The International Symposium on Ocular Pharmacology and Therapeutics www.isopt.net 10th ISOPTClinical March 7-10, 2013, Paris, France Program & Abstracts Retina Glaucoma Inflammation & Infection Basic External Eye DevelopmentDrug Science Diseases ISOPT is Celebrating its 10th Anniversary 10th ISOPTClinical Contents Welcome . Committees. General Information. Reception & Refreshments. Sponsors & Exhibitors . Scientific Program Thursday, March 7 . Friday, March 8 . Saturday, March 9. Sunday, March 10 . E-Posters . Abstracts . Index of Authors . 2 The International Symposium on Ocular Pharmacology and Therapeutics March 7-10, 2013, Paris, France Dear Colleague, ISOPT is Celebrating its 10th Anniversary! Over the years ISOPT has become a place for formal updates of medical ophthalmology and drug utilization combined with informal meetings of clinicians and drug developers. ISOPT’s vision is to increase knowledge and awareness of drug usage in ophthalmology, reflecting innovations and their utilization in practice. ISOPT’s vision will be reflected in the following missions: • Share treatment algorithms in major ophthalmic indications. • Implement data from clinical studies for daily practice • Facilitate innovation – connecting innovators with practitioners ISOPT offers a relevant and updated scientific program in a relaxed atmosphere leading to direct interactions of its delegates. We welcome you in Paris, and invite you to share experiences and insights, whether your field of interest is in retinal diseases, inflammation, cornea and external diseases, glaucoma or basic science. Ron Neumann, MD Sara Krupsky, MD Symposium Chairpersons 3 10th ISOPTClinical Committees Chairpersons Special Program Advisor S. Krupsky, Israel B.D. Kuppermann, USA R. Neumann, Israel Scientific Advisory Board P.A. Asbell, USA A. Das, USA P. Kaufman, USA H. Reitsamer, Austria E.K. Akpek, USA T. Das, India J.H. Kim, South Korea V.S. Sangwan, India I. Barequet, Israel M.D. De Smet, Belgium S. Kinoshita, Japan L. Schmetterer, Austria T. Barisani, Austria S. Dikstein, Israel U.B. Kompella, USA G. Soubrane, France F. Behar-Cohen, France J. Duan, China B.D. Kuppermann, USA E. Souied, France P. Bernstein, USA R.M. Feldman, USA P. Lanzetta, Italy D.D-S, Tang Liu, USA R. Beuerman, Singapore S.C. Foster, USA L.A. Levin, USA H.S. Uy, Philippines S. Binder, Austria R.W. Fraunfelder, USA X. Li, China R. Vogel, USA B. Bodaghi, France A. Girach, UK P.N. Nagpal, India X. Zhang, China K. Brazzell, USA R. Gurny, Switzerland T. Nakanashi-Ueda, Japan M. Zierhut, Germany A. Bron, UK G. Hollo, Hungary A. Okada, Japan J.G. Cunha-Vaz, Portugal S. Hong, S. Korea A. Okumura, Japan R. Danis, USA J.B. Jonas, Germany C. Paterson, USA Invited Speakers N. Acar, France I. Chowers, Israel H.E. Killer, Switzerland A. Queant, France B. Ambati, USA K. Colby, USA H. Klassen, USA G. Querques, France J. Ambati, USA M.F. Cordeiro, UK A. Koh, Singapore E. Reichel, USA R.E. Anderson, USA G. Coscas, France U. Kompella, USA M. Rodriguez-Aller, S. Androudi, Greece C. Creuzot, France J.S. Korobelnik, France Switzerland E. Akpek, USA R. Dana, USA R. P. Kowalski, USA E. Romanowski, USA P. Aragona, Italy A. Das, USA R. Kowluru, USA Y. Rotenstreich, Israel Y. Arsenijevic, Switzerland M. de Smet, The Netherlands M. Kramer, Israel D.R. Saban, USA P. Asbell, USA C. Deuter, Germany B.D. Kuppermann, USA J. Sahel, France L. Asmus, Germany C. Di Tommaso, Switzerland W. Lagreze, Germany M. Sainz de la Maza, Spain I. Audo, France G. Dorin, USA F. Lallemand, France B. Salomon, France A. Augustin, Germany J. Dowler, UK P. Lanzetta, Italy M. Sawa, Japan F. Bandello, Italy W. Drexler, Austria P. Le Hoang, France L. Schmetterer, Austria I. Barequet, Israel P. Dugel, USA H.G. Lemij, The Netherlands B. Seitz, Germany T. Barisani-Asenbauer, B. Dupas, France B.P. Leroy, France D. Sinha, USA Austria Y. El-Shabrawi, Austria L. Levin, USA G. Soubrane, France C. Baudouin, France C. Ergorul, USA H. Levkovitch-Verbin, Israel E. Souied, France F. Behar-Cohen, France M. Esmaeelpour, Austria A.S. Lewin, Canada O. Stachs, Germany M.W. Belin, USA M. Eydelman, USA J.M. Liebmann, USA D. Tang-Liu, USA G.J. Berdy, USA N. Farman, France T.M. Lietman, USA J. Thorne, USA P. Bernstein, USA R.W. Fraunfelder, USA J.M. Lloves, Spain A. Torriglia, France R. Beuerman, Singapore P. Garg, India A. Loewenstein, Israel E. Touchard, France S. Binder, Austria G. Garhoefer, Austria E. Lydhal, Sweden R. Toyos, USA B. Bodaghi, France D. Garway-Heath, UK F.J. Malecaze, France O. Ucakhan-Gunduz, Turkey S. Bonini, Italy C. Glittenberg, Austria C. Martinho, Portugal P. Udaondo, Spain F. Boscia, Italy M. Goldstein, Israel N.L. Mata, USA P.T.K. Van, Vietnam D. Boyer, USA R. Gurny, Switzerland J.S. Mehta, Singapore G. Van Setten, Sweden D. Brémond-Gignac, France S.H. Hardarson, Iceland E. Miserocchi, Italy D. Veritti, Italy L. Bretillon, France A. Harris, USA K. Miyake, Japan M. Veurink, Switzerland F. Brignole-Baudouin, France J. Heier, USA S. Mohr, USA M. Vidal-Sanz, Spain A. Bron, France R. Herrero-Vanrell, Spain J. Mones, Spain S. Wadsworth, USA A. Bron, UK D. Hinton, USA Q.D. Nguyen, USA M. Weber, France J. Bullock, USA A. Horsager, USA A. Ohira, Japan D. Zack, USA J. Busik, USA J.F. Huang, USA N. Orwa, Israel M. Zarbin, USA R. Caldwell, USA M.M. Iester, Italy M. Paques, France F. Zeiler, Austria M. Calonge, Spain S. Jain, USA S. Patel, USA M. Zhao, France K.V. Chalam, USA J. Jonas, Germany C. Pavesio, UK M. Zierhut, Germany A.A. Chang, Australia T. Kern, USA J. Penn, USA 4 The International Symposium on Ocular Pharmacology and Therapeutics March 7-10, 2013, Paris, France General Information Venue Marriott Rive Gauche Hotel & Conference Center 17 Boulevard Saint Jacques Paris 75014, France Tel: +33 1 4078 7980 Fax: +33 1 4588 4393 Language English is the official language of the Symposium. Registration and Hospitality The registration desk will be located in the entrance to the meetings halls and will be open as follows: Thursday, 7 March 11:00 – 18:00 Saturday, 9 March 07:30 – 17:30 Friday, 8 March 07:30 – 17:30 Sunday, 10 March 07:30 – 12:00 Symposium Kit and Name Badge Upon registering you will receive your kit, containing your personal name badge. Please remember to wear your name badge to all symposium activities and to the Welcome Reception. Please note there will be a charge of €30 to replace lost badges. Internet Facilities Free internet and e-mail facilities are located in the exhibition area and are available during exhibition opening hours. Please be considerate of fellow participants when using the facilities. Certificate of Attendance A certificate of attendance will be available at the registration desk on Saturday, March 9th, noon time. Exhibition Opening Hours All participants are invited to view the exhibition in the hotel. Exhibition opening hours are as follows: Thursday, 7 March 13:00 - 20:00 Friday, 8 March 10:00 - 18:00 Saturday, 9 March 10:00 - 18:00 Oral Presentations If using a PowerPoint presentation, please note you need to bring it on a CD or on a memory stick (using the USB port in the computer) and load it on one of the Symposium computers in the Speaker Preview Room, at least 1 hour before the start of the session. If combining video films with PowerPoint, please make sure to check it in the session hall where your lecture is taking place during a coffee or lunch break prior to your session, at least 30 minutes before the start of the session. Please note: You cannot use your own personal laptops for the presentation, only the computers available at the Preview room. E-Poster Presentations E-posters will be available for viewing throughout the Symposium in the exhibition area. ISOPT Symposium Secretariat Paragon Conventions 18, Avenue Louis-Casai, 1209 Geneva, Switzerland Tel: +41 22 5330 948, Email: [email protected], Web: www.isopt.net 5 10th ISOPTClinical Reception & Refreshments Welcome Reception 18:00 – Thursday, 7 March All participants are invited to the Welcome Reception at the exhibition area Coffee & Refreshments Sponsored by Coffee will be served in the exhibition area at the times indicated in the Scientific Program Lunch Sessions Lunchboxes will be provided during the sponsored lunch sessions: Friday, March 8th – Sponsored by Saturday, March 9th – Sponsored by 6 The International Symposium on Ocular Pharmacology and Therapeutics March 7-10, 2013, Paris, France Sponsors & Exhibitors Sponsors Exhibitors 7 10th ISOPTClinical Sponsors & Exhibitors Santen Mayumi Fujino 3-9-19 Shimoshinjo, Higashiyodogawa-ku, Osaka 533-8651 Japan Tel: 81-6-6321-7172 Fax: 81-6-6321-7256 Email: [email protected] Website: www.santen.com Santen, one of the oldest ophthalmic pharmaceutical companies in the world, is Japan’s pioneer and leader in ophthalmic pharmaceuticals. Today, we at Santen are focusing our research and development efforts on glaucoma, retinal, and corneal disorders. We are also accelerating our efforts towards globalization to deliver our products and our message of “A clear vision for life®” to people around the world. Alcon Management SA Avenue Louis Casaï 58 1216 Cointrin Switzerland Tel: 41 59 911 2000 Fax: 41 59 911 3000 Alcon’s surgical portfolio includes technologies and devices for cataract, retinal, refractive and glaucoma surgery, such as the INFINITI® vision system for cataract procedures, the CONSTELLATION® vitreoretinal system for retinal operations, and the AcrySof® family of intraocular lenses (IOLs) to treat cataract and refractive errors like presbyopia and astigmatism. Bayer HealthCare Sunny Yang 1000 PO Box, Montville, NJ 07045 USA Tel: 1-973-305-5167 Email: [email protected] Bayer HealthCare, a subgroup of Bayer AG with annual sales of more than EUR 17.2 billion (2011), is one of the world’s leading, innovative companies in the healthcare and medical products industry and is based in Leverkusen, Germany.