2019 24-27 October 2019 Regnum Carya Convention Center, Antalya - Turkey SELECTED CASES www.endobridge.org STEERING COMMITTEE E. Dale Abel President, ES Dolores Shoback Secretary-Treasurer, ES Andrea Giustina President, ESE Aart J Van Der Lely Immediate Past President, ESE Jens Bollerslev Immediate Past Chair, Education Committee, ESE Camilla Schalin-Jäntti Chair, Education Committee, ESE Fusun Saygili President, SEMT Sadi Gundogdu Past President, SEMT Bulent O. Yildiz Founder & President, EndoBridge® Dilek Yazici Scientific Secreteriat, EndoBridge® Ozlem Celik Scientific Secreteriat, EndoBridge® 2 24 - 27 October, 2019 Antalya - Turkey SCIENTIFICSCIENTIFIC PROGRAMME PROGRAM Friday, 25 October 2019 08.40-09.00 Welcome and Introduction to EndoBridge 2019 MAIN HALL 09.00-11.00 Chairs: Ahmet Sadi Gündoğdu, Füsun Saygılı 09.00-09.30 Modern ways to visualise pituitary tumors - Mark Gurnell 09.30-10.00 What is new in the diagnosis and management of acromegaly Sebastian Neggers 10.00-10.30 Treatment of Cushing disease when surgery fails: Individualized case- based approach - Misa Pfeifer 10.30-11.00 Radiotherapy for pituitary tumors - Michael Brada 11.00-11.20 Coffee Break 11.20-12.50 Interactive Case Discussion Sessions HALL A Pituitary - AJ Van Der Lely, Monica Marazuela HALL B Adrenal - Gary Hammer, Özlem Turhan İyidir HALL C Neuroendocrine tumors - Beata Kos - Kudla, Gregory Kaltsas HALL D Male Reproductive Endocrinology - Dimitrios Goulis, Pınar Kadıoğlu 12.50-14.00 Lunch 14.00-15.30 Interactive Case Discussion Sessions HALL A Pituitary - Misa Pfeifer, Sebastian Neggers HALL B Adrenal - Eystein Husebye, Banu Şarer Yürekli HALL C Neuroendocrine tumors - Beata Kos - Kudla, Gregory Kaltsas HALL D Female Reproductive Endocrinology - Djuro Macut, Alessandra Gambineri 15.30-15.50 Coffee Break 15:50-17:50 Chairs: Gary Hammer, İlhan Tarkun 15.50-16.20 Over or undertreatment of adrenal insufficiency: current and emerging aspects - Eystein Husebye 16.20-16.50 Differential diagnosis, investigation and therapy of bilateral adrenal incidentalomas - Gary Hammer 16.50-17.20 Testosterone therapy in men with hypogonadism - Dimitrios Goulis 17.20-17.50 Hirsutism: Practical approaches to diagnosis and treatment Alessandra Gambineri 23 24 - 27 October, 2019 Antalya - Turkey SCIENTIFICSCIENTIFIC PROGRAMME PROGRAM Saturday, 26 October 2019 09.00-11.00 Chairs: Monica Marazuela, İnan Anaforoğlu 09:00-09:30 Treatment of hypothyroidism and evaluation of the efficacy of treatment Georg Brabant 09:30-10:00 Risk stratification in thyroid cancer - Ayşe Kubat Üzüm 10:00-10:30 Autoimmune thyroid disease - mechanistic update - Monica Marazuela 10:30-11:00 Immune check - point inhibitors and endocrine dysfunction Frederic Castinetti 11.00-11.20 Coffee Break 11.20-12.50 Interactive Case Discussion Sessions HALL A Diabetes - Kathleen Wyne, Marianne Andersen HALL B Bone / Calcium - Barbara Obermayer - Pietsch, Dilek Gogas Yavuz HALL C Thyroid - Georg Brabant, Mehtap Çakır HALL D Obesity / lipids - Connie Newman, Oğuzhan Deyneli 12.50-14.00 Lunch 14.00-15.30 Interactive Case Discussion Sessions HALL A Diabetes - Priyathama Vellanki, Samuel Dagogo - Jack HALL B Bone / Calcium - Jens Bollerslev, Joy Wu HALL C Thyroid - Özgür Demir, Dilek Yazıcı HALL D Obesity / lipids - Uberto Pagotto, Alper Sönmez 15.30-15.50 Coffee Break 15:50-17:50 Chairs: Okan Bülent Yıldız, Mine Adaş 15.50-16.20 An update on gestational diabetes - Marianne Andersen 16.20-16.50 Prediabetes: Pathophysiology, prevention and management Samuel Dagogo - Jack 16.50-17.20 Inpatient management of hyperglycemia - Priyathama Vellanki 17.20-17.50 SGLT inhibitors and GLP Receptor Agonists: Role in altering natural history of diabetic complications - Kathleen Wyne 4 24 - 27 October, 2019 Antalya - Turkey 3 SCIENTIFIC PROGRAM SCIENTIFIC PROGRAMME Sunday, 27 October 2019 09.00-11.00 Chairs: Connie Newman, Aysen Akalın 09.00-09.30 Microbiome and metabolic dysfunction - Oluf Pedersen 09.30-10.00 Central mechanisms in control of body weight and their implications for obesity treatment - Uberto Pagotto 10.00-10.30 NASH: Is there a treatment? - Stergios Polyzos 10.30-11.00 How low should LDL be according to guidelines? - Connie Newman 11.00-11.20 Coffee Break 11.20-13.20 Chairs: Andrea Giustina, Ayşegül Atmaca 11.20-11.50 Update on hypoparathyroidism - Heide Siggelkow 11.50-12.20 Pituitary Diseases and Bone - Andrea Giustina 12.20-12.50 Osteoporosis in relation to pregnancy and lactation Barbara Obermayer - Pietsch 12.50-13.20 New modalities in osteoporosis - Joy Wu 13.20-13.30 Closing comments and adjourn Accredited by the European Accreditation Council for Continuing Medical Education (EACCME). 5 24 - 27 October, 2019 Antalya - Turkey 4 CORPORATECORPORATE SYMPOSIASYMPOSIA Friday, 25 October 2019 Setting a path for success in type 2 diabetes management 18:00 - 19:00 Tsvetalina Tankova Chair: Bülent Okan Yıldız Saturday, 26 October 2019 Clinical Experience with SOLIQUA: Innovative Fixed 08:00 - 09:00 Dose Combination Basal Insulin and GLP1-RA Samuel Dagogo - Jack 6 24 - 27 October, 2019 Antalya - Turkey 5 SELECTEDSELECTED CASES CASES DATE TIME HALL SESSION TITLE O - 01 / Misleading insulin-like growth factor 1 (IGF- 1) levels in an acromegalic patient with liver cirrhosis O - 02 / An ACTH Dependent Cyclic Cushing’s 25.10 11:20 - 12:50 A Pituitary Syndrome O - 03 / Central Diabetes Insipidus Unmasked After Kidney Transplant: A Case Report O - 04 / An unusual case with adrenocortical carcinoma presented during pregnancy O - 05 / Adrenal incidentaloma: A case of co- 25.10 11:20 - 12:50 B Adrenal secreating pheochromocytoma(PCC) with Mild Autonomous Cortisol Excess(MACE) O - 06 / A case with nasal type extranodal NK\T-cell lymphoma with bilateral adrenal gland involvement Neuroendocrine O - 07 / Multiple metastatic liver insulinoma 25.10 11:20 - 12:50 C presenting 4 years after resection of the primary tumors tumor Male O - 08 / An isolated FSH deficiency case due to 25.10 11:20 - 12:50 D reproductive {FSHß} subunit promoter polymorphism c.-211G>T endocrinology O - 09 / Atypical site of TSH-secreting pituitary adenoma- A diagnostic challange O - 10 / Cushing's Disease Due to a Pituitary Adenoma surrounding a Suprasellar/Sellar 25.10 14:00 - 15:30 A Pituitary Meningioma: Case Report O - 11 / Pituitary Involvement of Lymphoma without Diabetes Insipidus: An atypical Presentation O - 12 / A case of Erdheim-Chester presented by hypophysitis O - 13 / Rare two causes of Cushing’s Syndrome: Pigmented adrenal cortical adenoma and adrenocorticotropic hormon secreting pheochromocytoma 25.10 14:00 - 15:30 B Adrenal O - 14 / Autoimmune Polyendocrine Syndrome Type 1 (APS I); rare case with full blown clinical manifestation O - 15 / Restorating Fertility in A Woman with 21 OH Deficiency CAH at Classic/Non-Classic Boundary Extremely High C-peptide Levels in Neuroendocrine O - 16 / 25.10 14:00 - 15:30 C Hypoglycemic Nondiabetic Patient: HIRATA Disease tumors O - 17 / A patient with an atypic neck mass lesion 7 24 - 27 October, 2019 Antalya - Turkey 6 SELECTEDSELECTED CASES CASES DATE TIME HALL SESSION TITLE O - 18 / Mauriac syndrome: Elevated liver enzymes 26.10 11:20 - 12:50 A Diabetes and type 1 diabetes O - 19 / Denosumab for managing extreme hypercalcemia of metastatic parathyroid carcinoma O - 20 / An unusual case of Familial Hypocalciuric 26.10 11:20 - 12:50 B Bone/Calcium Hypercalcemia Treated with cinacalcet O - 21 / PTH washout in diagnosis of primary hyperparathyroidism due to intrathyroidal parathyroid adenoma O - 22 / Severe hyponatremia following rhabdomyolysis and acute renal failure in a young patient with undiagnosed hypothyroidism O - 23 / A patient with thyroid hormone resistance that has been diagnosed within pregnancy 26.10 11:20 - 12:50 C Thyroid O - 24 / A thyrotoxicosis case related to cemiplimab treatment O - 25 / Coexistence of Langerhans Cell Histiocytosis and Papillary Thyroid Carcinoma Revealed as the Culprit behind the Diagnosis Autoimmune Thyroiditis O - 26 / May bariatric surgery be effective in 26.10 11:20 - 12:50 D Obesity / Lipids glycemic regulation in the patients with maturity- onset diabetes of the young? O - 27 / Nondiabetic obese patient with three 26.10 14:00 - 15:30 A Diabetes different MODY gene mutations: a unique case O - 28 / Idiopathic hypercalciuria as differential diagnosis of normocalcemic primary hyperparathyroidism 26.10 14:00 - 15:30 B Bone/Calcium O - 29 / An Unusual Case of Symptomatic Hypercalcemia from Graves Disease in a young Filipino female O - 30 / Metastatic papillary thyroid cancer without primary focus O - 31 / Medullary Thyroid Carcinoma Detected In Supraclavicular Lymph Node Biopsy In Essential Thrombocytosis Patient: Micro-Medullary Carcinoma 26.10 14:00 - 15:30 C Thyroid of Thyroid with Skip Metastasis O - 32 / Poorly differentiated thyroid cancer presenting with thyrotoxicosis and disseminated bone metastasis O - 33 / Subacute thyroiditis: A rare cause of thyrotoxicosis during pregnancy O - 34 / Mandibular hypoplasia, deafness, progeroid features and lipodystrophy syndrome with POLD1 mutation: a 26.10 14:00 - 15:30 D Obesity / Lipids novel type lipodystrophy mimicking scleroderma O - 35 / Effectiveness of plasmapheresis in severe hypertriglyceridemia induced pancreatitis 7 8 24 - 27 October, 2019 Antalya - Turkey ORAL PRESENTATIONS 9 24 - 27 October, 2019 Antalya - Turkey O-01 Pituitary MISLEADING INSuLIN-LIkE GROwTh FACTOR 1 (IGF-1) LEvELS IN AN ACROMEGALIC PATIENT wITh LIvER CIRRhOSIS NURDAN GÜL, ÖZLEM SOYLUK SELÇUKBİRİCİK, AYŞE KUBAT ÜZÜM, REFİK TANAKOL, FERİHAN