included in the congress cover many of the major aspects of current research activity and all talks will be presented in the same auditorium in one concurrent session, avoiding the need to choose between talks. At the end of the auditorium room we have also located the poster panels towards the patio were coffee breaks take place to further encourage interactions. We anticipate that the meeting will facilitate a highly enjoyable and productive occasion, allowing delegates to present the most relevant advances of the year in the molecular and cellular biology of the kinetoplastids. This framework has also been designed to facilitate the participation and presentation of work by young researchers as well as established investigators. The BSP2020 Granada Symposium Committee will recognize best presentations and posters with awards to young researchers. In addition, a prominent member of the BSP will receive a whole career award in the opening plenary session of the Congress. We sincerely hope that you are inspired by this meeting and will enjoy the cordiality of the ancient and beautiful city of Granada, forge new scientific friendships while learning and exchanging your latest findings, ideas and questions. I will close by thanking the British Society for Parasitology for allowing this great opportunity to exchange our research in Granada into this, sometimes forgotten, area of parasitology and neglected diseases. Miguel Navarro PhD. Professor of Research at the CSIC. Spanish National Council for Research Local Organisers Domingo Rojas; Diana Lopez-Farfan and Miguel Navarro with special thanks to Rosa Cruz for facilitating the meeting. 2 Contents VENUE INFORMATION ................................................................................................ 1 Local Organisers ................................................................................................................................ 2 About Granada (Local Information) .................................................................................................... 4 About Presentations ............................................................................................................................ 4 Information for Oral Presentations ..................................................................................................... 4 Information for Poster Presentations .................................................................................................. 4 General Meeting Information .............................................................................................................. 5 Reception and Registration ................................................................................................................ 5 House keeping ................................................................................................................................... 5 Internet Access .................................................................................................................................. 5 About the British Society for Parasitology ........................................................................................ 5 About .................................................................................................................................................. 5 Membership ....................................................................................................................................... 6 The BSP Council 2020 ....................................................................................................................... 6 TIMETABLE AT A GLANCE ..................................................................................... 7 FULL PROGRAMME ............................................................................................... 11 Day 1 Talks ......................................................................................................................................... 11 Opening Plenary - at 19:00 to 20:00 ................................................................................................ 11 Day 2 Talks ......................................................................................................................................... 12 Host-Parasite Interactions - at 09:00 to 11:10 .................................................................................. 12 Genomics, Evolution and Gene Expression -at 11:40 to 13:30 ....................................................... 15 Gene Expression of Surface Protiens -at 15:00 to 17:30 ................................................................. 17 Poster Session A with Refreshments - at 17:30 to 19:30 ................................................................. 21 Conference Dinner - at 18:30 till late ................................................................................................ 21 Day 3 Talks ......................................................................................................................................... 22 Parasite Cell Biology - at 09:00 to 11:10 .......................................................................................... 22 Parasite Molecular and Cell Biology -at 11:30 to 14:00 ................................................................... 25 Immunology and Cell Biology -at 15:00 to 17:30 ............................................................................. 29 Poster Session B with Refreshments - at 17:30 to 19:30 ................................................................. 33 Day 4 Talk ........................................................................................................................................... 34 Biochemistry and Gene Expression -at 09:00 to 10:50 .................................................................... 34 Novel Drug Therapies and New Targets -at 11:20 to 13:20 ............................................................. 36 Closing Plenary at 13:10 to 13:55 .................................................................................................... 39 Closing Remarks at 13:00 to 13:15 .................................................................................................. 39 Poster Presentations ......................................................................................................................... 40 INDEX ...................................................................................................................... 95 CITY METRO MAP ............................................................................................... 102 3 About Granada (Local Information) Just a few years ago, in 2014, the Millennial of the founding of the first Kingdom of Granada, the Zirí, the predecessor of the Nasrid Kingdom, which led Granada to reach highest levels of cultural splendour, was celebrated. Since the beginning of its existence, the Kingdom of Granada has been a melting pot of cultures having collected and given the world important sages and writers. Throughout these thousand years, Granada has formed an attractive city structure with unique historical monuments such as the Alhambra or its unique cathedral and monastery of La Cartuja. Today Granada is a modern, open city with a large University and several research Institutes of the Spanish National Research Council (CSIC) and the Andalusian Board of recognized prestige. An example of this is the Health Sciences Park where it focuses on the area of biomedicine, teaching, research, business and