REACH – A Population database • Rural Effective Affordable Comprehensive Health (REACH) • A Population level dynamic data base • Updated since last decade • GIS mapping of households • Expanded from 50,000 population in Medchal (county) to another 100,000 population in Shamirpet (county) • Motherboard for many research projects LIFE (Longitudinal Indian Family hEalth) Study • Prospective cohort study started in 2009 • To understand the relationship of various factors on birth outcomes and child development • 1227 women enrolled before pregnancy or early pregnancy (1st trimester) • Various measures including biological samples (blood, urine, stool, vaginal swabs, cord blood and meconium) including children screening. • More than 6000 maternal, paternal and child samples in the bio bank. Offshoot from LIFE • Mycoplasma Genatalium, Differentiated Ureaplasma species and pregnancy outcome • To determine the relationship between Vaginal infection with mycoplasma genitalium, Ureaplsma and adverse pregnancy outcomes (spontaneous abortion and preterm birth) MILES (Mobility and Independent Living among Elders Study) • 564 men and women (60 years and more) recruited in 2011 • To examine longitudinally age related chronic conditions and mobility impairment, among Indian older population • Various measures of mobility, physical function, pQCT, carotid ultrasound, vision, hearing, cognitive function, etc. • Completed 3rd year follow up, now planning 4th year follow up visit. TETRA – CHW led intervention • Technology Enabled Community Health Worker led intervention to reduce CVD burden. • Low cost point of care devices and tablet for CHW and telemedicine to facilitate HTN and DM identification and treatment. • Partly funded by HP foundation. Dengue projects • Dengue Sero-prevelance among adults in a outpatient clinic setting. (Completed) • DNG 10: Sero-prevelance of dengue IgG among children 5-10 years in the Medchal area. (Completed) • DNG 09: Prospective community based incidence study of symptomatic dengue in the Shamirpet population. (Initiating) Public Health Implementation projects Ongoing • National Initiative to Strengthen & Coordinate HIV/TB response in India (NISCHIT) – CDC/PEPFAR funded • Laboratory Quality Systems in HIV (LaQSH) – CDC/PEPFAR funded • Strengthening TB Action and Response (STAR) – CDC (GHSA) funded Past • Public Private Partnership in HIV care • Capacity development for Decentralization of HIV program • Training of personnel in HIV program in the country Fogarty grants with University of Pittsburgh • Empowering Indian Health Researchers with Computational Modelling (Ongoing) – Developed synthetic population for a state • Population and Intervention research Training Grant (Final year of grant) – Received a supplemental grant on HIV and Metabolic Syndrome. Other research • Community Access to Cervical Health (CATCH) in collaboration with John Hopkins University (Completed) • HIV research on high risk groups (MSM). • Designing an comprehensive intelligent Acute Respiratory Infection monitor for early detection of pneumonia • Serum Cystatin C as an early Biomarker for Pre- Ecalmpsia • Develop and test 3D printing technology to produce innovative limbs at affordable cost • Many more involving MIMS faculty Infrastructure • MediCiti Institute of Medical Sciences (MIMS) – Hospital with access to patient care. • SHARE INDIA has various trained staff for data collection (both structured and qualitative methods –FGD, IDI etc.) • Data entry capabilities – design software and double key entry • Data center with safety protocols in place • Laboratory and storage of specimen capabilities • Various student opportunities Logistical arrangements As SHARE INDIA is away from the city Hyderabad, various options for – Accommodation – Travel – High speed internet Certain caveats • Biological samples collected in India cannot be shipped outside the country • All collaborative research has to go through the Government of India screening committee • As per some norms, first author of publications need to be from SHARE on the collaborative projects except for students work Contact • www.sharefoundations.org.