Scientific Activities 2002 Rehovot, Israel Edited, Designed and Typeset by Aviva Ovadia Cover Design by Shoshana Zioni, Graphics Department We wish to thank all the secretarial staff who worked on this project, without whose help this publication would not be possible. Printed in Israel By Publishing Department Weizmann Institute of Science ISSN 0083-7849 Contents Board of Governors vii Scientific and Academic Advisory Committee xv Officers of the Weizmann Institute xvii Weizmann Institute of Science xix Faculty of Biochemistry Faculty of Biochemistry - Overview 3 Biological Chemistry 5 Molecular Genetics 13 Plant Sciences 21 Biological Services 27 Avron-Wilstätter Minerva Center for Research in Photosynthesis 29 Y. Leon Benoziyo Institute for Molecular Medicine 31 Dr. Josef Cohn Minerva Center for Biomembrane Research 33 Crown Human Genome Center 35 Mel Dobrin Center for Nutrition 37 Leo and Julia Forchheimer Center for Molecular Genetics 39 Kekst Family Center for Medical Genetics 41 Charles W. and Tillie K. Lubin Center for Plant Biotechnology 43 M.D. Moross Institute for Cancer Research 45 David and Fela Shapell Family Center for Genetic Disorders Research 47 Harry and Jeannette Weinberg Center for Plant Molecular Genetics Research 49 Faculty of Biology Faculty of Biology - Overview 53 Biological Regulation 55 Immunology 61 Molecular Cell Biology 69 Neurobiology 83 Veterinary Resources 89 Helen and Norman Asher Center for Human Brain Imaging 91 Nella and Leon Benoziyo Center for Neurosciences 93 Carl and Micaela Einhorn-Dominic Institute for Brain Research 95 Murray H. and Meyer Grodetsky Center for Research of Higher Brain Functions 97 Robert Koch-Minerva Center for Research in Autoimmune Diseases 99 Belle S. and Irving E. Meller Center for the Biology of Aging 101 Gabrielle Rich Center for Transplantation Biology Research 103 Willner Family Center for Vascular Biology 105 iii iv Women's Health Research Center 109 Yad Abraham Research Center for Cancer Diagnostics and Therapy 111 Faculty of Chemistry Faculty of Chemistry - Overview 115 Chemical Physics 119 Environmental Sciences and Energy Research 125 Materials and Interfaces 129 Organic Chemistry 135 Structural Biology 141 Solar Research Facilities Unit 145 Chemical Services 147 Center for Energy Research 155 Fritz Haber Center for Physical Chemistry 157 Ilse Katz Institute for Material Sciences and Magnetic Resonance Research 159 Helen and Martin Kimmel Center for Archaeological Science 161 Helen and Martin Kimmel Center for Molecular Design 163 Helen and Milton A. Kimmelman Center for Biomolecular Structure and Assembly 165 Joseph and Ceil Mazer Center for Structural Biology 167 Gerhard M.J. Schmidt Minerva Center for Supramolecular Architecture 169 Sussman Family Center for the Study of Environmental Sciences 171 Faculty of Physics Faculty of Physics - Overview 175 Condensed Matter Physics 177 Particle Physics 183 Physics of Complex Systems 191 Physics Services 199 Nella and Leon Benoziyo Center for High Energy Physics 201 Joseph H. and Belle R. Braun Center for Submicron Research 203 Albert Einstein Minerva Center for Theoretical Physics 207 Maurice and Gabriella Goldschleger Center for Nanophysics 209 Minerva Center for Nonlinear Physics of Complex Systems 211 Faculty of Mathematics and Computer Science Faculty of Mathematics and Computer Science - Overview 217 Computer Science and Applied Mathematics 219 Mathematics 225 Arthur and Rochelle Belfer Institute of Mathematics and Computer Science 231 Carl F. Gauss Minerva Center for Scientific Computation 233 Minerva Center for Formal Verification of Reactive Systems 235 v Feinberg Graduate School Feinberg Graduate School 241 Science Teaching 295 Young@Science 303 Aharon Katzir-Katchalski Center 305 Institute-Wide Centers Clore Center for Biological Physics 311 Dolfi and Lola Ebner Center for Biomedical Research 313 Academic Secretariat 315 Conference Section 347 Division of Information Systems 351 Division of Logistics and Research Services 361 Amos de-Shalit Foundation 365 Davidson Institute for Science Education 367 Yeda Research and Development Company Ltd. 369 Current Research Activities on the Internet 371 Scientific Activities on the Internet 373 The Board of Governors Gershon Kekst*, New York, NY, USA, Chair of the Board (until November 2002) Stuart E. Eizenstat**, Washington, DC, USA, Chair of the Board (from November 2002) H. Thomas Beck*, Toronto, Ont, Canada, Deputy Chair of the Board Lawrence S. Blumberg*, New York, NY, USA, Deputy Chair of the Board Robert J. Drake*, Wassenaar, The Netherlands, Deputy Chair of the Board (from November 2002) Dame Vivien Duffield*, Geneva, Switzerland, Deputy Chair of the Board Prof. Michael Sela*, Weizmann Institute, Rehovot, Israel, Deputy Chair of the Board S. Donald Sussman*, Greenwich, CT, USA, Deputy Chair of the Board Joshua Maor*, Ramat-Gan, Israel, Chair of the Executive Council (until November 2002) Abraham Ben-Naftali*, Tel Aviv, Israel, Chair of the Executive Council (from November 2002) Oded Aboodi, New York, NY, USA (from November 2002) Ayala Zacks Abramov, Jerusalem, Israel Gary M. Abramson, N. Bethesda, MD, USA Sem Almaleh, Geneva, Switzerland Prof. Ruth Arnon*, Weizmann Institute, Rehovot, Israel Prof. Zvi Artstein**, Weizmann Institute, Rehovot, Israel Helen S. Asher, Chicago, IL, USA Robert H. Asher*, Chicago, IL, USA, ex-officio member (also elected member) David Assia, Or-Yehuda, Israel Yehuda Assia*, Tel Aviv, Israel Prof. John M. Ball, University of Oxford, Oxford, UK Prof. David Baltimore, Caltech, Pasadena, CA, USA Prof. Allen J. Bard, University of Texas, Austin, TX, USA Hanan Bar-On, Weizmann Institute, Rehovot, Israel (from November 2002) Robert G. Begam**, Phoenix, AZ, USA Robert Belfer, New York, NY, USA Prof. Haim Ben-Shahar, Tel Aviv, Israel Dr. Emile Benassayag, Paris, France Marshall Bennett, Chicago, IL, USA *Member of the Executive Council **Member of the Executive Council from November 2002 vii viii Prof. Sir Michael V. Berry, University of Bristol, Bristol, UK Maks L. Birnbach*, New York, NY, USA René Braginsky, Zurich, Switzerland (from November 2002) Frances Brody, Los Angeles, CA, USA Andrea M. Bronfman, New York, NY, USA (until August 19, 2002) L. Yehuda Bronicki*, Yavne, Israel Stanley Chais*, Beverly Hills, CA, USA Prof. Ilan Chet*, President, Weizmann Institute, Rehovot, Israel Joseph Ciechanover, Tel Aviv, Israel Doron Cohen*, Ramat-Gan, Israel Prof. Marvin L. Cohen, University of California, Berkeley, CA, USA (from November 2002) Norman D. Cohen*, New York, NY, USA Sir Ronald Cohen, London, UK Prof. Mildred Cohn, University of Pennsylvania, Philadelphia, PA, USA Samy Cohn*, Rio de Janeiro, RJ, Brazil Lester Crown*, Chicago, IL, USA Prof. Paul J. Crutzen, Max-Planck-Institut für Chemie, Mainz, Germany Dr. Hubert Curien, Paris, France Prof. Constantine M. Dafermos, Brown University, Providence, RI, USA Leslie L. Dan, Scarborough, Ont, Canada The Hon. Mrs. Janet de Botton, London, UK Raoul de Picciotto, Monte-Carlo, Monaco Meir de Shalit, Herzliya Pituach, Israel Helen Diller, Woodside, CA, USA Prof. Charles A. Dinarello, University of Colorado, Denver, CO, USA Dr. Zvi Dinstein, Tel Aviv, Israel Ido Dissentshik*, Tel Aviv, Israel Sonnie Dockser, Bethesda, MD, USA Prof. Israel Dostrovsky*, Weizmann Institute, Rehovot, Israel Prof. Sidney D. Drell, SLAC, Menlo Park, CA, USA Prof. Mildred S. Dresselhaus, M.I.T., Cambridge, MA, USA Prof. Aryeh Dvoretzky*, Weizmann Institute, Rehovot, Israel Ralph S. Dweck, Washington, DC, USA Maurice M. Dwek*, Geneva, Switzerland Prof. Michael Eisenbach*, Weizmann Institute, Rehovot, Israel, ex-officio member (until September 2002) Robert Equey, Chene-Bougeries, Switzerland Michael Federmann*, Tel Aviv, Israel Prof. Mitchell J. Feigenbaum, The Rockefeller University, New York, NY, USA Prof. Sir Alan R. Fersht*, FRS, Cambridge University Chemical Laboratory, Cambridge, UK *Member of the Executive Council ix Alan A. Fischer*, Larchmont, NY, USA Prof. Edmond H. Fischer, University of Washington, Seattle, WA, USA Prof. Michael E. Fisher, University of Maryland, College Park, MD, USA Michael R. Forman, Los Angeles, CA, USA William Frankel, Philadelphia, PA, USA Louise Gartner, Dallas, TX, USA Moshe Gavish*, Tel Aviv, Israel Dr. Martin L. Gecht, Chicago, IL, USA Mauricio Gerson, Mexico, D.F., Mexico Martin S. Gerstel*, Jerusalem, Israel Henny Gestetner, OBE, London, UK David Ginsburg*, Washington, DC, USA Françoise Glasberg, Paris, France Prof. Michel E. Goldberg, Institut Pasteur, Paris, France (from November 2002) Prof. Patricia S. Goldman-Rakic, Yale University, New Haven, CT, USA Bram Goldsmith, Beverly Hills, CA, USA Abraham M. Goldwasser*, Savyon, Israel Richard F. Goodman, New York, NY, Israel (until November 2002) Prof. Michael B. Green, University of Cambridge, Cambridge, UK Prof. Yoram Groner*, Weizmann Institute, Rehovot, Israel Prof. François Gros*, Academy of Sciences, Paris, France Joseph Gurwin, New York, NY, USA Wilhelm Haas, Bonn, Germany Joseph D. Hackmey*, Tel Aviv, Israel Gideon J. Hamburger*, Ramat-Gan, Israel Prof. Haim Harari*, Weizmann Institute, Rehovot, Israel Shimshon Harel, Herzliya Pituach, Israel Irving B. Harris, Chicago, IL, USA Lilian Hertzberg, New York, NY, USA Prof. Michael J. Higatsberger, University of Vienna, Vienna, Austria Josef D. Hollander, Herzliya Pituach, Israel Ephraim Ilin*, Tel Aviv, Israel Armando Jinich, Mexico, D.F., Mexico Dr. Yair Kadishay*, Ramat Hasharon, Israel Roberto Kaminitz, Sao Paulo, SP, Brazil Prof. Richard M. Karp, University of California,