PRODUCT DATA SHEET Bioworld Technology,Inc. GNL3 polyclonal antibody Catalog: BS8233 Host: Rabbit Reactivity: Human BackGround: Applications: Nucleostemin, also designated Nucleolar GTP-binding WB 1:500 - 1:2000 protein 3, is a member of the MMR1/HSR1 GTP-binding IF 1:10 - 1:100 protein family. It is expressed in the nucleoli of adult IP 1:50 - 1:100 CNS stem cells, primitive bone marrow cells, embryonic Storage&Stability: stem cells and in several cancer cell lines. Nucleostemin Store at 4°C short term. Aliquot and store at -20°C long is often used as a stem cell marker. Overexpression or de- term. Avoid freeze-thaw cycles. pletion of the protein can reduce cell proliferation in CNS Specificity: stem cells. Nucleostemin shuttles between the nucleus GNL3 polyclonal antibody detects endogenous levels of and the nucleolus and may be important in maintaining GNL3 protein. the proliferative capacity of stem cells. Nucleostemin is DATA: important in the growth regulation of liver cancer, gastric cancer and several other cancer types. The gene encoding Nucleostemin is localized to chromosome 3p21.1. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Molecular Weight: ~ 62 kDa WesternBlot (WB) analysis of GNL3 polyclonal antibody Swiss-Prot: Note: Q9BVP2 For research use only, not for use in diagnostic procedure. Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific im- munogen and the purity is > 95% (by SDS-PAGE). Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add： 1660 South Highway 100, Suite 500 St. Louis Park, Add： No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151 .