BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance Supplemental material placed on this supplemental material which has been supplied by the author(s) Thorax Supplement RAND appropriateness panel to determine the applicability of UK guidelines on the management of acute respiratory distress syndrome (ARDS) and other strategies in the context of the COVID-19 pandemic ǂ*Mark JD Griffiths FRCP1,2,3, *Susanna Meade MB ChB 4, *Charlotte Summers PhD5, *Danny F McAuley MD6, *Alastair G Proudfoot FRCP1,3,8, Marta Montero Baladia9, Paul Dark PhD10, Kate Diomede MB ChB11 Simon J. Finney FRCA1,3, Lui G Forni PhD12, Christopher Meadows FRCP 4, Ian A Naldrett MSc13,14, Brijesh V. Patel FFICM14,15 Gavin D. Perkins MD16, Mark A Samaan MB BS4, Laurence Sharifi FRCA9, Ganesh Suntharalingam FRCA17,18, Nicholas T Tarmey FFICM19, Matt P Wise DPhil20, Harriet F Young MRCP1, Peter M Irving MD4,7 1 Barts Heart Centre, St Bartholomew’s Hospital, London, UK. 2 National Heart & Lung Institute, Imperial College London, London, UK. 3 William Harvey Research Institute, Queen Mary University of London, London, UK. 4 Guy’s and St Thomas’ NHS Foundation Trust, London, UK. 5 Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, UK. 6 Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Science, Queen’s University Belfast and Regional Intensive Care Unit, Royal Victoria Hospital, Belfast UK. 7 School of Immunology and Microbial Sciences, King's College London, UK. 8 Nightingale Hospital, London, UK. 9 Barts & The London School of Anaesthesia, The Royal London Hospital, Whitechapel, London, E1 1BB, UK. 10 Division of Infection, Immunity and Respiratory Medicine, Manchester NIHR Biomedical Research Centre, University of Manchester, UK. 11 East Kent Hospitals NHS Foundation Trust, UK. 12 Department of Clinical & Experimental Medicine, Faculty of Health Sciences, University of Surrey & Intensive Care Unit, Royal Surrey Foundation Trust, Guildford, Surrey, UK. 13 College of Nursing, Midwifery and healthcare, University of West London, UK. 14 Adult Critical Care Units, Royal Brompton & Harefield NHS Foundation Trust, UK. Griffiths M, et al. Thorax 2021;0:1–7. doi: 10.1136/thoraxjnl-2021-216904 BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance Supplemental material placed on this supplemental material which has been supplied by the author(s) Thorax 15 Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London, UK. 16 Warwick Clinical Trials Unit, University of Warwick, Coventry, UK. 17 Intensive Care Society, London, UK. 18 London North West University Healthcare NHST, London, UK. 19 Academic Department of Critical Care, Portsmouth Hospitals University NHS Trust, UK. 20 University Hospital of Wales, Cardiff, CF14 4XW, UK. *These authors have contributed equally ǂ Corresponding author: Mark Griffiths Barts Heart Centre King George V Building St Bartholomew’s Hospital West Smithfield London EC1A 7BE Mobile: 07875 999126 Barts: 0203 765 8054 Email: [email protected] Griffiths M, et al. 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