JOURNAL OF VIROLOGY VOLUME 62 * SEPTEMBER 1988 * NUMBER 9 Arnold J. Levine, Editor in Chief Thomas E. Shenk, Editor (1989) (1989) Princeton University Princeton University Princeton, N.J. Princeton, N.J. Michael B. A. Oldstone, Editor (1993) Anna Marie Skalka, Editor (1989) Bernard N. Fields, Editor (1993) Scripps Clinic & Research Fox Chase Cancer Center Harvard Medical School Foundation Philadelphia, Pa. Boston, Mass. La Jolla, Calif. George F. Vande Woude, Editor (1992) Robert A. Lamb Editor (1992) NCI-Frederick Cancer Research Facility Northwestern University Frederick Md. Evanston, Ill. EDITORIAL BOARD James Alwine (1988) Mary-Jane Gething (1990) Malcolm Martin (1989) Norman P. Salzman (1990) David Baltimore (1990) Joseph C. Glorioso (1989) Robert Martin (1990) Joseph Sambrook (1988) Amiya K. Banerjee (1990) Stephen P. Goff (1988) Warren Masker (1990) Charles E. Samuel (1989) Tamar Ben-Porat (1990) Larry M. Gold (1988) James McDougall (1990) Priscilla A. Schaffer (1990) Kenneth I. Berns (1988) Hidesaburo Hanafusa (1989) Thomas Merigan (1989) Sondra Schlesinger (1989) Michael Botchan (1989) John Hassell (1989) Lois K. Miller (1988) Manfred Schubert (1988) Thomas J. Braciale (1988) William S. Hayward (1990) Peter Model (1989) Bart Sefton (1988) Joan Brugge (1988) Ari H. Helenius (1990) Bernard Moss (1989) Bert L. Semler (1989) Michael J. Buchmeier (1989) Roger Hendrix (1990) Opendra Narayan (1988) Charles J. Sherr (1990) Barrie J. Carter (1990) John J. Holland (1990) Joseph R. Nevins (1988) Saul J. Silverstein (1988) Sherwood Casjens (1990) Nancy Hopkins (1989) Erling Norrby (1989) Patricia G. Spear (1990) John M. Coffin (1989) Alice S. Huang (1990) Nancy G. Nossal (1990) Bruce Stillman (1988) Charles N. Cole (1989) Steve Hughes (1988) Dennis O'Callaghan (1989) Mark F. Stinski (1989) Neal Copeland (1989) Eric Hunter (1990) Joseph Pagano (1990) James Strauss (1990) Donald Court (1990) Tony Hunter (1989) Takis Papas (1990) F. William Studier (1990) Richard Courtney (1989) Richard Hyman (1989) J. Thomas Parsons (1989) Lawrence S. Sturman (1988) Clyde S. Crumpacker II Nancy Jenkins (1989) Ulf G. Pettersson (1989) Bill Sugden (1990) (1988) Richard A. Katz (1990) Lennart Philipson (1990) John M. Taylor (1990) Bryan R. Cullen (1990) Jack D. Keene (1988) Lewis I. Pizer (1990) Howard M. Temin (1988) Thomas Curran (1988) Thomas J. Kelly, Jr. (1988) Carol Prives (1989) Inder Verma (1989) Walter Doerfler (1989) Eli Keshet (1990) Vincent Racaniello (1990) Volker M. Vogt (1990) Elvera Ehrenfeld (1989) Elliott Kieff (1990) R. Frank Ramig (1988) Edward K. Wagner (1989) Robert N. Eisenman (1988) David Knipe (1988) Fred Rapp (1990) Raymond M. Welsh, Jr. (1988) Suzanne U. Emerson (1989) Daniel Kolakofsky (1989) Dan S. Ray (1989) Gail Wertz (1988) Mary K. Estes (1989) Hsing-Jien Kung (1990) Solon L. Rhode (1989) Reed B. Wickner (1988) Ellen Fanning (1988) Ching-Juh Lai (1990) Harriet Robinson (1988) Eckard Wimmer (1988) Emanuel A. Faust (1990) Michael Lai (1988) William S. Robinson (1989) Owen Witte (1989) S. Jane Flint (1990) Robert A. Lazzarini (1990) Bernard Roizman (1988) Charles Hamish Young (1989) Donald Ganem (1988) Myron Levine (1988) John K. Rose (1988) Harald zur Hausen (1989) Costa Georgopolous (1989) Maxine Linial (1988) Naomi Rosenberg (1989) Walter Gerhard (1989) Douglas R. Lowy (1989) Roland R. Rueckert (1988) Helen R. Whiteley, Chairman, Publications Board Kirk Jensen, Director of Publications Linda M. Illig, Managing Editor, Journals Judith Nedrow, Production Editor The Journal of Virology (ISSN 0022-538X), a publication of the American Society for Microbiology, 1913 I St., N.W., Washington, DC 20006, is devoted to the dissemination offundamental knowledge concerning viruses of bacteria, plants, and animals. Investigators are invited to submit reports of original research in all areas of basic virology, including biochemistry, biophysics, genetics, immunology, morphology, physiology, and pathogenesis and immunity. Instructions to authors are published in the January issue each year; reprints are available from the editors and the Publications Department. The Journal is issued monthly, one volume per year. The nonmember subscription price is $350 per year; single copies are $30. The member subscription price is $41 (foreign, $63 [air drop shipping]) per year; single copies are $8.00. Correspondence relating to subscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submitted manuscripts, and general editorial matters should be directed to the ASM Publications Department, 1913 I St., N.W., Washington, DC 20006 (phone: 202 833-9680). 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This consent is given on the condition, however, that the copier pay the stated per-copy fee through the Copyright Clearance Center, 21 Congress St., Salem, MA 01970, for copying beyond that permitted by Sections 107 and 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works, or for resale. Author Index Ahmed, Rafi, 3301 Geballe, Adam P., 3334 Li, Ruo-ping, 3233 Sato, Hiroshi, 3288 Alwine, James C., 3182 Geiduschek, E. Peter, 3455 Satoh, Shuichi, 3517 Anderson, Garth R., 3540 Glorioso, Joseph C., 3274 Mackow, Erich R., 3509 Sayre, Michael H., 3455 Ansorge, Wilhelm, 3341 Gompels, Ursula A., 3250 Manly, Kenneth F., 3540 Schickedanz, Jorg, 3341 Goodall, Jonathan, 3527 Manuelidis, Elias E., 3103 Scraba, Douglas G., 3474 Baglia, Laurel A., 3415 Gouilloud, Evelyne, 3328 Manuelidis, Laura, 3103 Sen, Ganes C., 3175 Barbosa, Miguel S., 3242 Greenberg, Harry B., 3509 Markowitz, Rhea-Beth, 3388 Senkowski, Andrea, 3527 Baumbach, William R., 3151 Guetta, E., 3438 Matloubian, Mehrdad, 3301 Shaw, George M., 3501 Bello, Leonard J., 3319 Guillon, Jean-Claude, 3484 Matsuda, Keizaburoh, 3517 Shaw, James E., 3415 Berman, Phillip W., 3135 McGuire, Travis C., 3488 Shaw, Robert D., 3509 Biempica, Luis, 3422 Haffar, Omar K., 3135 Melief, C. J. M., 3156 Shepard, Alyssa, 3364 Blais, Bruce P., 3431 Hahn, Beatrice H., 3501 Mdric, Claude, 3328 Simon, Richard S., 3301 Bockman, Jeffrey M., 3120 Harty, John T., 3210 Miller, Lois K., 3109 Smith, Frances I., 3084 Britt, William J., 3309 Hayami, Masanori, 3506 Minson, Anthony C., 3274 Snyder, Robert, 3422 Brown, David W., 3431 Hemstrom, Catharina, 3258 Mocarski, Edward S., 3334 Southern, Peter J., 3301 Byrn, Randal A., 3274 Henner, Dennis J., 3193 Monroe, James E., 3497 Spahr, Pierre-Frangois, 3328 Byrne, Janet C., 3143 Henry, Catherine, 3233 Morgan, William C., 3407 Spalholz, Barbara A., 3143 Herr, Winship, 3364 Morrow, Casey D., 3501 Spector, Deborah H., 3463 Calender, Alain, 3497 Hilgers, Jo, 3506 Muggeridge, Martin I., 3274 Spegelaere, P., 3438 Carter, Barrie J., 3356 Hintz, Ray, 3422 Mulder, Carel, 3497 Spivack, Jordan G., 3281, Celis, Esteban, 3128 Hodges, Robert S., 3474 Murdoch, Geoffrey, 3103 3493 Cheevers, William P., 3488 Holmes, Ian H., 3509 Spruyt, N., 3438 Chisholm, George E., 3193 Honess, Robert W., 3250 Nicholas, John, 3250 Staprans, Silvija I., 3463 Choubey, Divaker, 3175 Hood, Leroy E., 3501 Nordqvist, Katarina, 3258 Stehelin, Dominique, 3233 Claessens, Johnny A. J., 3092 Hovanessian, Ara G., 3077 Norton, Linda K., 3488 Steiner, Israel, 3493 Clarke, Jennifer, 3364 Hovi, Tapani, 3536 Nunes, Wylla M., 3135 Stephens, Edward B., 3309 Cohen, Gary H., 3274 Howley, Peter M., 3143 Stillman, Bruce, 3445 Cole, Michael D., 3151 O'Boyle, Donald R., II, 3493 Daniel 3540 Ohara, Yoshiro, 3527 Stoler, L., Colston, Elizabeth M., 3151 Isola, Vicki J., 3274 Strynadka, Natalie C. J., 3474 Cornelis, J. J., 3438 Ohori, Hitoshi, 3517 Su, Chun Yeh, 3422 Cotmore, S. F., 3438 Oleszak, Emilia L., 3103 Jameson, Bradford A., 3501 Subramani, Suresh, 3378 Craxton, Molly A., 3250 O'Reilly, David R., 3109 Summers, J., 3513 Crumpacker, Clyde S., 3224 J0rgensen, Eva C., 3217 Oroszlan, Stephen, 3167 J0rgensen, Poul, 3217 O'Rourke, Katherine I., 3488 Dabrowski, Christine, 3182 Ou, Dawei, 3128 Tal, J., 3438 Dales, S., 3371 Kano-Sueoka, Tamiko, 3201 Tong, Jennifer, 3265 Darawshi, T., 3438 Kaplan, David R., 3407 Pagano, Joseph S., 3288 Toth, Marcia, 3527 Debuire, Brigitte, 3233 Kappes, John C., 3501 Palese, Peter, 3084, 3348 Trempe, James P., 3356 de Goede, R. E. Y., 3156 Kasher, Mary S., 3295 Pallas, David C., 3407 Tsai, Wen-Po, 3167 Denton, Amy, 3445 Kent, Stephen B. H., 3501 Parker, J. M. Robert, 3474 Tucker, Thomas J., 3274 Derse, David, 3522 King, David M., 3201 Pedersen, Finn S., 3217 Deyerle, Karen L., 3378 Kingsbury, David T., 3120 Pepperkok, Rainer, 3341 Dietzschold, Bernhard, 3128 Kjeldgaard, Niels O., 3217 Pettersson, Ulf, 3258