13th Mee�ng of the 13. srečanje Slovenian Biochemical Society Slovenskega biokemijskega društva with Interna�onal Par�cipa�on z mednarodno udeležbo Book of Abstracts 24 ‐ 27 September 2019 Dobrna, Slovenia 13th Meeting of the Slovenian Biochemical Society with International Participation 13. srečanje Slovenskega biokemijskega društva z mednarodno udeležbo Book of Abstracts Knjiga povzetkov Dobrna, 24 ‐ 27 September 2019 i The 13th Meeting of the Slovenian Biochemical Society with International Participation is organised by the Slovenian Biochemical Society and the National Institute of Chemistry, Ljubljana, Slovenia. 13th Meeting of the Slovenian Biochemical Society with International Participation 13. srečanje Slovenskega biokemijskega društva z mednarodno udeležbo Editor: Matic Kisovec Technical Editors: Anja Golob‐Urbanc, Gašper Šolinc Published by: Slovenian Biochemical Society, Ljubljana Reviewed by: Matic Legiša, Anja Golob‐Urbanc, Gašper Šolinc Cover Design by: Matic Kisovec (graphics from vecteezy, freepik, smashicons) Organised by: National Institute of Chemistry, Ljubljana, Slovenia and the Slovenian Biochemical Society Printed by: Tiskarna knjigoveznica Radovljica d.o.o., Radovljica Circulation: 250 Complimentary publication CIP ‐ Kataložni zapis o publikaciji Narodna in univerzitetna knjižnica, Ljubljana 577.1(082) SLOVENIAN Biochemical Society. Meeting with International Participation (13 ; 2019 ; Dobrna) Book of abstracts = Knjiga povzetkov / 13th Meeting of the Slovenian Biochemical Society with International Participation = 13. srečanje Slovenskega biokemijskega društva z mednarodno udeležbo, Dobrna, 24‐27 September 2019 ; [organised by National Institute of Chemistry and the Slovenian Biochemical Society ; editor Matic Kisovec]. ‐ Ljubljana : Slovenian Biochemical Society, 2019 ISBN 978‐961‐93879‐8‐6 1. Kisovec, Matic COBISS.SI‐ID 301584384 ii Table of Contents Table of Contents ............................................................................................................. iii Foreword ........................................................................................................................... v Committees ...................................................................................................................... vi General Information ........................................................................................................ vii Schedule Outline .............................................................................................................. ix Schedule ............................................................................................................................ x Lecture abstracts ............................................................................................................... 1 Poster Abstracts .............................................................................................................. 55 Poster Session I ................................................................................................................ 55 Poster Session II ............................................................................................................. 101 List of Participants ......................................................................................................... 1 7 0 Author Index .................................................................................................................. 179 Sponsors ........................................................................................................................ 185 Notes ............................................................................................................................. 197 iii iv Foreword It is a great pleasure to welcome you at the 13th Meeting of Slovenian Biochemical Society with International Participation in Dobrna. The Meeting is organized by the Slovenian Biochemical Society together with the National Institute of Chemistry, Ljubljana, Slovenia. Like previous meetings, this one aims at displaying most recent developments in biochemistry and related disciplines. The assortment of distinguished international and Slovenian speakers will present new discoveries in biochemistry, molecular biology, genomics, systems biology, cell biology, structural biology, synthetic biology, biotechnology etc. Furthermore, new technologies supporting various disciplines will be presented by the sponsors. This meeting is all about communication and networking between world class scientists, established senior as well as enthusiastic young researchers. The meeting is a great opportunity for exchanging knowledge and experience as well as for establishing new scientific collaborations and connections with industrial partners. We also invite you to participate at the round table discussion on Integrity in science with the lecturer from the FEBS Journal, Cambridge. We also warmly invite you to attend all social events. We wish you all a productive and enjoyable meeting as well as a pleasant stay at Dobrna. Sincerely, Organizing Committee v Committees Organising Committee Mojca Benčina, Chair Marjetka Podobnik, Co‐Chair Vida Forstnerič Anja Golob‐Urbanc Matic Kisovec Duško Lainšček Matic Legiša Mateja Manček Keber Martina Mohorčič Katja Pirc Aleksandra Šakanović Scientific Committee Marjetka Podobnik, Chair Kristina Gruden Iva Hafner Bratkovič Roman Jerala Janko Kos Igor Križaj Jurij Lah Tamara Lah Turnšek Brigita Lenarčič Metka Lenassi Mateja Manček Keber Hrvoje Petković Uroš Potočnik Boris Rogelj Damjana Rozman Kristina Sepčić Boris Turk vi General Information Conference Venue Dobrna, The Ceremony Hall of the Zdraviliški Dom Spa, Dobrna 50, SI‐3204 Dobrna, Slovenia Registration and Information Desk The registration desk will be located in the lobby of the Ceremony Hall of the Zdraviliški Dom Spa. The certificate of attendance will be issued at the registration desk. Registration and Information Desk Opening Hours Tuesday, 24 September 2019, 08:30–18:00 Wednesday, 25 September 2019, 08:00–18:00 Thursday, 26 September 2019, 08:00–16:00 Friday, 27 September 2019, 08:30–12:00 Name Badges All participants are kindly requested to wear badges at all times during the conference. Presentation Preview and Deposition Speakers are kindly requested to deliver their presentations to the computer technician in the conference hall half an hour before the start of the session. Poster Display Poster session I will be held on Tuesday, 24 September 2019 from 18:00 to 21:00 in the lobby of the Ceremony Hall of the Zdraviliški Dom Spa. vii Poster session II will be held on Wednesday, 25 September 2019 from 18:00 to 21:00 in the lobby of the Ceremony Hall of the Zdraviliški Dom Spa. Poster presenters are kindly asked to mount their posters between 10:00 and 16:00 on Tuesday, 24 September 2019 and remove them by Friday, 27 September 2019 before 10:00. Presenters should look‐up the numbers assigned to their posters in the Book of abstracts and pin up their posters on the display boards with the corresponding number. Material for mounting the posters will be available at the venue. Presenters are responsible for setting and removing their posters. Sponsor Exhibitions All sponsors exhibiting at the symposium will have their desks ready in the lobby by Tuesday, 24 September 2019 at 12:00. All tables will be assigned in advance. Social Programme Social programme includes: “Welcome Dinner” on Tuesday, 24 September 2019 from 18:00 to 21:00, “Get Together Dinner” on Wednesday, 25 September 2019 from 18:00 to 21:00, “Conference Dinner” on Thursday, 26 September 2019 at 19:00. Coffee Breaks and Lunch All participants are invited to refreshments during the coffee breaks, which will be held in the lobby of the Ceremony Hall of the Zdraviliški Dom Spa. Lunch will be available for all registered participants, in the Dining room of the Hotel Vita. viii Schedule Outline Tuesday 24 Wednesday 25 Thursday 26 Friday 27 9:00‐9:45 8:30‐10:30 8:30‐10:30 8:30‐10:30 Satellite meeting: Molecular Functional genomics Molecular basis of ERA CoBiotech interactions and and systems biology disease II project MISSION networking 9:45‐10:15 10:30‐11:00 10:30‐11:00 10:45‐11:15 Coffee break Coffee break Coffee break Coffee break 10:15‐12:00 11:00‐13:00 11:00‐12:45 11:15‐12.00 Satellite meeting: Protein Structure and Molecular basis of Closing EMBO lecture ERA CoBiotech Function disease I project MISSION 11:00 → Registration 14:15‐14:30 13:00‐14:00 12:45‐14:00 12:00‐12:15 Opening of 13th Lunch Lunch Closing remarks Meeting of the Slovenian Biochemical Society 14:30‐16:30 14:00‐16:00 14:00‐16:00 Synthetic biology Biotechnology and Cell signalling and bionanotechnology membranes 16:30‐17:15 16:00‐16:30 16:00‐16:30 Coffee break Coffee break Coffee break 17:15‐18:00 16:30‐18:00 16:30‐18:00 Opening FEBS lecture Round table EMBO: SBD assembly Integrity in Science 18:00‐21:00 18:00‐21:00 19:00 → Poster session I and Poster session II and Conference dinner Welcome dinner Get together dinner ix Schedule Tuesday, 24 September 2019 7:20 Bus to Dobrna (from P&R Barje, Ljubljana) 9:00‐12:00 Satellite meeting: ERA CoBiotech project MISSION 9:00‐9:15 Coordinator Andriy Luzhetskyy, Saarland University, DE Welcome and introduction of ERA CoBiotech project MISSION 9:15‐9:45 Chengzhang Fu, Helmholtz institute, DE Cloning of the griselimycin and myxopyronin biosynthetic gene clusters 9:45‐10:15 Coffee break 10:15‐10:45 Hrvoje Petković, University of Ljubljana, SI MISSION chassis for biosynthesis