Supplementary Table 1 List of modulated transcripts following miR-129-5p overexpression in TPC-1 cells. ID Symbol Genbank ID AveExpr log_FC adj.P.Val Target Scan Description 92585 EMP1 2012 12.15 -3.71 1.06E-04 X Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. Homo sapiens vacuolar protein sorting 26 homolog A (S. pombe) (VPS26A), 10111 VPS26A 9559 11.92 -2.27 1.70E-04 X transcript variant 2, mRNA. 186912 KRT80 144501 11.97 2.62 1.70E-04 Homo sapiens keratin 80 (KRT80), transcript variant 2, mRNA. 92202 LBR 3930 11.86 -1.75 1.70E-04 X Homo sapiens lamin B receptor (LBR), transcript variant 1, mRNA. 33816 KRT34 3885 7.87 1.62 2.48E-04 Homo sapiens keratin 34 (KRT34), mRNA. 121520 CCNA1 8900 9.50 -1.80 2.48E-04 Homo sapiens cyclin A1 (CCNA1), transcript variant 4, mRNA. 211 DPY19L1 23333 10.32 -1.78 2.48E-04 X Homo sapiens mRNA for KIAA0877 protein, partial cds. 15854 CKAP4 10970 13.04 -1.36 2.66E-04 X Homo sapiens cytoskeleton-associated protein 4 (CKAP4), mRNA. 63392 RBM24 221662 10.83 2.39 3.09E-04 Homo sapiens RNA binding motif protein 24 (RBM24), transcript variant 2, mRNA. Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- 36665 GALNT1 2589 9.61 -1.52 3.09E-04 X acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1), mRNA. 18614 C12orf24 29902 10.57 1.76 5.02E-04 Homo sapiens chromosome 12 open reading frame 24 (C12orf24), mRNA. 126848 MCAM 4162 8.72 2.05 5.02E-04 X Homo sapiens melanoma cell adhesion molecule (MCAM), mRNA. 178839 AK2 204 10.31 -1.40 5.02E-04 X Homo sapiens adenylate kinase 2 (AK2), transcript variant AK2C, mRNA. Homo sapiens SH3-domain kinase binding protein 1 (SH3KBP1), transcript variant 43169 SH3KBP1 30011 11.06 -1.32 5.02E-04 X 1, mRNA. 79008 CDK6 1021 9.77 -2.20 6.60E-04 X Homo sapiens cyclin-dependent kinase 6 (CDK6), mRNA. 19367 CACYBP 27101 10.36 -1.61 6.60E-04 X Homo sapiens calcyclin binding protein (CACYBP), transcript variant 2, mRNA. Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 1 90456 ABCB1 5243 8.61 1.19 6.60E-04 X (ABCB1), mRNA. Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 2 118962 KCNJ2 3759 9.21 -1.86 1.18E-03 (KCNJ2), mRNA. 10643 GFRA1 2674 9.87 1.80 1.30E-03 Homo sapiens GDNF family receptor alpha 1 (GFRA1), transcript variant 2, mRNA. 93689 KRT81 3887 14.31 2.03 1.32E-03 Homo sapiens keratin 81 (KRT81), mRNA. Homo sapiens potassium channel tetramerisation domain containing 1 (KCTD1), 157648 KCTD1 284252 8.91 -0.98 1.34E-03 X transcript variant 2, mRNA. Homo sapiens pirin (iron-binding nuclear protein) (PIR), transcript variant 1, 100148 PIR 8544 10.61 -1.21 1.34E-03 mRNA. 183103 LOC375681 0 9.54 1.08 1.34E-03 Homo sapiens LOC375681 (LOC375681), mRNA. Homo sapiens cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 57444 CDKN2C 1031 11.28 -1.19 1.34E-03 (CDKN2C), transcript variant 2, mRNA. Homo sapiens Ras association (RalGDS/AF-6) domain family 5 (RASSF5), 46203 RASSF5 83593 9.43 -1.22 1.34E-03 X transcript variant 4, mRNA. 77345 MORN4 118812 8.45 1.24 1.34E-03 Homo sapiens MORN repeat containing 4 (MORN4), transcript variant 2, mRNA. 27649 DTL 51514 10.14 -1.65 1.34E-03 X Homo sapiens denticleless homolog (Drosophila) (DTL), mRNA. 13581 NPEPPS 9520 11.71 -2.55 1.34E-03 X Homo sapiens aminopeptidase puromycin sensitive (NPEPPS), mRNA. Homo sapiens RAB34, member RAS oncogene family (RAB34), transcript variant 46380 RAB34 83871 11.52 -0.97 1.34E-03 1, mRNA. 42538 ULBP2 80328 10.44 1.50 1.34E-03 Homo sapiens UL16 binding protein 2 (ULBP2), mRNA. 162188 KLHL24 54800 9.29 -1.68 1.34E-03 X Homo sapiens cDNA FLJ14208 fis, clone NT2RP3003264. Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), 84751 CDKN1C 1028 8.77 -1.25 1.34E-03 X transcript variant 1, mRNA. Homo sapiens G protein-coupled receptor, family C, group 5, member C (GPRC5C), 102782 GPRC5C 55890 11.35 -1.04 1.49E-03 transcript variant 2, mRNA. 187003 NF2 4771 13.14 1.46 1.49E-03 Homo sapiens neurofibromin 2 (merlin) (NF2), transcript variant 6, mRNA. 54971 LOC152217 152217 11.89 1.28 1.49E-03 Homo sapiens hypothetical protein BC007882 (LOC152217), mRNA. Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript 12573 HSD11B1 3290 7.77 -0.89 1.49E-03 variant 2, mRNA. Homo sapiens ankyrin repeat domain 10, mRNA (cDNA clone IMAGE:5752308), 82898 ANKRD10 55608 11.02 1.03 1.51E-03 complete cds. 81193 KRTAP2-1 81872 8.72 2.24 1.57E-03 Homo sapiens cDNA clone IMAGE:4472166, with apparent retained intron. 36649 ATP10D 57205 11.13 0.99 1.57E-03 Homo sapiens ATPase, class V, type 10D (ATP10D), mRNA. 42539 ULBP2 80328 9.85 1.40 1.73E-03 Homo sapiens UL16 binding protein 2 (ULBP2), mRNA. Homo sapiens phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange 33693 PREX1 57580 9.42 -1.21 1.70E-03 factor 1 (PREX1), mRNA. Homo sapiens cell division cycle 25 homolog B (S. pombe) (CDC25B), transcript 6256 CDC25B 994 12.59 -1.14 1.73E-03 variant 2, mRNA. 159832 na 0 10.91 -1.10 1.73E-03 Homo sapiens cDNA FLJ34585 fis, clone KIDNE2008758. Homo sapiens pyridoxal-dependent decarboxylase domain containing 1 (PDXDC1), 78558 PDXDC1 23042 10.79 -1.16 1.73E-03 X mRNA. 30929 HYPK 25764 12.88 1.16 1.73E-03 Homo sapiens Huntingtin interacting protein K (HYPK), mRNA. 88522 IL13RA2 3598 9.16 -2.55 1.73E-03 Homo sapiens interleukin 13 receptor, alpha 2 (IL13RA2), mRNA. Homo sapiens actin related protein 2/3 complex, subunit 5, 16kDa (ARPC5), 11313 ARPC5 10092 12.73 -1.70 1.73E-03 X mRNA. Homo sapiens cell division cycle associated 7-like (CDCA7L), transcript variant 1, 34411 CDCA7L 55536 10.61 -1.11 1.73E-03 mRNA. 39384 AEN 64782 11.43 0.83 1.89E-03 Homo sapiens apoptosis enhancing nuclease (AEN), mRNA. 51421 na 0 7.74 1.31 1.89E-03 Homo sapiens clone HQ0514 PRO0514 mRNA, complete cds. 236 CIT 11113 10.73 -1.26 1.97E-03 X Homo sapiens citron (rho-interacting, serine/threonine kinase 21) (CIT), mRNA. 87542 ACTN1 87 12.88 -1.12 1.97E-03 X Homo sapiens actinin, alpha 1 (ACTN1), transcript variant 2, mRNA. 78491 na 0 7.86 1.33 2.00E-03 Homo sapiens, clone IMAGE:4042121, mRNA, partial cds. 37093 SRPRB 58477 12.11 0.84 2.00E-03 Homo sapiens signal recognition particle receptor, B subunit (SRPRB), mRNA. 28946 HHAT 55733 8.34 1.05 2.07E-03 Homo sapiens hedgehog acyltransferase (HHAT), transcript variant 1, mRNA. 155523 UCA1 652995 10.58 1.97 2.07E-03 Homo sapiens cDNA FLJ35082 fis, clone PLACE6005351. 66999 CYorf16 252946 11.43 -1.39 2.18E-03 Homo sapiens chromosome Y open reading frame 16 (CYorf16), non-coding RNA. Homo sapiens sorbin and SH3 domain containing 1 (SORBS1), transcript variant 6, 164602 SORBS1 10580 9.22 -0.96 2.14E-03 X mRNA. Homo sapiens PH domain and leucine rich repeat protein phosphatase-like 1517 PHLPPL 23035 10.64 1.00 2.24E-03 (PHLPPL), mRNA. 57652 C20orf108 116151 8.33 -1.21 2.26E-03 X Homo sapiens chromosome 20 open reading frame 108 (C20orf108), mRNA. 19979 MMD 23531 12.34 -1.09 2.26E-03 Homo sapiens monocyte to macrophage differentiation-associated (MMD), mRNA. 31972 TMEM51 55092 11.49 -0.87 2.37E-03 Homo sapiens transmembrane protein 51 (TMEM51), transcript variant 4, mRNA. Homo sapiens leucine zipper-EF-hand containing transmembrane protein 2 57073 LETM2 137994 11.47 0.71 2.42E-03 (LETM2), mRNA. Homo sapiens vesicle-associated membrane protein 2 (synaptobrevin 2) (VAMP2), 22197 VAMP2 6844 10.22 -1.13 2.49E-03 X mRNA. Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 4, 88479 CD44 960 13.27 -1.35 2.49E-03 mRNA. Homo sapiens KTI12 homolog, chromatin associated (S. cerevisiae) (KTI12), 111485 KTI12 112970 10.57 0.93 2.72E-03 mRNA. 112155 CA12 771 10.77 -2.17 2.72E-03 X Homo sapiens carbonic anhydrase XII (CA12), transcript variant 1, mRNA. 149544 na 0 8.33 -0.84 2.72E-03 Homo sapiens, clone IMAGE:3922927, mRNA. 50293 ATOH8 84913 8.60 -2.17 2.86E-03 Homo sapiens atonal homolog 8 (Drosophila) (ATOH8), mRNA. 5380 STX8 9482 10.54 -1.26 2.86E-03 Homo sapiens syntaxin 8 (STX8), mRNA. Homo sapiens arginase, type II (ARG2), nuclear gene encoding mitochondrial 89225 ARG2 384 10.08 -1.32 2.95E-03 protein, mRNA. 148430 na 0 9.83 -1.08 2.90E-03 Homo sapiens clone 24405 mRNA sequence. Homo sapiens calcium/calmodulin-dependent protein kinase II inhibitor 1 81605 CAMK2N1 55450 12.24 -0.82 3.03E-03 X (CAMK2N1), mRNA. 12744 ZNF239 8187 8.50 0.80 3.03E-03 Homo sapiens zinc finger protein 239 (ZNF239), transcript variant 4, mRNA. 107847 SDC2 6383 12.06 1.90 3.09E-03 X Homo sapiens syndecan 2 (SDC2), mRNA. Homo sapiens non-SMC element 2, MMS21 homolog (S. cerevisiae) (NSMCE2), 84950 NSMCE2 286053 10.56 -0.77 3.09E-03 mRNA. 95084 HMGB1 3146 13.57 -1.69 3.09E-03 X Homo sapiens high-mobility group box 1 (HMGB1), mRNA.